Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q1 2026 ▲▼ | Q2 2026 ▲▼ | Change ▲▼ | Q1 2026 ▲▼ | Q2 2026 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Edgewise Therapeutics, Inc.(EWTX) | 15,518,492 | 15,518,492 | 0 | $488.83M | $630.52M | 11.94% | +$141.68M |
| ENLIVEN THERAPEUTICS INC | 7,959,538 | 6,776,632 | -1,182,906 | $312.01M | $343.91M | 6.51% | +$31.90M |
| Eli Lilly and Company(LLY) | 236,800 | 257,900 | +21,100 | $217.80M | $309.33M | 5.86% | +$91.53M |
| MBX Biosciences, Inc.(MBX) | 3,637,887 | 3,428,736 | -209,151 | $108.59M | $189.27M | 3.58% | +$80.68M |
| SINOVAC BIOTECH LTD(SVA) | 2,718,735 | 2,718,735 | 0 | $184.47M | $184.47M | 3.49% | $0 |
| AstraZeneca PLC(AZN) | 670,200 | 915,700 | +245,500 | $132.18M | $171.08M | 3.24% | +$38.90M |
| STRUCTURE THERAPEUTICS INC | 1,475,403 | 2,209,400 | +733,997 | $71.11M | $118.58M | 2.25% | +$47.46M |
| SIONNA THERAPEUTICS INC | 3,530,702 | 2,555,877 | -974,825 | $141.55M | $112.43M | 2.13% | -$29.11M |
| Corvus Pharmaceuticals, Inc.(CRVS) | 7,165,006 | 7,165,006 | 0 | $104.82M | $107.05M | 2.03% | +$2.22M |
| ARRIVENT BIOPHARMA INC | 3,027,328 | 3,027,328 | 0 | $69.84M | $105.17M | 1.99% | +$35.33M |
| Guardant Health, Inc.(GH) | 435,200 | 583,700 | +148,500 | $40.20M | $87.57M | 1.66% | +$47.37M |
| argenx SE(ARGX) | 136,900 | 92,880 | -44,020 | $99.97M | $86.17M | 1.63% | -$13.80M |
| Merck & Co., Inc.(MRK) | 663,400 | 663,400 | 0 | $79.80M | $85.25M | 1.61% | +$5.45M |
| uniQure N.V.(QURE) | 2,136,149 | 1,807,486 | -328,663 | $34.93M | $83.25M | 1.58% | +$48.33M |
| Praxis Precision Medicines, Inc.(PRAX) | 172,500 | 230,100 | +57,600 | $55.58M | $77.04M | 1.46% | +$21.46M |
| EDWARDS LIFESCIENCES CORP | 1,230,600 | 834,900 | -395,700 | $98.55M | $75.53M | 1.43% | -$23.02M |
| PRELUDE THERAPEUTICS INC | 10,909,256 | 13,724,571 | +2,815,315 | $37.31M | $73.15M | 1.39% | +$35.84M |
| ABIVAX Société Anonyme(ABVX) | 465,700 | 546,522 | +80,822 | $51.86M | $72.83M | 1.38% | +$20.97M |
| Dyne Therapeutics, Inc.(DYN) | 2,917,884 | 3,235,684 | +317,800 | $52.90M | $71.86M | 1.36% | +$18.96M |
| Natera, Inc.(NTRA) | 262,000 | 262,000 | 0 | $52.40M | $71.12M | 1.35% | +$18.72M |
| CG Oncology, Inc.(CGON) | 948,267 | 972,800 | +24,533 | $64.18M | $69.12M | 1.31% | +$4.94M |
| UnitedHealth Group Incorporated(UNH) | 0 | 161,100 | +161,100 | $0 | $66.96M | 1.27% | +$66.96M |
| ARS PHARMACEUTICALS INC | 8,288,510 | 8,288,510 | 0 | $66.56M | $66.39M | 1.26% | -$165.8K |
