Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q1 2025 ▲▼ | Q2 2025 ▲▼ | Change ▲▼ | Q1 2025 ▲▼ | Q2 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| VERA THERAPEUTICS INC CL A(VERA) | 150,000 | 1,350,000 | +1,200,000 | 3,603 | 31,806 | 1.61% | +28,203 |
| MERUS N V | 100,000 | 600,000 | +500,000 | 4,209 | 31,560 | 1.60% | +27,351 |
| METTLER-TOLEDO INTERNATIONAL(MTD) | 0 | 19,500 | +19,500 | 0 | 22,907 | 1.16% | +22,907 |
| ITEOS THERAPEUTICS INC | 2,689,200 | 3,826,692 | +1,137,492 | 16,055 | 38,152 | 1.93% | +22,098 |
| BOEING CO(BA) | 6,068 | 105,662 | +99,594 | 1,035 | 22,139 | 1.12% | +21,104 |
| CYTOMX THERAPEUTICS INC(CTMX) | 6,717,825 | 11,065,662 | +4,347,837 | 4,271 | 25,119 | 1.27% | +20,848 |
| KINIKSA PHARMACEUTICALS INTL(KNSA) | 2,118,579 | 2,328,609 | +210,030 | 47,054 | 64,433 | 3.26% | +17,379 |
| SPYRE THERAPEUTICS INC(SYRE) | 2,050,000 | 3,200,000 | +1,150,000 | 33,077 | 47,904 | 2.42% | +14,827 |
| COMPASS THERAPEUTICS INC(CMPX) | 11,052,632 | 13,496,208 | +2,443,576 | 21,000 | 35,090 | 1.77% | +14,090 |
| UROGEN PHARMA LTD(URGN) | 0 | 1,000,000 | +1,000,000 | 0 | 13,700 | 0.69% | +13,700 |
| INSMED INC(INSM) | 100,000 | 200,000 | +100,000 | 7,629 | 20,128 | 1.02% | +12,499 |
| GALAPAGOS NV(LKFT) | 3,961,797 | 3,990,111 | +28,314 | 99,520 | 111,683 | 5.65% | +12,163 |
| TRAVERE THERAPEUTICS INC(TVTX) | 0 | 700,000 | +700,000 | 0 | 10,360 | 0.52% | +10,360 |
| IMMUNOCORE HLDGS PLC(IMCR) | 1,915,708 | 2,105,608 | +189,900 | 56,839 | 66,074 | 3.34% | +9,235 |
| GENEDX HOLDINGS CORP(WGS) | 0 | 100,000 | +100,000 | 0 | 9,231 | 0.47% | +9,231 |
| ELI LILLY & CO(LLY) | 0 | 10,000 | +10,000 | 0 | 7,795 | 0.39% | +7,795 |
| KEROS THERAPEUTICS INC(KROS) | 1,100,000 | 1,418,984 | +318,984 | 11,209 | 18,943 | 0.96% | +7,734 |
| ACADIA PHARMACEUTICALS INC | 1,500,000 | 1,500,000 | 0 | 24,915 | 32,355 | 1.64% | +7,440 |
| SAREPTA THERAPEUTICS INC(SRPT) | 0 | 420,300 | +420,300 | 0 | 7,187 | 0.36% | +7,187 |
| MIRUM PHARMACEUTICALS INC(MIRM) | 1,237,107 | 1,236,027 | -1,080 | 55,732 | 62,901 | 3.18% | +7,170 |
| RELAY THERAPEUTICS INC(RLAY) | 8,068,058 | 8,068,058 | 0 | 21,138 | 27,915 | 1.41% | +6,777 |
| LENZ THERAPEUTICS INC(LENZ) | 766,940 | 897,616 | +130,676 | 19,718 | 26,309 | 1.33% | +6,591 |
