Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q1 2026 ▲▼ | Q2 2026 ▲▼ | Change ▲▼ | Q1 2026 ▲▼ | Q2 2026 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Ascendis Pharma A/S(ASND) | 0 | 10,281,496 | +10,281,496 | $0 | $2.74B | 23.83% | +$2.74B |
| Parabilis Medicines Inc | 0 | 28,933,371 | +28,933,371 | $0 | $791.91M | 6.88% | +$791.91M |
| Rhythm Pharmaceuticals, Inc.(RYTM) | 6,666,837 | 6,666,837 | 0 | $579.81M | $740.22M | 6.43% | +$160.40M |
| Vaxcyte, Inc.(PCVX) | 11,474,599 | 11,474,599 | 0 | $666.79M | $667.02M | 5.80% | +$229.5K |
| Sionna Therapeutics, Inc.(SION) | 9,905,045 | 9,905,045 | 0 | $397.09M | $435.72M | 3.79% | +$38.63M |
| Tyra Biosciences, Inc.(TYRA) | 12,198,625 | 12,198,625 | 0 | $467.21M | $389.62M | 3.39% | -$77.58M |
| Edgewise Therapeutics, Inc.(EWTX) | 10,428,437 | 8,392,730 | -2,035,707 | $328.50M | $341.00M | 2.96% | +$12.50M |
| Newamsterdam Pharma Co Nv ORDINARY SHARES | 9,550,191 | 9,550,191 | 0 | $305.70M | $323.66M | 2.81% | +$17.95M |
| Hemab Therapeutics Holdings | 0 | 7,808,627 | +7,808,627 | $0 | $286.81M | 2.49% | +$286.81M |
| Septerna, Inc.(SEPN) | 6,995,858 | 6,995,858 | 0 | $168.11M | $234.29M | 2.04% | +$66.18M |
| Bicara Therapeutics Inc | 7,255,993 | 7,255,993 | 0 | $144.32M | $215.43M | 1.87% | +$71.11M |
| Mineralys Therapeutics, Inc.(MLYS) | 7,692,750 | 7,692,750 | 0 | $208.40M | $207.55M | 1.80% | -$846.2K |
| GH Research PLC(GHRS) | 7,676,697 | 7,636,813 | -39,884 | $107.93M | $205.28M | 1.78% | +$97.34M |
| Disc Medicine, Inc.(IRON) | 2,450,221 | 2,450,221 | 0 | $156.67M | $179.21M | 1.56% | +$22.54M |
| SpyGlass Pharma, Inc.(SGP) | 8,021,117 | 8,021,117 | 0 | $207.83M | $178.55M | 1.55% | -$29.28M |
| Artiva Biotherapeutics, Inc.(ARTV) | 9,853,302 | 17,955,642 | +8,102,340 | $63.46M | $174.17M | 1.51% | +$110.71M |
| Janux Therapeutics, Inc.(JANX) | 11,189,693 | 11,189,693 | 0 | $155.54M | $171.87M | 1.49% | +$16.34M |
| Taysha Gene Therapies, Inc.(TSHA) | 23,555,648 | 23,555,648 | 0 | $105.29M | $160.41M | 1.39% | +$55.12M |
| BioCryst Pharmaceuticals, Inc.(BCRX) | 15,827,186 | 15,827,186 | 0 | $150.67M | $158.27M | 1.38% | +$7.60M |
| Wave Life Sciences, Inc.(WVE) | 26,975,505 | 26,975,505 | 0 | $195.57M | $156.73M | 1.36% | -$38.84M |
| Nuvalent Inc-A | 2,534,145 | 1,246,456 | -1,287,689 | $259.62M | $153.94M | 1.34% | -$105.69M |
| ABIVAX Société AnonymeADR(ABVX) | 0 | 1,132,557 | +1,132,557 | $0 | $150.92M | 1.31% | +$150.92M |
| Oruka Therapeutics, Inc.(ORKA) | 0 | 1,554,597 | +1,554,597 | $0 | $147.95M | 1.29% | +$147.95M |
