Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q4 2023 ▲▼ | Q1 2024 ▲▼ | Change ▲▼ | Q4 2023 ▲▼ | Q1 2024 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| CAVA GROUP INC(CAVA) | 32,007,990 | 26,507,990 | -5,500,000 | 1,376 | 1,856,885 | 47.86% | +1,855,509 |
| Lexicon Pharmaceuticals Inc(LXRX) | 117,553,284 | 117,553,284 | 0 | 180 | 282,128 | 7.27% | +281,948 |
| Scholar Rock Hldg Corp(SRRK) | 11,259,438 | 11,259,438 | 0 | 212 | 199,968 | 5.15% | +199,756 |
| Kymera Therapeutics Inc(KYMR) | 2,530,735 | 3,027,135 | +496,400 | 64 | 121,691 | 3.14% | +121,626 |
| Arrowhead Pharmaceuticals Inc(ARWR) | 1,028,255 | 3,036,668 | +2,008,413 | 31 | 86,849 | 2.24% | +86,817 |
| Morphic Hldg Inc | 2,138,188 | 2,213,188 | +75,000 | 62 | 77,904 | 2.01% | +77,842 |
| Apellis Pharmaceuticals Inc COM | 1,421,346 | 1,315,282 | -106,064 | 85 | 77,312 | 1.99% | +77,227 |
| SpringWorks Therapeutics Inc | 1,615,348 | 1,415,348 | -200,000 | 59 | 69,663 | 1.80% | +69,604 |
| Crinetics Pharmaceuticals Inc(CRNX) | 0 | 1,390,477 | +1,390,477 | 0 | 65,088 | 1.68% | +65,088 |
| Beigene Ltd(ONC) | 404,480 | 404,782 | +302 | 73 | 63,304 | 1.63% | +63,231 |
| Silence Therapeutics PLC(SLN) | 3,000,000 | 2,779,619 | -220,381 | 52 | 60,040 | 1.55% | +59,988 |
| Dyne Therapeutics Inc(DYN) | 1,217,960 | 1,517,960 | +300,000 | 16 | 43,095 | 1.11% | +43,079 |
| Revolution Medicines Inc(RVMD) | 1,695,949 | 1,318,649 | -377,300 | 49 | 42,500 | 1.10% | +42,451 |
| Kura Oncology Inc(KURA) | 1,768,056 | 1,919,884 | +151,828 | 25 | 40,951 | 1.06% | +40,926 |
| Neumora Therapeutics Inc(NMRA) | 2,552,702 | 2,924,052 | +371,350 | 44 | 40,206 | 1.04% | +40,162 |
| Korro Bio Inc(KRRO) | 418,605 | 419,226 | +621 | 20 | 37,730 | 0.97% | +37,710 |
| Cytokinetics Inc(CYTK) | 1,214,284 | 506,584 | -707,700 | 101 | 35,517 | 0.92% | +35,415 |
| Solid Biosciences Inc | 909,219 | 2,500,000 | +1,590,781 | 6 | 33,300 | 0.86% | +33,294 |
| IGM Biosciences Inc | 3,100,422 | 3,080,422 | -20,000 | 26 | 29,726 | 0.77% | +29,700 |
| Madrigal Pharmaceuticals Inc(MDGL) | 0 | 110,507 | +110,507 | 0 | 29,510 | 0.76% | +29,510 |
| GlycoMimetics Inc | 8,589,064 | 8,589,064 | 0 | 20 | 25,767 | 0.66% | +25,747 |
| WAVE Life Sciences Ltd(WVE) | 3,007,400 | 4,051,400 | +1,044,000 | 15 | 24,997 | 0.64% | +24,982 |
| Prothena Corp PLC SHS | 501,360 | 1,001,360 | +500,000 | 18 | 24,804 | 0.64% | +24,785 |
| Vera Therapeutics Inc(VERA) | 0 | 506,019 | +506,019 | 0 | 21,820 | 0.56% | +21,820 |
| Viking Therapeutics Inc(VKTX) | 0 | 253,863 | +253,863 | 0 | 20,817 | 0.54% | +20,817 |
| Merus N V | 0 | 455,081 | +455,081 | 0 | 20,492 | 0.53% | +20,492 |
| NewAmsterdam Pharma Company ORDINARY SHARES | 0 | 800,000 | +800,000 | 0 | 18,920 | 0.49% | +18,920 |
| Tango Therapeutics Inc(TNGX) | 0 | 2,194,841 | +2,194,841 | 0 | 17,427 | 0.45% | +17,427 |
| Acelyrin Inc | 3,035,888 | 2,405,143 | -630,745 | 23 | 16,235 | 0.42% | +16,212 |
