Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q4 2025 ▲▼ | Q1 2026 ▲▼ | Change ▲▼ | Q4 2025 ▲▼ | Q1 2026 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| DAY ONE BIOPHARMACEUTICALS I COM | 999,163 | 978,463 | -20,700 | 9,312 | 20,978 | 4.77% | +11,666 |
| NEKTAR THERAPEUTICS(NKTR) | 74,998 | 165,178 | +90,180 | 3,171 | 11,885 | 2.70% | +8,714 |
| REVOLUTION MEDICINES INC(RVMD) | 604,514 | 580,678 | -23,836 | 48,150 | 56,471 | 12.85% | +8,321 |
| COMPASS PATHWAYS PLC(CMPS) | 811,046 | 2,418,882 | +1,607,836 | 5,596 | 13,376 | 3.04% | +7,780 |
| LARIMAR THERAPEUTICS INC(LRMR) | 939,164 | 2,029,164 | +1,090,000 | 3,578 | 9,131 | 2.08% | +5,553 |
| BICARA THERAPEUTICS INC | 261,583 | 421,733 | +160,150 | 4,402 | 8,388 | 1.91% | +3,986 |
| CENTURY THERAPEUTICS INC(IPSC) | 2,793,586 | 2,434,353 | -359,233 | 2,779 | 5,502 | 1.25% | +2,723 |
| XENON PHARMACEUTICALS INC(XENE) | 287,939 | 250,772 | -37,167 | 12,905 | 14,582 | 3.32% | +1,677 |
| FULCRUM THERAPEUTICS INC(FULC) | 0 | 205,000 | +205,000 | 0 | 1,572 | 0.36% | +1,572 |
| ORTHOPEDIATRICS CORP(KIDS) | 0 | 95,659 | +95,659 | 0 | 1,518 | 0.35% | +1,518 |
| ALLOGENE THERAPEUTICS INC | 1,380,118 | 1,370,118 | -10,000 | 1,891 | 3,343 | 0.76% | +1,452 |
| ALKERMES PLC(ALKS) | 130,248 | 139,482 | +9,234 | 3,644 | 4,932 | 1.12% | +1,288 |
| CYTOMX THERAPEUTICS INC(CTMX) | 0 | 230,000 | +230,000 | 0 | 1,081 | 0.25% | +1,081 |
| MAZE THERAPEUTICS INC(MAZE) | 0 | 35,000 | +35,000 | 0 | 1,045 | 0.24% | +1,045 |
| SCYNEXIS INC(SCYX) | 0 | 1,086,956 | +1,086,956 | 0 | 997 | 0.23% | +997 |
| MAPLIGHT THERAPEUTICS INC(MPLT) | 143,764 | 171,006 | +27,242 | 2,525 | 3,477 | 0.79% | +951 |
| ULTRAGENYX PHARMACEUTICAL INC(RARE) | 16,000 | 61,100 | +45,100 | 368 | 1,280 | 0.29% | +912 |
| DENALI THERAPEUTICS INC(DNLI) | 318,500 | 318,500 | 0 | 5,258 | 6,115 | 1.39% | +857 |
| BIOCRYST PHARMACEUTICALS INC(BCRX) | 418,255 | 430,248 | +11,993 | 3,262 | 4,096 | 0.93% | +834 |
| ZENAS BIOPHARMA INC(ZBIO) | 0 | 42,500 | +42,500 | 0 | 831 | 0.19% | +831 |
| STOKE THERAPEUTICS INC(STOK) | 108,875 | 130,875 | +22,000 | 3,456 | 4,261 | 0.97% | +806 |
| NEWAMSTERDAM PHARMA CO ORDINARY SHARES | 0 | 20,000 | +20,000 | 0 | 640 | 0.15% | +640 |
| PLIANT THERAPEUTICS INC(PLRX) | 0 | 487,000 | +487,000 | 0 | 614 | 0.14% | +614 |
| NEUROGENE INC(NGNE) | 27,974 | 56,635 | +28,661 | 576 | 1,142 | 0.26% | +565 |
| ALECTOR INC | 908,351 | 908,351 | 0 | 1,417 | 1,953 | 0.44% | +536 |
| ASCENDIS PHARMA A/S(ASND) | 0 | 0 | 0 | 5,460 | 5,917 | 1.35% | +457 |
| IBIO INC(IBIO) | 0 | 193,638 | +193,638 | 0 | 368 | 0.08% | +368 |
