Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q1 2024 ▲▼ | Q2 2024 ▲▼ | Change ▲▼ | Q1 2024 ▲▼ | Q2 2024 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| ALNYLAM PHARMACEUTICALS INC(ALNY) | 0 | 250,300 | +250,300 | 0 | 60,823 | 1.21% | +60,823 |
| INTEGER HLDGS CORP(ITGR) | 0 | 349,221 | +349,221 | 0 | 40,436 | 0.80% | +40,436 |
| TENET HEALTHCARE CORP(THC) | 1,173,300 | 1,173,300 | 0 | 123,326 | 156,084 | 3.10% | +32,759 |
| ARGENX SE(ARGX) | 151,600 | 209,100 | +57,500 | 59,688 | 89,921 | 1.79% | +30,233 |
| BOSTON SCIENTIFIC CORP(BSX) | 3,273,000 | 3,273,000 | 0 | 224,168 | 252,054 | 5.01% | +27,886 |
| ENLIVEN THERAPEUTICS INC | 8,998,338 | 7,959,538 | -1,038,800 | 158,281 | 186,014 | 3.70% | +27,734 |
| IONIS PHARMACEUTICALS INC(IONS) | 2,013,033 | 2,372,333 | +359,300 | 87,265 | 113,065 | 2.25% | +25,800 |
| ELI LILLY & CO(LLY) | 360,800 | 337,600 | -23,200 | 280,688 | 305,656 | 6.08% | +24,968 |
| AMGEN INC(AMGN) | 63,400 | 134,900 | +71,500 | 18,026 | 42,150 | 0.84% | +24,124 |
| INTUITIVE SURGICAL INC | 493,100 | 493,100 | 0 | 196,791 | 219,356 | 4.36% | +22,564 |
| UNITEDHEALTH GROUP INC(UNH) | 70,000 | 112,000 | +42,000 | 34,629 | 57,037 | 1.13% | +22,408 |
| THIRD HARMONIC BIO INC | 5,779,071 | 5,779,071 | 0 | 54,554 | 75,128 | 1.49% | +20,573 |
| VERTEX PHARMACEUTICALS INC(VRTX) | 122,700 | 151,000 | +28,300 | 51,290 | 70,777 | 1.41% | +19,487 |
| EXACT SCIENCES CORP(EXK) | 140,400 | 672,416 | +532,016 | 9,696 | 28,410 | 0.56% | +18,714 |
| BIOGEN INC(BIIB) | 900,900 | 900,900 | 0 | 194,261 | 208,847 | 4.15% | +14,586 |
| VIR BIOTECHNOLOGY INC(VIR) | 640,000 | 2,320,102 | +1,680,102 | 6,483 | 20,649 | 0.41% | +14,166 |
| ADC THERAPEUTICS SA(ADCT) | 0 | 4,316,824 | +4,316,824 | 0 | 13,641 | 0.27% | +13,641 |
| DEXCOM INC(DXCM) | 140,300 | 289,900 | +149,600 | 19,460 | 32,869 | 0.65% | +13,409 |
| SAREPTA THERAPEUTICS INC(SRPT) | 697,500 | 646,000 | -51,500 | 90,298 | 102,068 | 2.03% | +11,770 |
| CULLINAN THERAPEUTICS INC(CGEM) | 517,606 | 1,147,655 | +630,049 | 8,820 | 20,015 | 0.40% | +11,195 |
| XENON PHARMACEUTICALS INC(XENE) | 550,000 | 862,362 | +312,362 | 23,678 | 33,623 | 0.67% | +9,946 |
| MERUS N V | 0 | 156,100 | +156,100 | 0 | 9,236 | 0.18% | +9,236 |
| LYELL IMMUNOPHARMA INC(LYEL) | 199,500 | 6,405,098 | +6,205,598 | 445 | 9,287 | 0.18% | +8,843 |