| Climb Bio, Inc.(CLYM) | 11,300,939 | 11,300,939 | 0 | $77.41M | $147.36M | 1.28% | +$69.95M |
| Solid Biosciences Inc | 9,339,978 | 12,036,126 | +2,696,148 | $67.25M | $120.24M | 1.04% | +$52.99M |
| Zai Lab LimitedADR(ZLAB) | 5,707,262 | 5,743,533 | +36,271 | $107.35M | $109.13M | 0.95% | +$1.77M |
| ARS Pharmaceuticals, Inc.(SPRY) | 10,860,977 | 10,860,977 | 0 | $87.21M | $87.00M | 0.76% | -$217.2K |
| Xencor, Inc.(XNCR) | 4,897,237 | 5,274,274 | +377,037 | $59.06M | $84.92M | 0.74% | +$25.86M |
| Jade Biosciences Inc | 3,671,083 | 3,671,083 | 0 | $51.58M | $81.57M | 0.71% | +$29.99M |
| Intellia Therapeutics, Inc.(NTLA) | 0 | 4,526,926 | +4,526,926 | $0 | $76.60M | 0.67% | +$76.60M |
| LB Pharmaceuticals Inc(LBRX) | 2,208,604 | 2,208,604 | 0 | $54.46M | $71.68M | 0.62% | +$17.22M |
| Definium Therapeutics, Inc.(DFTX) | 0 | 1,500,000 | +1,500,000 | $0 | $70.56M | 0.61% | +$70.56M |
| Aclaris Therapeutics, Inc.(ACRS) | 6,804,072 | 12,723,026 | +5,918,954 | $25.52M | $67.30M | 0.58% | +$41.79M |
| 4d Molecular Therapeutics In | 5,049,779 | 5,049,779 | 0 | $47.01M | $67.16M | 0.58% | +$20.15M |
| Sana Biotechnology, Inc.(SANA) | 0 | 18,750,000 | +18,750,000 | $0 | $65.44M | 0.57% | +$65.44M |
| Damora Therapeutics, Inc.(DMRA) | 2,399,310 | 2,399,702 | +392 | $62.14M | $62.42M | 0.54% | +$274.1K |
| Monopar Therapeutics Inc.(MNPR) | 667,207 | 667,207 | 0 | $36.56M | $61.78M | 0.54% | +$25.22M |
| Acumen Pharmaceuticals, Inc.(ABOS) | 20,992,669 | 20,992,669 | 0 | $49.54M | $56.05M | 0.49% | +$6.51M |
| Geron Corporation(GERN) | 63,771,366 | 42,809,751 | -20,961,615 | $95.02M | $54.80M | 0.48% | -$40.22M |
| Rezolute, Inc.(RZLT) | 9,180,000 | 9,445,039 | +265,039 | $28.00M | $49.11M | 0.43% | +$21.12M |
| Evommune, Inc.(EVMN) | 3,494,638 | 3,494,638 | 0 | $80.34M | $46.44M | 0.40% | -$33.90M |
| Vor Biopharma Inc.(VOR) | 5,404,998 | 2,402,095 | -3,002,903 | $96.43M | $44.22M | 0.38% | -$52.20M |
| Century Therapeutics, Inc.(IPSC) | 17,754,430 | 17,754,430 | 0 | $40.13M | $43.50M | 0.38% | +$3.37M |
| Aktis Oncology, Inc.(AKTS) | 1,503,084 | 1,314,405 | -188,679 | $26.89M | $42.36M | 0.37% | +$15.47M |
| BioAge Labs, Inc.(BIOA) | 1,650,648 | 1,671,648 | +21,000 | $28.87M | $40.97M | 0.36% | +$12.10M |
| C4 Therapeutics, Inc.(CCCC) | 8,000,000 | 8,000,000 | 0 | $21.04M | $37.36M | 0.32% | +$16.32M |
| Mirum Pharmaceuticals, Inc.(MIRM) | 318,554 | 318,554 | 0 | $29.43M | $37.29M | 0.32% | +$7.87M |
| Capricor Therapeutics, Inc.(CAPR) | 1,507,844 | 1,507,844 | 0 | $45.84M | $36.31M | 0.32% | -$9.53M |
