Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q3 2025 ▲▼ | Q4 2025 ▲▼ | Change ▲▼ | Q3 2025 ▲▼ | Q4 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Nuvalent Inc | 17,991,024 | 17,248,450 | -742,574 | $1.56B | $1.74B | 22.24% | +$179.16M |
| Brookdale Senior Living Inc.NOTE 3 500 10 1(BKD) | 0 | 0 | 0 | $0 | $427.49M | 5.48% | +$427.49M |
| Cogent Biosciences, Inc.(COGT) | 9,053,118 | 9,043,903 | -9,215 | $130.00M | $321.24M | 4.12% | +$191.24M |
| Praxis Precision Medicines, Inc.(PRAX) | 840,851 | 903,351 | +62,500 | $44.57M | $266.25M | 3.41% | +$221.69M |
| Centene Corporation(CNC) | 9,046,000 | 6,447,998 | -2,598,002 | $322.76M | $265.34M | 3.40% | -$57.43M |
| Viatris Inc.(VTRS) | 24,099,083 | 20,206,170 | -3,892,913 | $238.58M | $251.57M | 3.22% | +$12.99M |
| Revolution Medicines, Inc.(RVMD) | 3,650,342 | 2,894,613 | -755,729 | $170.47M | $230.56M | 2.96% | +$60.08M |
| United Therapeutics Corporation(UTHR) | 425,993 | 425,993 | 0 | $178.58M | $207.57M | 2.66% | +$28.98M |
| Vera Therapeutics, Inc.CL A(VERA) | 3,641,157 | 4,059,695 | +418,538 | $105.81M | $205.58M | 2.64% | +$99.77M |
| Mirum Pharmaceuticals, Inc.NOTE 4 000 5 0(MIRM) | 0 | 0 | 0 | $168.19M | $180.71M | 2.32% | +$12.52M |
| Celcuity Inc.(CELC) | 733,530 | 1,714,000 | +980,470 | $36.24M | $170.95M | 2.19% | +$134.72M |
| Neurocrine Biosciences, Inc.(NBIX) | 1,184,345 | 1,184,345 | 0 | $166.26M | $167.98M | 2.15% | +$1.72M |
| Ionis Pharmaceuticals, Inc.(IONS) | 1,979,669 | 1,979,669 | 0 | $129.51M | $156.61M | 2.01% | +$27.10M |
| Newamsterdam Pharma Company ORDINARY SHARES | 4,266,693 | 4,164,789 | -101,904 | $121.34M | $146.10M | 1.87% | +$24.76M |
| Inspire Medical Systems, Inc.(INSP) | 1,047,694 | 1,505,872 | +458,178 | $77.74M | $138.89M | 1.78% | +$61.15M |
| Legend Biotech CorporationADS(LEGN) | 2,962,338 | 5,932,000 | +2,969,662 | $96.60M | $128.96M | 1.65% | +$32.36M |
| Brookdale Senior Living Inc.(BKD) | 11,641,642 | 11,637,032 | -4,610 | $98.60M | $125.56M | 1.61% | +$26.96M |
| Indivior Plc | 6,986,811 | 3,393,063 | -3,593,748 | $168.45M | $121.74M | 1.56% | -$46.71M |
| Arrowhead Pharmaceuticals, Inc.(ARWR) | 993,000 | 1,832,946 | +839,946 | $34.25M | $121.69M | 1.56% | +$87.44M |
| Larimar Therapeutics, Inc.(LRMR) | 30,606,974 | 30,606,974 | 0 | $98.86M | $116.61M | 1.49% | +$17.75M |
| Catalyst Pharmaceuticals Inc | 4,974,767 | 4,911,161 | -63,606 | $98.00M | $114.63M | 1.47% | +$16.62M |
| AdaptHealth Corp.(AHCO) | 11,477,730 | 11,477,730 | 0 | $102.73M | $114.32M | 1.47% | +$11.59M |
