Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q2 2024 ▲▼ | Q3 2024 ▲▼ | Change ▲▼ | Q2 2024 ▲▼ | Q3 2024 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| EDGEWISE THERAPEUTICS INC(EWTX) | 15,021,721 | 15,021,721 | 0 | 270,541 | 400,930 | 7.34% | +130,389 |
| MBX BIOSCIENCES INC(MBX) | 0 | 3,812,215 | +3,812,215 | 0 | 99,041 | 1.81% | +99,041 |
| Q32 BIO INC(FIXX) | 2,252,987 | 2,252,987 | 0 | 40,441 | 100,528 | 1.84% | +60,087 |
| UNITEDHEALTH GROUP INC(UNH) | 112,000 | 179,000 | +67,000 | 57,037 | 104,658 | 1.92% | +47,621 |
| ARS PHARMACEUTICALS INC(SPRY) | 9,240,887 | 8,288,510 | -952,377 | 78,640 | 120,183 | 2.20% | +41,543 |
| AMGEN INC(AMGN) | 134,900 | 252,300 | +117,400 | 42,150 | 81,294 | 1.49% | +39,144 |
| UNIVERSAL HLTH SVCS INC(UHS) | 0 | 156,000 | +156,000 | 0 | 35,726 | 0.65% | +35,726 |
| INTEGER HLDGS CORP(ITGR) | 349,221 | 575,000 | +225,779 | 40,436 | 74,750 | 1.37% | +34,314 |
| STRYKER CORPORATION(SYK) | 269,000 | 344,400 | +75,400 | 91,527 | 124,418 | 2.28% | +32,891 |
| BIOAGE LABS INC(BIOA) | 0 | 1,423,470 | +1,423,470 | 0 | 29,608 | 0.54% | +29,608 |
| PHATHOM PHARMACEUTICALS INC(PHAT) | 0 | 1,449,073 | +1,449,073 | 0 | 26,199 | 0.48% | +26,199 |
| CG ONCOLOGY INC(CGON) | 0 | 691,114 | +691,114 | 0 | 26,076 | 0.48% | +26,076 |
| CORVUS PHARMACEUTICALS INC(CRVS) | 6,943,654 | 6,943,654 | 0 | 12,637 | 36,662 | 0.67% | +24,025 |
| REGENERON PHARMACEUTICALS(REGN) | 22,800 | 45,200 | +22,400 | 23,963 | 47,516 | 0.87% | +23,553 |
| BOSTON SCIENTIFIC CORP(BSX) | 3,273,000 | 3,273,000 | 0 | 252,054 | 274,277 | 5.02% | +22,224 |
| ARGENX SE(ARGX) | 209,100 | 204,500 | -4,600 | 89,921 | 110,855 | 2.03% | +20,934 |
| AVIDITY BIOSCIENCES INC | 706,475 | 1,044,805 | +338,330 | 28,860 | 47,988 | 0.88% | +19,128 |
| CORBUS PHARMACEUTICALS HLDGS(CRBP) | 0 | 912,552 | +912,552 | 0 | 18,826 | 0.34% | +18,826 |
| COMPASS THERAPEUTICS INC(CMPX) | 22,362,850 | 22,362,850 | 0 | 22,363 | 41,148 | 0.75% | +18,785 |
| C4 THERAPEUTICS INC(CCCC) | 1,513,058 | 4,377,900 | +2,864,842 | 6,990 | 24,954 | 0.46% | +17,964 |
| EXACT SCIENCES CORP(EXK) | 672,416 | 679,816 | +7,400 | 28,410 | 46,309 | 0.85% | +17,899 |
| ENLIVEN THERAPEUTICS INC | 7,959,538 | 7,959,538 | 0 | 186,014 | 203,287 | 3.72% | +17,272 |
| SAREPTA THERAPEUTICS INC(SRPT) | 646,000 | 954,500 | +308,500 | 102,068 | 119,208 | 2.18% | +17,140 |
