Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q4 2023 ▲▼ | Q1 2024 ▲▼ | Change ▲▼ | Q4 2023 ▲▼ | Q1 2024 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Ascendis Pharma A/SSH(ASND) | 10,107,400 | 10,108,400 | +1,000 | $1.27B | $1.53B | 19.44% | +$255.06M |
| Vaxcyte, Inc.SH(PCVX) | 7,891,254 | 8,203,754 | +312,500 | $495.57M | $560.40M | 7.13% | +$64.83M |
| Legend Biotech CorporationSH(LEGN) | 6,264,707 | 6,861,097 | +596,390 | $376.95M | $384.84M | 4.90% | +$7.89M |
| Janux Therapeutics, Inc.SH(JANX) | 9,165,652 | 9,165,652 | 0 | $98.35M | $345.09M | 4.39% | +$246.74M |
| Aerovate Therapeutics IncSH | 8,263,982 | 8,263,982 | 0 | $187.01M | $244.37M | 3.11% | +$57.35M |
| Rhythm Pharmaceuticals, Inc.SH(RYTM) | 5,330,412 | 5,330,412 | 0 | $245.04M | $230.97M | 2.94% | -$14.07M |
| Evolent Health, Inc.SH(EVH) | 2,549,132 | 5,736,132 | +3,187,000 | $84.20M | $188.09M | 2.39% | +$103.89M |
| Newamsterdam Pharma Co NvSH ORDINARY SHARES | 7,864,000 | 7,864,000 | 0 | $87.84M | $185.98M | 2.37% | +$98.14M |
| RxSight, Inc.SH(RXST) | 3,404,285 | 3,442,825 | +38,540 | $137.26M | $177.58M | 2.26% | +$40.32M |
| Tyra Biosciences, Inc.SH(TYRA) | 7,236,454 | 10,416,609 | +3,180,155 | $100.22M | $170.83M | 2.17% | +$70.61M |
| Edgewise Therapeutics, Inc.SH(EWTX) | 0 | 8,909,091 | +8,909,091 | $0 | $162.50M | 2.07% | +$162.50M |
| 4d Molecular Therapeutics InSH | 4,163,211 | 5,051,511 | +888,300 | $84.35M | $160.94M | 2.05% | +$76.59M |
| Biogen Inc.SH(BIIB) | 532,892 | 740,727 | +207,835 | $137.90M | $159.72M | 2.03% | +$21.83M |
| PepGen Inc.SH(PEPG) | 8,131,952 | 10,689,545 | +2,557,593 | $55.30M | $157.14M | 2.00% | +$101.84M |
| Geron CorporationSH(GERN) | 46,202,425 | 46,202,425 | 0 | $97.49M | $152.47M | 1.94% | +$54.98M |
| 89bio IncSH | 11,416,948 | 12,766,948 | +1,350,000 | $127.53M | $148.61M | 1.89% | +$21.08M |
| Dyne Therapeutics, Inc.SH(DYN) | 0 | 4,954,779 | +4,954,779 | $0 | $140.67M | 1.79% | +$140.67M |
| Apogee Therapeutics IncSH | 1,977,901 | 1,977,901 | 0 | $55.26M | $131.43M | 1.67% | +$76.17M |
| Day One Biopharmaceuticals ISH COM | 7,809,852 | 7,809,852 | 0 | $114.02M | $129.02M | 1.64% | +$14.99M |
| Nkarta, Inc.SH(NKTX) | 7,805,129 | 10,805,129 | +3,000,000 | $51.51M | $116.80M | 1.49% | +$65.29M |
| Wave Life Sciences, Inc.SH(WVE) | 18,202,009 | 18,202,009 | 0 | $91.92M | $112.31M | 1.43% | +$20.39M |
| ARS Pharmaceuticals, Inc.SH(SPRY) | 9,459,678 | 10,860,977 | +1,401,299 | $51.84M | $111.00M | 1.41% | +$59.16M |
| Fulcrum Therapeutics, Inc.SH(FULC) | 11,609,704 | 11,609,704 | 0 | $78.37M | $109.60M | 1.39% | +$31.23M |
| Verona Pharma Plc - AdrSH | 6,317,990 | 6,317,990 | 0 | $125.60M | $101.66M | 1.29% | -$23.95M |
| LENZ Therapeutics, Inc.SH(LENZ) | 0 | 4,178,823 | +4,178,823 | $0 | $93.31M | 1.19% | +$93.31M |
