Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q3 2025 ▲▼ | Q4 2025 ▲▼ | Change ▲▼ | Q3 2025 ▲▼ | Q4 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Kymera Therapeutics, Inc.(KYMR) | 5,502,710 | 5,502,710 | 0 | $311.45M | $428.17M | 14.41% | +$116.71M |
| Revolution Medicines, Inc.(RVMD) | 3,974,913 | 3,356,782 | -618,131 | $185.63M | $267.37M | 9.00% | +$81.74M |
| MoonLake ImmunotherapeuticsCL A(MLTX) | 19,751,284 | 19,751,284 | 0 | $141.62M | $260.32M | 8.76% | +$118.71M |
| Structure Therapeutics IncADS | 3,203,917 | 3,479,022 | +275,105 | $89.71M | $241.97M | 8.15% | +$152.26M |
| Olema Pharmaceuticals, Inc.(OLMA) | 5,295,893 | 5,295,893 | 0 | $51.85M | $132.40M | 4.46% | +$80.55M |
| Mirum Pharmaceuticals, Inc.(MIRM) | 1,495,290 | 1,495,290 | 0 | $109.62M | $118.11M | 3.98% | +$8.49M |
| GH Research PLC(GHRS) | 8,827,712 | 8,827,712 | 0 | $126.24M | $112.11M | 3.77% | -$14.12M |
| Xencor, Inc.(XNCR) | 2,740,141 | 7,133,720 | +4,393,579 | $32.14M | $109.22M | 3.68% | +$77.08M |
| Zymeworks Inc.(ZYME) | 3,938,641 | 3,938,641 | 0 | $67.27M | $103.70M | 3.49% | +$36.43M |
| Palvella Therapeutics, Inc.(PVLA) | 1,161,249 | 879,009 | -282,240 | $72.80M | $92.01M | 3.10% | +$19.21M |
| Kura Oncology, Inc.(KURA) | 8,617,162 | 8,617,162 | 0 | $76.26M | $89.53M | 3.01% | +$13.27M |
| Stoke Therapeutics, Inc.(STOK) | 1,657,096 | 2,265,674 | +608,578 | $38.94M | $71.91M | 2.42% | +$32.97M |
| Xoma Royalty Corporation | 2,590,303 | 2,590,303 | 0 | $99.83M | $68.88M | 2.32% | -$30.95M |
| ABIVAX Société AnonymeADS(ABVX) | 558,031 | 508,031 | -50,000 | $47.38M | $68.51M | 2.31% | +$21.13M |
| Nektar Therapeutics(NKTR) | 1,276,595 | 1,559,595 | +283,000 | $72.64M | $65.94M | 2.22% | -$6.70M |
| AC Immune SASHS(ACIU) | 19,822,436 | 19,822,436 | 0 | $57.29M | $62.24M | 2.10% | +$4.96M |
| Monte Rosa Therapeutics, Inc.(GLUE) | 5,660,132 | 3,835,886 | -1,824,246 | $41.94M | $60.15M | 2.02% | +$18.21M |
| Cullinan Therapeutics, Inc.(CGEM) | 5,750,683 | 5,750,683 | 0 | $34.10M | $59.52M | 2.00% | +$25.42M |
| Tyra Biosciences, Inc.(TYRA) | 3,649,794 | 2,127,665 | -1,522,129 | $51.06M | $55.94M | 1.88% | +$4.88M |
| Disc Medicine, Inc.(IRON) | 0 | 650,000 | +650,000 | $0 | $51.62M | 1.74% | +$51.62M |
| Immunocore Holdings plcADS(IMCR) | 1,574,288 | 1,488,975 | -85,313 | $57.19M | $50.29M | 1.69% | -$6.90M |
| Invivyd, Inc.(IVVD) | 0 | 19,525,000 | +19,525,000 | $0 | $48.23M | 1.62% | +$48.23M |