| MEDPACE HLDGS INC(MEDP) | 0 | 44,900 | +44,900 | 0 | 14,988 | 0.27% | +14,988 |
| ARRIVENT BIOPHARMA INC(AVBP) | 3,027,328 | 3,027,328 | 0 | 56,157 | 71,142 | 1.30% | +14,985 |
| NATERA INC(NTRA) | 687,500 | 687,500 | 0 | 74,449 | 87,278 | 1.60% | +12,829 |
| GILEAD SCIENCES INC(GILD) | 0 | 151,700 | +151,700 | 0 | 12,719 | 0.23% | +12,719 |
| BIONTECH SE(BNTX) | 0 | 103,000 | +103,000 | 0 | 12,233 | 0.22% | +12,233 |
| STRUCTURE THERAPEUTICS INC | 125,000 | 383,705 | +258,705 | 4,909 | 16,841 | 0.31% | +11,932 |
| ACADIA PHARMACEUTICALS INC | 0 | 764,600 | +764,600 | 0 | 11,760 | 0.22% | +11,760 |
| TERNS PHARMACEUTICALS INC | 7,619,135 | 7,562,971 | -56,164 | 51,886 | 63,075 | 1.15% | +11,189 |
| AVALO THERAPEUTICS INC(AVTX) | 0 | 967,000 | +967,000 | 0 | 9,187 | 0.17% | +9,187 |
| ALNYLAM PHARMACEUTICALS INC(ALNY) | 250,300 | 250,300 | 0 | 60,823 | 68,840 | 1.26% | +8,017 |
| LEXICON PHARMACEUTICALS INC(LXRX) | 5,846,100 | 11,024,000 | +5,177,900 | 9,821 | 17,308 | 0.32% | +7,486 |
| OSCAR HEALTH INC(OSCR) | 0 | 351,618 | +351,618 | 0 | 7,458 | 0.14% | +7,458 |
| APOGEE THERAPEUTICS INC(APGE) | 379,130 | 379,130 | 0 | 14,919 | 22,270 | 0.41% | +7,351 |
| DISC MEDICINE INC(IRON) | 1,785,571 | 1,785,571 | 0 | 80,476 | 87,743 | 1.61% | +7,267 |
| BICARA THERAPEUTICS INC | 0 | 271,910 | +271,910 | 0 | 6,926 | 0.13% | +6,926 |
| PEPGEN INC(PEPG) | 0 | 797,358 | +797,358 | 0 | 6,817 | 0.12% | +6,817 |
| VIR BIOTECHNOLOGY INC(VIR) | 2,320,102 | 3,573,000 | +1,252,898 | 20,649 | 26,762 | 0.49% | +6,113 |
| TYRA BIOSCIENCES INC(TYRA) | 768,638 | 768,638 | 0 | 12,291 | 18,071 | 0.33% | +5,780 |
| LONGBOARD PHARMACEUTICALS IN | 0 | 170,000 | +170,000 | 0 | 5,666 | 0.10% | +5,666 |
| VERA THERAPEUTICS INC(VERA) | 675,872 | 675,872 | 0 | 24,453 | 29,874 | 0.55% | +5,420 |
| NEUMORA THERAPEUTICS INC.(NMRA) | 1,500,000 | 1,500,000 | 0 | 14,745 | 19,815 | 0.36% | +5,070 |
| SI-BONE INC(SIBN) | 3,229,977 | 3,305,801 | +75,824 | 41,764 | 46,215 | 0.85% | +4,451 |
| VERASTEM INC(VSTM) | 1,529,115 | 2,862,448 | +1,333,333 | 4,557 | 8,559 | 0.16% | +4,002 |
| ARDENT HEALTH PARTNERS INC(ARDT) | 0 | 206,000 | +206,000 | 0 | 3,786 | 0.07% | +3,786 |
| TRAWS PHARMA INC(TRAW) | 0 | 605,531 | +605,531 | 0 | 3,561 | 0.07% | +3,561 |