| IDEXX LABS INC(IDXX) | 5,000 | 16,000 | +11,000 | 2,100 | 8,581 | 0.43% | +6,482 |
| ALUMIS INC | 0 | 1,996,797 | +1,996,797 | 0 | 5,990 | 0.30% | +5,990 |
| SUMMIT THERAPEUTICS INC(SMMT) | 0 | 250,000 | +250,000 | 0 | 5,320 | 0.27% | +5,320 |
| NVIDIA CORPORATION(NVDA) | 142,569 | 130,509 | -12,060 | 15,452 | 20,619 | 1.04% | +5,168 |
| BAUSCH HEALTH COS INC | 0 | 736,827 | +736,827 | 0 | 4,907 | 0.25% | +4,907 |
| VERTEX PHARMACEUTICALS INC(VRTX) | 0 | 10,000 | +10,000 | 0 | 4,452 | 0.23% | +4,452 |
| AURINIA PHARMACEUTICALS INC(AUPH) | 10,029,500 | 10,029,500 | 0 | 80,637 | 84,950 | 4.29% | +4,313 |
| BIONTECH SE(BNTX) | 270,000 | 270,000 | 0 | 24,586 | 28,747 | 1.45% | +4,161 |
| CYBIN INC(HELP) | 1,830,097 | 1,830,097 | 0 | 11,603 | 15,355 | 0.78% | +3,752 |
| META PLATFORMS INC(META) | 27,575 | 26,008 | -1,567 | 15,893 | 19,196 | 0.97% | +3,303 |
| VIKING THERAPEUTICS INC(VKTX) | 270,000 | 370,000 | +100,000 | 6,521 | 9,805 | 0.50% | +3,285 |
| ATEA PHARMACEUTICALS INC(AVIR) | 4,800,000 | 4,889,200 | +89,200 | 14,352 | 17,601 | 0.89% | +3,249 |
| ABCELLERA BIOLOGICS INC(ABCL) | 2,600,000 | 2,600,000 | 0 | 5,798 | 8,918 | 0.45% | +3,120 |
| VENTYX BIOSCIENCES INC | 3,100,000 | 3,100,000 | 0 | 3,565 | 6,634 | 0.34% | +3,069 |
| ELANCO ANIMAL HEALTH INC(ELAN) | 800,100 | 800,100 | 0 | 8,401 | 11,425 | 0.58% | +3,024 |
| METSERA INC | 0 | 100,000 | +100,000 | 0 | 2,845 | 0.14% | +2,845 |
| PTC THERAPEUTICS INC(PTCT) | 1,000,000 | 1,100,000 | +100,000 | 50,960 | 53,724 | 2.72% | +2,764 |
| HILLEVAX INC | 4,920,000 | 4,920,000 | 0 | 7,134 | 9,791 | 0.49% | +2,657 |
| BEAM THERAPEUTICS INC(BEAM) | 50,000 | 205,000 | +155,000 | 977 | 3,487 | 0.18% | +2,511 |
| JOURNEY MED CORP(DERM) | 1,854,596 | 1,854,596 | 0 | 10,942 | 13,316 | 0.67% | +2,374 |
| STOKE THERAPEUTICS INC(STOK) | 500,000 | 500,000 | 0 | 3,325 | 5,675 | 0.29% | +2,350 |
| CG ONCOLOGY INC(CGON) | 0 | 87,500 | +87,500 | 0 | 2,275 | 0.11% | +2,275 |
| NEUROCRINE BIOSCIENCES INC(NBIX) | 150,000 | 150,000 | 0 | 16,590 | 18,854 | 0.95% | +2,264 |
| AVADEL PHARMACEUTICALS PLC | 2,097,500 | 2,097,500 | 0 | 16,423 | 18,563 | 0.94% | +2,139 |
| VIRIDIAN THERAPEUTICS INC(VRDN) | 2,792,925 | 2,842,925 | +50,000 | 37,649 | 39,744 | 2.01% | +2,095 |
