Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q4 2025 ▲▼ | Q1 2026 ▲▼ | Change ▲▼ | Q4 2025 ▲▼ | Q1 2026 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Aurinia Pharmaceuticals Inc.(AUPH) | 11,329,500 | 12,229,500 | +900,000 | $180.71M | $181.24M | 9.20% | +$535.7K |
| Celcuity Inc.(CELC) | 1,050,000 | 1,050,000 | 0 | $104.73M | $119.85M | 6.09% | +$15.12M |
| Mirum Pharmaceuticals, Inc.(MIRM) | 1,236,027 | 1,236,027 | 0 | $97.63M | $114.18M | 5.80% | +$16.55M |
| Lakefront Biotherapeutics NVADR(LKFT) | 3,921,219 | 3,785,991 | -135,228 | $128.22M | $113.58M | 5.77% | -$14.64M |
| State Street SPDR S&P 500 ETF TrustTR UNIT(SPY) | 30,000 | 168,000 | +138,000 | $20.46M | $109.26M | 5.55% | +$88.80M |
| Kiniksa Pharmaceuticals International, plcCL A(KNSA) | 2,259,889 | 2,259,889 | 0 | $93.22M | $108.81M | 5.53% | +$15.59M |
| Capricor Therapeutics, Inc.(CAPR) | 1,700,000 | 3,399,900 | +1,699,900 | $49.06M | $103.36M | 5.25% | +$54.29M |
| PTC Therapeutics, Inc.(PTCT) | 1,500,000 | 1,500,000 | 0 | $113.94M | $102.19M | 5.19% | -$11.74M |
| Spyre Therapeutics, Inc.(SYRE) | 1,892,200 | 1,892,200 | 0 | $61.99M | $95.44M | 4.85% | +$33.45M |
| Kalvista Pharmaceuticals Inc | 4,573,530 | 4,573,530 | 0 | $73.86M | $92.07M | 4.68% | +$18.20M |
| Compass Therapeutics, Inc.(CMPX) | 16,790,809 | 16,790,809 | 0 | $90.17M | $88.82M | 4.51% | -$1.34M |
| Tarsus Pharmaceuticals, Inc.(TARS) | 1,188,624 | 1,188,624 | 0 | $97.32M | $83.38M | 4.23% | -$13.94M |
| Immunocore Holdings plcADS(IMCR) | 2,628,538 | 2,649,368 | +20,830 | $91.24M | $79.88M | 4.06% | -$11.36M |
| Anaptysbio Inc | 1,332,087 | 1,330,879 | -1,208 | $64.58M | $73.81M | 3.75% | +$9.23M |
| Corcept Therapeutics Incorporated(CORT) | 156,764 | 1,500,000 | +1,343,236 | $5.46M | $60.47M | 3.07% | +$55.01M |
| ANI Pharmaceuticals, Inc.(ANIP) | 481,437 | 707,500 | +226,063 | $38.00M | $54.41M | 2.76% | +$16.40M |
| Insmed Incorporated(INSM) | 60,000 | 260,000 | +200,000 | $10.44M | $42.52M | 2.16% | +$32.07M |
| BioNTech SEADS(BNTX) | 470,000 | 470,000 | 0 | $44.74M | $41.77M | 2.12% | -$2.97M |
| Viridian Therapeutics, Inc.(VRDN) | 1,792,626 | 1,792,626 | 0 | $55.79M | $35.06M | 1.78% | -$20.72M |
| Atea Pharmaceuticals, Inc.(AVIR) | 4,814,700 | 4,814,700 | 0 | $17.19M | $25.90M | 1.32% | +$8.71M |
| Precigen, Inc.(PGEN) | 5,617,500 | 6,417,500 | +800,000 | $23.48M | $24.84M | 1.26% | +$1.35M |
| Dianthus Therapeutics, Inc.(DNTH) | 264,692 | 264,692 | 0 | $10.91M | $22.21M | 1.13% | +$11.30M |
| COMPASS Pathways plcADS(CMPS) | 0 | 4,002,200 | +4,002,200 | $0 | $22.13M | 1.12% | +$22.13M |