| BioCryst Pharmaceuticals, Inc.(BCRX) | 12,169,000 | 14,341,000 | +2,172,000 | $92.36M | $111.86M | 1.43% | +$19.50M |
| Ionis Pharmaceuticals, Inc.NOTE 1 750 6 1(IONS) | 0 | 0 | 0 | $82.66M | $95.33M | 1.22% | +$12.67M |
| Alignment Healthcare, Inc.NOTE 4 250 11 1(ALHC) | 0 | 0 | 0 | $0 | $92.55M | 1.19% | +$92.55M |
| ARS Pharmaceuticals, Inc.(SPRY) | 7,503,812 | 7,503,812 | 0 | $75.41M | $87.42M | 1.12% | +$12.01M |
| Pharvaris N V COM | 2,442,464 | 3,126,042 | +683,578 | $60.94M | $86.75M | 1.11% | +$25.81M |
| Savara Inc.(SVRA) | 7,964,000 | 13,569,000 | +5,605,000 | $28.43M | $81.82M | 1.05% | +$53.39M |
| IDEAYA Biosciences, Inc.(IDYA) | 2,153,043 | 2,153,043 | 0 | $58.58M | $74.43M | 0.95% | +$15.85M |
| Certara, Inc.(CERT) | 6,739,537 | 7,808,605 | +1,069,068 | $82.36M | $68.79M | 0.88% | -$13.56M |
| Bio Rad Labs IncCL A | 226,070 | 226,070 | 0 | $63.39M | $68.50M | 0.88% | +$5.11M |
| NeoGenomics, Inc.NOTE 0 250 1 1(NEO) | 0 | 0 | 0 | $62.92M | $64.69M | 0.83% | +$1.77M |
| Acadia Healthcare Company, Inc.(ACHC) | 1,189,000 | 4,520,000 | +3,331,000 | $29.44M | $64.14M | 0.82% | +$34.70M |
| BridgeBio Oncology Therapeutics, Inc.(BBOT) | 4,885,446 | 4,885,446 | 0 | $56.57M | $61.17M | 0.78% | +$4.59M |
| Stoke Therapeutics, Inc.(STOK) | 0 | 1,823,500 | +1,823,500 | $0 | $57.88M | 0.74% | +$57.88M |
| Lantheus Holdings, Inc.(LNTH) | 0 | 827,999 | +827,999 | $0 | $55.10M | 0.71% | +$55.10M |
| Structure Therapeutics IncADS | 373,407 | 767,993 | +394,586 | $10.46M | $53.41M | 0.68% | +$42.96M |
| Envista Holdings Corporation(NVST) | 2,294,036 | 2,280,498 | -13,538 | $46.73M | $49.51M | 0.63% | +$2.78M |
| Enhabit Inc COM | 4,747,746 | 4,747,746 | 0 | $38.03M | $43.77M | 0.56% | +$5.74M |
| Kymera Therapeutics, Inc.(KYMR) | 572,258 | 561,170 | -11,088 | $32.39M | $43.66M | 0.56% | +$11.27M |
| CareDx, Inc.(CDNA) | 2,191,000 | 2,191,000 | 0 | $31.86M | $41.28M | 0.53% | +$9.42M |
| Disc Medicine, Inc.(IRON) | 919,403 | 511,163 | -408,240 | $60.75M | $40.59M | 0.52% | -$20.16M |
| Sionna Therapeutics, Inc.(SION) | 970,590 | 970,590 | 0 | $28.55M | $39.93M | 0.51% | +$11.39M |
| LivaNova PLCNOTE 2 500 3 1(LIVN) | 0 | 0 | 0 | $36.86M | $39.73M | 0.51% | +$2.86M |
| Belite Bio, IncADS(BLTE) | 0 | 233,813 | +233,813 | $0 | $37.40M | 0.48% | +$37.40M |
| Day One Biopharmaceuticals I COM | 4,705,413 | 3,723,131 | -982,282 | $33.17M | $34.70M | 0.44% | +$1.53M |
| Phreesia, Inc.(PHR) | 1,116,752 | 1,999,045 | +882,293 | $26.27M | $33.82M | 0.43% | +$7.56M |
