Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q1 2024 ▲▼ | Q2 2024 ▲▼ | Change ▲▼ | Q1 2024 ▲▼ | Q2 2024 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Cerevel Therapeutics Hldng I | 10,794,876 | 10,794,876 | 0 | $456.30M | $441.40M | 10.65% | -$14.90M |
| Amicus Therapeutics Inc COM | 28,057,456 | 28,057,456 | 0 | $330.52M | $278.33M | 6.72% | -$52.19M |
| Arcellx Inc COMMON STOCK | 3,933,556 | 3,889,739 | -43,817 | $273.58M | $214.67M | 5.18% | -$58.90M |
| Iovance Biotherapeutics, Inc.(IOVA) | 19,272,991 | 25,933,142 | +6,660,151 | $285.63M | $207.98M | 5.02% | -$77.64M |
| Nuvalent Inc | 2,783,454 | 2,549,077 | -234,377 | $209.01M | $193.37M | 4.67% | -$15.64M |
| Rhythm Pharmaceuticals, Inc.(RYTM) | 3,268,579 | 3,446,579 | +178,000 | $141.63M | $141.52M | 3.42% | -$111.0K |
| Vaxcyte, Inc.(PCVX) | 1,932,759 | 1,862,608 | -70,151 | $132.03M | $140.65M | 3.39% | +$8.62M |
| Soleno Therapeutics Inc | 3,074,542 | 3,204,976 | +130,434 | $131.59M | $130.76M | 3.16% | -$827.4K |
| Intra-Cellular Therapies Inc | 1,055,355 | 1,716,407 | +661,052 | $73.03M | $117.56M | 2.84% | +$44.53M |
| Immatics N.V.SHS(IMTX) | 4,582,409 | 8,086,159 | +3,503,750 | $48.16M | $93.96M | 2.27% | +$45.80M |
| Neurocrine Biosciences, Inc.(NBIX) | 804,409 | 649,909 | -154,500 | $110.94M | $89.47M | 2.16% | -$21.47M |
| Apogee Therapeutics Inc | 2,060,395 | 2,105,636 | +45,241 | $136.91M | $82.86M | 2.00% | -$54.06M |
| Madrigal Pharmaceuticals, Inc.(MDGL) | 429,953 | 264,600 | -165,353 | $114.81M | $74.13M | 1.79% | -$40.68M |
| Artivion, Inc.(AORT) | 2,668,978 | 2,793,703 | +124,725 | $56.48M | $71.66M | 1.73% | +$15.18M |
| Spyre Therapeutics, Inc.(SYRE) | 2,556,679 | 3,031,018 | +474,339 | $96.97M | $71.26M | 1.72% | -$25.72M |
| Crinetics Pharmaceuticals In | 1,476,203 | 1,476,203 | 0 | $69.10M | $66.12M | 1.60% | -$2.98M |
| Evolus, Inc.(EOLS) | 5,753,798 | 5,753,798 | 0 | $80.55M | $62.43M | 1.51% | -$18.12M |
| Springworks Therapeutics Inc | 2,262,462 | 1,652,962 | -609,500 | $111.36M | $62.27M | 1.50% | -$49.09M |
| Cargo Therapeutics Inc | 3,448,004 | 3,683,004 | +235,000 | $76.96M | $60.47M | 1.46% | -$16.48M |
| Astria Therapeutics Inc | 6,485,420 | 6,485,420 | 0 | $91.25M | $59.02M | 1.42% | -$32.23M |
| Natera, Inc.(NTRA) | 757,225 | 530,000 | -227,225 | $69.26M | $57.39M | 1.39% | -$11.86M |
| Verrica Pharmaceuticals Inc.(VRCA) | 7,099,182 | 7,099,182 | 0 | $42.03M | $51.75M | 1.25% | +$9.73M |
| Biohaven Ltd.(BHVN) | 1,725,047 | 1,485,232 | -239,815 | $94.34M | $51.55M | 1.24% | -$42.79M |