| Inhibrx IncSH | 4,724,207 | 2,629,837 | -2,094,370 | $179.52M | $91.94M | 1.17% | -$87.58M |
| Avidity Biosciences IncSH | 2,454,533 | 3,282,180 | +827,647 | $22.21M | $83.76M | 1.07% | +$61.55M |
| Axsome Therapeutics, Inc.SH(AXSM) | 1,000,000 | 1,000,000 | 0 | $79.59M | $79.80M | 1.02% | +$210.0K |
| Longboard Pharmaceuticals InSH | 0 | 3,289,119 | +3,289,119 | $0 | $71.04M | 0.90% | +$71.04M |
| Dianthus Therapeutics, Inc.SH(DNTH) | 0 | 2,333,000 | +2,333,000 | $0 | $69.99M | 0.89% | +$69.99M |
| GH Research PLCSH(GHRS) | 5,587,333 | 6,251,714 | +664,381 | $32.41M | $66.64M | 0.85% | +$34.24M |
| Structure Therapeutics IncSH | 486,832 | 1,510,362 | +1,023,530 | $19.84M | $64.73M | 0.82% | +$44.89M |
| Mineralys Therapeutics, Inc.SH(MLYS) | 3,178,476 | 4,850,984 | +1,672,508 | $27.33M | $62.63M | 0.80% | +$35.29M |
| Astria Therapeutics IncSH | 0 | 4,413,150 | +4,413,150 | $0 | $62.12M | 0.79% | +$62.12M |
| CG Oncology, Inc.SH(CGON) | 0 | 1,397,433 | +1,397,433 | $0 | $61.35M | 0.78% | +$61.35M |
| Acumen Pharmaceuticals, Inc.SH(ABOS) | 14,932,063 | 14,932,063 | 0 | $57.34M | $60.47M | 0.77% | +$3.14M |
| Iteos Therapeutics IncSH | 4,417,259 | 4,417,259 | 0 | $48.37M | $60.25M | 0.77% | +$11.88M |
| Solid Biosciences IncSH | 3,426,286 | 4,330,446 | +904,160 | $21.04M | $57.68M | 0.73% | +$36.64M |
| Madrigal Pharmaceuticals, Inc.SH(MDGL) | 204,500 | 204,500 | 0 | $47.32M | $54.61M | 0.69% | +$7.29M |
| Vor Biopharma Inc.SH(VOR) | 22,748,880 | 22,748,880 | 0 | $51.18M | $53.91M | 0.69% | +$2.73M |
| Praxis Precision Medicines, Inc.SH(PRAX) | 0 | 828,380 | +828,380 | $0 | $50.55M | 0.64% | +$50.55M |
| UroGen Pharma Ltd.SH(URGN) | 3,083,430 | 3,083,430 | 0 | $46.25M | $46.25M | 0.59% | $0 |
| Larimar Therapeutics, Inc.SH(LRMR) | 0 | 6,045,351 | +6,045,351 | $0 | $45.88M | 0.58% | +$45.88M |
| Cytek Biosciences, Inc.SH(CTKB) | 6,809,404 | 6,809,404 | 0 | $62.10M | $45.69M | 0.58% | -$16.41M |
| C4 Therapeutics, Inc.SH(CCCC) | 4,878,000 | 4,878,000 | 0 | $27.56M | $39.85M | 0.51% | +$12.29M |
| Werewolf Therapeutics, Inc.SH(HOWL) | 6,144,881 | 6,144,881 | 0 | $23.72M | $39.82M | 0.51% | +$16.10M |
| Enliven Therapeutics IncSH | 2,122,465 | 2,122,465 | 0 | $29.37M | $37.33M | 0.47% | +$7.96M |
| Climb Bio, Inc.SH(CLYM) | 13,150,849 | 13,150,849 | 0 | $35.51M | $36.03M | 0.46% | +$526.0K |
| Acrivon Therapeutics IncSH | 4,810,508 | 4,810,508 | 0 | $23.67M | $34.40M | 0.44% | +$10.73M |
| Taysha Gene Therapies, Inc.SH(TSHA) | 18,472,503 | 10,872,503 | -7,600,000 | $32.70M | $31.20M | 0.40% | -$1.49M |
| Boundless Bio, Inc.SH(BOLD) | 0 | 2,180,631 | +2,180,631 | $0 | $31.07M | 0.40% | +$31.07M |
| MacroGenics, Inc.SH(MGNX) | 4,053,077 | 2,082,021 | -1,971,056 | $38.99M | $30.65M | 0.39% | -$8.34M |
| Tenaya Therapeutics, Inc.SH(TNYA) | 5,507,347 | 5,755,050 | +247,703 | $17.84M | $30.10M | 0.38% | +$12.26M |
