Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q1 2026 ▲▼ | Q2 2026 ▲▼ | Change ▲▼ | Q1 2026 ▲▼ | Q2 2026 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| REVOLUTION MEDICINES INC(RVMD) | 580,678 | 562,630 | -18,048 | 56,471 | 105,369 | 20.09% | +48,898 |
| COMPASS PATHWAYS PLC(CMPS) | 2,418,882 | 2,011,952 | -406,930 | 13,376 | 28,469 | 5.43% | +15,093 |
| ASCENDIS PHARMA A/S(ASND) | 0 | 48,469 | +48,469 | 0 | 12,928 | 2.47% | +12,928 |
| DENALI THERAPEUTICS INC(DNLI) | 318,500 | 739,014 | +420,514 | 6,115 | 19,007 | 3.62% | +12,892 |
| NEKTAR THERAPEUTICS(NKTR) | 165,178 | 318,380 | +153,202 | 11,885 | 22,226 | 4.24% | +10,342 |
| INSULET CORP(PODD) | 10,870 | 61,870 | +51,000 | 2,281 | 9,420 | 1.80% | +7,139 |
| EDGEWISE THERAPEUTICS INC(EWTX) | 112,236 | 226,819 | +114,583 | 3,535 | 9,216 | 1.76% | +5,680 |
| ARCUS BIOSCIENCES INC(RCUS) | 443,829 | 441,829 | -2,000 | 9,587 | 13,622 | 2.60% | +4,035 |
| KYMERA THERAPEUTICS INC(KYMR) | 0 | 27,000 | +27,000 | 0 | 3,096 | 0.59% | +3,096 |
| ADLAI NORTYE LTD(ANL) | 0 | 239,553 | +239,553 | 0 | 2,755 | 0.53% | +2,755 |
| MAPLIGHT THERAPEUTICS INC(MPLT) | 171,006 | 171,006 | 0 | 3,477 | 6,129 | 1.17% | +2,652 |
| IDEAYA BIOSCIENCES INC(IDYA) | 476,740 | 497,240 | +20,500 | 15,885 | 18,532 | 3.53% | +2,647 |
| SYNDAX PHARMACEUTICALS INC(SNDX) | 217,355 | 335,255 | +117,900 | 5,077 | 7,329 | 1.40% | +2,251 |
| NERVGEN PHARMA CORP(NGEN) | 0 | 1,050,000 | +1,050,000 | 0 | 2,163 | 0.41% | +2,163 |
| ORTHOPEDIATRICS CORP(KIDS) | 95,659 | 189,130 | +93,471 | 1,518 | 3,618 | 0.69% | +2,100 |
| IMMUNOVANT INC(IMVT) | 150,524 | 149,524 | -1,000 | 3,739 | 5,761 | 1.10% | +2,022 |
| ATRIUM THERAPEUTICS INC(RNA) | 0 | 128,000 | +128,000 | 0 | 1,722 | 0.33% | +1,722 |
| NEUROGENE INC(NGNE) | 56,635 | 89,032 | +32,397 | 1,142 | 2,800 | 0.53% | +1,658 |
| EUPRAXIA PHARMACEUTICALS INC(EPRX) | 0 | 225,600 | +225,600 | 0 | 1,491 | 0.28% | +1,491 |
| DESIGN THERAPEUTICS INC(DSGN) | 0 | 102,600 | +102,600 | 0 | 1,485 | 0.28% | +1,485 |
| AXOGEN INC(AXGN) | 249,960 | 208,960 | -41,000 | 8,281 | 9,652 | 1.84% | +1,371 |
| AQUESTIVE THERAPEUTICS INC | 368,415 | 645,915 | +277,500 | 1,529 | 2,687 | 0.51% | +1,158 |
| ANNEXON INC(ANNX) | 117,812 | 297,812 | +180,000 | 653 | 1,701 | 0.32% | +1,048 |
| CORBUS PHARMACEUTICALS HLDGS(CRBP) | 0 | 107,773 | +107,773 | 0 | 1,011 | 0.19% | +1,011 |
| CYBIN INC(HELP) | 498,361 | 514,061 | +15,700 | 2,392 | 3,398 | 0.65% | +1,006 |
| MAZE THERAPEUTICS INC(MAZE) | 35,000 | 65,000 | +30,000 | 1,045 | 1,940 | 0.37% | +895 |
| ALLOGENE THERAPEUTICS INC | 1,370,118 | 2,000,000 | +629,882 | 3,343 | 4,160 | 0.79% | +817 |
| RAPPORT THERAPEUTICS INC(RAPP) | 75,000 | 75,000 | 0 | 2,347 | 3,125 | 0.60% | +779 |
| FATE THERAPEUTICS INC(FATE) | 550,000 | 525,000 | -25,000 | 660 | 1,418 | 0.27% | +758 |
| SEAPORT THERAPEUTICS INC | 0 | 32,400 | +32,400 | 0 | 704 | 0.13% | +704 |