| TAYSHA GENE THERAPIES INC(TSHA) | 0 | 900,000 | +900,000 | 0 | 2,079 | 0.11% | +2,079 |
| BLACK DIAMOND THERAPEUTICS I | 2,070,209 | 2,070,209 | 0 | 3,209 | 5,134 | 0.26% | +1,925 |
| THIRD HARMONIC BIO INC | 929,727 | 929,727 | 0 | 3,226 | 5,048 | 0.26% | +1,822 |
| SUTRO BIOPHARMA INC(STRO) | 200,000 | 2,561,586 | +2,361,586 | 130 | 1,829 | 0.09% | +1,699 |
| PYXIS ONCOLOGY INC(PYXS) | 1,100,000 | 2,500,000 | +1,400,000 | 1,078 | 2,750 | 0.14% | +1,672 |
| MIND MEDICINE MINDMED INC | 400,200 | 600,200 | +200,000 | 2,341 | 3,895 | 0.20% | +1,554 |
| REPLIMUNE GROUP INC(REPL) | 2,900,000 | 3,200,000 | +300,000 | 28,275 | 29,728 | 1.50% | +1,453 |
| IONIS PHARMACEUTICALS INC(IONS) | 150,000 | 150,000 | 0 | 4,526 | 5,927 | 0.30% | +1,401 |
| ATYR PHARMA INC | 671,134 | 671,134 | 0 | 2,027 | 3,403 | 0.17% | +1,376 |
| LEGEND BIOTECH CORP(LEGN) | 830,000 | 830,000 | 0 | 28,162 | 29,457 | 1.49% | +1,295 |
| APOGEE THERAPEUTICS INC(APGE) | 200,000 | 200,000 | 0 | 7,472 | 8,686 | 0.44% | +1,214 |
| BIOCRYST PHARMACEUTICALS INC(BCRX) | 800,000 | 800,000 | 0 | 6,000 | 7,168 | 0.36% | +1,168 |
| TELADOC HEALTH INC(TDOC) | 1,400,000 | 1,400,000 | 0 | 11,144 | 12,194 | 0.62% | +1,050 |
| BOLT BIOTHERAPEUTICS INC | 0 | 166,879 | +166,879 | 0 | 963 | 0.05% | +963 |
| TEMPEST THERAPEUTICS INC(TPST) | 0 | 138,962 | +138,962 | 0 | 945 | 0.05% | +945 |
| ANAPTYSBIO INC | 1,545,153 | 1,330,879 | -214,274 | 28,724 | 29,546 | 1.49% | +821 |
| CRESCENT BIOPHARMA INC.(CBIO) | 0 | 50,152 | +50,152 | 0 | 809 | 0.04% | +809 |
| NUVATION BIO INC(NUVB) | 3,900,000 | 3,900,000 | 0 | 6,864 | 7,605 | 0.38% | +741 |
| ZYMEWORKS INC(ZYME) | 1,100,000 | 1,100,000 | 0 | 13,101 | 13,805 | 0.70% | +704 |
| SEER INC(SEER) | 1,294,423 | 1,344,423 | +50,000 | 2,188 | 2,877 | 0.15% | +689 |
| SOLENO THERAPEUTICS INC | 50,000 | 50,000 | 0 | 3,573 | 4,189 | 0.21% | +617 |
| FATE THERAPEUTICS INC(FATE) | 1,867,773 | 1,867,773 | 0 | 1,476 | 2,092 | 0.11% | +616 |
| BIOAGE LABS INC(BIOA) | 1,600,000 | 1,600,000 | 0 | 6,016 | 6,608 | 0.33% | +592 |
| JANUX THERAPEUTICS INC(JANX) | 150,000 | 200,000 | +50,000 | 4,050 | 4,620 | 0.23% | +570 |
| THERAVANCE BIOPHARMA INC(TBPH) | 262,896 | 264,308 | +1,412 | 2,348 | 2,915 | 0.15% | +568 |
| ESSA PHARMA INC | 4,300,000 | 4,300,000 | 0 | 6,794 | 7,310 | 0.37% | +516 |
