Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q3 2025 ▲▼ | Q4 2025 ▲▼ | Change ▲▼ | Q3 2025 ▲▼ | Q4 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Evommune, Inc.(EVMN) | 0 | 589,005 | +589,005 | $0 | $10.08M | 8.08% | +$10.08M |
| Contineum Therapeutics, Inc.CL A(CTNM) | 800,787 | 800,787 | 0 | $9.41M | $9.15M | 7.34% | -$256.3K |
| Eli Lilly and Company(LLY) | 9,376 | 7,276 | -2,100 | $7.15M | $7.82M | 6.27% | +$665.5K |
| Shoulder Innovations, Inc.(SI) | 430,282 | 492,435 | +62,153 | $5.40M | $7.04M | 5.64% | +$1.64M |
| UnitedHealth Group Incorporated(UNH) | 13,545 | 13,595 | +50 | $4.68M | $4.49M | 3.60% | -$189.2K |
| Amgen Inc.(AMGN) | 10,340 | 13,070 | +2,730 | $2.92M | $4.28M | 3.43% | +$1.36M |
| Johnson & Johnson(JNJ) | 15,300 | 20,300 | +5,000 | $2.84M | $4.20M | 3.37% | +$1.36M |
| AbbVie Inc.(ABBV) | 14,800 | 16,800 | +2,000 | $3.43M | $3.84M | 3.08% | +$411.8K |
| Vertex Pharmaceuticals Incorporated(VRTX) | 7,715 | 8,005 | +290 | $3.02M | $3.63M | 2.91% | +$607.6K |
| Abbott Labs | 17,198 | 23,498 | +6,300 | $2.30M | $2.94M | 2.36% | +$640.6K |
| Regeneron Pharmaceuticals, Inc.(REGN) | 3,968 | 3,715 | -253 | $2.23M | $2.87M | 2.30% | +$636.4K |
| Intuitive Surgical, Inc.(ISRG) | 5,750 | 4,850 | -900 | $2.57M | $2.75M | 2.20% | +$175.3K |
| Boston Scientific Corporation(BSX) | 22,126 | 27,626 | +5,500 | $2.16M | $2.63M | 2.11% | +$474.0K |
| argenx SEADR(ARGX) | 3,890 | 2,894 | -996 | $2.87M | $2.43M | 1.95% | -$435.4K |
| Danaher Corporation(DHR) | 10,575 | 10,575 | 0 | $2.10M | $2.42M | 1.94% | +$321.9K |
| Stryker Corporation(SYK) | 4,300 | 6,550 | +2,250 | $1.59M | $2.30M | 1.85% | +$710.0K |
| Thermo Fisher Scientific Inc.(TMO) | 3,900 | 3,900 | 0 | $1.89M | $2.26M | 1.81% | +$367.1K |
| Merck & Co., Inc.(MRK) | 16,400 | 21,400 | +5,000 | $1.39M | $2.25M | 1.81% | +$866.8K |
| Gilead Sciences, Inc.(GILD) | 19,550 | 17,885 | -1,665 | $2.17M | $2.20M | 1.76% | +$25.2K |
| Insmed Incorporated(INSM) | 13,425 | 11,182 | -2,243 | $1.93M | $1.95M | 1.56% | +$12.8K |
| DexCom, Inc.(DXCM) | 20,700 | 28,700 | +8,000 | $1.39M | $1.90M | 1.53% | +$511.9K |
| Vera Therapeutics, Inc.CL A(VERA) | 30,188 | 36,858 | +6,670 | $877.3K | $1.87M | 1.50% | +$989.2K |
| Structure TherapeuticsADR | 221,872 | 23,872 | -198,000 | $6.21M | $1.66M | 1.33% | -$4.55M |
| BioNTech SEADR(BNTX) | 17,660 | 17,218 | -442 | $1.74M | $1.64M | 1.31% | -$102.5K |
| Edwards Lifescience | 15,000 | 17,250 | +2,250 | $1.17M | $1.47M | 1.18% | +$304.0K |
| AstraZeneca PLCADR(AZN) | 18,750 | 15,232 | -3,518 | $1.44M | $1.40M | 1.12% | -$38.2K |
| Summit Therapeutics Inc.(SMMT) | 74,070 | 79,625 | +5,555 | $1.53M | $1.39M | 1.12% | -$137.6K |
| Arcus Biosciences, Inc.(RCUS) | 368,070 | 56,945 | -311,125 | $5.01M | $1.36M | 1.09% | -$3.65M |