| ARTIVA BIOTHERAPEUTICS INC(ARTV) | 0 | 67,101 | +67,101 | 0 | 651 | 0.12% | +651 |
| CYTOMX THERAPEUTICS INC(CTMX) | 230,000 | 438,407 | +208,407 | 1,081 | 1,644 | 0.31% | +563 |
| XENON PHARMACEUTICALS INC(XENE) | 250,772 | 250,772 | 0 | 14,582 | 15,137 | 2.89% | +554 |
| SCYNEXIS INC | 0 | 135,868 | +135,868 | 0 | 553 | 0.11% | +553 |
| EDITAS MEDICINE INC(EDIT) | 0 | 170,470 | +170,470 | 0 | 552 | 0.11% | +552 |
| NEUROCRINE BIOSCIENCES INC(NBIX) | 70,615 | 57,769 | -12,846 | 9,303 | 9,736 | 1.86% | +433 |
| Q32 BIO INC(FIXX) | 0 | 32,896 | +32,896 | 0 | 419 | 0.08% | +419 |
| DEXCOM INC(DXCM) | 86,279 | 86,279 | 0 | 5,418 | 5,811 | 1.11% | +393 |
| VIKING THERAPEUTICS INC(VKTX) | 59,516 | 59,516 | 0 | 1,937 | 2,322 | 0.44% | +385 |
| CENTURY THERAPEUTICS INC(IPSC) | 2,434,353 | 2,400,458 | -33,895 | 5,502 | 5,881 | 1.12% | +379 |
| CELLDEX THERAPEUTICS INC(CLDX) | 68,518 | 68,518 | 0 | 2,173 | 2,550 | 0.49% | +376 |
| ALKERMES PLC(ALKS) | 139,482 | 101,266 | -38,216 | 4,932 | 5,306 | 1.01% | +374 |
| NUVECTIS PHARMA INC(NVCT) | 0 | 20,000 | +20,000 | 0 | 368 | 0.07% | +368 |
| CYTOKINETICS INC(CYTK) | 217,497 | 171,998 | -45,499 | 14,335 | 14,653 | 2.79% | +317 |
| PROQR THERAPEUTICS NV SHS EURO | 1,567,561 | 1,530,361 | -37,200 | 2,539 | 2,846 | 0.54% | +307 |
| ULTRAGENYX PHARMACEUTICAL INC(RARE) | 61,100 | 47,100 | -14,000 | 1,280 | 1,573 | 0.30% | +293 |
| STRUCTURE THERAPEUTICS INC | 46,500 | 46,500 | 0 | 2,241 | 2,496 | 0.48% | +254 |
| INOGEN INC(INGN) | 845,179 | 845,179 | 0 | 5,223 | 5,451 | 1.04% | +228 |
| TENAYA THERAPEUTICS INC(TNYA) | 0 | 300,000 | +300,000 | 0 | 222 | 0.04% | +222 |
| ARS PHARMACEUTICALS INC(SPRY) | 139,285 | 164,285 | +25,000 | 1,118 | 1,316 | 0.25% | +197 |
| TELA BIO INC(TELA) | 1,441,029 | 1,441,029 | 0 | 893 | 1,081 | 0.21% | +187 |
| ADICET BIO INC | 93,812 | 93,812 | 0 | 639 | 811 | 0.15% | +172 |
| MINERALYS THERAPEUTICS INC(MLYS) | 38,490 | 44,490 | +6,000 | 1,043 | 1,200 | 0.23% | +158 |
| POLYPID LTD(PYPD) | 207,900 | 207,900 | 0 | 911 | 1,056 | 0.20% | +146 |
| ENGENE THERAPEUTICS INC(ENGN) | 0 | 74,650 | +74,650 | 0 | 129 | 0.02% | +129 |
| KARDIGAN INC | 0 | 5,000 | +5,000 | 0 | 119 | 0.02% | +119 |
| BICARA THERAPEUTICS INC | 421,733 | 284,955 | -136,778 | 8,388 | 8,460 | 1.61% | +72 |
| AUTOLUS THERAPEUTICS LTD(AUTL) | 179,316 | 179,316 | 0 | 247 | 287 | 0.05% | +39 |
| BIONTECH SE(BNTX) | 7,000 | 7,000 | 0 | 622 | 651 | 0.12% | +29 |
| PROFOUND MEDICAL CORP(PROF) | 263,005 | 260,360 | -2,645 | 1,704 | 1,731 | 0.33% | +27 |
| STOKE THERAPEUTICS INC(STOK) | 130,875 | 130,875 | 0 | 4,261 | 4,282 | 0.82% | +21 |
| FOGHORN THERAPEUTICS INC(FHTX) | 111,859 | 111,859 | 0 | 535 | 546 | 0.10% | +11 |
| ORCHESTRA BIOMED HOLDINGS INC(OBIO) | 126,841 | 126,841 | 0 | 539 | 547 | 0.10% | +8 |
| LAKEFRONT BIOTHERAPEUTICS NV(LKFT) | 130,175 | 130,175 | 0 | 3,905 | 3,903 | 0.74% | -3 |
| BICYCLE THERAPEUTICS PLC | 64,492 | 64,492 | 0 | 299 | 273 | 0.05% | -26 |