| C4 THERAPEUTICS INC(CCCC) | 0 | 1,513,058 | +1,513,058 | 0 | 6,990 | 0.14% | +6,990 |
| PERSPECTIVE THERAPEUTICS INC(CATX) | 0 | 492,670 | +492,670 | 0 | 4,912 | 0.10% | +4,912 |
| STRUCTURE THERAPEUTICS INC | 0 | 125,000 | +125,000 | 0 | 4,909 | 0.10% | +4,909 |
| DYNE THERAPEUTICS INC(DYN) | 708,400 | 708,400 | 0 | 20,111 | 24,999 | 0.50% | +4,888 |
| IMMATICS N.V(IMTX) | 1,769,708 | 2,006,381 | +236,673 | 18,600 | 23,314 | 0.46% | +4,715 |
| ELEVANCE HEALTH INC(ELV) | 168,100 | 168,100 | 0 | 87,167 | 91,087 | 1.81% | +3,920 |
| AVIDITY BIOSCIENCES INC | 994,100 | 706,475 | -287,625 | 25,369 | 28,860 | 0.57% | +3,490 |
| NEUROCRINE BIOSCIENCES INC(NBIX) | 423,100 | 448,200 | +25,100 | 58,354 | 61,704 | 1.23% | +3,350 |
| PROGYNY INC | 113,300 | 259,900 | +146,600 | 4,322 | 7,436 | 0.15% | +3,113 |
| BIOMX INC(PHGE) | 4,517,589 | 13,773,653 | +9,256,064 | 2,033 | 4,629 | 0.09% | +2,596 |
| TG THERAPEUTICS INC(TGTX) | 0 | 133,200 | +133,200 | 0 | 2,370 | 0.05% | +2,370 |
| ARRIVENT BIOPHARMA INC(AVBP) | 3,027,328 | 3,027,328 | 0 | 54,068 | 56,157 | 1.12% | +2,089 |
| Q32 BIO INC(FIXX) | 2,252,987 | 2,252,987 | 0 | 38,391 | 40,441 | 0.80% | +2,050 |
| REGENERON PHARMACEUTICALS(REGN) | 22,800 | 22,800 | 0 | 21,945 | 23,963 | 0.48% | +2,019 |
| TERNS PHARMACEUTICALS INC | 7,619,135 | 7,619,135 | 0 | 49,982 | 51,886 | 1.03% | +1,905 |
| LEXICON PHARMACEUTICALS INC(LXRX) | 3,542,000 | 5,846,100 | +2,304,100 | 8,501 | 9,821 | 0.20% | +1,321 |
| MORPHIC HLDG INC | 558,500 | 612,500 | +54,000 | 19,659 | 20,868 | 0.41% | +1,209 |
| IKENA ONCOLOGY INC | 3,539,358 | 3,539,358 | 0 | 5,026 | 5,840 | 0.12% | +814 |
| TRAWS PHARMA INC | 0 | 1,045,261 | +1,045,261 | 0 | 467 | 0.01% | +467 |
| CHEMOMAB THERAPEUTICS LTD | 2,241,274 | 2,241,273 | -1 | 1,746 | 2,045 | 0.04% | +299 |
| CORVUS PHARMACEUTICALS INC(CRVS) | 6,943,654 | 6,943,654 | 0 | 12,360 | 12,637 | 0.25% | +278 |
| INSPIREMD INC(NSPR) | 2,133,405 | 2,133,405 | 0 | 5,056 | 5,323 | 0.11% | +267 |
| VIGIL NEUROSCIENCE INC | 448,891 | 448,891 | 0 | 1,531 | 1,796 | 0.04% | +265 |
| SINGULAR GENOMICS SYSTEMS IN | 0 | 18,023 | +18,023 | 0 | 152 | 0.00% | +152 |
| XERIS BIOPHARMA HOLDINGS INC | 80,420 | 80,420 | 0 | 178 | 181 | 0.00% | +3 |
| SINOVAC BIOTECH LTD(SVA) | 2,718,735 | 2,718,735 | 0 | 340,000 | 340,000 | 6.76% | 0 |