| SCPHARMACEUTICALS INC | 5,559,528 | 6,059,528 | +500,000 | 24,184 | 27,631 | 0.51% | +3,448 |
| XTANT MED HLDGS INC(XTNT) | 73,114,592 | 73,114,592 | 0 | 46,062 | 49,425 | 0.90% | +3,363 |
| THIRD HARMONIC BIO INC | 5,779,071 | 5,779,071 | 0 | 75,128 | 78,306 | 1.43% | +3,178 |
| ADICET BIO INC | 11,447,140 | 11,447,140 | 0 | 13,851 | 16,484 | 0.30% | +2,633 |
| INSTIL BIO INC(TIL) | 0 | 33,700 | +33,700 | 0 | 2,269 | 0.04% | +2,269 |
| XENON PHARMACEUTICALS INC(XENE) | 862,362 | 911,420 | +49,058 | 33,623 | 35,883 | 0.66% | +2,259 |
| ACELYRIN INC | 4,001,711 | 4,001,711 | 0 | 17,648 | 19,728 | 0.36% | +2,081 |
| NKARTA INC(NKTX) | 800,000 | 1,480,600 | +680,600 | 4,728 | 6,692 | 0.12% | +1,964 |
| BIOMX INC(PHGE) | 0 | 1,787,767 | +1,787,767 | 0 | 1,824 | 0.03% | +1,824 |
| FATE THERAPEUTICS INC(FATE) | 1,355,352 | 1,680,580 | +325,228 | 4,446 | 5,882 | 0.11% | +1,436 |
| KEROS THERAPEUTICS INC(KROS) | 1,268,734 | 1,018,734 | -250,000 | 57,981 | 59,158 | 1.08% | +1,177 |
| CHEMOMAB THERAPEUTICS LTD | 2,241,273 | 1,741,273 | -500,000 | 2,045 | 2,734 | 0.05% | +689 |
| ADC THERAPEUTICS SA(ADCT) | 4,316,824 | 4,533,801 | +216,977 | 13,641 | 14,281 | 0.26% | +640 |
| X4 PHARMACEUTICALS INC(XFOR) | 7,133,515 | 7,133,515 | 0 | 4,137 | 4,774 | 0.09% | +637 |
| MINERALYS THERAPEUTICS INC(MLYS) | 2,021,424 | 2,002,939 | -18,485 | 23,651 | 24,256 | 0.44% | +605 |
| REPARE THERAPEUTICS INC | 3,322,488 | 3,322,488 | 0 | 10,964 | 11,429 | 0.21% | +465 |
| DYNE THERAPEUTICS INC(DYN) | 708,400 | 708,400 | 0 | 24,999 | 25,446 | 0.47% | +446 |
| AMICUS THERAPEUTICS INC COM | 570,300 | 570,300 | 0 | 5,657 | 6,091 | 0.11% | +433 |
| MILESTONE PHARMACEUTICALS IN(MIST) | 2,000,000 | 2,000,000 | 0 | 2,640 | 3,040 | 0.06% | +400 |
| INSPIREMD INC(NSPR) | 2,133,405 | 2,133,405 | 0 | 5,323 | 5,718 | 0.10% | +394 |
| KEZAR LIFE SCIENCES INC | 1,927,000 | 1,927,000 | 0 | 1,156 | 1,490 | 0.03% | +334 |
| IKENA ONCOLOGY INC | 3,539,358 | 3,539,358 | 0 | 5,840 | 6,123 | 0.11% | +283 |
| XERIS BIOPHARMA HOLDINGS INC | 80,420 | 80,420 | 0 | 181 | 229 | 0.00% | +48 |
| SINOVAC BIOTECH LTD(SVA) | 2,718,735 | 2,718,735 | 0 | 340,000 | 340,000 | 6.22% | 0 |
| SINGULAR GENOMICS SYSTEMS IN | 18,023 | 0 | -18,023 | 152 | 0 | — | -152 |
| NEXTCURE INC | 1,141,200 | 1,141,200 | 0 | 1,815 | 1,563 | 0.03% | -251 |