| Ascendis Pharma A/S(ASND) | 0 | 244,456 | +244,456 | $0 | $65.20M | 1.24% | +$65.20M |
| Humana Inc.(HUM) | 0 | 164,100 | +164,100 | $0 | $65.18M | 1.23% | +$65.18M |
| Cogent Biosciences, Inc.(COGT) | 322,100 | 1,681,300 | +1,359,200 | $12.40M | $65.07M | 1.23% | +$52.67M |
| Boston Scientific Corporation(BSX) | 2,382,100 | 1,483,200 | -898,900 | $149.48M | $63.30M | 1.20% | -$86.17M |
| INTUITIVE SURGICAL INC | 208,700 | 157,900 | -50,800 | $96.21M | $62.79M | 1.19% | -$33.41M |
| Mineralys Therapeutics, Inc.(MLYS) | 2,052,900 | 2,110,300 | +57,400 | $55.61M | $56.94M | 1.08% | +$1.32M |
| ODYSSEY THERAPEUTICS INC | 0 | 3,001,198 | +3,001,198 | $0 | $56.15M | 1.06% | +$56.15M |
| Xenon Pharmaceuticals Inc.(XENE) | 1,059,971 | 892,471 | -167,500 | $61.64M | $53.87M | 1.02% | -$7.77M |
| Arcutis Biotherapeutics, Inc.(ARQT) | 0 | 2,042,000 | +2,042,000 | $0 | $53.54M | 1.01% | +$53.54M |
| Bristol-Myers Squibb Company(BMY) | 925,000 | 925,000 | 0 | $56.10M | $53.30M | 1.01% | -$2.80M |
| Q32 BIO INC | 2,252,987 | 4,127,987 | +1,875,000 | $14.46M | $52.59M | 1.00% | +$38.13M |
| Stryker Corporation(SYK) | 182,500 | 159,100 | -23,400 | $59.97M | $50.09M | 0.95% | -$9.88M |
| Caris Life Sciences, Inc.(CAI) | 2,806,811 | 2,806,811 | 0 | $50.19M | $50.02M | 0.95% | -$168.4K |
| Thermo Fisher Scientific Inc.(TMO) | 46,500 | 90,700 | +44,200 | $22.86M | $45.47M | 0.86% | +$22.62M |
| Palvella Therapeutics, Inc.(PVLA) | 134,600 | 292,360 | +157,760 | $16.78M | $44.68M | 0.85% | +$27.90M |
| Elevance Health, Inc.(ELV) | 114,700 | 114,700 | 0 | $33.58M | $44.36M | 0.84% | +$10.78M |
| SHATTUCK LABS INC | 6,306,127 | 6,306,127 | 0 | $40.55M | $43.76M | 0.83% | +$3.22M |
| UPSTREAM BIO INC | 5,693,589 | 5,693,589 | 0 | $51.24M | $39.40M | 0.75% | -$11.84M |
| CRINETICS PHARMACEUTICALS IN | 999,000 | 999,000 | 0 | $36.28M | $37.38M | 0.71% | +$1.10M |
| Rhythm Pharmaceuticals, Inc.(RYTM) | 314,100 | 322,900 | +8,800 | $27.32M | $35.85M | 0.68% | +$8.53M |
| Syndax Pharmaceuticals, Inc.(SNDX) | 962,300 | 1,542,000 | +579,700 | $22.48M | $33.71M | 0.64% | +$11.23M |
| FORTE BIOSCIENCES INC | 1,196,955 | 1,577,705 | +380,750 | $31.00M | $33.53M | 0.64% | +$2.53M |
| COMPASS THERAPEUTICS INC | 15,219,994 | 15,219,994 | 0 | $80.51M | $33.33M | 0.63% | -$47.18M |
| Nektar Therapeutics(NKTR) | 275,000 | 465,346 | +190,346 | $19.79M | $32.49M | 0.62% | +$12.70M |
| Krystal Biotech, Inc.(KRYS) | 69,100 | 83,200 | +14,100 | $17.85M | $30.92M | 0.59% | +$13.07M |