| Septerna, Inc.(SEPN) | 4,015,790 | 1,720,782 | -2,295,008 | $75.54M | $47.98M | 1.61% | -$27.56M |
| Annexon, Inc.(ANNX) | 7,000,000 | 9,128,080 | +2,128,080 | $21.35M | $45.82M | 1.54% | +$24.47M |
| Compass Therapeutics, Inc.(CMPX) | 4,750,000 | 7,764,842 | +3,014,842 | $16.63M | $41.70M | 1.40% | +$25.07M |
| 4d Molecular Therapeutics In | 4,629,289 | 4,629,289 | 0 | $40.23M | $34.72M | 1.17% | -$5.51M |
| Crescent Biopharma, Inc.(CBIO) | 1,387,863 | 2,748,763 | +1,360,900 | $16.50M | $32.60M | 1.10% | +$16.10M |
| Foghorn Therapeutics Inc.(FHTX) | 5,302,000 | 5,302,000 | 0 | $25.93M | $28.63M | 0.96% | +$2.70M |
| Repare Therapeutics Inc | 10,333,600 | 10,333,600 | 0 | $18.19M | $26.87M | 0.90% | +$8.68M |
| Avalo Therapeutics, Inc.(AVTX) | 1,355,256 | 1,355,257 | +1 | $17.23M | $24.61M | 0.83% | +$7.39M |
| PepGen Inc.(PEPG) | 1,915,000 | 1,915,000 | 0 | $8.85M | $12.47M | 0.42% | +$3.62M |
| Eledon Pharmaceuticals, Inc.(ELDN) | 6,293,282 | 6,293,282 | 0 | $16.30M | $9.50M | 0.32% | -$6.80M |
| X4 Pharmaceuticals, Inc.(XFOR) | 2,233,742 | 2,233,742 | 0 | $7.64M | $8.93M | 0.30% | +$1.30M |
| Axsome Therapeutics, Inc.(AXSM) | 486,757 | 45,757 | -441,000 | $59.12M | $8.36M | 0.28% | -$50.76M |
| Molecular Partners AGADS(MOLN) | 1,353,968 | 1,353,968 | 0 | $5.02M | $5.82M | 0.20% | +$798.8K |
| ImageneBio, Inc.(IMA) | 802,102 | 802,102 | 0 | $6.54M | $5.53M | 0.19% | -$1.00M |
| TScan Therapeutics, Inc.(TCRX) | 5,226,074 | 5,226,074 | 0 | $9.51M | $5.23M | 0.18% | -$4.29M |
| Tenax Therapeutics, Inc.(TENX) | 339,549 | 339,549 | 0 | $2.58M | $4.14M | 0.14% | +$1.56M |
| Immunic, Inc.(IMUX) | 7,652,972 | 7,652,972 | 0 | $6.75M | $4.08M | 0.14% | -$2.66M |
| Inventiva S.A.ADS(IVA) | 686,040 | 686,040 | 0 | $3.97M | $3.19M | 0.11% | -$782.1K |
| Engene Holdings IncW EXP 10 31 202 *W EXP 10/31/202 | 945,402 | 945,402 | 0 | $680.7K | $2.40M | 0.08% | +$1.72M |
| Celcuity Inc.(CELC) | 658,421 | 0 | -658,421 | $32.53M | $0 | — | -$32.53M |
| Cidara Therapeutics Inc | 1,414,165 | 0 | -1,414,165 | $135.42M | $0 | — | -$135.42M |
| Essa Pharma Inc | 11,668,473 | 0 | -11,668,473 | $2.23M | $0 | — | -$2.23M |
| Forte Biosciences Inc | 65,350 | 0 | -65,350 | $980.3K | $0 | — | -$980.3K |
| Nls Pharmaceutics Ltd | 143,676 | 0 | -143,676 | $262.9K | $0 | — | -$262.9K |
| Protagonist Therapeutics Inc | 2,560,916 | 0 | -2,560,916 | $170.12M | $0 | — | -$170.12M |
| SAB Biotherapeutics, Inc.(SABS) | 932,697 | 0 | -932,697 | $1.87M | $0 | — | -$1.87M |