Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q1 2026 ▲▼ | Q2 2026 ▲▼ | Change ▲▼ | Q1 2026 ▲▼ | Q2 2026 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| AZITRA INC | 0 | 81,797,553 | +81,797,553 | 0 | 7,981 | 3.74% | +7,981 |
| AYTU BIOPHARMA INC | 792,289 | 4,990,238 | +4,197,949 | 2,163 | 9,624 | 4.51% | +7,461 |
| CNS PHARMACEUTICALS INC | 61,000 | 1,345,921 | +1,284,921 | 146 | 6,434 | 3.01% | +6,288 |
| ELOXX PHARMACEUTICALS INC | 0 | 447,160 | +447,160 | 0 | 6,207 | 2.91% | +6,207 |
| CAMP4 THERAPEUTICS CORP | 0 | 1,389,622 | +1,389,622 | 0 | 6,073 | 2.84% | +6,073 |
| INSMED INC(INSM)(Call) | 0 | 40,000 | +40,000 | 0 | 5,600 | — | +5,600 |
| ULTRAGENYX PHARMACEUTICAL IN(RARE)(Call) | 0 | 200,000 | +200,000 | 0 | 5,500 | — | +5,500 |
| MEDTRONIC PLC(MDT)(Call) | 0 | 50,000 | +50,000 | 0 | 4,375 | — | +4,375 |
| INDIVIOR PHARMACEUTICALS INC(INDV) | 0 | 100,000 | +100,000 | 0 | 4,103 | 1.92% | +4,103 |
| EVOLUS INC | 0 | 1,590,162 | +1,590,162 | 0 | 11,036 | 5.17% | +11,036 |
| ABBOTT LABORATORIES(Call) | 0 | 40,000 | +40,000 | 0 | 3,800 | — | +3,800 |
| SURROZEN INC | 33,005 | 68,001 | +34,996 | 961 | 4,710 | 2.20% | +3,748 |
| BOSTON SCIENTIFIC CORP(BSX)(Call) | 0 | 50,000 | +50,000 | 0 | 3,250 | — | +3,250 |
| SATELLOS BIOSCIENCE INC | 100,000 | 491,624 | +391,624 | 563 | 3,723 | 1.74% | +3,160 |
| BIOMARIN PHARMACEUTICAL INC(BMRN)(Call) | 0 | 50,000 | +50,000 | 0 | 3,125 | — | +3,125 |
| EDESA BIOTECH INC(EDSA) | 30,000 | 456,439 | +426,439 | 157 | 3,191 | 1.49% | +3,034 |
| CABALETTA BIO INC | 50,000 | 917,100 | +867,100 | 135 | 2,852 | 1.34% | +2,718 |
| NEKTAR THERAPEUTICS(NKTR) | 85,000 | 120,654 | +35,654 | 6,116 | 8,423 | 3.94% | +2,307 |
| KAZIA THERAPEUTICS LTD | 345,179 | 345,179 | 0 | 2,568 | 4,860 | 2.28% | +2,292 |
| XILIO THERAPEUTICS INC | 0 | 225,994 | +225,994 | 0 | 2,165 | 1.01% | +2,165 |
| QUOIN PHARMACEUTICALS LTD | 53,460 | 765,546 | +712,086 | 353 | 2,042 | 0.96% | +1,689 |
| ADIAL PHARMACEUTICALS INC | 0 | 727,563 | +727,563 | 0 | 1,583 | 0.74% | +1,583 |
| SPRUCE BIOSCIENCES INC | 0 | 28,795 | +28,795 | 0 | 1,555 | 0.73% | +1,555 |
| EVOLUS INC(Call) | 420,000 | 420,000 | 0 | 1,726 | 3,150 | — | +1,424 |
| IN8BIO INC | 663,412 | 1,624,562 | +961,150 | 982 | 2,291 | 1.07% | +1,309 |
| CALCIMEDICA INC | 0 | 2,128,597 | +2,128,597 | 0 | 1,263 | 0.59% | +1,263 |
| CURIS INC | 3,726,406 | 14,312,187 | +10,585,781 | 2,039 | 3,150 | 1.47% | +1,111 |
| MOONLAKE IMMUNOTHERAPEUTICS(MLTX) | 0 | 50,000 | +50,000 | 0 | 974 | 0.46% | +974 |
| ULTRAGENYX PHARMACEUTICAL IN(RARE) | 0 | 25,000 | +25,000 | 0 | 835 | 0.39% | +835 |
| INHIBIKASE THERAPEUTICS INC | 957,202 | 2,468,595 | +1,511,393 | 1,608 | 2,379 | 1.11% | +771 |