| PepGen Inc.(PEPG) | 20,064,545 | 20,064,545 | 0 | $35.51M | $36.12M | 0.31% | +$601.9K |
| Prelude Therapeutics Incorporated(PRLD) | 0 | 6,475,882 | +6,475,882 | $0 | $34.52M | 0.30% | +$34.52M |
| Nkarta, Inc.(NKTX) | 10,805,129 | 10,805,129 | 0 | $22.80M | $30.58M | 0.27% | +$7.78M |
| Q32 Bio Inc.(QTTB) | 0 | 2,332,457 | +2,332,457 | $0 | $29.72M | 0.26% | +$29.72M |
| Anteris Technologies Global Corp.(AVR) | 3,000,000 | 3,000,000 | 0 | $16.65M | $29.55M | 0.26% | +$12.90M |
| Editas Medicine, Inc.(EDIT) | 0 | 8,889,000 | +8,889,000 | $0 | $28.80M | 0.25% | +$28.80M |
| Ovid Therapeutics Inc.(OVID) | 10,714,000 | 10,500,968 | -213,032 | $23.79M | $28.25M | 0.25% | +$4.46M |
| Assembly Biosciences Inc | 1,020,410 | 1,020,410 | 0 | $28.32M | $28.04M | 0.24% | -$275.5K |
| ALX Oncology Holdings Inc.(ALXO) | 13,011,849 | 13,011,849 | 0 | $26.09M | $26.93M | 0.23% | +$845.8K |
| Benitec Biopharma Inc.(BNTC) | 1,850,000 | 1,850,000 | 0 | $19.70M | $24.75M | 0.22% | +$5.05M |
| LENZ Therapeutics, Inc.(LENZ) | 4,178,823 | 4,178,823 | 0 | $38.24M | $23.74M | 0.21% | -$14.50M |
| Lexeo Therapeutics, Inc.(LXEO) | 5,000,000 | 5,000,000 | 0 | $28.70M | $23.27M | 0.20% | -$5.42M |
| Acrivon Therapeutics Inc | 8,340,508 | 12,229,396 | +3,888,888 | $11.59M | $21.77M | 0.19% | +$10.18M |
| Altimmune, Inc.(ALT) | 0 | 6,500,000 | +6,500,000 | $0 | $19.76M | 0.17% | +$19.76M |
| Karyopharm Therapeutics Inc.(KPTI) | 1,917,354 | 1,917,354 | 0 | $10.68M | $18.73M | 0.16% | +$8.05M |
| Bright Minds Biosciences Inc.(DRUG) | 265,000 | 265,000 | 0 | $19.34M | $18.60M | 0.16% | -$734.0K |
| Avalo Therapeutics, Inc.(AVTX) | 662,968 | 1,000,000 | +337,032 | $9.90M | $18.48M | 0.16% | +$8.58M |
| OnKure Therapeutics, Inc.(OKUR) | 3,998,333 | 3,998,333 | 0 | $16.55M | $18.23M | 0.16% | +$1.68M |
| Faeth Therapeutics, Inc.(FTH) | 0 | 722,020 | +722,020 | $0 | $18.05M | 0.16% | +$18.05M |
| Aura Biosciences, Inc.(AURA) | 0 | 2,500,000 | +2,500,000 | $0 | $17.75M | 0.15% | +$17.75M |
| SAB Biotherapeutics, Inc.(SABS) | 4,401,500 | 4,401,500 | 0 | $16.86M | $17.17M | 0.15% | +$308.1K |
| Seaport Therapeutics Inc | 0 | 700,000 | +700,000 | $0 | $15.20M | 0.13% | +$15.20M |
| Palisade Bio, Inc.(PALI) | 7,124,116 | 7,124,116 | 0 | $12.47M | $14.89M | 0.13% | +$2.42M |
| Helix Acquisition Corp. III(HLXC) | 1,250,000 | 1,250,000 | 0 | $12.70M | $13.30M | 0.12% | +$600.0K |
| Waystar Holding Corp.(WAY) | 529,400 | 529,400 | 0 | $12.76M | $10.87M | 0.09% | -$1.90M |
