Fund Holdings — DAFNA Capital Management LLC

Total Portfolio Value:
$524.36M
Total Bought:
$81.11M
Total Sold:
$140.23M
Net Transaction:
-$59.12M
Notable People:
Nathan Fischel, Fariba Fischel Ghodsian, Dafna Holdings, L.P.
Securities
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SharesValue
Q1 2026
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Q2 2026
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Change
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Q1 2026
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Q2 2026
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Weight (%)
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Change
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Revolution Medicines, Inc.(RVMD)580,678562,630-18,048$56.47M$105.37M20.09%+$48.90M
Spdr S&p Biotech EtfETF
ST STR SP BIOT
318,505196,505-122,000$40.68M$31.10M5.93%-$9.59M
COMPASS Pathways plcADS(CMPS)2,418,8822,011,952-406,930$13.38M$28.47M5.43%+$15.09M
Stereotaxis, Inc.(STXS)13,680,55413,680,5540$25.17M$23.53M4.49%-$1.64M
Nektar Therapeutics(NKTR)165,178318,380+153,202$11.88M$22.23M4.24%+$10.34M
Denali Therapeutics Inc.(DNLI)318,500739,014+420,514$6.12M$19.01M3.62%+$12.89M
IDEAYA Biosciences, Inc.(IDYA)476,740497,240+20,500$15.88M$18.53M3.53%+$2.65M
AtriCure, Inc.(ATRC)597,431597,4310$17.04M$16.72M3.19%-$328.6K
Xenon Pharmaceuticals Inc.(XENE)250,772250,7720$14.58M$15.14M2.89%+$554.2K
Cytokinetics, Incorporated(CYTK)217,497171,998-45,499$14.34M$14.65M2.79%+$317.3K
Arcus Biosciences, Inc.(RCUS)443,829441,829-2,000$9.59M$13.62M2.60%+$4.03M
Ascendis Pharma A/S(ASND)048,469+48,469$0$12.93M2.47%+$12.93M
Neurocrine Biosciences, Inc.(NBIX)70,61557,769-12,846$9.30M$9.74M1.86%+$433.3K
Axogen, Inc.(AXGN)249,960208,960-41,000$8.28M$9.65M1.84%+$1.37M
Insulet Corporation(PODD)10,87061,870+51,000$2.28M$9.42M1.80%+$7.14M
Edgewise Therapeutics, Inc.(EWTX)112,236226,819+114,583$3.54M$9.22M1.76%+$5.68M
Bicara Therapeutics Inc421,733284,955-136,778$8.39M$8.46M1.61%+$72.0K
Ishares Nasdaq Biotech IndxETF62,09542,595-19,500$10.48M$8.10M1.54%-$2.38M
Syndax Pharmaceuticals, Inc.(SNDX)217,355335,255+117,900$5.08M$7.33M1.40%+$2.25M
MapLight Therapeutics, Inc.(MPLT)171,006171,0060$3.48M$6.13M1.17%+$2.65M
Larimar Therapeutics, Inc.(LRMR)2,029,1642,008,164-21,000$9.13M$6.12M1.17%-$3.01M
Century Therapeutics, Inc.(IPSC)2,434,3532,400,458-33,895$5.50M$5.88M1.12%+$379.5K
DexCom, Inc.(DXCM)86,27986,2790$5.42M$5.81M1.11%+$392.6K
Immunovant, Inc.(IMVT)150,524149,524-1,000$3.74M$5.76M1.10%+$2.02M
Inogen, Inc.(INGN)845,179845,1790$5.22M$5.45M1.04%+$228.2K
