Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q2 2025 ▲▼ | Q3 2025 ▲▼ | Change ▲▼ | Q2 2025 ▲▼ | Q3 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Insmed Incorporated(INSM) | 865,113 | 491,805 | -373,308 | $87.06M | $70.82M | 13.11% | -$16.24M |
| PTC Therapeutics, Inc.(PTCT) | 406,469 | 862,613 | +456,144 | $19.85M | $52.94M | 9.80% | +$33.09M |
| Acadia Pharmaceuticals Inc | 2,563,209 | 2,466,684 | -96,525 | $55.29M | $52.64M | 9.74% | -$2.65M |
| Amicus Therapeutics Inc COM | 5,610,513 | 5,367,798 | -242,715 | $32.15M | $42.30M | 7.83% | +$10.15M |
| BioMarin Pharmaceutical Inc.(BMRN) | 840,470 | 754,007 | -86,463 | $46.20M | $40.84M | 7.56% | -$5.36M |
| Biogen Inc.ADS(BIIB) | 205,759 | 185,661 | -20,098 | $25.84M | $26.01M | 4.81% | +$166.1K |
| United Therapeutics Corporation(UTHR) | 95,482 | 58,186 | -37,296 | $27.44M | $24.39M | 4.51% | -$3.04M |
| Anaptysbio Inc | 812,821 | 673,520 | -139,301 | $18.04M | $20.62M | 3.82% | +$2.58M |
| Iovance Biotherapeutics, Inc.(IOVA) | 3,429,329 | 7,618,132 | +4,188,803 | $5.90M | $16.53M | 3.06% | +$10.63M |
| NovoCure Limited(NVCR) | 962,396 | 1,256,159 | +293,763 | $17.13M | $16.23M | 3.00% | -$901.1K |
| Dyne Therapeutics, Inc.ADS(DYN) | 264,976 | 1,262,674 | +997,698 | $2.52M | $15.97M | 2.96% | +$13.45M |
| Disc Medicine, Inc.(IRON) | 145,691 | 224,300 | +78,609 | $7.72M | $14.82M | 2.74% | +$7.11M |
| Alnylam Pharmaceuticals, Inc.(ALNY) | 75,535 | 32,320 | -43,215 | $24.63M | $14.74M | 2.73% | -$9.89M |
| Gossamer Bio, Inc.(GOSS) | 5,739,013 | 5,464,349 | -274,664 | $7.06M | $14.37M | 2.66% | +$7.31M |
| Prothena Corp PlcCL A SHS | 1,274,753 | 1,324,028 | +49,275 | $7.74M | $12.92M | 2.39% | +$5.18M |
| Ultragenyx Pharmaceutical Inc.(RARE) | 48,750 | 369,531 | +320,781 | $1.77M | $11.12M | 2.06% | +$9.34M |
| Agios Pharmaceuticals, Inc.(AGIO) | 268,783 | 265,497 | -3,286 | $8.94M | $10.66M | 1.97% | +$1.72M |
| Syndax Pharmaceuticals, Inc.(SNDX) | 444,367 | 654,930 | +210,563 | $4.16M | $10.08M | 1.86% | +$5.91M |
| eHealth, Inc.(EHTH) | 1,577,850 | 1,544,619 | -33,231 | $6.86M | $6.66M | 1.23% | -$206.3K |
| Denali Therapeutics Inc.(DNLI) | 239,809 | 408,006 | +168,197 | $3.35M | $5.92M | 1.10% | +$2.57M |
| Align Technology Inc | 37,772 | 45,735 | +7,963 | $7.15M | $5.73M | 1.06% | -$1.42M |
| Alkermes plc(ALKS) | 221,021 | 183,938 | -37,083 | $6.32M | $5.52M | 1.02% | -$805.3K |