| VIGIL NEUROSCIENCE INC | 448,891 | 448,891 | 0 | 1,796 | 1,526 | 0.03% | -269 |
| IMMATICS N.V(IMTX) | 2,006,381 | 2,006,381 | 0 | 23,314 | 22,893 | 0.42% | -421 |
| TRAWS PHARMA INC | 1,045,261 | 0 | -1,045,261 | 467 | 0 | — | -467 |
| VERTEX PHARMACEUTICALS INC(VRTX) | 151,000 | 151,000 | 0 | 70,777 | 70,227 | 1.29% | -550 |
| PMV PHARMACEUTICALS INC(PMVP) | 6,475,291 | 6,475,291 | 0 | 10,490 | 9,648 | 0.18% | -842 |
| LYELL IMMUNOPHARMA INC(LYEL) | 6,405,098 | 6,086,001 | -319,097 | 9,287 | 8,399 | 0.15% | -889 |
| INVIVYD INC(IVVD) | 2,425,800 | 1,728,300 | -697,500 | 2,668 | 1,763 | 0.03% | -906 |
| LAKESHORE BIOPHARMA CO LTD | 1,404,280 | 0 | -1,404,280 | 910 | 0 | — | -910 |
| PASSAGE BIO INC(PASG) | 10,124,576 | 9,822,876 | -301,700 | 8,041 | 6,876 | 0.13% | -1,165 |
| KRYSTAL BIOTECH INC(KRYS) | 29,966 | 23,500 | -6,466 | 5,503 | 4,278 | 0.08% | -1,225 |
| DYNAVAX TECHNOLOGIES CORP | 113,500 | 0 | -113,500 | 1,275 | 0 | — | -1,275 |
| ABCELLERA BIOLOGICS INC(ABCL) | 4,180,768 | 4,180,768 | 0 | 12,375 | 10,870 | 0.20% | -1,505 |
| APOLLOMICS INC(APLM) | 8,565,456 | 0 | -8,565,456 | 1,806 | 0 | — | -1,806 |
| ELEVATION ONCOLOGY INC | 941,275 | 941,275 | 0 | 2,541 | 565 | 0.01% | -1,977 |
| NEUROPACE INC(NPCE) | 3,406,335 | 3,406,335 | 0 | 25,752 | 23,742 | 0.43% | -2,010 |
| ORIC PHARMACEUTICALS INC(ORIC) | 287,100 | 0 | -287,100 | 2,030 | 0 | — | -2,030 |
| CULLINAN THERAPEUTICS INC(CGEM) | 1,147,655 | 1,070,055 | -77,600 | 20,015 | 17,913 | 0.33% | -2,102 |
| BIOMARIN PHARMACEUTICAL INC(BMRN) | 26,100 | 0 | -26,100 | 2,149 | 0 | — | -2,149 |
| TG THERAPEUTICS INC(TGTX) | 133,200 | 0 | -133,200 | 2,370 | 0 | — | -2,370 |
| SYNDAX PHARMACEUTICALS INC(SNDX) | 1,925,300 | 1,925,300 | 0 | 39,526 | 37,062 | 0.68% | -2,464 |
| EVOLENT HEALTH INC(EVH) | 2,605,615 | 1,665,115 | -940,500 | 49,819 | 47,089 | 0.86% | -2,730 |
| SCHOLAR ROCK HLDG CORP(SRRK) | 1,074,382 | 742,300 | -332,082 | 8,950 | 5,946 | 0.11% | -3,004 |
| CYTOKINETICS INC(CYTK) | 812,906 | 766,906 | -46,000 | 44,043 | 40,493 | 0.74% | -3,551 |
| CRINETICS PHARMACEUTICALS IN(CRNX) | 1,280,800 | 1,050,055 | -230,745 | 57,367 | 53,658 | 0.98% | -3,709 |
| BIOMX INC(PHGE) | 13,773,653 | 0 | -13,773,653 | 4,629 | 0 | — | -4,629 |
| PERSPECTIVE THERAPEUTICS INC(CATX) | 492,670 | 0 | -492,670 | 4,912 | 0 | — | -4,912 |