Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q3 2024 ▲▼ | Q4 2024 ▲▼ | Change ▲▼ | Q3 2024 ▲▼ | Q4 2024 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Insmed Incorporated(INSM) | 1,940,993 | 1,603,465 | -337,528 | $141.69M | $110.70M | 17.15% | -$30.99M |
| Amicus Therapeutics Inc COM | 8,145,311 | 7,662,479 | -482,832 | $86.99M | $72.18M | 11.18% | -$14.81M |
| BioMarin Pharmaceutical Inc.(BMRN) | 1,090,056 | 1,067,266 | -22,790 | $76.62M | $70.15M | 10.87% | -$6.47M |
| United Therapeutics Corporation(UTHR) | 183,246 | 155,714 | -27,532 | $65.67M | $54.94M | 8.51% | -$10.72M |
| Acadia Pharmaceuticals Inc | 2,523,956 | 2,748,599 | +224,643 | $38.82M | $50.44M | 7.82% | +$11.62M |
| Alnylam Pharmaceuticals, Inc.(ALNY) | 140,681 | 140,681 | 0 | $38.69M | $33.10M | 5.13% | -$5.59M |
| Biogen Inc.(BIIB) | 228,916 | 190,148 | -38,768 | $44.37M | $29.08M | 4.51% | -$15.30M |
| Sarepta Therapeutics, Inc.(SRPT) | 210,258 | 210,258 | 0 | $26.26M | $25.57M | 3.96% | -$693.9K |
| NovoCure Limited(NVCR) | 593,540 | 814,191 | +220,651 | $9.28M | $24.26M | 3.76% | +$14.99M |
| Prothena Corp PlcSHS SHS | 1,737,964 | 1,737,964 | 0 | $29.08M | $24.07M | 3.73% | -$5.01M |
| Iovance Biotherapeutics, Inc.(IOVA) | 3,041,685 | 3,041,685 | 0 | $28.56M | $22.51M | 3.49% | -$6.05M |
| eHealth, Inc.(EHTH) | 2,347,519 | 1,878,127 | -469,392 | $9.58M | $17.65M | 2.74% | +$8.08M |
| PTC Therapeutics, Inc.(PTCT) | 264,469 | 386,413 | +121,944 | $9.81M | $17.44M | 2.70% | +$7.63M |
| STAAR Surgical Company(STAA) | 1,091,608 | 500,775 | -590,833 | $40.55M | $12.16M | 1.88% | -$28.39M |
| Anaptysbio Inc | 843,971 | 843,971 | 0 | $28.27M | $11.17M | 1.73% | -$17.10M |
| Alkermes plcSHS(ALKS) | 384,656 | 289,308 | -95,348 | $10.77M | $8.32M | 1.29% | -$2.45M |
| Align Technology Inc | 37,772 | 37,772 | 0 | $9.61M | $7.88M | 1.22% | -$1.73M |
| Gossamer Bio, Inc.(GOSS) | 6,277,093 | 6,277,093 | 0 | $6.19M | $5.68M | 0.88% | -$513.5K |
| Acelyrin Inc | 1,792,895 | 1,792,895 | 0 | $8.84M | $5.63M | 0.87% | -$3.21M |
| Syndax Pharmaceuticals, Inc.(SNDX) | 405,193 | 405,193 | 0 | $7.80M | $5.36M | 0.83% | -$2.44M |
| Bicycle Therapeutics Plc-AdrADS | 59,582 | 248,934 | +189,352 | $1.35M | $3.49M | 0.54% | +$2.14M |
| Karyopharm Therapeutics Inc.(KPTI) | 5,102,193 | 4,907,001 | -195,192 | $4.23M | $3.32M | 0.51% | -$916.2K |
| Verve Therapeutics Inc | 575,817 | 575,817 | 0 | $2.79M | $3.25M | 0.50% | +$460.7K |
| Edwards Lifesciences Corp | 39,473 | 39,473 | 0 | $2.60M | $2.92M | 0.45% | +$317.4K |
| BioNTech SEADS(BNTX) | 25,206 | 25,206 | 0 | $2.99M | $2.87M | 0.45% | -$121.5K |
| Nevro Corp | 750,371 | 750,371 | 0 | $4.19M | $2.79M | 0.43% | -$1.40M |
| Mirum Pharmaceuticals, Inc.(MIRM) | 64,700 | 64,700 | 0 | $2.52M | $2.68M | 0.41% | +$152.0K |
| Nuvation Bio Inc.CL A(NUVB) | 772,652 | 772,652 | 0 | $1.77M | $2.06M | 0.32% | +$285.9K |
| Travere Therapeutics, Inc.(TVTX) | 110,719 | 110,719 | 0 | $1.55M | $1.93M | 0.30% | +$379.8K |
| Pyxis Oncology, Inc.(PYXS) | 170,000 | 1,037,421 | +867,421 | $623.9K | $1.62M | 0.25% | +$994.5K |
| Yarrow Bioscience Inc(YARW) | 445,434 | 445,434 | 0 | $837.4K | $1.49M | 0.23% | +$654.8K |
| Aclaris Therapeutics, Inc.(ACRS) | 569,832 | 569,832 | 0 | $655.3K | $1.41M | 0.22% | +$757.9K |
| Taysha Gene Therapies, Inc.(TSHA) | 811,268 | 811,268 | 0 | $1.63M | $1.40M | 0.22% | -$227.2K |
| Stoke Therapeutics, Inc.(STOK) | 125,861 | 125,861 | 0 | $1.55M | $1.39M | 0.22% | -$158.6K |
| Aldeyra Therapeutics, Inc.(ALDX) | 225,465 | 225,465 | 0 | $1.22M | $1.13M | 0.17% | -$90.2K |
| Humana Inc.(HUM) | 3,985 | 3,985 | 0 | $1.26M | $1.01M | 0.16% | -$251.2K |
| Jasper Therapeutics, Inc.(JSPR) | 0 | 30,651 | +30,651 | $0 | $655.3K | 0.10% | +$655.3K |
| Abeona Therapeutics Inc.(ABEO) | 12,865 | 108,865 | +96,000 | $81.3K | $606.4K | 0.09% | +$525.1K |
| UroGen Pharma Ltd.(URGN) | 24,500 | 24,500 | 0 | $311.1K | $260.9K | 0.04% | -$50.2K |
| Relmada Therapeutics, Inc.(RLMD) | 732,400 | 495,146 | -237,254 | $2.37M | $257.5K | 0.04% | -$2.12M |
| Instil Bio, Inc.(TIL) | 11,165 | 11,165 | 0 | $751.6K | $213.1K | 0.03% | -$538.5K |
| Akari Therapeutics, PlcADR(AKTX) | 0 | 146,024 | +146,024 | $0 | $178.1K | 0.03% | +$178.1K |
| Generation Bio Co | 150,475 | 150,475 | 0 | $371.7K | $159.5K | 0.02% | -$212.2K |
| Bluebird Bio Inc | 604,260 | 0 | -604,260 | $313.9K | $0 | — | -$313.9K |
| Elevation Oncology Inc | 1,298,097 | 0 | -1,298,097 | $778.7K | $0 | — | -$778.7K |
| Revance Therapeutics Inc | 1,611,787 | 0 | -1,611,787 | $8.37M | $0 | — | -$8.37M |
| Sage Therapeutics Inc | 1,010,833 | 0 | -1,010,833 | $7.30M | $0 | — | -$7.30M |