Tandem Diabetes Care, Inc.(TNDM)355,208355,2080$6.81M$5.36M1.02%-$1.45M
Alkermes plcSHS(ALKS)139,482101,266-38,216$4.93M$5.31M1.01%+$373.7K
Stoke Therapeutics, Inc.(STOK)130,875130,8750$4.26M$4.28M0.82%+$20.9K
Allogene Therapeutics Inc1,370,1182,000,000+629,882$3.34M$4.16M0.79%+$816.9K
BioCryst Pharmaceuticals, Inc.(BCRX)430,248400,248-30,000$4.10M$4.00M0.76%-$93.5K
Lakefront Biotherapeutics NVADR(LKFT)130,175130,1750$3.91M$3.90M0.74%-$2.6K
OrthoPediatrics Corp.(KIDS)95,659189,130+93,471$1.52M$3.62M0.69%+$2.10M
Cybin D/B/A Helus Pharma(HELP)498,361514,061+15,700$2.39M$3.40M0.65%+$1.01M
Rapport Therapeutics, Inc.(RAPP)75,00075,0000$2.35M$3.13M0.60%+$778.5K
Kymera Therapeutics, Inc.(KYMR)027,000+27,000$0$3.10M0.59%+$3.10M
Proqr Therapeutics NvSHS EURO
SHS EURO
1,567,5611,530,361-37,200$2.54M$2.85M0.54%+$307.0K
Neurogene Inc.(NGNE)56,63589,032+32,397$1.14M$2.80M0.53%+$1.66M
Adlai Nortye Group Ltd.ADS(ANL)0239,553+239,553$0$2.75M0.53%+$2.75M
PROCEPT BioRobotics Corporation(PRCT)120,000120,0000$3.00M$2.71M0.52%-$291.6K
Aquestive Therapeutics Inc368,415645,915+277,500$1.53M$2.69M0.51%+$1.16M
Celldex Therapeutics, Inc.(CLDX)68,51868,5180$2.17M$2.55M0.49%+$376.2K
Structure Therapeutics IncADS46,50046,5000$2.24M$2.50M0.48%+$254.4K
Align Technology Inc15,00014,000-1,000$2.57M$2.36M0.45%-$210.2K
Viking Therapeutics, Inc.(VKTX)59,51659,5160$1.94M$2.32M0.44%+$385.1K
NervGen Pharma Corp.(NGEN)01,050,000+1,050,000$0$2.16M0.41%+$2.16M
Biohaven Ltd.(BHVN)845,735137,593-708,142$7.15M$2.05M0.39%-$5.11M
Maze Therapeutics, Inc.(MAZE)35,00065,000+30,000$1.04M$1.94M0.37%+$894.9K
Alector Inc908,351908,3510$1.95M$1.83M0.35%-$127.2K
Lexeo Therapeutics, Inc.(LXEO)377,059377,0590$2.16M$1.76M0.33%-$409.1K
Profound Medical Corp.(PROF)263,005260,360-2,645$1.70M$1.73M0.33%+$27.1K
Atrium Therapeutics, Inc.(RNA)0128,000+128,000$0$1.72M0.33%+$1.72M
Annexon, Inc.(ANNX)117,812297,812+180,000$652.7K$1.70M0.32%+$1.05M
CytomX Therapeutics, Inc.(CTMX)230,000438,407+208,407$1.08M$1.64M0.31%+$563.0K
Ultragenyx Pharmaceutical Inc.(RARE)61,10047,100-14,000$1.28M$1.57M0.30%+$292.6K
Eupraxia Pharmaceuticals Inc.(EPRX)0225,600+225,600$0$1.49M0.28%+$1.49M
Design Therapeutics, Inc.(DSGN)0102,600+102,600$0$1.48M0.28%+$1.48M
Fate Therapeutics, Inc.(FATE)550,000525,000-25,000$660.0K$1.42M0.27%+$757.5K
MediWound Ltd.SHS NEW(MDWD)94,40594,4050$1.52M$1.39M0.26%-$133.1K
Kura Oncology, Inc.(KURA)235,868120,568-115,300$1.92M$1.32M0.25%-$595.0K
ARS Pharmaceuticals, Inc.(SPRY)139,285164,285+25,000$1.12M$1.32M0.25%+$197.5K
Mineralys Therapeutics, Inc.(MLYS)38,49044,490+6,000$1.04M$1.20M0.23%+$157.6K
Immatics N.V.SHS(IMTX)225,860116,960-108,900$2.22M$1.18M0.23%-$1.04M
