Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q1 2026 ▲▼ | Q2 2026 ▲▼ | Change ▲▼ | Q1 2026 ▲▼ | Q2 2026 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Incyte Corporation(INCY) | 30,744,412 | 30,762,330 | +17,918 | $2.89B | $3.49B | 17.48% | +$593.55M |
| BeOne Medicines AGADS(ONC) | 8,799,053 | 8,801,567 | +2,514 | $2.61B | $2.51B | 12.57% | -$104.87M |
| Revolution Medicines, Inc.(RVMD) | 9,555,357 | 11,443,357 | +1,888,000 | $929.26M | $2.14B | 10.74% | +$1.21B |
| Madrigal Pharmaceuticals, Inc.(MDGL) | 2,141,701 | 2,143,131 | +1,430 | $1.12B | $1.15B | 5.77% | +$29.64M |
| ACADIA Pharmaceuticals Inc. | 42,896,690 | 42,912,904 | +16,214 | $954.88M | $1.09B | 5.44% | +$130.82M |
| Kymera Therapeutics, Inc.(KYMR) | 8,657,242 | 8,657,242 | 0 | $721.06M | $992.73M | 4.97% | +$271.66M |
| Insmed Incorporated(INSM) | 7,421,111 | 8,796,111 | +1,375,000 | $1.21B | $937.84M | 4.70% | -$275.66M |
| Celcuity Inc.(CELC) | 7,915,792 | 7,915,792 | 0 | $903.51M | $828.15M | 4.15% | -$75.36M |
| Kodiak Sciences Inc.(KOD) | 19,919,186 | 19,919,186 | 0 | $759.32M | $776.05M | 3.89% | +$16.73M |
| Rhythm Pharmaceuticals, Inc.(RYTM) | 5,604,483 | 5,604,483 | 0 | $487.42M | $622.27M | 3.12% | +$134.84M |
| Praxis Precision Medicines, Inc.(PRAX) | 1,753,198 | 1,753,198 | 0 | $564.86M | $586.95M | 2.94% | +$22.09M |
| Alkermes plcSHS(ALKS) | 10,012,267 | 10,012,267 | 0 | $354.03M | $524.59M | 2.63% | +$170.56M |
| Summit Therapeutics Inc.(SMMT) | 36,391,063 | 32,786,348 | -3,604,715 | $689.97M | $477.70M | 2.39% | -$212.28M |
| GRAIL, Inc.(GRAL) | 4,028,614 | 4,028,614 | 0 | $208.20M | $275.03M | 1.38% | +$66.83M |
| AbCellera Biologics Inc.(ABCL) | 30,275,938 | 33,012,138 | +2,736,200 | $105.66M | $259.15M | 1.30% | +$153.48M |
| Immunovant, Inc.(IMVT) | 5,457,881 | 5,435,220 | -22,661 | $135.57M | $209.42M | 1.05% | +$73.85M |
| IDEAYA Biosciences, Inc.(IDYA) | 3,946,515 | 5,010,030 | +1,063,515 | $131.50M | $186.72M | 0.94% | +$55.23M |
| Kiniksa Pharmaceuticals International, plcCL A(KNSA) | 2,826,246 | 2,834,643 | +8,397 | $136.08M | $181.28M | 0.91% | +$45.19M |
| Roivant Sciences Ltd.SHS(ROIV) | 4,867,723 | 4,716,831 | -150,892 | $134.84M | $166.93M | 0.84% | +$32.09M |
| Arrowhead Pharmaceuticals, Inc.(ARWR) | 1,992,783 | 1,992,783 | 0 | $124.95M | $162.43M | 0.81% | +$37.48M |
| Ionis Pharmaceuticals, Inc.(IONS) | 2,047,727 | 2,047,727 | 0 | $153.76M | $162.36M | 0.81% | +$8.60M |
| Edgewise Therapeutics, Inc.(EWTX) | 6,575,940 | 3,701,719 | -2,874,221 | $207.14M | $150.40M | 0.75% | -$56.74M |
| Replimune Group, Inc.(REPL) | 11,045,336 | 11,045,336 | 0 | $84.50M | $122.27M | 0.61% | +$37.78M |
| Nurix Therapeutics, Inc.(NRIX) | 4,658,556 | 4,658,556 | 0 | $72.21M | $113.02M | 0.57% | +$40.81M |
| Stoke Therapeutics, Inc.(STOK) | 3,336,697 | 3,336,697 | 0 | $108.64M | $109.18M | 0.55% | +$533.9K |
| Monte Rosa Therapeutics, Inc.(GLUE) | 4,345,736 | 4,345,736 | 0 | $71.49M | $105.17M | 0.53% | +$33.68M |
| Immatics N.V.SHS(IMTX) | 10,916,693 | 9,508,565 | -1,408,128 | $107.42M | $96.32M | 0.48% | -$11.10M |
| Denali Therapeutics Inc.(DNLI) | 3,731,695 | 3,734,336 | +2,641 | $71.65M | $96.05M | 0.48% | +$24.40M |