| Immunovant, Inc.(IMVT) | 2,963,212 | 1,923,786 | -1,039,426 | $95.74M | $50.79M | 1.23% | -$44.95M |
| MeiraGTx Holdings plc(MGTX) | 11,331,103 | 11,331,103 | 0 | $68.72M | $47.67M | 1.15% | -$21.06M |
| Protagonist Therapeutics Inc | 994,323 | 1,268,735 | +274,412 | $28.77M | $43.96M | 1.06% | +$15.20M |
| Solid Biosciences Inc | 6,906,646 | 6,906,646 | 0 | $92.00M | $39.16M | 0.95% | -$52.84M |
| Celcuity Inc.(CELC) | 2,362,279 | 2,362,279 | 0 | $51.03M | $38.69M | 0.93% | -$12.33M |
| Medtronic plcSHS(MDT) | 1,429,563 | 490,665 | -938,898 | $124.59M | $38.62M | 0.93% | -$85.97M |
| Viking Therapeutics, Inc.(VKTX) | 994,098 | 721,377 | -272,721 | $81.52M | $38.24M | 0.92% | -$43.28M |
| Applied Therapeutics Inc | 8,005,000 | 8,005,000 | 0 | $54.43M | $37.38M | 0.90% | -$17.05M |
| Axsome Therapeutics, Inc.(AXSM) | 1,105,341 | 459,111 | -646,230 | $88.21M | $36.96M | 0.89% | -$51.25M |
| Centessa Pharmaceuticals PlcADS | 3,083,307 | 3,933,307 | +850,000 | $34.84M | $35.52M | 0.86% | +$676.4K |
| Tarsus Pharmaceuticals, Inc.(TARS) | 1,296,416 | 1,296,416 | 0 | $47.12M | $35.24M | 0.85% | -$11.89M |
| Verona Pharma PlcADS | 3,761,576 | 2,433,725 | -1,327,851 | $60.52M | $35.19M | 0.85% | -$25.33M |
| Akero Therapeutics Inc | 1,387,471 | 1,499,897 | +112,426 | $35.05M | $35.19M | 0.85% | +$140.1K |
| Edgewise Therapeutics, Inc.(EWTX) | 2,319,646 | 1,856,417 | -463,229 | $42.31M | $33.43M | 0.81% | -$8.88M |
| Acrivon Therapeutics Inc | 3,007,858 | 5,360,858 | +2,353,000 | $21.51M | $31.09M | 0.75% | +$9.59M |
| Praxis Precision Medicines, Inc.(PRAX) | 821,589 | 750,230 | -71,359 | $50.13M | $31.03M | 0.75% | -$19.10M |
| Adma Biologics Inc | 6,433,369 | 2,771,000 | -3,662,369 | $42.46M | $30.98M | 0.75% | -$11.48M |
| BridgeBio Pharma, Inc.(BBIO) | 1,412,033 | 1,215,346 | -196,687 | $43.66M | $30.78M | 0.74% | -$12.88M |
| Aldeyra Therapeutics, Inc.(ALDX) | 8,593,586 | 9,275,851 | +682,265 | $28.10M | $30.70M | 0.74% | +$2.60M |
| Nautilus Biotechnology, Inc.(NAUT) | 12,594,211 | 12,594,211 | 0 | $37.03M | $29.47M | 0.71% | -$7.56M |
| Contineum Therapeutics, Inc.CL A(CTNM) | 0 | 1,566,668 | +1,566,668 | $0 | $27.59M | 0.67% | +$27.59M |
| Intuitive Surgical, Inc.(ISRG) | 101,800 | 61,800 | -40,000 | $40.63M | $27.49M | 0.66% | -$13.14M |
| Arvinas, Inc.(ARVN) | 1,236,603 | 1,027,749 | -208,854 | $51.05M | $27.36M | 0.66% | -$23.69M |
| Rocket Pharmaceuticals, Inc.(RCKT) | 1,801,068 | 1,246,597 | -554,471 | $48.52M | $26.84M | 0.65% | -$21.68M |