| INSULET CORP(PODD) | 6,870 | 10,870 | +4,000 | 1,953 | 2,281 | 0.52% | +328 |
| CELLDEX THERAPEUTICS INC(CLDX) | 68,518 | 68,518 | 0 | 1,861 | 2,173 | 0.49% | +312 |
| INSPIRE MEDICAL SYSTEMS INC(INSP) | 8,600 | 18,200 | +9,600 | 793 | 939 | 0.21% | +146 |
| NEUMORA THERAPEUTICS INC(NMRA) | 0 | 70,000 | +70,000 | 0 | 137 | 0.03% | +137 |
| COMPUGEN LTD(CGEN) | 272,402 | 257,783 | -14,619 | 417 | 549 | 0.12% | +132 |
| FATE THERAPEUTICS INC(FATE) | 550,000 | 550,000 | 0 | 540 | 660 | 0.15% | +120 |
| ALIGN TECHNOLOGY INC | 16,000 | 15,000 | -1,000 | 2,498 | 2,571 | 0.58% | +73 |
| RAPPORT THERAPEUTICS INC(RAPP) | 75,000 | 75,000 | 0 | 2,276 | 2,347 | 0.53% | +71 |
| MBX BIOSCIENCES INC(MBX) | 165,265 | 175,465 | +10,200 | 5,212 | 5,238 | 1.19% | +25 |
| ORCHESTRA BIOMED HOLDINGS INC(OBIO) | 126,841 | 126,841 | 0 | 526 | 539 | 0.12% | +13 |
| POLYPID LTD(PYPD) | 207,900 | 207,900 | 0 | 902 | 911 | 0.21% | +8 |
| ADC THERAPEUTICS SA(ADCT) | 77,081 | 72,081 | -5,000 | 272 | 270 | 0.06% | -2 |
| BIONTECH SE(BNTX) | 7,000 | 7,000 | 0 | 666 | 622 | 0.14% | -44 |
| IMMUNOVANT INC(IMVT) | 150,524 | 150,524 | 0 | 3,826 | 3,739 | 0.85% | -87 |
| AUTOLUS THERAPEUTICS LTD(AUTL) | 179,316 | 179,316 | 0 | 357 | 247 | 0.06% | -109 |
| KARYOPHARM THERAPEUTICS INC(KPTI) | 51,000 | 45,800 | -5,200 | 375 | 255 | 0.06% | -120 |
| PERSPECTIVE THERAPEUTICS INC(CATX) | 50,000 | 0 | -50,000 | 138 | 0 | — | -137 |
| FOGHORN THERAPEUTICS INC(FHTX) | 126,859 | 111,859 | -15,000 | 685 | 535 | 0.12% | -150 |
| ADICET BIO INC | 93,812 | 93,812 | 0 | 790 | 639 | 0.15% | -151 |
| VIKING THERAPEUTICS INC(VKTX) | 59,516 | 59,516 | 0 | 2,094 | 1,937 | 0.44% | -157 |
| BICYCLE THERAPEUTICS PLC | 64,492 | 64,492 | 0 | 457 | 299 | 0.07% | -157 |
| ENGENE HOLDINGS INC COM | 163,645 | 187,353 | +23,708 | 1,478 | 1,276 | 0.29% | -202 |
| ORIC PHARMACEUTICALS INC(ORIC) | 141,045 | 98,724 | -42,321 | 1,154 | 945 | 0.22% | -208 |
| BRAINSWAY LTD(BWAY) | 12,965 | 0 | -12,965 | 247 | 0 | — | -247 |
| STRUCTURE THERAPEUTICS INC | 37,000 | 46,500 | +9,500 | 2,573 | 2,241 | 0.51% | -332 |
| INOGEN INC(INGN) | 827,071 | 845,179 | +18,108 | 5,558 | 5,223 | 1.19% | -335 |
| SPDR S&P BIOTECH ETF ST STR SP BIOT | 336,505 | 318,505 | -18,000 | 41,030 | 40,683 | 9.25% | -347 |
| GALAPAGOS NV(LKFT) | 130,175 | 130,175 | 0 | 4,257 | 3,905 | 0.89% | -351 |
| MINERALYS THERAPEUTICS INC(MLYS) | 38,490 | 38,490 | 0 | 1,397 | 1,043 | 0.24% | -354 |
| KALVISTA PHARMACEUTICALS INC | 356,802 | 267,402 | -89,400 | 5,762 | 5,383 | 1.22% | -380 |
| EDGEWISE THERAPEUTICS INC(EWTX) | 159,736 | 112,236 | -47,500 | 3,964 | 3,535 | 0.80% | -428 |
