Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q1 2024 ▲▼ | Q2 2024 ▲▼ | Change ▲▼ | Q1 2024 ▲▼ | Q2 2024 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Ascendis Pharma A/SSH(ASND) | 10,108,400 | 10,108,400 | 0 | $1.53B | $1.38B | 18.23% | -$149.50M |
| Vaxcyte, Inc.SH(PCVX) | 8,203,754 | 8,203,754 | 0 | $560.40M | $619.47M | 8.19% | +$59.07M |
| Janux Therapeutics, Inc.SH(JANX) | 9,165,652 | 9,165,652 | 0 | $345.09M | $383.95M | 5.08% | +$38.86M |
| Legend Biotech CorporationSH(LEGN) | 6,861,097 | 7,506,934 | +645,837 | $384.84M | $332.48M | 4.40% | -$52.36M |
| Rhythm Pharmaceuticals, Inc.SH(RYTM) | 5,330,412 | 6,084,412 | +754,000 | $230.97M | $249.83M | 3.30% | +$18.86M |
| Biogen Inc.SH(BIIB) | 740,727 | 982,139 | +241,412 | $159.72M | $227.68M | 3.01% | +$67.96M |
| Climb Bio, Inc.SH(CLYM) | 13,150,849 | 31,419,267 | +18,268,418 | $36.03M | $223.39M | 2.95% | +$187.36M |
| RxSight, Inc.SH(RXST) | 3,442,825 | 3,694,825 | +252,000 | $177.58M | $222.32M | 2.94% | +$44.74M |
| Avidity Biosciences IncSH | 3,282,180 | 5,400,408 | +2,118,228 | $83.76M | $220.61M | 2.92% | +$136.85M |
| Dyne Therapeutics, Inc.SH(DYN) | 4,954,779 | 6,049,204 | +1,094,425 | $140.67M | $213.48M | 2.82% | +$72.81M |
| Geron CorporationSH(GERN) | 46,202,425 | 46,202,425 | 0 | $152.47M | $195.90M | 2.59% | +$43.43M |
| PepGen Inc.SH(PEPG) | 10,689,545 | 10,689,545 | 0 | $157.14M | $170.61M | 2.26% | +$13.47M |
| Tyra Biosciences, Inc.SH(TYRA) | 10,416,609 | 10,416,609 | 0 | $170.83M | $166.56M | 2.20% | -$4.27M |
| Evolent Health, Inc.SH(EVH) | 5,736,132 | 8,514,862 | +2,778,730 | $188.09M | $162.80M | 2.15% | -$25.28M |
| Edgewise Therapeutics, Inc.SH(EWTX) | 8,909,091 | 8,909,091 | 0 | $162.50M | $160.45M | 2.12% | -$2.05M |
| Newamsterdam Pharma Co NvSH ORDINARY SHARES | 7,864,000 | 8,064,000 | +200,000 | $185.98M | $154.91M | 2.05% | -$31.07M |
| Recursion Pharmaceuticals, Inc.SH(RXRX) | 0 | 15,384,615 | +15,384,615 | $0 | $115.38M | 1.53% | +$115.38M |
| 89bio IncSH | 12,766,948 | 14,175,398 | +1,408,450 | $148.61M | $113.54M | 1.50% | -$35.06M |
| Verona Pharma Plc - AdrSH | 6,317,990 | 7,632,646 | +1,314,656 | $101.66M | $110.37M | 1.46% | +$8.71M |
| Day One Biopharmaceuticals ISH COM | 7,809,852 | 7,871,721 | +61,869 | $129.02M | $108.47M | 1.43% | -$20.55M |
| 4d Molecular Therapeutics InSH | 5,051,511 | 5,098,211 | +46,700 | $160.94M | $107.01M | 1.42% | -$53.93M |
| ARS Pharmaceuticals, Inc.SH(SPRY) | 10,860,977 | 10,860,977 | 0 | $111.00M | $92.43M | 1.22% | -$18.57M |
| Wave Life Sciences, Inc.SH(WVE) | 18,202,009 | 18,202,009 | 0 | $112.31M | $90.83M | 1.20% | -$21.48M |
| Longboard Pharmaceuticals InSH | 3,289,119 | 3,289,119 | 0 | $71.04M | $88.90M | 1.18% | +$17.86M |
| Arcellx IncSH COMMON STOCK | 0 | 1,604,014 | +1,604,014 | $0 | $88.53M | 1.17% | +$88.53M |
| Axsome Therapeutics, Inc.SH(AXSM) | 1,000,000 | 1,000,000 | 0 | $79.80M | $80.50M | 1.06% | +$700.0K |
| Apogee Therapeutics IncSH | 1,977,901 | 1,961,863 | -16,038 | $131.43M | $77.20M | 1.02% | -$54.23M |