| Equillium, Inc.(EQ) | 3,096,336 | 3,096,336 | 0 | $6.19M | $9.91M | 0.09% | +$3.72M |
| MacroGenics, Inc.(MGNX) | 1,864,176 | 1,864,176 | 0 | $5.39M | $8.61M | 0.07% | +$3.23M |
| Perceptive Capital Solutions CL A ORD SHS | 750,000 | 750,000 | 0 | $8.23M | $8.16M | 0.07% | -$67.5K |
| Adicet Bio Inc | 1,182,624 | 932,624 | -250,000 | $8.05M | $8.06M | 0.07% | +$4.2K |
| Newamsterdam Pharma Co Nv-27WTS *W EXP 99/99/999 | 333,333 | 333,333 | 0 | $6.68M | $7.12M | 0.06% | +$443.3K |
| Corvus Pharmaceuticals, Inc.(CRVS) | 450,000 | 450,000 | 0 | $6.58M | $6.72M | 0.06% | +$139.5K |
| Rani Therapeutics Holdings, Inc.(RANI) | 8,500,000 | 8,500,000 | 0 | $6.25M | $6.46M | 0.06% | +$217.6K |
| Jatt Ii Acquisition Corp | 0 | 500,000 | +500,000 | $0 | $5.68M | 0.05% | +$5.68M |
| Amanat Acquisition Corp Cl A | 0 | 375,000 | +375,000 | $0 | $3.81M | 0.03% | +$3.81M |
| Werewolf Therapeutics, Inc.(HOWL) | 6,681,307 | 2,387,744 | -4,293,563 | $5.56M | $859.3K | 0.01% | -$4.70M |
| Palatin Technologies, Inc.(PTN) | 70,000 | 62,124 | -7,876 | $1.22M | $670.3K | 0.01% | -$549.1K |
| Dianthus Therapeutics, Inc.(DNTH) | 2,611,733 | 0 | -2,611,733 | $219.18M | $0 | — | -$219.18M |
| Fulcrum Therapeutics, Inc.(FULC) | 6,053,960 | 0 | -6,053,960 | $46.43M | $0 | — | -$46.43M |
| GRAIL, Inc.(GRAL) | 428,266 | 0 | -428,266 | $22.13M | $0 | — | -$22.13M |
| Hinge Health, Inc.(HNGE) | 364,613 | 0 | -364,613 | $14.06M | $0 | — | -$14.06M |
| Inspire Medical Systems, Inc.(INSP) | 325,663 | 0 | -325,663 | $16.80M | $0 | — | -$16.80M |
| Sarepta Therapeutics, Inc.(SRPT) | 3,902,596 | 0 | -3,902,596 | $84.92M | $0 | — | -$84.92M |
| Sutro Biopharma, Inc.(STRO) | 715,307 | 0 | -715,307 | $17.82M | $0 | — | -$17.82M |
| Spyre Therapeutics, Inc.(SYRE) | 1,621,620 | 0 | -1,621,620 | $81.79M | $0 | — | -$81.79M |
| Ascendis Pharma A/SADR(ASND) | 10,281,496 | 0 | -10,281,496 | $2.35B | $0 | — | -$2.35B |
| Atrium Therapeutics, Inc.(RNA) | 864,102 | 0 | -864,102 | $11.55M | $0 | — | -$11.55M |
| Contineum Therapeutics, Inc.(CTNM) | 1,296,012 | 0 | -1,296,012 | $16.93M | $0 | — | -$16.93M |
| Design Therapeutics, Inc.(DSGN) | 2,972,973 | 0 | -2,972,973 | $31.63M | $0 | — | -$31.63M |
| MapLight Therapeutics, Inc.(MPLT) | 248,294 | 0 | -248,294 | $5.05M | $0 | — | -$5.05M |
| Olema Pharmaceuticals, Inc.(OLMA) | 2,600,000 | 0 | -2,600,000 | $38.77M | $0 | — | -$38.77M |
| Praxis Precision Medicines, Inc.(PRAX) | 373,787 | 0 | -373,787 | $120.43M | $0 | — | -$120.43M |
| Relmada Therapeutics, Inc.(RLMD) | 2,947,369 | 0 | -2,947,369 | $20.51M | $0 | — | -$20.51M |