| DEXCOM INC(DXCM) | 88,279 | 86,279 | -2,000 | 5,859 | 5,418 | 1.23% | -441 |
| ACCURAY INC | 1,395,508 | 1,680,508 | +285,000 | 1,151 | 652 | 0.15% | -499 |
| IMMATICS NV(IMTX) | 261,138 | 225,860 | -35,278 | 2,742 | 2,222 | 0.51% | -519 |
| KURA ONCOLOGY INC(KURA) | 235,868 | 235,868 | 0 | 2,451 | 1,918 | 0.44% | -533 |
| PROFOUND MEDICAL CORP(PROF) | 285,710 | 263,005 | -22,705 | 2,249 | 1,704 | 0.39% | -544 |
| MEDIWOUND LTD(MDWD) | 113,612 | 94,405 | -19,207 | 2,097 | 1,521 | 0.35% | -576 |
| PROQR THERAPEUTICS N V SHS EURO | 1,567,561 | 1,567,561 | 0 | 3,166 | 2,539 | 0.58% | -627 |
| VERRICA PHARMACEUTICALS INC(VRCA) | 173,451 | 153,712 | -19,739 | 1,441 | 813 | 0.18% | -628 |
| ARCUS BIOSCIENCES INC(RCUS) | 431,329 | 443,829 | +12,500 | 10,279 | 9,587 | 2.18% | -692 |
| ASCENDIS PHARMA A/S(ASND) | 28,177 | 23,177 | -5,000 | 6,008 | 5,301 | 1.21% | -707 |
| NEUROCRINE BIOSCIENCES INC(NBIX) | 70,615 | 70,615 | 0 | 10,015 | 9,303 | 2.12% | -713 |
| ANNEXON INC(ANNX) | 272,812 | 117,812 | -155,000 | 1,370 | 653 | 0.15% | -717 |
| SYNDAX PHARMACEUTICALS INC(SNDX) | 277,855 | 217,355 | -60,500 | 5,838 | 5,077 | 1.16% | -760 |
| PROCEPT BIOROBOTICS CORP(PRCT) | 120,000 | 120,000 | 0 | 3,775 | 3,001 | 0.68% | -774 |
| TELA BIO INC(TELA) | 1,441,029 | 1,441,029 | 0 | 1,700 | 893 | 0.20% | -807 |
| AQUESTIVE THERAPEUTICS INC | 375,915 | 368,415 | -7,500 | 2,428 | 1,529 | 0.35% | -899 |
| ERASCA INC(ERAS) | 254,436 | 0 | -254,436 | 947 | 0 | — | -947 |
| TANDEM DIABETES CARE INC(TNDM) | 355,208 | 355,208 | 0 | 7,807 | 6,809 | 1.55% | -998 |
| ISHARES NASDAQ BIOTECH INDX | 68,095 | 62,095 | -6,000 | 11,492 | 10,485 | 2.39% | -1,008 |
| ARS PHARMACEUTICALS INC(SPRY) | 190,065 | 139,285 | -50,780 | 2,214 | 1,118 | 0.25% | -1,096 |
| LEXEO THERAPEUTICS INC(LXEO) | 340,859 | 377,059 | +36,200 | 3,385 | 2,164 | 0.49% | -1,220 |
| CYBIN INC(HELP) | 455,018 | 498,361 | +43,343 | 3,722 | 2,392 | 0.54% | -1,330 |
| IDEAYA BIOSCIENCES INC(IDYA) | 506,740 | 476,740 | -30,000 | 17,518 | 15,885 | 3.61% | -1,633 |
| BIOHAVEN LTD(BHVN) | 955,235 | 845,735 | -109,500 | 10,785 | 7,155 | 1.63% | -3,630 |
| ASTRIA THERAPEUTICS INC | 304,775 | 0 | -304,775 | 3,990 | 0 | — | -3,990 |
| STEREOTAXIS INC(STXS) | 13,680,554 | 13,680,554 | 0 | 31,465 | 25,172 | 5.73% | -6,293 |
| ATRICURE INC(ATRC) | 597,431 | 597,431 | 0 | 23,634 | 17,045 | 3.88% | -6,590 |
| AXOGEN INC(AXGN) | 476,826 | 249,960 | -226,866 | 15,607 | 8,281 | 1.88% | -7,325 |
| CYTOKINETICS INC(CYTK) | 370,997 | 217,497 | -153,500 | 23,573 | 14,335 | 3.26% | -9,238 |