| GH Research PLCSH(GHRS) | 6,251,714 | 6,601,689 | +349,975 | $66.64M | $76.98M | 1.02% | +$10.33M |
| Structure Therapeutics IncSH | 1,510,362 | 1,896,772 | +386,410 | $64.73M | $74.49M | 0.99% | +$9.75M |
| LENZ Therapeutics, Inc.SH(LENZ) | 4,178,823 | 4,178,823 | 0 | $93.31M | $72.25M | 0.96% | -$21.06M |
| Fulcrum Therapeutics, Inc.SH(FULC) | 11,609,704 | 11,609,704 | 0 | $109.60M | $71.98M | 0.95% | -$37.62M |
| Nkarta, Inc.SH(NKTX) | 10,805,129 | 10,805,129 | 0 | $116.80M | $63.86M | 0.84% | -$52.95M |
| Dianthus Therapeutics, Inc.SH(DNTH) | 2,333,000 | 2,333,000 | 0 | $69.99M | $60.38M | 0.80% | -$9.61M |
| Mineralys Therapeutics, Inc.SH(MLYS) | 4,850,984 | 4,850,984 | 0 | $62.63M | $56.76M | 0.75% | -$5.87M |
| Iteos Therapeutics IncSH | 4,417,259 | 3,517,259 | -900,000 | $60.25M | $52.20M | 0.69% | -$8.06M |
| UroGen Pharma Ltd.SH(URGN) | 3,083,430 | 3,083,430 | 0 | $46.25M | $51.74M | 0.68% | +$5.49M |
| Praxis Precision Medicines, Inc.SH(PRAX) | 828,380 | 1,235,599 | +407,219 | $50.55M | $51.10M | 0.68% | +$556.6K |
| Enliven Therapeutics IncSH | 2,122,465 | 2,122,465 | 0 | $37.33M | $49.60M | 0.66% | +$12.27M |
| Acrivon Therapeutics IncSH | 4,810,508 | 8,340,508 | +3,530,000 | $34.40M | $48.37M | 0.64% | +$13.98M |
| Astria Therapeutics IncSH | 4,413,150 | 5,043,756 | +630,606 | $62.12M | $45.90M | 0.61% | -$16.22M |
| Bicycle Therapeutics Plc-AdrSH | 800,000 | 2,253,000 | +1,453,000 | $19.92M | $45.60M | 0.60% | +$25.68M |
| CG Oncology, Inc.SH(CGON) | 1,397,433 | 1,397,433 | 0 | $61.35M | $44.12M | 0.58% | -$17.23M |
| Larimar Therapeutics, Inc.SH(LRMR) | 6,045,351 | 6,045,351 | 0 | $45.88M | $43.83M | 0.58% | -$2.06M |
| Acumen Pharmaceuticals, Inc.SH(ABOS) | 14,932,063 | 14,932,063 | 0 | $60.47M | $36.14M | 0.48% | -$24.34M |
| Tourmaline Bio IncSH | 0 | 2,538,925 | +2,538,925 | $0 | $32.65M | 0.43% | +$32.65M |
| Third Harmonic Bio IncSH | 2,033,056 | 2,033,056 | 0 | $19.19M | $26.43M | 0.35% | +$7.24M |
| Solid Biosciences IncSH | 4,330,446 | 4,330,446 | 0 | $57.68M | $24.55M | 0.32% | -$33.13M |
| Taysha Gene Therapies, Inc.SH(TSHA) | 10,872,503 | 10,872,503 | 0 | $31.20M | $24.35M | 0.32% | -$6.85M |
| Tenaya Therapeutics, Inc.SH(TNYA) | 5,755,050 | 7,622,347 | +1,867,297 | $30.10M | $23.63M | 0.31% | -$6.47M |
| Vor Biopharma Inc.SH(VOR) | 22,748,880 | 22,748,880 | 0 | $53.91M | $22.75M | 0.30% | -$31.17M |
| C4 Therapeutics, Inc.SH(CCCC) | 4,878,000 | 4,878,000 | 0 | $39.85M | $22.54M | 0.30% | -$17.32M |
| Alto Neuroscience, Inc.SH(ANRO) | 1,385,491 | 2,085,554 | +700,063 | $21.27M | $22.29M | 0.29% | +$1.03M |
| Immatics N.V.SH(IMTX) | 1,750,000 | 1,750,000 | 0 | $18.39M | $20.34M | 0.27% | +$1.94M |
| Sera Prognostics, Inc.SH(SERA) | 2,024,221 | 3,032,808 | +1,008,587 | $18.42M | $17.95M | 0.24% | -$466.2K |
| Aerovate Therapeutics IncSH | 8,263,982 | 9,192,092 | +928,110 | $244.37M | $15.26M | 0.20% | -$229.11M |