| NERVGEN PHARMA CORP | 0 | 571,678 | +571,678 | 0 | 740 | 0.35% | +740 |
| NUVECTIS PHARMA INC | 0 | 40,000 | +40,000 | 0 | 736 | 0.34% | +736 |
| ORUKA THERAPEUTICS INC(ORKA) | 0 | 7,500 | +7,500 | 0 | 714 | 0.33% | +714 |
| HERON THERAPEUTICS INC(Call) | 1,000,000 | 1,000,000 | 0 | 800 | 1,500 | — | +700 |
| ADICET BIO INC | 221,955 | 245,518 | +23,563 | 1,512 | 2,121 | 0.99% | +610 |
| SINTX TECHNOLOGIES INC | 0 | 627,615 | +627,615 | 0 | 558 | 0.26% | +558 |
| IMAGENEBIO INC | 0 | 96,172 | +96,172 | 0 | 539 | 0.25% | +539 |
| PASITHEA THERAPEUTICS CORP | 831,301 | 2,201,468 | +1,370,167 | 617 | 1,135 | 0.53% | +518 |
| XERIS BIOPHARMA HOLDINGS INC(Call) | 280,000 | 280,000 | 0 | 1,624 | 2,100 | — | +476 |
| QT IMAGING HLDGS INC | 0 | 100,000 | +100,000 | 0 | 407 | 0.19% | +407 |
| CORBUS PHARMACEUTICALS HLDGS | 383,462 | 425,000 | +41,538 | 3,601 | 3,987 | 1.87% | +386 |
| TELA BIO INC | 2,617,252 | 2,662,427 | +45,175 | 1,623 | 1,997 | 0.93% | +374 |
| PHATHOM PHARMACEUTICALS INC | 50,010 | 85,010 | +35,000 | 556 | 922 | 0.43% | +367 |
| MILESTONE PHARMACEUTICALS IN | 0 | 666,666 | +666,666 | 0 | 349 | 0.16% | +349 |
| CYBIN INC | 134,060 | 330,530 | +196,470 | 643 | 966 | 0.45% | +322 |
| CELLECTAR BIOSCIENCES INC | 0 | 104,550 | +104,550 | 0 | 291 | 0.14% | +291 |
| EUPRAXIA PHARMACEUTICALS INC | 0 | 43,491 | +43,491 | 0 | 287 | 0.13% | +287 |
| ADLAI NORTYE LTD(ANL) | 0 | 24,257 | +24,257 | 0 | 279 | 0.13% | +279 |
| SENSEONICS HLDGS INC | 0 | 48,680 | +48,680 | 0 | 277 | 0.13% | +277 |
| NEUMORA THERAPEUTICS INC.(Call) | 500,000 | 500,000 | 0 | 975 | 1,250 | — | +275 |
| SI BONE INC(SIBN)(Call) | 100,000 | 100,000 | 0 | 1,263 | 1,500 | — | +237 |
| AN2 THERAPEUTICS INC | 713,845 | 551,692 | -162,153 | 2,441 | 2,670 | 1.25% | +229 |
| REIN THERAPEUTICS INC | 0 | 218,038 | +218,038 | 0 | 227 | 0.11% | +227 |
| MAXCYTE INC | 1,004,673 | 751,606 | -253,067 | 706 | 924 | 0.43% | +219 |
| INOVIO PHARMACEUTICALS INC | 0 | 1,345,237 | +1,345,237 | 0 | 210 | 0.10% | +210 |
| ARVINAS INC | 27,500 | 60,000 | +32,500 | 292 | 499 | 0.23% | +207 |
| HUMACYTE INC | 0 | 231,299 | +231,299 | 0 | 181 | 0.08% | +181 |
| ZENTALIS PHARMACEUTICALS INC | 269,100 | 161,583 | -107,517 | 630 | 784 | 0.37% | +154 |
| ARDELYX INC(Call) | 150,000 | 150,000 | 0 | 899 | 1,050 | — | +152 |
| PRECISION BIOSCIENCES INC | 0 | 40,000 | +40,000 | 0 | 128 | 0.06% | +128 |
| TENAYA THERAPEUTICS INC | 0 | 352,001 | +352,001 | 0 | 107 | 0.05% | +107 |
| OPUS GENETICS INC | 68,688 | 100,718 | +32,030 | 313 | 414 | 0.19% | +101 |
| ABEONA THERAPEUTICS INC | 746,587 | 557,284 | -189,303 | 3,345 | 3,444 | 1.61% | +99 |
| SAB BIOTHERAPEUTICS INC | 50,000 | 73,271 | +23,271 | 192 | 286 | 0.13% | +94 |
| DELCATH SYS INC(Call) | 100,000 | 100,000 | 0 | 928 | 1,000 | — | +72 |