| Embecta Corp.(EMBC) | 2,620,421 | 2,752,031 | +131,610 | $36.97M | $32.69M | 0.42% | -$4.28M |
| Veracyte, Inc.(VCYT) | 726,000 | 726,000 | 0 | $24.92M | $30.56M | 0.39% | +$5.64M |
| Lantheus Holdings, Inc.NOTE 2 625 12 1(LNTH) | 0 | 0 | 0 | $26.53M | $28.91M | 0.37% | +$2.38M |
| Beta Bionics, Inc.(BBNX) | 1,168,415 | 938,308 | -230,107 | $23.22M | $28.59M | 0.37% | +$5.37M |
| Ventas, Inc.(VTR) | 354,000 | 354,000 | 0 | $24.78M | $27.39M | 0.35% | +$2.62M |
| Immunocore Holdings plcNOTE 2 500 2 0(IMCR) | 0 | 0 | 0 | $27.04M | $27.08M | 0.35% | +$41.1K |
| Alnylam Pharmaceuticals, Inc.(ALNY) | 67,935 | 67,935 | 0 | $30.98M | $27.01M | 0.35% | -$3.96M |
| Tango Therapeutics, Inc.(TNGX) | 0 | 2,906,946 | +2,906,946 | $0 | $25.76M | 0.33% | +$25.76M |
| Xenon Pharmaceuticals Inc.(XENE) | 542,020 | 542,020 | 0 | $21.76M | $24.29M | 0.31% | +$2.53M |
| Spyre Therapeutics, Inc.(SYRE) | 613,665 | 710,626 | +96,961 | $10.29M | $23.28M | 0.30% | +$13.00M |
| Foghorn Therapeutics Inc.(FHTX) | 3,255,514 | 3,649,211 | +393,697 | $15.92M | $19.71M | 0.25% | +$3.79M |
| Compass Therapeutics, Inc.(CMPX) | 0 | 3,606,000 | +3,606,000 | $0 | $19.36M | 0.25% | +$19.36M |
| Edgewise Therapeutics, Inc.(EWTX) | 765,694 | 765,694 | 0 | $12.42M | $19.00M | 0.24% | +$6.58M |
| Kyverna Therapeutics, Inc.(KYTX) | 0 | 2,000,000 | +2,000,000 | $0 | $18.80M | 0.24% | +$18.80M |
| Taysha Gene Therapies, Inc.(TSHA) | 5,386,000 | 2,722,165 | -2,663,835 | $17.61M | $14.97M | 0.19% | -$2.64M |
| CorMedix Inc.(CRMD) | 3,323,833 | 1,107,944 | -2,215,889 | $38.66M | $12.89M | 0.17% | -$25.77M |
| DFP Healthcare Acquisitions Cor(DFPH) | 3,360,052 | 3,360,052 | 0 | $11.73M | $11.96M | 0.15% | +$235.2K |
| Monopar Therapeutics Inc.(MNPR) | 159,765 | 170,558 | +10,793 | $13.05M | $11.14M | 0.14% | -$1.91M |
| Medline Inc.CL A(MDLN) | 0 | 260,000 | +260,000 | $0 | $10.92M | 0.14% | +$10.92M |
| Omada Health, Inc.(OMDA) | 553,107 | 553,107 | 0 | $12.23M | $8.73M | 0.11% | -$3.50M |
| CalciMedica, Inc.(CALC) | 1,300,000 | 1,300,000 | 0 | $4.00M | $8.57M | 0.11% | +$4.57M |
| Prestige Consumer Healthcare Inc.(PBH) | 64,563 | 69,669 | +5,106 | $4.03M | $4.30M | 0.06% | +$269.1K |
| Cullinan Therapeutics, Inc.(CGEM) | 2,927,013 | 386,169 | -2,540,844 | $17.36M | $4.00M | 0.05% | -$13.36M |
| Veeva Systems Inc.CL A(VEEV) | 0 | 17,711 | +17,711 | $0 | $3.95M | 0.05% | +$3.95M |
| RadNet, Inc.(RDNT) | 39,913 | 49,951 | +10,038 | $3.04M | $3.56M | 0.05% | +$522.2K |
| Labcorp Holdings Inc.(LH) | 1,057 | 13,825 | +12,768 | $303.4K | $3.47M | 0.04% | +$3.16M |
