Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q4 2025 ▲▼ | Q1 2026 ▲▼ | Change ▲▼ | Q4 2025 ▲▼ | Q1 2026 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Kymera Therapeutics, Inc.(KYMR) | 5,502,710 | 5,502,710 | 0 | $428.17M | $458.32M | 14.60% | +$30.15M |
| MoonLake ImmunotherapeuticsCL A(MLTX) | 19,751,284 | 16,001,284 | -3,750,000 | $260.32M | $298.26M | 9.50% | +$37.94M |
| Revolution Medicines, Inc.(RVMD) | 3,356,782 | 2,856,782 | -500,000 | $267.37M | $277.82M | 8.85% | +$10.45M |
| Nektar Therapeutics(NKTR) | 1,559,595 | 2,559,595 | +1,000,000 | $65.94M | $184.16M | 5.87% | +$118.22M |
| Structure Therapeutics IncADS | 3,479,022 | 3,459,358 | -19,664 | $241.97M | $166.74M | 5.31% | -$75.22M |
| Mirum Pharmaceuticals, Inc.(MIRM) | 1,495,290 | 1,584,727 | +89,437 | $118.11M | $146.40M | 4.66% | +$28.28M |
| GH Research PLC(GHRS) | 8,827,712 | 8,650,158 | -177,554 | $112.11M | $121.62M | 3.87% | +$9.51M |
| Palvella Therapeutics, Inc.(PVLA) | 879,009 | 960,989 | +81,980 | $92.01M | $119.79M | 3.82% | +$27.78M |
| Zymeworks Inc.(ZYME) | 3,938,641 | 3,734,142 | -204,499 | $103.70M | $93.50M | 2.98% | -$10.20M |
| Xencor, Inc.(XNCR) | 7,133,720 | 7,133,720 | 0 | $109.22M | $86.03M | 2.74% | -$23.18M |
| Stoke Therapeutics, Inc.(STOK) | 2,265,674 | 2,547,557 | +281,883 | $71.91M | $82.95M | 2.64% | +$11.04M |
| Cullinan Therapeutics, Inc.(CGEM) | 5,750,683 | 5,750,683 | 0 | $59.52M | $81.72M | 2.60% | +$22.20M |
| Disc Medicine, Inc.(IRON) | 650,000 | 1,272,312 | +622,312 | $51.62M | $81.35M | 2.59% | +$29.74M |
| Xoma Royalty Corporation | 2,590,303 | 2,590,303 | 0 | $68.88M | $81.26M | 2.59% | +$12.38M |
| Olema Pharmaceuticals, Inc.(OLMA) | 5,295,893 | 5,295,893 | 0 | $132.40M | $78.96M | 2.52% | -$53.44M |
| Tyra Biosciences, Inc.(TYRA) | 2,127,665 | 1,976,196 | -151,469 | $55.94M | $75.69M | 2.41% | +$19.75M |
| Monte Rosa Therapeutics, Inc.(GLUE) | 3,835,886 | 4,460,886 | +625,000 | $60.15M | $73.38M | 2.34% | +$13.23M |
| Alkermes plcSHS(ALKS) | 0 | 2,000,000 | +2,000,000 | $0 | $70.72M | 2.25% | +$70.72M |
| Kura Oncology, Inc.(KURA) | 8,617,162 | 8,445,769 | -171,393 | $89.53M | $68.66M | 2.19% | -$20.87M |
| AC Immune SASHS(ACIU) | 19,822,436 | 19,822,436 | 0 | $62.24M | $54.51M | 1.74% | -$7.73M |
| Crescent Biopharma, Inc.(CBIO) | 2,748,763 | 2,748,763 | 0 | $32.60M | $50.49M | 1.61% | +$17.89M |
| Annexon, Inc.(ANNX) | 9,128,080 | 8,698,173 | -429,907 | $45.82M | $48.19M | 1.54% | +$2.36M |
| Compass Therapeutics, Inc.(CMPX) | 7,764,842 | 7,764,842 | 0 | $41.70M | $41.08M | 1.31% | -$621.2K |
| Immunocore Holdings plcADS(IMCR) | 1,488,975 | 1,294,463 | -194,512 | $50.29M | $39.03M | 1.24% | -$11.27M |
| Septerna, Inc.(SEPN) | 1,720,782 | 1,353,249 | -367,533 | $47.98M | $32.52M | 1.04% | -$15.46M |
| Sutro Biopharma, Inc.(STRO) | 0 | 1,251,788 | +1,251,788 | $0 | $31.18M | 0.99% | +$31.18M |
| Foghorn Therapeutics Inc.(FHTX) | 5,302,000 | 5,842,000 | +540,000 | $28.63M | $27.92M | 0.89% | -$706.0K |
| 4d Molecular Therapeutics In | 4,629,289 | 2,879,289 | -1,750,000 | $34.72M | $26.81M | 0.85% | -$7.91M |
| Invivyd, Inc.(IVVD) | 19,525,000 | 19,525,000 | 0 | $48.23M | $25.38M | 0.81% | -$22.84M |
| Avalo Therapeutics, Inc.(AVTX) | 1,355,257 | 1,632,845 | +277,588 | $24.61M | $24.38M | 0.78% | -$233.1K |
| Eledon Pharmaceuticals, Inc.(ELDN) | 6,293,282 | 6,293,282 | 0 | $9.50M | $19.38M | 0.62% | +$9.88M |
| Anteris Technologies Global Corp.(AVR) | 0 | 3,000,000 | +3,000,000 | $0 | $16.65M | 0.53% | +$16.65M |
| X4 Pharmaceuticals, Inc.(XFOR) | 2,233,742 | 2,233,742 | 0 | $8.93M | $9.23M | 0.29% | +$290.4K |
| Immunic, Inc.(IMUX) | 7,652,972 | 7,652,972 | 0 | $4.08M | $8.49M | 0.27% | +$4.41M |
| OnKure Therapeutics, Inc.CL A(OKUR) | 0 | 1,978,972 | +1,978,972 | $0 | $8.19M | 0.26% | +$8.19M |
| TScan Therapeutics, Inc.(TCRX) | 5,226,074 | 5,564,290 | +338,216 | $5.23M | $5.62M | 0.18% | +$393.9K |
| ImageneBio, Inc.(IMA) | 802,102 | 1,110,002 | +307,900 | $5.53M | $5.55M | 0.18% | +$15.5K |
| Tenax Therapeutics, Inc.(TENX) | 339,549 | 339,549 | 0 | $4.14M | $5.43M | 0.17% | +$1.29M |
| Molecular Partners AGADS(MOLN) | 1,353,968 | 1,353,968 | 0 | $5.82M | $5.36M | 0.17% | -$460.3K |
| Inventiva S.A.ADS(IVA) | 686,040 | 686,040 | 0 | $3.19M | $3.81M | 0.12% | +$617.4K |
| Engene Holdings IncW EXP 10 31 202 *W EXP 10/31/202 | 945,402 | 945,402 | 0 | $2.40M | $2.49M | 0.08% | +$85.1K |
| ABIVAX Société AnonymeADS(ABVX) | 508,031 | 0 | -508,031 | $68.51M | $0 | — | -$68.51M |
| Axsome Therapeutics, Inc.(AXSM) | 45,757 | 0 | -45,757 | $8.36M | $0 | — | -$8.36M |
| PepGen Inc.(PEPG) | 1,915,000 | 0 | -1,915,000 | $12.47M | $0 | — | -$12.47M |
| Repare Therapeutics Inc | 10,333,600 | 0 | -10,333,600 | $26.87M | $0 | — | -$26.87M |