| Alpine Immune Sciences Inc | 50,759 | 405,784 | +355,025 | 1 | 16,085 | 0.41% | +16,084 |
| Centessa Pharmaceuticals PLC | 1,012,500 | 1,412,500 | +400,000 | 8 | 15,961 | 0.41% | +15,953 |
| Gossamer Bio Inc(GOSS) | 12,058,968 | 13,308,968 | +1,250,000 | 11 | 15,705 | 0.40% | +15,694 |
| Edgewise Therapeutics Inc(EWTX) | 0 | 811,718 | +811,718 | 0 | 14,806 | 0.38% | +14,806 |
| Syros Pharmaceuticals Inc | 2,505,013 | 2,505,013 | 0 | 20 | 13,402 | 0.35% | +13,382 |
| Sea Ltd(SE) | 372,000 | 237,500 | -134,500 | 15 | 12,756 | 0.33% | +12,741 |
| Lexeo Therapeutics Inc(LXEO) | 603,435 | 801,716 | +198,281 | 8 | 12,571 | 0.32% | +12,563 |
| Astria Therapeutics Inc | 0 | 884,214 | +884,214 | 0 | 12,445 | 0.32% | +12,445 |
| Amicus Therapeutics Inc COM | 2,026,364 | 1,011,776 | -1,014,588 | 29 | 11,919 | 0.31% | +11,890 |
| Generation Bio Co | 2,814,191 | 2,830,591 | +16,400 | 5 | 11,521 | 0.30% | +11,516 |
| Xenon Pharmaceuticals Inc(XENE) | 0 | 253,387 | +253,387 | 0 | 10,908 | 0.28% | +10,908 |
| Celldex Therapeutics Inc New(CLDX) | 0 | 253,000 | +253,000 | 0 | 10,618 | 0.27% | +10,618 |
| Taysha Gene Therapies Inc(TSHA) | 3,663,104 | 3,687,548 | +24,444 | 6 | 10,583 | 0.27% | +10,577 |
| Denali Therapeutics Inc(DNLI) | 802,899 | 502,899 | -300,000 | 17 | 10,319 | 0.27% | +10,302 |
| Apogee Therapeutics Inc(APGE) | 0 | 152,500 | +152,500 | 0 | 10,134 | 0.26% | +10,134 |
| Erasca Inc(ERAS) | 4,721,194 | 4,721,194 | 0 | 10 | 9,726 | 0.25% | +9,716 |
| Agenus Inc(AGEN) | 15,631,235 | 15,631,235 | 0 | 13 | 9,066 | 0.23% | +9,053 |
| Seer Inc(SEER) | 4,750,000 | 4,750,000 | 0 | 9 | 9,025 | 0.23% | +9,016 |
| Ultragenyx Pharmaceutical Inc(RARE) | 0 | 177,932 | +177,932 | 0 | 8,308 | 0.21% | +8,308 |
| Elevation Oncology Inc | 0 | 1,513,015 | +1,513,015 | 0 | 7,762 | 0.20% | +7,762 |
| Ovid Therapeutics Inc(OVID) | 2,500,000 | 2,500,000 | 0 | 8 | 7,625 | 0.20% | +7,617 |
| Tourmaline Bio Inc | 91,426 | 314,496 | +223,070 | 2 | 7,202 | 0.19% | +7,200 |
| Applied Therapeutics Inc | 0 | 1,009,500 | +1,009,500 | 0 | 6,865 | 0.18% | +6,865 |
| PDD Holdings Inc(PDD) | 32,500 | 56,500 | +24,000 | 5 | 6,568 | 0.17% | +6,563 |
| Structure Therapeutics Inc | 86,600 | 151,780 | +65,180 | 4 | 6,505 | 0.17% | +6,502 |
| Vigil Neuroscience Inc | 1,811,191 | 1,811,191 | 0 | 6 | 6,176 | 0.16% | +6,170 |
| Axsome Therapeutics Inc(AXSM) | 0 | 76,837 | +76,837 | 0 | 6,132 | 0.16% | +6,132 |
| Cartesian Therapeutics Inc | 9,136,635 | 9,136,635 | 0 | 6 | 5,939 | 0.15% | +5,933 |
| Alto Neuroscience Inc(ANRO) | 0 | 350,000 | +350,000 | 0 | 5,373 | 0.14% | +5,373 |
| Black Diamond Therapeutics Inc | 2,046,517 | 1,046,517 | -1,000,000 | 6 | 5,306 | 0.14% | +5,300 |
| Regenxbio Inc(RGNX) | 0 | 250,000 | +250,000 | 0 | 5,268 | 0.14% | +5,268 |
| Allovir Inc | 6,597,167 | 6,597,167 | 0 | 4 | 4,980 | 0.13% | +4,976 |
| Kyverna Therapeutics Inc(KYTX) | 0 | 200,000 | +200,000 | 0 | 4,968 | 0.13% | +4,968 |
| Foghorn Therapeutics Inc.(FHTX) | 720,720 | 720,720 | 0 | 5 | 4,836 | 0.12% | +4,831 |