| Syndax Pharmaceuticals, Inc.(SNDX) | 79,430 | 61,200 | -18,230 | $1.22M | $1.29M | 1.03% | +$63.8K |
| Tarsus Pharmaceuticals, Inc.(TARS) | 18,405 | 14,740 | -3,665 | $1.09M | $1.21M | 0.97% | +$113.1K |
| Alnylam Pharmaceuticals, Inc.(ALNY) | 3,273 | 2,990 | -283 | $1.49M | $1.19M | 0.95% | -$303.5K |
| Rapport Therapeutics, Inc.(RAPP) | 43,480 | 38,925 | -4,555 | $1.29M | $1.18M | 0.95% | -$110.4K |
| Cogent Biosciences, Inc.(COGT) | 0 | 32,685 | +32,685 | $0 | $1.16M | 0.93% | +$1.16M |
| Mineralys Therapeutics, Inc.(MLYS) | 33,885 | 31,625 | -2,260 | $1.28M | $1.15M | 0.92% | -$137.2K |
| Trevi Therapeutics, Inc.(TRVI) | 105,950 | 84,255 | -21,695 | $969.4K | $1.05M | 0.85% | +$85.4K |
| Roivant Sciences Ltd.SHS(ROIV) | 50,007 | 45,347 | -4,660 | $756.6K | $984.0K | 0.79% | +$227.4K |
| Tectonic Therapeutic, Inc.(TECX) | 192,770 | 42,255 | -150,515 | $3.02M | $881.4K | 0.71% | -$2.14M |
| Ventyx Biosciences | 1,107,267 | 96,945 | -1,010,322 | $3.44M | $875.4K | 0.70% | -$2.57M |
| BridgeBio Pharma, Inc.(BBIO) | 13,650 | 11,170 | -2,480 | $709.0K | $854.4K | 0.68% | +$145.4K |
| United Therapeutics Corporation(UTHR) | 765 | 1,723 | +958 | $320.7K | $839.5K | 0.67% | +$518.8K |
| Boundless Bio, Inc.(BOLD) | 678,574 | 678,574 | 0 | $834.6K | $814.3K | 0.65% | -$20.4K |
| BeOne Medicines AGADR(ONC) | 7,201 | 2,665 | -4,536 | $2.45M | $809.7K | 0.65% | -$1.64M |
| RadNet, Inc.(RDNT) | 10,000 | 11,000 | +1,000 | $762.1K | $784.9K | 0.63% | +$22.8K |
| ArriVent BioPharma, Inc.(AVBP) | 39,235 | 38,255 | -980 | $723.9K | $769.7K | 0.62% | +$45.8K |
| uniQure N.V.SHS(QURE) | 30,740 | 30,585 | -155 | $1.79M | $731.9K | 0.59% | -$1.06M |
| Ascendis Pharma A/SADR(ASND) | 3,601 | 3,254 | -347 | $715.9K | $693.9K | 0.56% | -$22.0K |
| LENZ Therapeutics, Inc.(LENZ) | 0 | 42,500 | +42,500 | $0 | $680.0K | 0.55% | +$680.0K |
| Pfizer Inc.(PFE) | 77,150 | 27,150 | -50,000 | $1.97M | $676.0K | 0.54% | -$1.29M |
| Inspire Medical Systems, Inc.(INSP) | 0 | 7,200 | +7,200 | $0 | $664.1K | 0.53% | +$664.1K |
| Ionis Pharmaceuticals, Inc.(IONS) | 9,205 | 8,365 | -840 | $602.2K | $661.8K | 0.53% | +$59.6K |
| Immatics N.V.SHS(IMTX) | 560,494 | 63,015 | -497,479 | $4.78M | $661.7K | 0.53% | -$4.11M |
| Hinge Health, Inc.CL A(HNGE) | 11,206 | 14,206 | +3,000 | $550.0K | $659.9K | 0.53% | +$109.9K |
| BioMarin Pharmaceutical Inc.(BMRN) | 25,030 | 10,880 | -14,150 | $1.36M | $646.6K | 0.52% | -$709.0K |
| Alignment Healthcare, Inc.(ALHC) | 54,500 | 31,500 | -23,000 | $951.0K | $622.1K | 0.50% | -$328.9K |
| Amicus Therapeutics COM | 119,105 | 43,300 | -75,805 | $938.5K | $616.6K | 0.49% | -$322.0K |
| Privia Health Group, Inc.(PRVA) | 36,500 | 26,000 | -10,500 | $908.9K | $616.5K | 0.49% | -$292.4K |
| Carlsmed, Inc.(CARL) | 0 | 47,700 | +47,700 | $0 | $589.1K | 0.47% | +$589.1K |