| Crescent Biopharma, Inc.(CBIO) | 872,398 | 1,160,000 | +287,602 | $10.35M | $21.31M | 1.08% | +$10.96M |
| Stoke Therapeutics, Inc.(STOK) | 500,000 | 500,000 | 0 | $15.87M | $16.28M | 0.83% | +$410.0K |
| Viking Therapeutics, Inc.(VKTX) | 500,000 | 500,000 | 0 | $17.59M | $16.27M | 0.83% | -$1.32M |
| IDEAYA Biosciences, Inc.(IDYA) | 450,000 | 450,000 | 0 | $15.56M | $14.99M | 0.76% | -$562.5K |
| Nuvation Bio Inc.CL A(NUVB) | 3,857,457 | 3,149,557 | -707,900 | $34.56M | $13.51M | 0.69% | -$21.05M |
| Pliant Therapeutics, Inc.(PLRX) | 6,143,132 | 6,143,132 | 0 | $7.49M | $7.74M | 0.39% | +$245.7K |
| Journey Medical Corporation(DERM) | 1,854,596 | 1,610,000 | -244,596 | $14.30M | $7.55M | 0.38% | -$6.75M |
| Janux Therapeutics, Inc.(JANX) | 0 | 500,000 | +500,000 | $0 | $6.95M | 0.35% | +$6.95M |
| Biogen Inc.(BIIB) | 35,000 | 35,000 | 0 | $6.16M | $6.42M | 0.33% | +$256.9K |
| UroGen Pharma Ltd.(URGN) | 350,000 | 350,000 | 0 | $8.20M | $6.29M | 0.32% | -$1.90M |
| Arvinas, Inc.(ARVN) | 569,698 | 538,658 | -31,040 | $6.76M | $5.71M | 0.29% | -$1.05M |
| PMV Pharmaceuticals, Inc.(PMVP) | 4,940,000 | 4,245,085 | -694,915 | $6.17M | $5.26M | 0.27% | -$911.1K |
| Moderna, Inc.(MRNA) | 692,820 | 100,000 | -592,820 | $20.43M | $5.08M | 0.26% | -$15.35M |
| Heron Therapeutics, Inc.(HRTX) | 6,250,000 | 6,250,000 | 0 | $8.13M | $5.00M | 0.25% | -$3.12M |
| Kezar Life Sciences Inc COM NEW | 664,314 | 664,314 | 0 | $4.18M | $4.93M | 0.25% | +$750.7K |
| Wave Life Sciences, Inc.SHS(WVE) | 600,000 | 600,000 | 0 | $10.20M | $4.35M | 0.22% | -$5.85M |
| LENZ Therapeutics, Inc.(LENZ) | 865,169 | 451,114 | -414,055 | $13.84M | $4.13M | 0.21% | -$9.72M |
| Agios Pharmaceuticals, Inc.(AGIO) | 0 | 100,000 | +100,000 | $0 | $3.38M | 0.17% | +$3.38M |
| Erasca, Inc.(ERAS) | 900,000 | 200,000 | -700,000 | $3.35M | $3.24M | 0.16% | -$112.0K |
| Coherus Oncology, Inc.(CHRS) | 2,724,509 | 1,886,748 | -837,761 | $3.87M | $3.19M | 0.16% | -$680.2K |
| Nkarta, Inc.(NKTX) | 1,480,823 | 1,480,823 | 0 | $2.74M | $3.12M | 0.16% | +$385.0K |
| Altimmune, Inc.(ALT) | 2,131,307 | 666,022 | -1,465,285 | $7.69M | $2.05M | 0.10% | -$5.64M |
| Evolus, Inc.(EOLS) | 1,245,692 | 483,021 | -762,671 | $8.28M | $1.99M | 0.10% | -$6.30M |
| Abeona Therapeutics Inc.(ABEO) | 1,000,000 | 400,000 | -600,000 | $5.27M | $1.79M | 0.09% | -$3.48M |
| Fate Therapeutics, Inc.(FATE) | 1,167,773 | 1,167,773 | 0 | $1.15M | $1.40M | 0.07% | +$253.9K |
| Neumora Therapeutics, Inc.(NMRA) | 967,235 | 439,878 | -527,357 | $1.73M | $857.8K | 0.04% | -$873.6K |