| PRELUDE THERAPEUTICS INC | 208,700 | 5,680,186 | +5,471,486 | $96.21M | $30.28M | 0.57% | -$65.93M |
| Axsome Therapeutics, Inc.(AXSM) | 213,921 | 117,578 | -96,343 | $36.16M | $28.78M | 0.55% | -$7.38M |
| Kiniksa Pharmaceuticals International, plc(KNSA) | 180,599 | 420,600 | +240,001 | $8.70M | $26.90M | 0.51% | +$18.20M |
| Trevi Therapeutics, Inc.(TRVI) | 2,454,400 | 1,430,293 | -1,024,107 | $29.28M | $26.67M | 0.51% | -$2.61M |
| Disc Medicine, Inc.(IRON) | 1,067,550 | 357,535 | -710,015 | $68.26M | $26.15M | 0.50% | -$42.11M |
| West Pharmaceutical Services, Inc.(WST) | 0 | 70,600 | +70,600 | $0 | $25.35M | 0.48% | +$25.35M |
| RELMADA THERAPEUTICS INC | 4,715,864 | 3,631,195 | -1,084,669 | $32.82M | $25.13M | 0.48% | -$7.69M |
| UroGen Pharma Ltd.(URGN) | 875,487 | 676,187 | -199,300 | $15.74M | $24.88M | 0.47% | +$9.14M |
| SUTRO BIOPHARMA INC | 801,144 | 743,944 | -57,200 | $19.96M | $24.70M | 0.47% | +$4.74M |
| Savara Inc.(SVRA) | 635,000 | 3,959,900 | +3,324,900 | $3.47M | $24.39M | 0.46% | +$20.93M |
| NEUROPACE INC | 2,096,527 | 1,505,125 | -591,402 | $27.57M | $23.92M | 0.45% | -$3.65M |
| AURA BIOSCIENCES INC | 0 | 3,333,333 | +3,333,333 | $0 | $23.67M | 0.45% | +$23.67M |
| ORIC Pharmaceuticals, Inc.(ORIC) | 2,693,929 | 2,015,000 | -678,929 | $34.13M | $21.82M | 0.41% | -$12.31M |
| CYBIN INC | 3,832,843 | 3,271,400 | -561,443 | $18.40M | $21.62M | 0.41% | +$3.23M |
| BioCryst Pharmaceuticals, Inc.(BCRX) | 1,425,200 | 1,852,000 | +426,800 | $13.57M | $18.52M | 0.35% | +$4.95M |
| BIOAGE LABS INC | 711,811 | 752,153 | +40,342 | $12.45M | $18.44M | 0.35% | +$5.99M |
| LEXEO THERAPEUTICS INC | 3,602,450 | 3,947,850 | +345,400 | $20.68M | $18.38M | 0.35% | -$2.30M |
| WHITEHAWK THERAPEUTICS INC | 4,166,000 | 3,934,296 | -231,704 | $14.37M | $18.02M | 0.34% | +$3.65M |
| Definium Therapeutics, Inc.(DFTX) | 804,000 | 365,400 | -438,600 | $15.20M | $17.19M | 0.33% | +$1.99M |
| Spyre Therapeutics, Inc.(SYRE) | 0 | 186,145 | +186,145 | $0 | $16.53M | 0.31% | +$16.53M |
| CORBUS PHARMACEUTICALS HLDGS | 1,737,287 | 1,737,287 | 0 | $16.31M | $16.30M | 0.31% | -$17.4K |
| Vera Therapeutics, Inc.(VERA) | 369,596 | 369,596 | 0 | $14.87M | $15.86M | 0.30% | +$990.5K |
| ALUMIS INC | 548,163 | 548,163 | 0 | $12.08M | $15.43M | 0.29% | +$3.35M |
| EYEPOINT INC | 1,069,147 | 1,069,147 | 0 | $13.78M | $15.29M | 0.29% | +$1.51M |
| Waters Corporation(WAT) | 0 | 40,300 | +40,300 | $0 | $15.11M | 0.29% | +$15.11M |