| TURNSTONE BIOLOGICS CORP | 3,099,265 | 3,099,265 | 0 | 8,120 | 8,120 | 0.16% | 0 |
| DYNAVAX TECHNOLOGIES CORP | 113,500 | 113,500 | 0 | 1,409 | 1,275 | 0.03% | -134 |
| LAKESHORE BIOPHARMA CO LTD | 1,534,430 | 1,404,280 | -130,150 | 1,105 | 910 | 0.02% | -195 |
| SINGULAR GENOMICS SYSTEMS IN | 540,697 | 0 | -540,697 | 278 | 0 | — | -278 |
| TYRA BIOSCIENCES INC(TYRA) | 768,638 | 768,638 | 0 | 12,606 | 12,291 | 0.24% | -315 |
| ACUTUS MED INC | 2,648,386 | 0 | -2,648,386 | 498 | 0 | — | -498 |
| PMV PHARMACEUTICALS INC(PMVP) | 6,475,291 | 6,475,291 | 0 | 11,008 | 10,490 | 0.21% | -518 |
| KEZAR LIFE SCIENCES INC | 1,927,000 | 1,927,000 | 0 | 1,737 | 1,156 | 0.02% | -581 |
| NEXTCURE INC | 1,141,200 | 1,141,200 | 0 | 2,545 | 1,815 | 0.04% | -730 |
| MILESTONE PHARMACEUTICALS IN(MIST) | 2,000,000 | 2,000,000 | 0 | 3,580 | 2,640 | 0.05% | -940 |
| AMICUS THERAPEUTICS INC COM | 570,300 | 570,300 | 0 | 6,718 | 5,657 | 0.11% | -1,061 |
| KRYSTAL BIOTECH INC(KRYS) | 37,166 | 29,966 | -7,200 | 6,613 | 5,503 | 0.11% | -1,110 |
| CALCIMEDICA INC(CALC) | 297,380 | 0 | -297,380 | 1,237 | 0 | — | -1,237 |
| RHYTHM PHARMACEUTICALS INC(RYTM) | 704,842 | 704,842 | 0 | 30,541 | 28,941 | 0.58% | -1,600 |
| ORIC PHARMACEUTICALS INC(ORIC) | 287,100 | 287,100 | 0 | 3,948 | 2,030 | 0.04% | -1,918 |
| SYNDAX PHARMACEUTICALS INC(SNDX) | 1,749,000 | 1,925,300 | +176,300 | 41,626 | 39,526 | 0.79% | -2,100 |
| BOLT BIOTHERAPEUTICS INC | 1,541,000 | 0 | -1,541,000 | 2,157 | 0 | — | -2,157 |
| ELEVATION ONCOLOGY INC | 941,275 | 941,275 | 0 | 4,829 | 2,541 | 0.05% | -2,287 |
| MINERALYS THERAPEUTICS INC(MLYS) | 2,021,424 | 2,021,424 | 0 | 26,097 | 23,651 | 0.47% | -2,446 |
| EDGEWISE THERAPEUTICS INC(EWTX) | 15,021,721 | 15,021,721 | 0 | 273,996 | 270,541 | 5.38% | -3,455 |
| THERMO FISHER SCIENTIFIC INC(TMO) | 132,000 | 132,000 | 0 | 76,720 | 72,996 | 1.45% | -3,724 |
| SCPHARMACEUTICALS INC | 5,559,528 | 5,559,528 | 0 | 27,909 | 24,184 | 0.48% | -3,725 |
| CYTOKINETICS INC(CYTK) | 682,700 | 812,906 | +130,206 | 47,864 | 44,043 | 0.88% | -3,821 |
| ICON PLC(ICLR) | 174,100 | 174,100 | 0 | 58,489 | 54,575 | 1.08% | -3,914 |
| NKARTA INC(NKTX) | 800,000 | 800,000 | 0 | 8,648 | 4,728 | 0.09% | -3,920 |
| TELA BIO INC(TELA) | 2,835,542 | 2,457,542 | -378,000 | 16,078 | 11,550 | 0.23% | -4,527 |