| Crinetics Pharmaceuticals, Inc. | 2,351,465 | 2,351,465 | 0 | $85.41M | $87.99M | 0.44% | +$2.59M |
| Dianthus Therapeutics, Inc.(DNTH) | 852,164 | 852,164 | 0 | $71.51M | $83.07M | 0.42% | +$11.56M |
| Structure Therapeutics Inc.ADS | 1,432,529 | 1,432,529 | 0 | $69.05M | $76.88M | 0.39% | +$7.84M |
| Celcuity Inc.NOTE 2 75 8 1 2031(CELC) | 30,750,000 | 0 | -30,750,000 | $74.87M | $69.16M | 0.35% | -$5.71M |
| Rapport Therapeutics, Inc.(RAPP) | 1,547,090 | 1,547,090 | 0 | $48.41M | $64.47M | 0.32% | +$16.06M |
| Alumis Inc. | 2,012,500 | 2,012,500 | 0 | $44.34M | $56.63M | 0.28% | +$12.30M |
| Prelude Therapeutics Incorporated(PRLD) | 10,123,824 | 10,123,824 | 0 | $34.62M | $53.96M | 0.27% | +$19.34M |
| Relay Therapeutics, Inc.(RLAY) | 1,160,117 | 2,826,783 | +1,666,666 | $11.54M | $52.89M | 0.27% | +$41.35M |
| Mirum Pharmaceuticals, Inc.(MIRM) | 445,975 | 445,975 | 0 | $41.20M | $52.21M | 0.26% | +$11.01M |
| Bicycle Therapeutics plcADS | 10,885,357 | 10,885,357 | 0 | $50.51M | $46.15M | 0.23% | -$4.35M |
| Enliven Therapeutics, Inc. | 905,191 | 905,191 | 0 | $35.48M | $45.94M | 0.23% | +$10.45M |
| Celldex Therapeutics, Inc.(CLDX) | 665,370 | 1,182,611 | +517,241 | $21.11M | $44.00M | 0.22% | +$22.90M |
| Viridian Therapeutics, Inc.(VRDN) | 1,971,678 | 2,383,025 | +411,347 | $38.57M | $43.78M | 0.22% | +$5.21M |
| Design Therapeutics, Inc.(DSGN) | 2,585,978 | 2,678,430 | +92,452 | $27.51M | $38.76M | 0.19% | +$11.24M |
| Entrada Therapeutics, Inc.(TRDA) | 5,072,730 | 5,072,730 | 0 | $64.02M | $37.34M | 0.19% | -$26.68M |
| Faeth Therapeutics, Inc.(FTH) | 0 | 1,286,411 | +1,286,411 | $0 | $32.16M | 0.16% | +$32.16M |
| Aktis Oncology, Inc.(AKTS) | 996,351 | 996,351 | 0 | $17.82M | $32.11M | 0.16% | +$14.29M |
| Neurogene Inc.(NGNE) | 991,691 | 991,691 | 0 | $19.99M | $31.19M | 0.16% | +$11.20M |
| Jade Biosciences, Inc. | 1,641,137 | 1,230,426 | -410,711 | $23.06M | $27.34M | 0.14% | +$4.28M |
| Taysha Gene Therapies, Inc.(TSHA) | 4,004,756 | 4,004,756 | 0 | $17.90M | $27.27M | 0.14% | +$9.37M |
| Arcus Biosciences, Inc.(RCUS) | 415,621 | 844,816 | +429,195 | $8.98M | $26.05M | 0.13% | +$17.07M |
| Disc Medicine, Inc.(IRON) | 349,657 | 349,657 | 0 | $22.36M | $25.57M | 0.13% | +$3.22M |
| Absci Corporation | 2,134,803 | 2,134,803 | 0 | $6.40M | $24.74M | 0.12% | +$18.34M |
| Generate Biomedicines, Inc.(GENB) | 1,423,602 | 1,423,602 | 0 | $17.80M | $24.02M | 0.12% | +$6.22M |
| DBV Technologies S.A.ADS(DBVT) | 1,461,425 | 1,461,425 | 0 | $30.53M | $23.97M | 0.12% | -$6.56M |
| Xenon Pharmaceuticals Inc.(XENE) | 370,208 | 370,208 | 0 | $21.53M | $22.35M | 0.11% | +$818.2K |
| Tectonic Therapeutic, Inc.(TECX) | 607,788 | 607,788 | 0 | $18.79M | $20.89M | 0.10% | +$2.11M |
| Cerus Corporation(CERS) | 10,008,345 | 6,395,431 | -3,612,914 | $18.22M | $18.67M | 0.09% | +$459.5K |
| CytomX Therapeutics, Inc.(CTMX) | 4,975,826 | 4,975,826 | 0 | $23.39M | $18.66M | 0.09% | -$4.73M |
| Dyne Therapeutics, Inc.(DYN) | 813,449 | 813,449 | 0 | $14.75M | $18.07M | 0.09% | +$3.32M |
| Cytokinetics, Incorporated(CYTK) | 0 | 211,267 | +211,267 | $0 | $18.00M | 0.09% | +$18.00M |