| PULMONX CORP | 768,288 | 815,436 | +47,148 | 991 | 1,060 | 0.50% | +69 |
| BIOATLA INC | 0 | 16,432 | +16,432 | 0 | 68 | 0.03% | +68 |
| GRACE THERAPEUTICS INC | 0 | 294,550 | +294,550 | 0 | 62 | 0.03% | +62 |
| RADIOPHARM THERANOSTICS LTD | 51,000,000 | 102,000,000 | +51,000,000 | 739 | 794 | 0.37% | +55 |
| CONNECT BIOPHARMA HLDGS LTD | 310,000 | 364,254 | +54,254 | 812 | 867 | 0.41% | +55 |
| ONKURE THERAPEUTICS INC | 132,578 | 130,684 | -1,894 | 549 | 596 | 0.28% | +47 |
| KALARIS THERAPEUTICS INC | 20,400 | 30,122 | +9,722 | 118 | 123 | 0.06% | +5 |
| APREA THERAPEUTICS INC | 0 | 137,174 | +137,174 | 0 | 0 | — | 0 |
| BIOATLA INC | 65,387 | 0 | -65,387 | 11 | 0 | — | -11 |
| EVAXION AS | 19,713 | 17,562 | -2,151 | 73 | 54 | 0.03% | -19 |
| PLIANT THERAPEUTICS INC | 224,650 | 230,538 | +5,888 | 283 | 263 | 0.12% | -20 |
| OVID THERAPEUTICS INC | 40,000 | 21,300 | -18,700 | 89 | 57 | 0.03% | -32 |
| PROCESSA PHARMACEUTICALS INC | 55,000 | 55,000 | 0 | 139 | 106 | 0.05% | -33 |
| MANNKIND CORP(MNKD) | 16,300 | 0 | -16,300 | 40 | 0 | — | -40 |
| OKYO PHARMA LTD | 850,000 | 862,996 | +12,996 | 1,369 | 1,294 | 0.61% | -74 |
| UPSTREAM BIO INC | 35,000 | 33,432 | -1,568 | 315 | 231 | 0.11% | -84 |
| ELEDON PHARMACEUTICALS INC | 35,000 | 0 | -35,000 | 108 | 0 | — | -108 |
| COMPUGEN LTD | 104,300 | 31,387 | -72,913 | 222 | 67 | 0.03% | -155 |
| PMV PHARMACEUTICALS INC | 708,102 | 536,086 | -172,016 | 878 | 718 | 0.34% | -160 |
| CYTOMX THERAPEUTICS INC. | 200,000 | 205,000 | +5,000 | 940 | 769 | 0.36% | -171 |
| SI BONE INC(SIBN) | 14,964 | 0 | -14,964 | 189 | 0 | — | -189 |
| NEUMORA THERAPEUTICS INC. | 100,000 | 0 | -100,000 | 195 | 0 | — | -195 |
| PRECISION OPTICS CORP INC MA | 100,000 | 46,390 | -53,610 | 439 | 237 | 0.11% | -202 |
| XERIS BIOPHARMA HOLDINGS INC | 40,030 | 0 | -40,030 | 232 | 0 | — | -232 |
| OMNIAB INC | 164,045 | 0 | -164,045 | 258 | 0 | — | -258 |
| BOUNDLESS BIO INC | 597,682 | 154,595 | -443,087 | 657 | 386 | 0.18% | -271 |
| JANUX THERAPEUTICS INC(JANX) | 20,000 | 0 | -20,000 | 278 | 0 | — | -278 |
| VERRICA PHARMACEUTICALS INC | 99,735 | 88,417 | -11,318 | 528 | 241 | 0.11% | -286 |
| X4 PHARMACEUTICALS INC | 335,309 | 224,989 | -110,320 | 1,385 | 1,051 | 0.49% | -334 |
| ESTABLISHMENT LABS HLDGS INC(ESTA) | 6,000 | 0 | -6,000 | 341 | 0 | — | -341 |
| BIOAGE LABS INC | 50,000 | 20,000 | -30,000 | 875 | 490 | 0.23% | -384 |
| CODEXIS INC | 417,994 | 109,662 | -308,332 | 681 | 248 | 0.12% | -433 |
| ABEONA THERAPEUTICS INC(Call) | 100,000 | 0 | -100,000 | 448 | 0 | — | -448 |
| ADMA BIOLOGICS INC | 0 | 740,000 | +740,000 | 0 | 6,194 | 2.90% | +6,194 |
| MANNKIND CORP(MNKD)(Call) | 500,000 | 250,000 | -250,000 | 1,225 | 750 | — | -475 |