| MONOPAR THERAPEUTICS INC | 0 | 157,423 | +157,423 | $0 | $14.58M | 0.28% | +$14.58M |
| Travere Therapeutics, Inc.(TVTX) | 0 | 253,000 | +253,000 | $0 | $14.37M | 0.27% | +$14.37M |
| Taysha Gene Therapies, Inc.(TSHA) | 0 | 2,000,000 | +2,000,000 | $0 | $13.62M | 0.26% | +$13.62M |
| Biogen Inc.(BIIB) | 61,600 | 61,600 | 0 | $11.29M | $13.31M | 0.25% | +$2.02M |
| Revolution Medicines, Inc.(RVMD) | 52,000 | 70,500 | +18,500 | $5.06M | $13.20M | 0.25% | +$8.15M |
| Dianthus Therapeutics, Inc.(DNTH) | 0 | 115,000 | +115,000 | $0 | $11.21M | 0.21% | +$11.21M |
| SPRUCE BIOSCIENCES INC | 0 | 200,000 | +200,000 | $0 | $10.80M | 0.20% | +$10.80M |
| LifeStance Health Group, Inc.(LFST) | 500,000 | 947,400 | +447,400 | $3.19M | $10.15M | 0.19% | +$6.96M |
| Erasca, Inc.(ERAS) | 0 | 495,900 | +495,900 | $0 | $9.08M | 0.17% | +$9.08M |
| PROTARA THERAPEUTICS INC | 0 | 2,220,000 | +2,220,000 | $0 | $8.48M | 0.16% | +$8.48M |
| KEROS THERAPEUTICS INC | 759,155 | 759,155 | 0 | $8.38M | $8.12M | 0.15% | -$258.1K |
| Janux Therapeutics, Inc.(JANX) | 983,600 | 524,700 | -458,900 | $13.67M | $8.06M | 0.15% | -$5.61M |
| TECTONIC THERAPEUTIC INC | 226,600 | 226,600 | 0 | $7.00M | $7.79M | 0.15% | +$785.2K |
| ADICET BIO INC | 1,027,944 | 844,787 | -183,157 | $7.00M | $7.30M | 0.14% | +$298.7K |
| PHARVARIS N V COM | 205,400 | 205,400 | 0 | $5.80M | $7.10M | 0.13% | +$1.30M |
| Alto Neuroscience, Inc.(ANRO) | 167,500 | 257,852 | +90,352 | $3.77M | $6.80M | 0.13% | +$3.04M |
| ZENTALIS PHARMACEUTICALS INC | 0 | 1,390,576 | +1,390,576 | $0 | $6.74M | 0.13% | +$6.74M |
| BRIGHT MINDS BIOSCIENCES INC | 40,000 | 93,000 | +53,000 | $2.92M | $6.53M | 0.12% | +$3.61M |
| ALX ONCOLOGY HLDGS INC | 2,866,256 | 2,866,256 | 0 | $5.75M | $5.93M | 0.11% | +$186.3K |
| TRAVERE THERAPEUTICS INC | 0 | 0 | 0 | $0 | $5.89M | 0.11% | +$5.89M |
| XILIO THERAPEUTICS INC | 0 | 592,300 | +592,300 | $0 | $5.67M | 0.11% | +$5.67M |
| BICARA THERAPEUTICS INC | 667,300 | 191,100 | -476,200 | $13.27M | $5.67M | 0.11% | -$7.60M |
| IMAGENEBIO INC | 378,556 | 909,269 | +530,713 | $1.89M | $5.36M | 0.10% | +$3.47M |
| PROTAGONIST THERAPEUTICS INC | 42,100 | 42,100 | 0 | $4.44M | $5.16M | 0.10% | +$723.3K |
| Alnylam Pharmaceuticals, Inc.(ALNY) | 119,000 | 17,000 | -102,000 | $39.37M | $5.12M | 0.10% | -$34.26M |
| PALISADE BIO INC | 2,333,000 | 2,333,000 | 0 | $4.08M | $4.88M | 0.09% | +$793.2K |
| REVOLUTION MEDICINES INC | 0 | 0 | 0 | $0 | $4.38M | 0.08% | +$4.38M |