| Omega Therapeutics Inc | 1,323,530 | 1,323,530 | 0 | 4 | 4,831 | 0.12% | +4,827 |
| Taiwan Semiconductor Mfg Ltd(TSM) | 67,999 | 32,000 | -35,999 | 7 | 4,354 | 0.11% | +4,347 |
| Geron Corp(GERN) | 0 | 1,281,194 | +1,281,194 | 0 | 4,228 | 0.11% | +4,228 |
| Stoke Therapeutics Inc(STOK) | 0 | 300,000 | +300,000 | 0 | 4,050 | 0.10% | +4,050 |
| HOOKIPA Pharma Inc | 5,666,410 | 5,666,410 | 0 | 5 | 4,034 | 0.10% | +4,030 |
| Sagimet Biosciences Inc(SGMT) | 924,771 | 724,771 | -200,000 | 5 | 3,928 | 0.10% | +3,923 |
| Ke Holdings Inc(BEKE) | 250,000 | 275,000 | +25,000 | 4 | 3,776 | 0.10% | +3,772 |
| Repare Therapeutics Inc | 700,000 | 700,000 | 0 | 5 | 3,297 | 0.08% | +3,292 |
| Metagenomi Inc(MGX) | 0 | 300,000 | +300,000 | 0 | 3,165 | 0.08% | +3,165 |
| PepGen Inc(PEPG) | 0 | 200,000 | +200,000 | 0 | 2,940 | 0.08% | +2,940 |
| Adagene Inc | 1,000,000 | 1,020,000 | +20,000 | 2 | 2,856 | 0.07% | +2,854 |
| Gritstone Bio Inc | 0 | 1,030,952 | +1,030,952 | 0 | 2,650 | 0.07% | +2,650 |
| Fate Therapeutics Inc(FATE) | 0 | 360,311 | +360,311 | 0 | 2,645 | 0.07% | +2,645 |
| Vor Biopharma Inc(VOR) | 2,347,424 | 1,000,000 | -1,347,424 | 5 | 2,370 | 0.06% | +2,365 |
| Amazon Com Inc(AMZN) | 12,000 | 12,000 | 0 | 2 | 2,165 | 0.06% | +2,163 |
| Janux Therapeutics Inc(JANX) | 0 | 50,000 | +50,000 | 0 | 1,883 | 0.05% | +1,883 |
| NVIDIA Corporation(NVDA) | 0 | 1,900 | +1,900 | 0 | 1,717 | 0.04% | +1,717 |
| Apple Inc(AAPL) | 0 | 10,000 | +10,000 | 0 | 1,715 | 0.04% | +1,715 |
| Dynatrace Inc(DT) | 0 | 36,000 | +36,000 | 0 | 1,672 | 0.04% | +1,672 |
| Adobe Inc(ADBE) | 0 | 3,100 | +3,100 | 0 | 1,564 | 0.04% | +1,564 |
| New Oriental Ed & Technology(EDU) | 0 | 15,000 | +15,000 | 0 | 1,302 | 0.03% | +1,302 |
| Datadog Inc(DDOG) | 7,500 | 9,600 | +2,100 | 1 | 1,187 | 0.03% | +1,186 |
| Kronos Bio Inc | 842,954 | 842,954 | 0 | 1 | 1,096 | 0.03% | +1,095 |
| Alphabet Inc(GOOG) | 7,800 | 7,000 | -800 | 1 | 1,057 | 0.03% | +1,055 |
| Microsoft Corp(MSFT) | 2,500 | 2,500 | 0 | 1 | 1,052 | 0.03% | +1,051 |
| Snowflake Inc(SNOW) | 0 | 6,500 | +6,500 | 0 | 1,050 | 0.03% | +1,050 |
| Intapp Inc(INTA) | 17,500 | 29,500 | +12,000 | 1 | 1,012 | 0.03% | +1,011 |
| Ironwood Pharmaceuticals Inc(IRWD) | 110,532 | 110,532 | 0 | 1 | 963 | 0.02% | +961 |
| Achilles Therapeutics PLC | 2,255,375 | 755,375 | -1,500,000 | 2 | 944 | 0.02% | +942 |
| Palo Alto Networks Inc(PANW) | 0 | 3,000 | +3,000 | 0 | 852 | 0.02% | +852 |
| Advanced Micro Devices Inc(AMD) | 2,500 | 4,500 | +2,000 | 0 | 812 | 0.02% | +812 |
| Procore Technologies Inc(PCOR) | 9,500 | 9,500 | 0 | 1 | 781 | 0.02% | +780 |
| Pegasystems Inc(PEGA) | 11,500 | 11,500 | 0 | 1 | 743 | 0.02% | +743 |
| MongoDB Inc(MDB) | 1,000 | 2,000 | +1,000 | 0 | 717 | 0.02% | +717 |
| Visa Inc(V) | 2,500 | 2,500 | 0 | 1 | 698 | 0.02% | +697 |
| PayPal Hldgs Inc(PYPL) | 5,000 | 10,000 | +5,000 | 0 | 670 | 0.02% | +670 |
| Confluent Inc | 19,000 | 19,000 | 0 | 0 | 580 | 0.01% | +579 |