| PLIANT THERAPEUTICS INC(PLRX) | 487,000 | 487,000 | 0 | 614 | 555 | 0.11% | -58 |
| IBIO INC(IBIO) | 193,638 | 170,053 | -23,585 | 368 | 298 | 0.06% | -70 |
| BIOCRYST PHARMACEUTICALS INC(BCRX) | 430,248 | 400,248 | -30,000 | 4,096 | 4,002 | 0.76% | -93 |
| INSPIRE MEDICAL SYSTEMS INC(INSP) | 18,200 | 18,200 | 0 | 939 | 812 | 0.15% | -127 |
| ALECTOR INC | 908,351 | 908,351 | 0 | 1,953 | 1,826 | 0.35% | -127 |
| MEDIWOUND LTD(MDWD) | 94,405 | 94,405 | 0 | 1,521 | 1,388 | 0.26% | -133 |
| NEUMORA THERAPEUTICS INC(NMRA) | 70,000 | 0 | -70,000 | 137 | 0 | — | -136 |
| ADC THERAPEUTICS SA(ADCT) | 72,081 | 77,081 | +5,000 | 270 | 82 | 0.02% | -188 |
| COMPUGEN LTD(CGEN) | 257,783 | 168,232 | -89,551 | 549 | 360 | 0.07% | -189 |
| ALIGN TECHNOLOGY INC | 15,000 | 14,000 | -1,000 | 2,571 | 2,361 | 0.45% | -210 |
| ACCURAY INC | 1,680,508 | 1,680,508 | 0 | 652 | 433 | 0.08% | -219 |
| KARYOPHARM THERAPEUTICS INC(KPTI) | 45,800 | 0 | -45,800 | 255 | 0 | — | -255 |
| PROCEPT BIOROBOTICS CORP(PRCT) | 120,000 | 120,000 | 0 | 3,001 | 2,710 | 0.52% | -292 |
| ATRICURE INC(ATRC) | 597,431 | 597,431 | 0 | 17,045 | 16,716 | 3.19% | -329 |
| LEXEO THERAPEUTICS INC(LXEO) | 377,059 | 377,059 | 0 | 2,164 | 1,755 | 0.33% | -409 |
| KURA ONCOLOGY INC(KURA) | 235,868 | 120,568 | -115,300 | 1,918 | 1,323 | 0.25% | -595 |
| NEWAMSTERDAM PHARMA CO ORDINARY SHARES | 20,000 | 0 | -20,000 | 640 | 0 | — | -640 |
| VERRICA PHARMACEUTICALS INC(VRCA) | 153,712 | 23,750 | -129,962 | 813 | 145 | 0.03% | -668 |
| ZENAS BIOPHARMA INC(ZBIO) | 42,500 | 0 | -42,500 | 831 | 0 | — | -831 |
| ORIC PHARMACEUTICALS INC(ORIC) | 98,724 | 0 | -98,724 | 945 | 0 | — | -945 |
| SCYNEXIS INC(SCYX) | 1,086,956 | 0 | -1,086,956 | 997 | 0 | — | -997 |
| IMMATICS NV(IMTX) | 225,860 | 116,960 | -108,900 | 2,222 | 1,185 | 0.23% | -1,038 |
| ENGENE HOLDINGS INC COM | 187,353 | 0 | -187,353 | 1,276 | 0 | — | -1,276 |
| TANDEM DIABETES CARE INC(TNDM) | 355,208 | 355,208 | 0 | 6,809 | 5,360 | 1.02% | -1,449 |
| FULCRUM THERAPEUTICS INC(FULC) | 205,000 | 0 | -205,000 | 1,572 | 0 | — | -1,572 |
| STEREOTAXIS INC(STXS) | 13,680,554 | 13,680,554 | 0 | 25,172 | 23,531 | 4.49% | -1,642 |
| ISHARES NASDAQ BIOTECH INDX | 62,095 | 42,595 | -19,500 | 10,485 | 8,101 | 1.54% | -2,384 |
| LARIMAR THERAPEUTICS INC(LRMR) | 2,029,164 | 2,008,164 | -21,000 | 9,131 | 6,125 | 1.17% | -3,006 |
| MBX BIOSCIENCES INC(MBX) | 175,465 | 11,809 | -163,656 | 5,238 | 652 | 0.12% | -4,586 |
| BIOHAVEN LTD(BHVN) | 845,735 | 137,593 | -708,142 | 7,155 | 2,047 | 0.39% | -5,108 |
| ASCENDIS PHARMA A/S(ASND) | 23,177 | 0 | -23,177 | 5,301 | 0 | — | -5,301 |
| KALVISTA PHARMACEUTICALS INC | 267,402 | 0 | -267,402 | 5,383 | 0 | — | -5,383 |
| ASCENDIS PHARMA A/S(ASND) | 0 | 0 | 0 | 5,917 | 0 | — | -5,916 |
| SPDR S&P BIOTECH ETF ST STR SP BIOT | 318,505 | 196,505 | -122,000 | 40,683 | 31,097 | 5.93% | -9,586 |
| DAY ONE BIOPHARMACEUTICALS I COM | 978,463 | 0 | -978,463 | 20,978 | 0 | — | -20,978 |