TELA Bio, Inc.(TELA)1,441,0291,441,0290$893.4K$1.08M0.21%+$187.3K
PolyPid Ltd.(PYPD)207,900207,9000$910.6K$1.06M0.20%+$145.5K
Corbus Pharmaceuticals Holdings, Inc.(CRBP)0107,773+107,773$0$1.01M0.19%+$1.01M
Inspire Medical Systems, Inc.(INSP)18,20018,2000$938.8K$811.9K0.15%-$126.9K
Adicet Bio Inc93,81293,8120$638.9K$810.5K0.15%+$171.7K
Seaport Therapeutics Inc032,400+32,400$0$703.7K0.13%+$703.7K
MBX Biosciences, Inc.(MBX)175,46511,809-163,656$5.24M$651.9K0.12%-$4.59M
BioNTech SEADS(BNTX)7,0007,0000$622.2K$651.4K0.12%+$29.2K
Artiva Biotherapeutics, Inc.(ARTV)067,101+67,101$0$650.9K0.12%+$650.9K
Pliant Therapeutics, Inc.(PLRX)487,000487,0000$613.6K$555.2K0.11%-$58.4K
Scynexis Inc0135,868+135,868$0$553.0K0.11%+$553.0K
Editas Medicine, Inc.(EDIT)0170,470+170,470$0$552.3K0.11%+$552.3K
Orchestra BioMed Holdings, Inc.(OBIO)126,841126,8410$539.1K$547.3K0.10%+$8.2K
Foghorn Therapeutics Inc.(FHTX)111,859111,8590$534.7K$545.9K0.10%+$11.2K
Accuray Inc1,680,5081,680,5080$652.2K$433.2K0.08%-$219.0K
Q32 Bio Inc.(QTTB)032,896+32,896$0$419.1K0.08%+$419.1K
Nuvectis Pharma, Inc.(NVCT)020,000+20,000$0$367.8K0.07%+$367.8K
Compugen Ltd.(CGEN)257,783168,232-89,551$549.1K$360.0K0.07%-$189.1K
iBio, Inc.(IBIO)193,638170,053-23,585$367.9K$297.6K0.06%-$70.3K
Autolus Therapeutics plcADS(AUTL)179,316179,3160$247.5K$286.9K0.05%+$39.5K
Bicycle Therapeutics PlcADS64,49264,4920$299.2K$273.4K0.05%-$25.8K
Tenaya Therapeutics, Inc.(TNYA)0300,000+300,000$0$221.7K0.04%+$221.7K
Verrica Pharmaceuticals Inc.(VRCA)153,71223,750-129,962$813.1K$145.3K0.03%-$667.8K
enGene Therapeutics Inc.(ENGN)074,650+74,650$0$129.1K0.02%+$129.1K
Kardigan Inc05,000+5,000$0$119.3K0.02%+$119.3K
ADC Therapeutics SASHS(ADCT)72,08177,081+5,000$270.3K$82.5K0.02%-$187.8K
Ascendis Pharma A/SNOTE 2 250 4 0(ASND)000$5.92M$0—-$5.92M
Ascendis Pharma A/SADR(ASND)23,1770-23,177$5.30M$0—-$5.30M
Day One Biopharmaceuticals I
COM
978,4630-978,463$20.98M$0—-$20.98M
Engene Holdings Inc
COM
187,3530-187,353$1.28M$0—-$1.28M
Fulcrum Therapeutics, Inc.(FULC)205,0000-205,000$1.57M$0—-$1.57M
Kalvista Pharmaceuticals Inc267,4020-267,402$5.38M$0—-$5.38M
Karyopharm Therapeutics Inc.(KPTI)45,8000-45,800$255.1K$0—-$255.1K
Neumora Therapeutics, Inc.(NMRA)70,0000-70,000$136.5K$0—-$136.5K
Newamsterdam Pharma Co
ORDINARY SHARES
20,0000-20,000$640.2K$0—-$640.2K
ORIC Pharmaceuticals, Inc.(ORIC)98,7240-98,724$945.5K$0—-$945.5K
SCYNEXIS, Inc.(SCYX)1,086,9560-1,086,956$996.6K$0—-$996.6K
Zenas BioPharma, Inc.(ZBIO)42,5000-42,500$830.9K$0—-$830.9K
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DAFNA Capital Management LLC — 13F Holdings — Q2 2026 | TickerTrail