Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q3 2024 ▲▼ | Q4 2024 ▲▼ | Change ▲▼ | Q3 2024 ▲▼ | Q4 2024 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| XENON PHARMACEUTICALS INC(XENE) | 0 | 245,272 | +245,272 | 0 | 9,615 | 4.53% | +9,615 |
| IONIS PHARMACEUTICALS INC(IONS) | 255,000 | 505,007 | +250,007 | 10,215 | 17,655 | 8.32% | +7,440 |
| UNICYCIVE THERAPEUTICS INC | 8,559,000 | 10,980,000 | +2,421,000 | 3,491 | 8,720 | 4.11% | +5,229 |
| UPSTREAM BIO INC(UPB) | 0 | 300,000 | +300,000 | 0 | 4,932 | 2.32% | +4,932 |
| MEREO BIOPHARMA GROUP PLC(MREO) | 0 | 1,150,000 | +1,150,000 | 0 | 4,025 | 1.90% | +4,025 |
| REZOLUTE INC(RZLT) | 0 | 621,894 | +621,894 | 0 | 3,047 | 1.44% | +3,047 |
| OPTINOSE INC | 0 | 370,269 | +370,269 | 0 | 2,473 | 1.17% | +2,473 |
| JASPER THERAPEUTICS INC(JSPR) | 322,380 | 322,380 | 0 | 6,064 | 6,892 | 3.25% | +829 |
| CYTOKINETICS INC(CYTK) | 316,000 | 360,000 | +44,000 | 16,685 | 16,934 | 7.98% | +250 |
| KALVISTA PHARMACEUTICALS INC | 1,299,503 | 1,787,003 | +487,500 | 15,048 | 15,136 | 7.13% | +88 |
| HELIX ACQUISITION CORP II | 500,000 | 500,000 | 0 | 5,225 | 5,250 | 2.47% | +25 |
| VOYAGER THERAPEUTICS INC(VYGR) | 959,953 | 826,751 | -133,202 | 5,616 | 4,688 | 2.21% | -928 |
| PROMIS NEUROSCIENCES INC | 2,790,698 | 2,645,128 | -145,570 | 3,488 | 2,507 | 1.18% | -981 |
| ELIEM THERAPEUTICS INC(CLYM) | 248,168 | 0 | -248,168 | 1,263 | 0 | — | -1,263 |
| DIANTHUS THERAPEUTICS INC(DNTH) | 275,000 | 275,000 | 0 | 7,530 | 5,995 | 2.83% | -1,534 |
| VISTAGEN THERAPEUTICS INC(VTGN) | 674,075 | 0 | -674,075 | 2,029 | 0 | — | -2,029 |
| VIRIDIAN THERAPEUTICS INC(VRDN) | 750,000 | 750,000 | 0 | 17,063 | 14,378 | 6.78% | -2,685 |
| AUTOLUS THERAPEUTICS PLC(AUTL) | 2,811,955 | 3,009,392 | +197,437 | 10,207 | 7,072 | 3.33% | -3,135 |
| CARTESIAN THERAPEUTICS INC(RNAC) | 200,000 | 0 | -200,000 | 3,224 | 0 | — | -3,224 |
| DYNAVAX TECHNOLOGIES CORP | 1,326,234 | 860,000 | -466,234 | 14,774 | 10,982 | 5.18% | -3,792 |
| TSCAN THERAPEUTICS INC(TCRX) | 1,016,375 | 0 | -1,016,375 | 5,062 | 0 | — | -5,062 |
| ZURA BIO LTD(ZURA) | 3,263,672 | 3,170,194 | -93,478 | 13,251 | 7,925 | 3.73% | -5,325 |
| MERUS N V | 250,000 | 158,092 | -91,908 | 12,490 | 6,648 | 3.13% | -5,842 |
| OUTLOOK THERAPEUTICS INC(OTLK) | 1,293,028 | 0 | -1,293,028 | 6,905 | 0 | — | -6,905 |
| PLIANT THERAPEUTICS INC(PLRX) | 1,910,121 | 1,055,000 | -855,121 | 21,412 | 13,894 | 6.55% | -7,518 |
| UROGEN PHARMA LTD(URGN) | 758,786 | 187,843 | -570,943 | 9,637 | 2,001 | 0.94% | -7,636 |
| ORUKA THERAPEUTICS INC(ORKA) | 514,659 | 228,803 | -285,856 | 12,614 | 4,436 | 2.09% | -8,178 |
| ARCELLX INC COMMON STOCK | 100,000 | 0 | -100,000 | 8,351 | 0 | — | -8,351 |
| OPTINOSE INC | 12,861,136 | 0 | -12,861,136 | 8,617 | 0 | — | -8,617 |
| CONTEXT THERAPEUTICS INC(CNTX) | 6,934,982 | 4,683,711 | -2,251,271 | 13,593 | 4,918 | 2.32% | -8,675 |
| EVOLUS INC(EOLS) | 1,170,000 | 895,524 | -274,476 | 18,954 | 9,887 | 4.66% | -9,067 |
| OLEMA PHARMACEUTICALS INC(OLMA) | 1,000,000 | 0 | -1,000,000 | 11,940 | 0 | — | -11,940 |
| ABIVAX SA(ABVX) | 2,128,773 | 1,648,523 | -480,250 | 24,523 | 12,067 | 5.69% | -12,456 |
| NEUROGENE INC(NGNE) | 1,004,291 | 442,761 | -561,530 | 42,140 | 10,122 | 4.77% | -32,019 |