| Disc Medicine, Inc.(IRON) | 939,866 | 553,437 | -386,429 | $58.52M | $24.94M | 0.60% | -$33.57M |
| LivaNova PLCSHS(LIVN) | 299,000 | 444,000 | +145,000 | $16.73M | $24.34M | 0.59% | +$7.61M |
| CG Oncology, Inc.(CGON) | 1,304,105 | 733,695 | -570,410 | $57.25M | $23.16M | 0.56% | -$34.09M |
| Xenon Pharmaceuticals Inc.(XENE) | 892,208 | 583,256 | -308,952 | $38.41M | $22.74M | 0.55% | -$15.67M |
| Ocular Therapeutix, Inc.(OCUL) | 3,324,468 | 3,324,468 | 0 | $30.25M | $22.74M | 0.55% | -$7.51M |
| PepGen Inc.(PEPG) | 1,410,438 | 1,410,438 | 0 | $20.73M | $22.51M | 0.54% | +$1.78M |
| Viridian Therapeutics, Inc.(VRDN) | 3,657,099 | 1,631,828 | -2,025,271 | $64.04M | $21.23M | 0.51% | -$42.81M |
| Orchestra BioMed Holdings, Inc.(OBIO) | 2,545,881 | 2,545,881 | 0 | $13.42M | $20.75M | 0.50% | +$7.33M |
| Merus N V | 0 | 300,000 | +300,000 | $0 | $17.75M | 0.43% | +$17.75M |
| Rapport Therapeutics, Inc.(RAPP) | 0 | 748,183 | +748,183 | $0 | $17.40M | 0.42% | +$17.40M |
| Tyra Biosciences, Inc.(TYRA) | 669,159 | 1,007,367 | +338,208 | $10.97M | $16.11M | 0.39% | +$5.13M |
| Inhibrx Biosciences, Inc.(INBX) | 0 | 1,064,026 | +1,064,026 | $0 | $15.08M | 0.36% | +$15.08M |
| Arcutis Biotherapeutics, Inc.(ARQT) | 750,000 | 1,558,500 | +808,500 | $7.43M | $14.49M | 0.35% | +$7.06M |
| Athira Pharma Inc | 5,402,964 | 5,402,964 | 0 | $14.80M | $14.32M | 0.35% | -$486.3K |
| Zymeworks Inc.(ZYME) | 1,074,807 | 1,667,711 | +592,904 | $11.31M | $14.19M | 0.34% | +$2.89M |
| Cullinan Therapeutics, Inc.(CGEM) | 0 | 749,916 | +749,916 | $0 | $13.08M | 0.32% | +$13.08M |
| PROCEPT BioRobotics Corporation(PRCT) | 210,659 | 210,659 | 0 | $10.41M | $12.87M | 0.31% | +$2.46M |
| Insmed Incorporated(INSM) | 0 | 180,000 | +180,000 | $0 | $12.06M | 0.29% | +$12.06M |
| Bicycle Therapeutics PlcADS | 0 | 572,000 | +572,000 | $0 | $11.58M | 0.28% | +$11.58M |
| ICON Public Limited CompanySHS(ICLR) | 0 | 31,250 | +31,250 | $0 | $9.80M | 0.24% | +$9.80M |
| Tempus AI, Inc.CL A(TEM) | 0 | 275,000 | +275,000 | $0 | $9.63M | 0.23% | +$9.63M |
| ArriVent BioPharma, Inc.(AVBP) | 415,000 | 415,000 | 0 | $7.41M | $7.70M | 0.19% | +$286.4K |
| Engene Holdings Inc COM | 998,888 | 800,000 | -198,888 | $16.93M | $7.54M | 0.18% | -$9.39M |
| ARS Pharmaceuticals, Inc.(SPRY) | 867,319 | 867,319 | 0 | $8.86M | $7.38M | 0.18% | -$1.48M |
| argenx SEADR(ARGX) | 0 | 15,600 | +15,600 | $0 | $6.71M | 0.16% | +$6.71M |
| Allogene Therapeutics Inc | 0 | 2,725,000 | +2,725,000 | $0 | $6.35M | 0.15% | +$6.35M |
