Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q4 2023 ▲▼ | Q1 2024 ▲▼ | Change ▲▼ | Q4 2023 ▲▼ | Q1 2024 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Insmed Incorporated(INSM) | 5,511,721 | 4,423,369 | -1,088,352 | $170.81M | $120.01M | 13.53% | -$50.80M |
| Amicus Therapeutics Inc COM | 10,373,715 | 9,344,102 | -1,029,613 | $147.20M | $110.07M | 12.41% | -$37.13M |
| BioMarin Pharmaceutical Inc.(BMRN) | 1,500,749 | 1,134,569 | -366,180 | $144.70M | $99.09M | 11.18% | -$45.61M |
| Biogen Inc.(BIIB) | 380,417 | 289,958 | -90,459 | $98.44M | $62.52M | 7.05% | -$35.92M |
| United Therapeutics Corporation(UTHR) | 395,784 | 267,759 | -128,025 | $87.03M | $61.51M | 6.94% | -$25.52M |
| STAAR Surgical Company(STAA) | 1,376,950 | 1,379,590 | +2,640 | $42.97M | $52.81M | 5.96% | +$9.84M |
| Acadia Pharmaceuticals Inc | 2,409,556 | 2,414,943 | +5,387 | $75.44M | $44.65M | 5.04% | -$30.79M |
| Prothena Corp PlcSHS SHS | 1,660,057 | 1,663,448 | +3,391 | $60.33M | $41.20M | 4.65% | -$19.12M |
| Iovance Biotherapeutics, Inc.(IOVA) | 2,106,792 | 2,112,811 | +6,019 | $17.13M | $31.31M | 3.53% | +$14.18M |
| Alnylam Pharmaceuticals, Inc.(ALNY) | 154,437 | 182,766 | +28,329 | $29.56M | $27.31M | 3.08% | -$2.25M |
| Sarepta Therapeutics, Inc.(SRPT) | 200,905 | 201,265 | +360 | $19.37M | $26.06M | 2.94% | +$6.68M |
| Revance Therapeutics Inc | 5,237,284 | 5,248,004 | +10,720 | $46.04M | $25.82M | 2.91% | -$20.22M |
| Sage Therapeutics Inc | 991,525 | 1,005,776 | +14,251 | $21.49M | $18.85M | 2.13% | -$2.64M |
| Anaptysbio Inc | 686,882 | 799,906 | +113,024 | $14.71M | $18.01M | 2.03% | +$3.30M |
| eHealth, Inc.(EHTH) | 2,739,379 | 2,715,681 | -23,698 | $23.89M | $16.38M | 1.85% | -$7.51M |
| Align Technology Inc | 55,705 | 49,105 | -6,600 | $15.26M | $16.10M | 1.82% | +$839.3K |
| Alkermes plcSHS(ALKS) | 603,400 | 495,592 | -107,808 | $16.74M | $13.42M | 1.51% | -$3.32M |
| Acelyrin Inc | 0 | 1,715,180 | +1,715,180 | $0 | $11.58M | 1.31% | +$11.58M |
| Nevro Corp | 750,371 | 750,371 | 0 | $16.15M | $10.84M | 1.22% | -$5.31M |
| Syndax Pharmaceuticals, Inc.(SNDX) | 472,600 | 405,193 | -67,407 | $10.21M | $9.64M | 1.09% | -$569.3K |
| NovoCure Limited(NVCR) | 561,908 | 561,908 | 0 | $8.39M | $8.78M | 0.99% | +$393.3K |
| Cytokinetics, Incorporated(CYTK) | 111,717 | 111,717 | 0 | $9.33M | $7.83M | 0.88% | -$1.49M |
| Karyopharm Therapeutics Inc.(KPTI) | 5,102,193 | 5,102,193 | 0 | $4.41M | $7.70M | 0.87% | +$3.29M |
| Verve Therapeutics Inc | 575,817 | 575,817 | 0 | $8.03M | $7.65M | 0.86% | -$380.0K |
| Gossamer Bio, Inc.(GOSS) | 5,958,888 | 6,391,775 | +432,887 | $6.53M | $7.54M | 0.85% | +$1.01M |
| Elevation Oncology Inc | 0 | 1,346,666 | +1,346,666 | $0 | $6.91M | 0.78% | +$6.91M |
| Bluebird Bio Inc | 3,333,333 | 4,560,171 | +1,226,838 | $4.60M | $5.84M | 0.66% | +$1.24M |
| Relmada Therapeutics, Inc.(RLMD) | 732,400 | 732,400 | 0 | $3.03M | $3.41M | 0.38% | +$373.5K |
| Nuvation Bio Inc.(NUVB) | 0 | 772,652 | +772,652 | $0 | $2.81M | 0.32% | +$2.81M |
| Taysha Gene Therapies, Inc.(TSHA) | 529,861 | 811,268 | +281,407 | $937.9K | $2.33M | 0.26% | +$1.39M |
| Stoke Therapeutics, Inc.(STOK) | 0 | 125,861 | +125,861 | $0 | $1.70M | 0.19% | +$1.70M |
| Mirum Pharmaceuticals, Inc.(MIRM) | 64,700 | 64,700 | 0 | $1.91M | $1.63M | 0.18% | -$284.7K |
| Humana Inc.(HUM) | 0 | 3,985 | +3,985 | $0 | $1.38M | 0.16% | +$1.38M |
| Yarrow Bioscience Inc(YARW) | 445,434 | 445,434 | 0 | $1.04M | $1.37M | 0.15% | +$329.6K |
| Travere Therapeutics, Inc.(TVTX) | 110,719 | 110,719 | 0 | $995.4K | $853.6K | 0.10% | -$141.7K |
| Aldeyra Therapeutics, Inc.(ALDX) | 225,465 | 225,465 | 0 | $791.4K | $737.3K | 0.08% | -$54.1K |
| Aclaris Therapeutics, Inc.(ACRS) | 0 | 569,832 | +569,832 | $0 | $706.6K | 0.08% | +$706.6K |
| UroGen Pharma Ltd.(URGN) | 24,500 | 24,500 | 0 | $367.5K | $367.5K | 0.04% | $0 |
| Sight Sciences, Inc.(SGHT) | 173,790 | 0 | -173,790 | $896.8K | $0 | — | -$896.8K |
| Vanda Pharmaceuticals Inc.(VNDA) | 278,985 | 0 | -278,985 | $1.18M | $0 | — | -$1.18M |