| Xencor, Inc.(XNCR) | 1,102,106 | 1,102,106 | 0 | $13.29M | $17.74M | 0.09% | +$4.45M |
| Sionna Therapeutics, Inc.(SION) | 400,000 | 400,000 | 0 | $16.04M | $17.60M | 0.09% | +$1.56M |
| Intellia Therapeutics, Inc.(NTLA) | 0 | 930,232 | +930,232 | $0 | $15.74M | 0.08% | +$15.74M |
| Parabilis Medicines, Inc. | 0 | 500,000 | +500,000 | $0 | $13.69M | 0.07% | +$13.69M |
| MapLight Therapeutics, Inc.(MPLT) | 364,705 | 364,705 | 0 | $7.41M | $13.07M | 0.07% | +$5.66M |
| Avalyn Pharma Inc. | 0 | 350,000 | +350,000 | $0 | $11.52M | 0.06% | +$11.52M |
| Evommune, Inc.(EVMN) | 847,390 | 847,390 | 0 | $19.48M | $11.26M | 0.06% | -$8.22M |
| BioNTech SEADS(BNTX) | 119,743 | 119,743 | 0 | $10.64M | $11.14M | 0.06% | +$499.3K |
| Tango Therapeutics, Inc.(TNGX) | 0 | 333,333 | +333,333 | $0 | $10.42M | 0.05% | +$10.42M |
| Avalo Therapeutics, Inc.(AVTX) | 0 | 550,000 | +550,000 | $0 | $10.16M | 0.05% | +$10.16M |
| Sera Prognostics, Inc.CL A(SERA) | 5,498,170 | 5,498,170 | 0 | $11.16M | $10.01M | 0.05% | -$1.15M |
| Verastem, Inc.(VSTM) | 584,757 | 2,499,338 | +1,914,581 | $3.10M | $9.55M | 0.05% | +$6.45M |
| Sagimet Biosciences Inc.COM SER A(SGMT) | 952,996 | 952,996 | 0 | $4.98M | $7.37M | 0.04% | +$2.39M |
| Eikon Therapeutics, Inc.(EIKN) | 555,555 | 555,555 | 0 | $5.88M | $7.25M | 0.04% | +$1.37M |
| LB Pharmaceuticals Inc(LBRX) | 200,000 | 200,000 | 0 | $4.93M | $6.49M | 0.03% | +$1.56M |
| vTv Therapeutics Inc.CL A(VTVT) | 148,314 | 148,314 | 0 | $5.88M | $5.58M | 0.03% | -$298.1K |
| Wave Life Sciences, Inc.SHS(WVE) | 822,638 | 822,638 | 0 | $5.96M | $4.78M | 0.02% | -$1.18M |
| Protara Therapeutics, Inc.(TARA) | 971,614 | 971,614 | 0 | $5.06M | $3.71M | 0.02% | -$1.35M |
| TScan Therapeutics, Inc.(TCRX) | 2,784,792 | 2,784,792 | 0 | $2.81M | $2.73M | 0.01% | -$83.3K |
| Immunome, Inc.(IMNM) | 0 | 55,306 | +55,306 | $0 | $1.17M | 0.01% | +$1.17M |
| Skye Bioscience, Inc.(SKYE) | 1,575,243 | 1,575,243 | 0 | $968.1K | $1.09M | 0.01% | +$124.0K |
| Sana Biotechnology, Inc.(SANA) | 310,483 | 310,483 | 0 | $894.2K | $1.08M | 0.01% | +$189.4K |
| Aligos Therapeutics, Inc.(ALGS) | 83,055 | 83,055 | 0 | $617.1K | $479.2K | 0.00% | -$137.9K |
| Tyra Biosciences, Inc.(TYRA) | 10,607 | 10,607 | 0 | $406.2K | $338.8K | 0.00% | -$67.5K |
| Surrozen, Inc.W EXP 8 11 2026(SRZN) | 833,333 | 833,333 | 0 | $13.3K | $13.8K | 0.00% | +$417 |
| ABIVAX Société AnonymeADS(ABVX) | 875,796 | 0 | -875,796 | $97.52M | $0 | — | -$97.52M |
| argenx SEADR(ARGX) | 25,174 | 0 | -25,174 | $18.38M | $0 | — | -$18.38M |
| Centessa Pharmaceuticals plcADS | 670,751 | 0 | -670,751 | $26.64M | $0 | — | -$26.64M |
| COMPASS Pathways plcADS(CMPS) | 2,344,720 | 0 | -2,344,720 | $12.97M | $0 | — | -$12.97M |
| Contineum Therapeutics, Inc.CL A(CTNM) | 1,420,838 | 0 | -1,420,838 | $18.56M | $0 | — | -$18.56M |
| Immunocore Holdings plcADS(IMCR) | 734,397 | 0 | -734,397 | $22.14M | $0 | — | -$22.14M |
| Pharvaris N.V. COM | 375,000 | 0 | -375,000 | $10.59M | $0 | — | -$10.59M |
| Spyre Therapeutics, Inc.(SYRE) | 1,000,000 | 0 | -1,000,000 | $50.44M | $0 | — | -$50.44M |