| PTC Therapeutics, Inc.(PTCT) | 8,535 | 7,715 | -820 | $523.8K | $586.0K | 0.47% | +$62.2K |
| Omada Health, Inc.(OMDA) | 27,500 | 36,500 | +9,000 | $608.0K | $576.0K | 0.46% | -$32.1K |
| Nektar Therapeutics(NKTR) | 0 | 13,485 | +13,485 | $0 | $570.1K | 0.46% | +$570.1K |
| Kura Oncology, Inc.(KURA) | 395,872 | 54,110 | -341,762 | $3.50M | $562.2K | 0.45% | -$2.94M |
| Neurocrine Biosciences, Inc.(NBIX) | 2,960 | 2,675 | -285 | $415.5K | $379.4K | 0.30% | -$36.1K |
| Biogen Inc.(BIIB) | 2,375 | 2,155 | -220 | $332.7K | $379.3K | 0.30% | +$46.6K |
| Cytokinetics, Incorporated(CYTK) | 10,223 | 5,893 | -4,330 | $561.9K | $374.4K | 0.30% | -$187.4K |
| Jazz Pharmaceuticals plcSHS USD(JAZZ) | 2,244 | 2,049 | -195 | $295.8K | $348.3K | 0.28% | +$52.6K |
| ARS Pharmaceuticals, Inc.(SPRY) | 81,785 | 29,803 | -51,982 | $821.9K | $347.2K | 0.28% | -$474.7K |
| Royalty Pharma plcCL A(RPRX) | 9,280 | 8,470 | -810 | $327.4K | $327.3K | 0.26% | -$117 |
| Illumina, Inc.(ILMN) | 2,727 | 2,472 | -255 | $259.0K | $324.2K | 0.26% | +$65.2K |
| Axsome Therapeutics, Inc.(AXSM) | 1,020 | 1,740 | +720 | $123.9K | $317.8K | 0.25% | +$193.9K |
| Incyte Corporation(INCY) | 3,030 | 2,750 | -280 | $257.0K | $271.6K | 0.22% | +$14.6K |
| Tempus AI, Inc.CL A(TEM) | 3,760 | 4,500 | +740 | $303.5K | $265.7K | 0.21% | -$37.7K |
| Madrigal Pharmaceuticals, Inc.(MDGL) | 730 | 352 | -378 | $334.8K | $205.0K | 0.16% | -$129.8K |
| ORIC Pharmaceuticals, Inc.(ORIC) | 328,655 | 22,480 | -306,175 | $3.94M | $183.9K | 0.15% | -$3.76M |
| Moderna, Inc.(MRNA) | 5,600 | 5,005 | -595 | $144.6K | $147.6K | 0.12% | +$3.0K |
| Anaptysbio Inc | 194,485 | 0 | -194,485 | $5.96M | $0 | — | -$5.96M |
| Bicara Therapeutics | 266,495 | 0 | -266,495 | $4.21M | $0 | — | -$4.21M |
| Bristol-Myers Squibb Company(BMY) | 10,800 | 0 | -10,800 | $487.1K | $0 | — | -$487.1K |
| The Cigna Group(CI) | 1,800 | 0 | -1,800 | $518.9K | $0 | — | -$518.9K |
| Instil Bio, Inc.(TIL) | 161,380 | 0 | -161,380 | $2.88M | $0 | — | -$2.88M |
| MBX Biosciences, Inc.(MBX) | 194,898 | 0 | -194,898 | $3.41M | $0 | — | -$3.41M |
| MoonLake ImmunotherapeuticsCL A(MLTX) | 956 | 0 | -956 | $6.9K | $0 | — | -$6.9K |
| Palvella Therapeutics, Inc.(PVLA) | 49,115 | 0 | -49,115 | $3.08M | $0 | — | -$3.08M |
| Spdr Series TrustS P BIOTECH ST STR SP BIOT | 34,000 | 0 | -34,000 | $3.41M | $0 | — | -$3.41M |
| Solid Biosciences | 633,052 | 0 | -633,052 | $3.91M | $0 | — | -$3.91M |
| Vaxcyte, Inc.(PCVX) | 4,205 | 0 | -4,205 | $151.5K | $0 | — | -$151.5K |
| Zai Lab LimitedADR(ZLAB) | 12,590 | 0 | -12,590 | $426.7K | $0 | — | -$426.7K |
| Zenas BioPharma, Inc.(ZBIO) | 152,025 | 0 | -152,025 | $3.37M | $0 | — | -$3.37M |
| Merus B V | 11,545 | 0 | -11,545 | $1.09M | $0 | — | -$1.09M |