| APOLLOMICS INC(APLM) | 8,565,456 | 8,565,456 | 0 | 6,424 | 1,806 | 0.04% | -4,618 |
| GERON CORP(GERN) | 12,893,611 | 8,930,252 | -3,963,359 | 42,549 | 37,864 | 0.75% | -4,685 |
| REPARE THERAPEUTICS INC | 3,322,488 | 3,322,488 | 0 | 15,649 | 10,964 | 0.22% | -4,685 |
| VERA THERAPEUTICS INC(VERA) | 675,872 | 675,872 | 0 | 29,144 | 24,453 | 0.49% | -4,691 |
| STRYKER CORPORATION(SYK) | 269,000 | 269,000 | 0 | 96,267 | 91,527 | 1.82% | -4,740 |
| HERON THERAPEUTICS INC(HRTX) | 10,111,550 | 6,512,866 | -3,598,684 | 28,009 | 22,795 | 0.45% | -5,214 |
| FATE THERAPEUTICS INC(FATE) | 1,355,352 | 1,355,352 | 0 | 9,948 | 4,446 | 0.09% | -5,503 |
| PASSAGE BIO INC(PASG) | 10,124,576 | 10,124,576 | 0 | 13,668 | 8,041 | 0.16% | -5,627 |
| X4 PHARMACEUTICALS INC(XFOR) | 7,133,515 | 7,133,515 | 0 | 9,916 | 4,137 | 0.08% | -5,778 |
| NEUMORA THERAPEUTICS INC.(NMRA) | 1,500,000 | 1,500,000 | 0 | 20,625 | 14,745 | 0.29% | -5,880 |
| ABCELLERA BIOLOGICS INC(ABCL) | 4,180,768 | 4,180,768 | 0 | 18,939 | 12,375 | 0.25% | -6,564 |
| CRINETICS PHARMACEUTICALS IN(CRNX) | 1,385,000 | 1,280,800 | -104,200 | 64,832 | 57,367 | 1.14% | -7,465 |
| CYTOMX THERAPEUTICS INC(CTMX) | 3,544,578 | 0 | -3,544,578 | 7,727 | 0 | — | -7,727 |
| PERSPECTIVE THERAPEUTICS INC(CATX) | 6,505,800 | 0 | -6,505,800 | 7,742 | 0 | — | -7,742 |
| NATERA INC(NTRA) | 899,431 | 687,500 | -211,931 | 82,262 | 74,449 | 1.48% | -7,813 |
| 10X GENOMICS INC(TXG) | 225,200 | 0 | -225,200 | 8,452 | 0 | — | -8,452 |
| INVIVYD INC(IVVD) | 2,690,300 | 2,425,800 | -264,500 | 11,945 | 2,668 | 0.05% | -9,277 |
| ACELYRIN INC | 4,001,711 | 4,001,711 | 0 | 27,012 | 17,648 | 0.35% | -9,364 |
| PRELUDE THERAPEUTICS INC(PRLD) | 10,909,256 | 10,909,256 | 0 | 51,710 | 41,564 | 0.83% | -10,146 |
| SI-BONE INC(SIBN) | 3,174,521 | 3,229,977 | +55,456 | 51,967 | 41,764 | 0.83% | -10,203 |
| VENTYX BIOSCIENCES INC | 1,870,456 | 0 | -1,870,456 | 10,288 | 0 | — | -10,288 |
| MERCK & CO INC(MRK) | 1,316,000 | 1,316,000 | 0 | 173,646 | 162,921 | 3.24% | -10,725 |
| VAXCYTE INC(PCVX) | 1,066,131 | 795,900 | -270,231 | 72,827 | 60,098 | 1.19% | -12,729 |
| ADICET BIO INC | 11,447,140 | 11,447,140 | 0 | 26,901 | 13,851 | 0.28% | -13,050 |
| VERONA PHARMA PLC | 3,398,067 | 2,861,801 | -536,266 | 54,675 | 41,382 | 0.82% | -13,293 |