| Cybin D/B/A Helus PharmaSH(HELP) | 0 | 58,139,535 | +58,139,535 | $0 | $24.04M | 0.31% | +$24.04M |
| Alto Neuroscience, Inc.SH(ANRO) | 0 | 1,385,491 | +1,385,491 | $0 | $21.27M | 0.27% | +$21.27M |
| CervoMed Inc.SH(CRVO) | 0 | 861,573 | +861,573 | $0 | $20.07M | 0.26% | +$20.07M |
| Vaxart, Inc.SH(VXRT) | 0 | 15,384,615 | +15,384,615 | $0 | $20.00M | 0.25% | +$20.00M |
| Bicycle Therapeutics Plc-AdrSH | 800,000 | 800,000 | 0 | $14.46M | $19.92M | 0.25% | +$5.46M |
| EyePoint, Inc.SH(EYPT) | 0 | 938,591 | +938,591 | $0 | $19.40M | 0.25% | +$19.40M |
| Third Harmonic Bio IncSH | 2,033,056 | 2,033,056 | 0 | $22.30M | $19.19M | 0.24% | -$3.11M |
| Pliant Therapeutics, Inc.SH(PLRX) | 1,281,000 | 1,281,000 | 0 | $23.20M | $19.09M | 0.24% | -$4.11M |
| Sera Prognostics, Inc.SH(SERA) | 0 | 2,024,221 | +2,024,221 | $0 | $18.42M | 0.23% | +$18.42M |
| Metagenomi Therapeutics, Inc.SH(MGX) | 0 | 1,744,415 | +1,744,415 | $0 | $18.40M | 0.23% | +$18.40M |
| Immatics N.V.SH(IMTX) | 0 | 1,750,000 | +1,750,000 | $0 | $18.39M | 0.23% | +$18.39M |
| An2 Therapeutics IncSH | 5,551,295 | 5,551,295 | 0 | $113.75M | $18.04M | 0.23% | -$95.70M |
| Regulus Therapeutics IncSH | 0 | 6,250,000 | +6,250,000 | $0 | $18.00M | 0.23% | +$18.00M |
| Black Diamond Therapeutics ISH | 3,525,754 | 3,525,754 | 0 | $9.91M | $17.88M | 0.23% | +$7.97M |
| Adicet Bio IncSH | 0 | 7,541,000 | +7,541,000 | $0 | $17.72M | 0.23% | +$17.72M |
| Arvinas, Inc.SH(ARVN) | 421,348 | 421,348 | 0 | $17.34M | $17.39M | 0.22% | +$50.6K |
| Lexeo Therapeutics, Inc.SH(LXEO) | 0 | 660,938 | +660,938 | $0 | $10.36M | 0.13% | +$10.36M |
| Chimerix IncSH | 8,800,000 | 8,800,000 | 0 | $8.47M | $9.33M | 0.12% | +$858.0K |
| Igm Biosciences IncSH | 937,500 | 937,500 | 0 | $7.79M | $9.05M | 0.12% | +$1.26M |
| COMPASS Pathways plcSH(CMPS) | 1,286,000 | 791,359 | -494,641 | $11.25M | $6.58M | 0.08% | -$4.67M |
| Curevac NvSH | 2,744,270 | 1,965,707 | -778,563 | $11.55M | $5.96M | 0.08% | -$5.60M |
| Unicycive Therapeutics IncSH | 3,470,688 | 3,470,688 | 0 | $3.01M | $4.79M | 0.06% | +$1.78M |
| Newamsterdam Pharma Co Nv-27SH *W EXP 99/99/999 | 333,333 | 333,333 | 0 | $1.04M | $3.68M | 0.05% | +$2.64M |
| Alpine Immune Sciences IncSH | 4,909,763 | 0 | -4,909,763 | $93.58M | $0 | — | -$93.58M |
| Connect Biopharma Holdings LSH | 3,062,871 | 0 | -3,062,871 | $3.61M | $0 | — | -$3.61M |
| Cymabay Therapeutics IncSH | 6,940,000 | 0 | -6,940,000 | $163.92M | $0 | — | -$163.92M |
| Icosavax IncSH | 5,963,565 | 0 | -5,963,565 | $93.99M | $0 | — | -$93.99M |
| Immunogen IncSH | 23,750,601 | 0 | -23,750,601 | $704.21M | $0 | — | -$704.21M |
| Harpoon Therapeutics IncSH | 1,500,000 | 0 | -1,500,000 | $17.05M | $0 | — | -$17.05M |
| SAB Biotherapeutics, Inc.SH(SABS) | 2,374,081 | 0 | -2,374,081 | $1.63M | $0 | — | -$1.63M |