Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q4 2024 ▲▼ | Q1 2025 ▲▼ | Change ▲▼ | Q4 2024 ▲▼ | Q1 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| AKEBIA THERAPEUTICS INC(AKBA) | 0 | 4,973,840 | +4,973,840 | 0 | 9,550 | 5.19% | +9,550 |
| ASCENDIS PHARMA A/S(ASND) | 0 | 50,000 | +50,000 | 0 | 7,793 | 4.24% | +7,793 |
| AMYLYX PHARMACEUTICALS INC(AMLX) | 0 | 1,811,996 | +1,811,996 | 0 | 6,414 | 3.49% | +6,414 |
| IMMUNOVANT INC(IMVT) | 0 | 375,000 | +375,000 | 0 | 6,409 | 3.48% | +6,409 |
| LEGEND BIOTECH CORP(LEGN) | 0 | 138,240 | +138,240 | 0 | 4,690 | 2.55% | +4,690 |
| VAXCYTE INC(PCVX) | 0 | 115,517 | +115,517 | 0 | 4,362 | 2.37% | +4,362 |
| BEAM THERAPEUTICS INC(BEAM) | 0 | 175,562 | +175,562 | 0 | 3,429 | 1.86% | +3,429 |
| MERUS N V | 158,092 | 237,156 | +79,064 | 6,648 | 9,982 | 5.43% | +3,334 |
| ARCELLX INC COMMON STOCK | 0 | 45,000 | +45,000 | 0 | 2,952 | 1.60% | +2,952 |
| CENTESSA PHARMACEUTICALS PLC | 0 | 149,702 | +149,702 | 0 | 2,153 | 1.17% | +2,153 |
| EVOLUS INC(EOLS) | 895,524 | 944,743 | +49,219 | 9,887 | 11,365 | 6.18% | +1,479 |
| REZOLUTE INC(RZLT) | 621,894 | 833,042 | +211,148 | 3,047 | 2,416 | 1.31% | -631 |
| PROMIS NEUROSCIENCES INC | 2,645,128 | 2,645,128 | 0 | 2,507 | 1,840 | 1.00% | -667 |
| DIANTHUS THERAPEUTICS INC(DNTH) | 275,000 | 275,000 | 0 | 5,995 | 4,989 | 2.71% | -1,006 |
| HELIX ACQUISITION CORP II | 500,000 | 373,833 | -126,167 | 5,250 | 4,224 | 2.30% | -1,026 |
| MEREO BIOPHARMA GROUP PLC(MREO) | 1,150,000 | 1,275,000 | +125,000 | 4,025 | 2,869 | 1.56% | -1,156 |
| XENON PHARMACEUTICALS INC(XENE) | 245,272 | 245,272 | 0 | 9,615 | 8,229 | 4.47% | -1,386 |
| ABIVAX SA(ABVX) | 1,648,523 | 1,638,111 | -10,412 | 12,067 | 10,238 | 5.57% | -1,829 |
| UROGEN PHARMA LTD(URGN) | 187,843 | 0 | -187,843 | 2,001 | 0 | — | -2,001 |
| CONTEXT THERAPEUTICS INC(CNTX) | 4,683,711 | 4,683,711 | 0 | 4,918 | 2,866 | 1.56% | -2,051 |
| CYTOKINETICS INC(CYTK) | 360,000 | 370,000 | +10,000 | 16,934 | 14,870 | 8.08% | -2,064 |
| UNICYCIVE THERAPEUTICS INC | 10,980,000 | 10,980,000 | 0 | 8,720 | 6,312 | 3.43% | -2,408 |
| OPTINOSE INC | 370,269 | 0 | -370,269 | 2,473 | 0 | — | -2,473 |
| VOYAGER THERAPEUTICS INC(VYGR) | 826,751 | 626,275 | -200,476 | 4,688 | 2,117 | 1.15% | -2,571 |
| AUTOLUS THERAPEUTICS PLC(AUTL) | 3,009,392 | 2,728,910 | -280,482 | 7,072 | 4,230 | 2.30% | -2,842 |
| UPSTREAM BIO INC(UPB) | 300,000 | 300,000 | 0 | 4,932 | 1,836 | 1.00% | -3,096 |
| DYNAVAX TECHNOLOGIES CORP | 860,000 | 595,879 | -264,121 | 10,982 | 7,729 | 4.20% | -3,254 |
| KALVISTA PHARMACEUTICALS INC | 1,787,003 | 1,014,367 | -772,636 | 15,136 | 11,706 | 6.36% | -3,430 |
| ZURA BIO LTD(ZURA) | 3,170,194 | 3,170,194 | 0 | 7,925 | 4,090 | 2.22% | -3,836 |
| VIRIDIAN THERAPEUTICS INC(VRDN) | 750,000 | 750,000 | 0 | 14,378 | 10,110 | 5.50% | -4,267 |
| ORUKA THERAPEUTICS INC(ORKA) | 228,803 | 0 | -228,803 | 4,436 | 0 | — | -4,436 |
| NEUROGENE INC(NGNE) | 442,761 | 470,964 | +28,203 | 10,122 | 5,515 | 3.00% | -4,607 |
| JASPER THERAPEUTICS INC(JSPR) | 322,380 | 0 | -322,380 | 6,892 | 0 | — | -6,892 |
| IONIS PHARMACEUTICALS INC(IONS) | 505,007 | 250,000 | -255,007 | 17,655 | 7,543 | 4.10% | -10,113 |
| PLIANT THERAPEUTICS INC(PLRX) | 1,055,000 | 850,000 | -205,000 | 13,894 | 1,148 | 0.62% | -12,747 |