| Werewolf Therapeutics, Inc.SH(HOWL) | 6,144,881 | 6,144,881 | 0 | $39.82M | $14.99M | 0.20% | -$24.83M |
| CervoMed Inc.SH(CRVO) | 861,573 | 817,120 | -44,453 | $20.07M | $13.99M | 0.19% | -$6.09M |
| Pliant Therapeutics, Inc.SH(PLRX) | 1,281,000 | 1,281,000 | 0 | $19.09M | $13.77M | 0.18% | -$5.32M |
| Nurix Therapeutics, Inc.SH(NRIX) | 0 | 650,000 | +650,000 | $0 | $13.57M | 0.18% | +$13.57M |
| Insmed IncorporatedSH(INSM) | 0 | 200,000 | +200,000 | $0 | $13.40M | 0.18% | +$13.40M |
| An2 Therapeutics IncSH | 5,551,295 | 5,551,295 | 0 | $18.04M | $11.94M | 0.16% | -$6.11M |
| Cybin D/B/A Helus PharmaSH(HELP) | 58,139,535 | 44,004,464 | -14,135,071 | $24.04M | $11.93M | 0.16% | -$12.12M |
| Zura Bio LimitedSH(ZURA) | 0 | 3,217,503 | +3,217,503 | $0 | $11.26M | 0.15% | +$11.26M |
| Arvinas, Inc.SH(ARVN) | 421,348 | 421,348 | 0 | $17.39M | $11.22M | 0.15% | -$6.18M |
| Regulus Therapeutics IncSH | 6,250,000 | 6,250,000 | 0 | $18.00M | $11.16M | 0.15% | -$6.84M |
| Lexeo Therapeutics, Inc.SH(LXEO) | 660,938 | 672,712 | +11,774 | $10.36M | $10.79M | 0.14% | +$426.8K |
| Adicet Bio IncSH | 7,541,000 | 7,541,000 | 0 | $17.72M | $9.12M | 0.12% | -$8.60M |
| Nuvalent Inc-ASH | 0 | 119,789 | +119,789 | $0 | $9.09M | 0.12% | +$9.09M |
| MacroGenics, Inc.SH(MGNX) | 2,082,021 | 2,082,021 | 0 | $30.65M | $8.85M | 0.12% | -$21.80M |
| Boundless Bio, Inc.SH(BOLD) | 2,180,631 | 2,180,631 | 0 | $31.07M | $8.44M | 0.11% | -$22.63M |
| Chimerix IncSH | 8,800,000 | 8,800,000 | 0 | $9.33M | $7.71M | 0.10% | -$1.62M |
| Perceptive Capital SolutionsSH CL A ORD SHS | 0 | 750,000 | +750,000 | $0 | $7.54M | 0.10% | +$7.54M |
| Metagenomi Therapeutics, Inc.SH(MGX) | 1,744,415 | 1,477,749 | -266,666 | $18.40M | $6.03M | 0.08% | -$12.37M |
| Protara Therapeutics, Inc.SH(TARA) | 0 | 1,900,000 | +1,900,000 | $0 | $3.95M | 0.05% | +$3.95M |
| Surrozen, Inc.SH(SRZN) | 0 | 282,580 | +282,580 | $0 | $3.09M | 0.04% | +$3.09M |
| Newamsterdam Pharma Co Nv-27SH *W EXP 99/99/999 | 333,333 | 333,333 | 0 | $3.68M | $2.91M | 0.04% | -$773.3K |
| Unicycive Therapeutics IncSH | 3,470,688 | 2,632,200 | -838,488 | $4.79M | $1.32M | 0.02% | -$3.47M |
| Scilex Holding CompanySH(SCLX) | 0 | 261,179 | +261,179 | $0 | $504.1K | 0.01% | +$504.1K |
| Black Diamond Therapeutics ISH | 3,525,754 | 0 | -3,525,754 | $17.88M | $0 | — | -$17.88M |
| COMPASS Pathways plcSH(CMPS) | 791,359 | 0 | -791,359 | $6.58M | $0 | — | -$6.58M |
| Curevac NvSH | 1,965,707 | 0 | -1,965,707 | $5.96M | $0 | — | -$5.96M |
| Cytek Biosciences, Inc.SH(CTKB) | 6,809,404 | 0 | -6,809,404 | $45.69M | $0 | — | -$45.69M |
| EyePoint, Inc.SH(EYPT) | 938,591 | 0 | -938,591 | $19.40M | $0 | — | -$19.40M |
| Igm Biosciences IncSH | 937,500 | 0 | -937,500 | $9.05M | $0 | — | -$9.05M |
| Inhibrx IncSH | 2,629,837 | 0 | -2,629,837 | $91.94M | $0 | — | -$91.94M |
| Madrigal Pharmaceuticals, Inc.SH(MDGL) | 204,500 | 0 | -204,500 | $54.61M | $0 | — | -$54.61M |
| Vaxart, Inc.SH(VXRT) | 15,384,615 | 0 | -15,384,615 | $20.00M | $0 | — | -$20.00M |