| Avidity Biosciences Inc | 118,886 | 109,831 | -9,055 | $3.38M | $4.79M | 0.89% | +$1.41M |
| Mirum Pharmaceuticals, Inc.(MIRM) | 64,700 | 64,700 | 0 | $3.29M | $4.74M | 0.88% | +$1.45M |
| CareDx, Inc.(CDNA) | 0 | 316,204 | +316,204 | $0 | $4.60M | 0.85% | +$4.60M |
| Taysha Gene Therapies, Inc.(TSHA) | 1,246,033 | 1,246,033 | 0 | $2.88M | $4.07M | 0.75% | +$1.20M |
| Nuvation Bio Inc.CL A(NUVB) | 772,652 | 1,020,547 | +247,895 | $1.51M | $3.78M | 0.70% | +$2.27M |
| Aclaris Therapeutics, Inc.(ACRS) | 1,390,028 | 1,566,840 | +176,812 | $1.97M | $2.98M | 0.55% | +$1.00M |
| CRISPR Therapeutics AGNAMEN AKT(CRSP) | 44,625 | 41,226 | -3,399 | $2.17M | $2.67M | 0.49% | +$501.3K |
| Travere Therapeutics, Inc.(TVTX) | 110,719 | 110,719 | 0 | $1.64M | $2.65M | 0.49% | +$1.01M |
| Edwards Lifesciences Corp | 39,473 | 33,640 | -5,833 | $3.09M | $2.62M | 0.48% | -$471.0K |
| Neurocrine Biosciences, Inc.(NBIX) | 13,334 | 18,117 | +4,783 | $1.68M | $2.54M | 0.47% | +$867.3K |
| Stoke Therapeutics, Inc.(STOK) | 125,861 | 105,427 | -20,434 | $1.43M | $2.48M | 0.46% | +$1.05M |
| Pyxis Oncology, Inc.(PYXS) | 1,037,421 | 1,037,421 | 0 | $1.14M | $2.30M | 0.43% | +$1.16M |
| BioNTech SE(BNTX) | 25,206 | 19,614 | -5,592 | $2.68M | $1.93M | 0.36% | -$749.4K |
| Bicycle Therapeutics Plc-Adr | 248,934 | 221,071 | -27,863 | $1.73M | $1.71M | 0.32% | -$19.0K |
| Aldeyra Therapeutics, Inc.ADR(ALDX) | 225,465 | 225,465 | 0 | $863.5K | $1.18M | 0.22% | +$313.4K |
| Humana Inc.(HUM) | 3,985 | 3,985 | 0 | $974.3K | $1.04M | 0.19% | +$62.5K |
| Oruka Therapeutics, Inc.(ORKA) | 0 | 59,985 | +59,985 | $0 | $791.3K | 0.15% | +$791.3K |
| Abeona Therapeutics Inc.(ABEO) | 108,865 | 108,865 | 0 | $618.4K | $574.8K | 0.11% | -$43.5K |
| UroGen Pharma Ltd.(URGN) | 24,500 | 24,500 | 0 | $335.6K | $488.8K | 0.09% | +$153.1K |
| Proqr Therapeutics NvSHS EURO SHS EURO | 0 | 188,807 | +188,807 | $0 | $402.2K | 0.07% | +$402.2K |
| Akari Therapeutics, Plc(AKTX) | 146,024 | 146,024 | 0 | $170.8K | $147.5K | 0.03% | -$23.4K |
| Generation Bio Co | 150,475 | 15,047 | -135,428 | $48.2K | $92.1K | 0.02% | +$43.9K |
| Alumis Inc | 143,437 | 0 | -143,437 | $430.3K | $0 | — | -$430.3K |
| Karyopharm Therapeutics Inc.(KPTI) | 187,911 | 0 | -187,911 | $809.9K | $0 | — | -$809.9K |
| STAAR Surgical Company(STAA) | 791,879 | 0 | -791,879 | $13.29M | $0 | — | -$13.29M |
| Yarrow Bioscience Inc(YARW) | 445,434 | 0 | -445,434 | $735.0K | $0 | — | -$735.0K |