| Enovis Corporation(ENOV) | 69,213 | 127,270 | +58,057 | $2.10M | $3.39M | 0.04% | +$1.29M |
| Alignment Healthcare, Inc.(ALHC) | 102,942 | 164,345 | +61,403 | $1.80M | $3.25M | 0.04% | +$1.45M |
| Quest Diagnostics Incorporated(DGX) | 0 | 18,392 | +18,392 | $0 | $3.19M | 0.04% | +$3.19M |
| TransMedics Group, Inc.(TMDX) | 12,752 | 25,492 | +12,740 | $1.43M | $3.10M | 0.04% | +$1.67M |
| Insulet Corporation(PODD) | 4,480 | 10,616 | +6,136 | $1.38M | $3.02M | 0.04% | +$1.63M |
| Annexon, Inc.(ANNX) | 583,913 | 583,913 | 0 | $1.78M | $2.93M | 0.04% | +$1.15M |
| Biolife Solutions Inc | 111,195 | 120,211 | +9,016 | $2.84M | $2.91M | 0.04% | +$70.1K |
| Chemed Corporation(CHE) | 4,664 | 6,215 | +1,551 | $2.09M | $2.66M | 0.03% | +$570.9K |
| Petco Health and Wellness Company, Inc.(WOOF) | 0 | 936,309 | +936,309 | $0 | $2.63M | 0.03% | +$2.63M |
| OrthoPediatrics Corp.(KIDS) | 194,109 | 144,220 | -49,889 | $3.60M | $2.56M | 0.03% | -$1.04M |
| The Cigna Group(CI) | 0 | 9,203 | +9,203 | $0 | $2.53M | 0.03% | +$2.53M |
| Trupanion, Inc.(TRUP) | 57,045 | 66,438 | +9,393 | $2.47M | $2.48M | 0.03% | +$13.9K |
| ResMed Inc.(RMD) | 0 | 10,104 | +10,104 | $0 | $2.43M | 0.03% | +$2.43M |
| Boston Scientific Corporation(BSX) | 31,312 | 24,941 | -6,371 | $3.06M | $2.38M | 0.03% | -$678.9K |
| DaVita Inc.(DVA) | 18,567 | 20,909 | +2,342 | $2.47M | $2.38M | 0.03% | -$91.5K |
| Doximity, Inc.CL A(DOCS) | 0 | 51,942 | +51,942 | $0 | $2.30M | 0.03% | +$2.30M |
| DexCom, Inc.(DXCM) | 22,287 | 32,943 | +10,656 | $1.50M | $2.19M | 0.03% | +$686.7K |
| iRhythm Holdings, Inc.(IRTC) | 17,262 | 12,099 | -5,163 | $2.97M | $2.15M | 0.03% | -$822.0K |
| Newamsterdam Pharma CompanyW EXP 99 99 999 *W EXP 99/99/999 | 92,787 | 92,787 | 0 | $1.59M | $2.13M | 0.03% | +$546.5K |
| CONMED Corporation(CNMD) | 760,196 | 52,555 | -707,641 | $35.75M | $2.13M | 0.03% | -$33.62M |
| Masimo Corp | 0 | 16,147 | +16,147 | $0 | $2.10M | 0.03% | +$2.10M |
| LeMaitre Vascular, Inc.(LMAT) | 29,959 | 25,815 | -4,144 | $2.62M | $2.09M | 0.03% | -$528.1K |
| 10x Genomics, Inc.CL A(TXG) | 261,188 | 126,574 | -134,614 | $3.05M | $2.06M | 0.03% | -$988.9K |
| AtriCure, Inc.(ATRC) | 87,569 | 52,076 | -35,493 | $3.09M | $2.06M | 0.03% | -$1.03M |
| Avanos Med Inc | 122,899 | 167,061 | +44,162 | $1.42M | $1.88M | 0.02% | +$455.4K |
| CorVel Corporation(CRVL) | 30,216 | 27,629 | -2,587 | $2.34M | $1.87M | 0.02% | -$469.7K |
| Cardinal Health, Inc.(CAH) | 0 | 8,985 | +8,985 | $0 | $1.85M | 0.02% | +$1.85M |