| Lexicon Pharmaceuticals, Inc.(LXRX) | 0 | 399,700 | +399,700 | $0 | $623.5K | 0.03% | +$623.5K |
| Rocket Pharmaceuticals, Inc.(RCKT) | 100,000 | 100,000 | 0 | $351.0K | $358.0K | 0.02% | +$7.0K |
| Acadia Pharmaceuticals Inc | 300,000 | 0 | -300,000 | $8.01M | $0 | — | -$8.01M |
| Adicet Bio Inc | 6,158 | 0 | -6,158 | $51.9K | $0 | — | -$51.9K |
| Alexandria Real Estate Eq In | 40,000 | 0 | -40,000 | $1.96M | $0 | — | -$1.96M |
| Avidity Biosciences Inc | 900,000 | 0 | -900,000 | $64.92M | $0 | — | -$64.92M |
| BioCryst Pharmaceuticals, Inc.(BCRX) | 800,000 | 0 | -800,000 | $6.24M | $0 | — | -$6.24M |
| Biohaven Ltd.(BHVN) | 140,000 | 0 | -140,000 | $1.58M | $0 | — | -$1.58M |
| Bristol-Myers Squibb Company(BMY) | 200,000 | 0 | -200,000 | $10.79M | $0 | — | -$10.79M |
| Filana Therapeutics, Inc.(FLNA) | 7,073 | 0 | -7,073 | $14.0K | $0 | — | -$14.0K |
| Dynavax Technologies Corp | 556,359 | 0 | -556,359 | $8.56M | $0 | — | -$8.56M |
| GSK plcADR(GSK) | 300,000 | 0 | -300,000 | $14.71M | $0 | — | -$14.71M |
| Harmony Biosciences Holdings, Inc.(HRMY) | 290,292 | 0 | -290,292 | $10.86M | $0 | — | -$10.86M |
| ImmunityBio, Inc.(IBRX) | 2,333,333 | 0 | -2,333,333 | $4.62M | $0 | — | -$4.62M |
| Meta Platforms, Inc.CL A(META) | 23,331 | 0 | -23,331 | $15.40M | $0 | — | -$15.40M |
| Nuvalent Inc | 21,880 | 0 | -21,880 | $2.20M | $0 | — | -$2.20M |
| NVIDIA Corporation(NVDA) | 127,788 | 0 | -127,788 | $23.83M | $0 | — | -$23.83M |
| Regeneron Pharmaceuticals, Inc.(REGN) | 8,000 | 0 | -8,000 | $6.17M | $0 | — | -$6.17M |
| Revolution Medicines, Inc.(RVMD) | 15,640 | 0 | -15,640 | $1.25M | $0 | — | -$1.25M |
| Sarepta Therapeutics, Inc.(SRPT) | 349,220 | 0 | -349,220 | $7.52M | $0 | — | -$7.52M |
| Sutro Biopharma, Inc.(STRO) | 139,617 | 0 | -139,617 | $1.62M | $0 | — | -$1.62M |
| Teladoc Health, Inc.(TDOC) | 1,400,000 | 0 | -1,400,000 | $9.80M | $0 | — | -$9.80M |
| Theravance Biopharma Inc | 351,252 | 0 | -351,252 | $6.57M | $0 | — | -$6.57M |
| Travere Therapeutics, Inc.(TVTX) | 700,000 | 0 | -700,000 | $26.75M | $0 | — | -$26.75M |
| TScan Therapeutics, Inc.(TCRX) | 46,131 | 0 | -46,131 | $46.1K | $0 | — | -$46.1K |
| Vaxcyte, Inc.(PCVX) | 275,000 | 0 | -275,000 | $12.69M | $0 | — | -$12.69M |
| Ventyx Biosciences Inc | 2,814,000 | 0 | -2,814,000 | $25.41M | $0 | — | -$25.41M |
| Verastem, Inc.(VSTM) | 1,069,810 | 0 | -1,069,810 | $8.26M | $0 | — | -$8.26M |
| Vertex Pharmaceuticals Incorporated(VRTX) | 80,000 | 0 | -80,000 | $36.27M | $0 | — | -$36.27M |
| Zymeworks Inc.(ZYME) | 34,631 | 0 | -34,631 | $911.8K | $0 | — | -$911.8K |