| Veru Inc.(VERU) | 5,584,699 | 7,063,277 | +1,478,578 | $3.91M | $5.94M | 0.14% | +$2.03M |
| Kalvista Pharmaceuticals Inc | 500,000 | 500,000 | 0 | $5.93M | $5.89M | 0.14% | -$40.0K |
| Recursion Pharmaceuticals, Inc.CL A(RXRX) | 0 | 769,230 | +769,230 | $0 | $5.77M | 0.14% | +$5.77M |
| EyePoint, Inc.(EYPT) | 589,646 | 640,274 | +50,628 | $12.19M | $5.57M | 0.13% | -$6.62M |
| Helix Acquisition Corp IiCL A | 500,000 | 500,000 | 0 | $5.20M | $5.11M | 0.12% | -$90.0K |
| Mereo BioPharma Group plcADS(MREO) | 0 | 1,253,250 | +1,253,250 | $0 | $4.51M | 0.11% | +$4.51M |
| Cabaletta Bio, Inc.(CABA) | 1,716,660 | 585,045 | -1,131,615 | $29.29M | $4.38M | 0.11% | -$24.91M |
| Precision BioSciences, Inc.(DTIL) | 480,483 | 426,293 | -54,190 | $6.52M | $4.15M | 0.10% | -$2.37M |
| Skye Bioscience, Inc.(SKYE) | 0 | 500,000 | +500,000 | $0 | $4.00M | 0.10% | +$4.00M |
| Trinity Biotech plcSPONS ARD NEW(TRIB) | 1,800,000 | 1,800,000 | 0 | $3.67M | $3.83M | 0.09% | +$162.0K |
| iRhythm Holdings, Inc.(IRTC) | 245,205 | 35,205 | -210,000 | $28.44M | $3.79M | 0.09% | -$24.65M |
| Lyra Therapeutics Inc | 12,757,562 | 12,757,562 | 0 | $79.35M | $3.53M | 0.09% | -$75.82M |
| Biodesix, Inc.(BDSX) | 0 | 2,173,880 | +2,173,880 | $0 | $3.33M | 0.08% | +$3.33M |
| enVVeno Medical Corporation(NVNO) | 623,315 | 623,315 | 0 | $3.39M | $3.27M | 0.08% | -$118.4K |
| Foghorn Therapeutics Inc.(FHTX) | 0 | 544,000 | +544,000 | $0 | $3.13M | 0.08% | +$3.13M |
| Nanobiotix S.A.ADS(NBTX) | 555,066 | 555,066 | 0 | $3.61M | $2.78M | 0.07% | -$832.5K |
| Absci Corporation | 700,000 | 700,000 | 0 | $3.98M | $2.16M | 0.05% | -$1.82M |
| Spdr Ser TrS P BIOTECH ST STR SP BIOT | 0 | 22,665 | +22,665 | $0 | $2.10M | 0.05% | +$2.10M |
| X4 Pharmaceuticals, Inc.(XFOR) | 3,545,454 | 3,545,454 | 0 | $4.93M | $2.06M | 0.05% | -$2.87M |
| Forte Biosciences Inc | 3,265,359 | 3,265,359 | 0 | $2.27M | $1.75M | 0.04% | -$519.8K |
| Revance Therapeutics Inc | 600,000 | 600,000 | 0 | $2.95M | $1.54M | 0.04% | -$1.41M |
| Structure Therapeutics IncADS | 0 | 34,852 | +34,852 | $0 | $1.37M | 0.03% | +$1.37M |
| Fate Therapeutics, Inc.(FATE) | 0 | 345,575 | +345,575 | $0 | $1.13M | 0.03% | +$1.13M |
| Kyverna Therapeutics, Inc.(KYTX) | 150,000 | 150,000 | 0 | $3.73M | $1.13M | 0.03% | -$2.60M |
| Eagle Pharmaceuticals Inc | 0 | 173,365 | +173,365 | $0 | $970.8K | 0.02% | +$970.8K |
| Vbi Vaccines Inc Cda | 1,261,710 | 1,261,710 | 0 | $757.0K | $832.7K | 0.02% | +$75.7K |
| Tactile Systems Technology, Inc.(TCMD) | 903,085 | 62,639 | -840,446 | $14.68M | $747.9K | 0.02% | -$13.93M |