| GE VERNOVA INC(GEV) | 2,593 | 2,421 | -172 | 792 | 1,281 | 0.06% | +489 |
| OPTIMIZERX CORP(OPRX) | 100,000 | 100,000 | 0 | 866 | 1,350 | 0.07% | +484 |
| ARVINAS INC(ARVN) | 1,393,800 | 1,393,800 | 0 | 9,784 | 10,258 | 0.52% | +474 |
| TECTONIC THERAPEUTIC INC(TECX) | 179,166 | 179,166 | 0 | 3,173 | 3,560 | 0.18% | +387 |
| VANDA PHARMACEUTICALS INC(VNDA) | 2,353,307 | 2,353,307 | 0 | 10,802 | 11,108 | 0.56% | +306 |
| AMYLYX PHARMACEUTICALS INC(AMLX) | 100,000 | 100,000 | 0 | 354 | 641 | 0.03% | +287 |
| ERASCA INC(ERAS) | 1,190,012 | 1,502,915 | +312,903 | 1,630 | 1,909 | 0.10% | +278 |
| NUVALENT INC | 50,000 | 50,000 | 0 | 3,546 | 3,815 | 0.19% | +269 |
| ENANTA PHARMACEUTICALS INC(ENTA) | 126,655 | 126,655 | 0 | 699 | 958 | 0.05% | +258 |
| NETFLIX INC(NFLX) | 1,301 | 1,089 | -212 | 1,213 | 1,458 | 0.07% | +245 |
| GENMAB A/S(GMAB) | 200,000 | 200,000 | 0 | 3,916 | 4,132 | 0.21% | +216 |
| SPRINGWORKS THERAPEUTICS INC | 74,265 | 74,265 | 0 | 3,277 | 3,490 | 0.18% | +212 |
| CORBUS PHARMACEUTICALS HLDGS(CRBP) | 127,520 | 127,520 | 0 | 677 | 880 | 0.04% | +203 |
| CAREDX INC(CDNA) | 100,000 | 100,000 | 0 | 1,775 | 1,954 | 0.10% | +179 |
| ULTA BEAUTY INC(ULTA) | 2,606 | 2,410 | -196 | 955 | 1,127 | 0.06% | +172 |
| FENNEC PHARMACEUTICALS INC(FENC) | 0 | 20,527 | +20,527 | 0 | 170 | 0.01% | +170 |
| SERES THERAPEUTICS INC(MCRB) | 0 | 13,921 | +13,921 | 0 | 155 | 0.01% | +155 |
| CARGO THERAPEUTICS INC | 3,059,630 | 3,059,630 | 0 | 12,453 | 12,606 | 0.64% | +153 |
| GE AEROSPACE(GE) | 5,675 | 4,986 | -689 | 1,136 | 1,283 | 0.06% | +148 |
| REVOLUTION MEDICINES INC(RVMD) | 100,000 | 100,000 | 0 | 3,536 | 3,679 | 0.19% | +143 |
| CASSAVA SCIENCES INC COMMON STOCK(FLNA) | 200,000 | 239,820 | +39,820 | 300 | 434 | 0.02% | +134 |
| HEWLETT PACKARD ENTERPRISE C(HPE) | 44,547 | 40,002 | -4,545 | 687 | 818 | 0.04% | +131 |
| DIANTHUS THERAPEUTICS INC(DNTH) | 264,692 | 264,692 | 0 | 4,802 | 4,931 | 0.25% | +130 |
| METAGENOMI INC(MGX) | 134,978 | 200,000 | +65,022 | 184 | 296 | 0.01% | +112 |
| PUMA BIOTECHNOLOGY INC(PBYI) | 200,000 | 200,000 | 0 | 592 | 686 | 0.03% | +94 |
| KODIAK SCIENCES INC(KOD) | 100,000 | 100,000 | 0 | 281 | 373 | 0.02% | +93 |
| CENTURY THERAPEUTICS INC(IPSC) | 900,000 | 900,000 | 0 | 428 | 503 | 0.03% | +74 |