Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q4 2024 ▲▼ | Q1 2025 ▲▼ | Change ▲▼ | Q4 2024 ▲▼ | Q1 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| ELEVANCE HEALTH INC(ELV) | 0 | 88,222 | +88,222 | 0 | 38,373 | 2.94% | +38,373 |
| SOLENO THERAPEUTICS INC | 307,503 | 595,206 | +287,703 | 13,822 | 42,527 | 3.26% | +28,705 |
| AXSOME THERAPEUTICS INC(AXSM) | 467,427 | 556,545 | +89,118 | 39,549 | 64,910 | 4.98% | +25,361 |
| ALNYLAM PHARMACEUTICALS INC(ALNY) | 0 | 87,145 | +87,145 | 0 | 23,531 | 1.80% | +23,531 |
| BRIDGEBIO PHARMA INC(BBIO) | 290,242 | 908,135 | +617,893 | 7,964 | 31,394 | 2.41% | +23,430 |
| ASCENDIS PHARMA A/S(ASND) | 52,392 | 186,916 | +134,524 | 7,213 | 29,133 | 2.23% | +21,920 |
| CVS HEALTH CORP(CVS) | 0 | 312,305 | +312,305 | 0 | 21,159 | 1.62% | +21,159 |
| BECTON DICKINSON & CO(BDX) | 0 | 91,571 | +91,571 | 0 | 20,975 | 1.61% | +20,975 |
| OUTSET MED INC(OM) | 0 | 1,685,727 | +1,685,727 | 0 | 18,644 | 1.43% | +18,644 |
| INDIVIOR PLC | 0 | 1,159,833 | +1,159,833 | 0 | 11,053 | 0.85% | +11,053 |
| ASTRAZENECA PLC(AZN) | 0 | 150,200 | +150,200 | 0 | 11,040 | 0.85% | +11,040 |
| ABBVIE INC(ABBV) | 331,741 | 331,741 | 0 | 58,950 | 69,506 | 5.33% | +10,556 |
| VERTEX PHARMACEUTICALS INC(VRTX) | 126,989 | 126,989 | 0 | 51,138 | 61,567 | 4.72% | +10,428 |
| MCKESSON CORP(MCK) | 97,498 | 97,498 | 0 | 55,565 | 65,615 | 5.03% | +10,050 |
| SYNDAX PHARMACEUTICALS INC(SNDX) | 206,871 | 926,424 | +719,553 | 2,735 | 11,381 | 0.87% | +8,646 |
| HCA HEALTHCARE INC(HCA) | 69,441 | 77,464 | +8,023 | 20,843 | 26,768 | 2.05% | +5,925 |
| NEOGENOMICS INC(NEO) | 0 | 585,381 | +585,381 | 0 | 5,555 | 0.43% | +5,555 |
| PENUMBRA INC(PEN) | 166,261 | 166,261 | 0 | 39,484 | 44,460 | 3.41% | +4,976 |
| TENET HEALTHCARE CORP(THC) | 491,334 | 491,334 | 0 | 62,021 | 66,084 | 5.07% | +4,063 |
| INHIBRX BIOSCIENCES INC(INBX) | 135,546 | 439,283 | +303,737 | 2,087 | 6,146 | 0.47% | +4,058 |
| AMYLYX PHARMACEUTICALS INC(AMLX) | 0 | 834,135 | +834,135 | 0 | 2,953 | 0.23% | +2,953 |
| MOLINA HEALTHCARE INC(MOH) | 70,088 | 70,088 | 0 | 20,399 | 23,086 | 1.77% | +2,687 |
| SPDR SER TR ST STR SP RETAIL | 0 | 36,471 | +36,471 | 0 | 2,520 | 0.19% | +2,520 |
| ASCENDIS PHARMA A/S(ASND) | 0 | 0 | 0 | 25,329 | 27,345 | 2.10% | +2,016 |
| CENTESSA PHARMACEUTICALS PLC | 371,766 | 570,546 | +198,780 | 6,227 | 8,204 | 0.63% | +1,977 |
| ARGENX SE(ARGX) | 63,699 | 68,999 | +5,300 | 39,175 | 40,838 | 3.13% | +1,663 |
| UNIQURE NV(QURE) | 283,158 | 599,967 | +316,809 | 5,001 | 6,360 | 0.49% | +1,359 |
| SPRINGWORKS THERAPEUTICS INC | 0 | 26,437 | +26,437 | 0 | 1,167 | 0.09% | +1,167 |
| SAREPTA THERAPEUTICS INC(SRPT) | 0 | 0 | 0 | 8,529 | 9,310 | 0.71% | +781 |
| STRUCTURE THERAPEUTICS INC | 0 | 40,400 | +40,400 | 0 | 699 | 0.05% | +699 |
| CAPRICOR THERAPEUTICS INC(CAPR) | 54,357 | 140,681 | +86,324 | 750 | 1,335 | 0.10% | +585 |
| PMV PHARMACEUTICALS INC(PMVP) | 2,079,245 | 3,301,942 | +1,222,697 | 3,140 | 3,599 | 0.28% | +459 |
| IO BIOTECH INC(IOBTQ) | 2,341,107 | 2,341,107 | 0 | 2,154 | 2,552 | 0.20% | +398 |
| BLUEPRINT MEDICINES CORP | 42,840 | 46,453 | +3,613 | 3,737 | 4,112 | 0.32% | +375 |
| VERVE THERAPEUTICS INC | 125,999 | 155,495 | +29,496 | 711 | 711 | 0.05% | -0 |
| THERMO FISHER SCIENTIFIC INC(TMO) | 21,040 | 21,897 | +857 | 10,946 | 10,896 | 0.84% | -50 |
| TURNSTONE BIOLOGICS CORP | 932,348 | 932,348 | 0 | 463 | 382 | 0.03% | -81 |
| OSCAR HEALTH INC(OSCR) | 860,821 | 860,821 | 0 | 11,569 | 11,285 | 0.87% | -284 |
| BOUNDLESS BIO INC(BOLD) | 240,513 | 240,513 | 0 | 697 | 363 | 0.03% | -334 |
| COMPASS PATHWAYS PLC(CMPS) | 451,267 | 451,267 | 0 | 1,706 | 1,291 | 0.10% | -415 |
| CENTENE CORP DEL(CNC) | 144,501 | 135,398 | -9,103 | 8,754 | 8,220 | 0.63% | -534 |
| IOVANCE BIOTHERAPEUTICS INC(IOVA) | 132,152 | 132,152 | 0 | 978 | 440 | 0.03% | -538 |
| KEROS THERAPEUTICS INC(KROS) | 104,323 | 104,323 | 0 | 1,651 | 1,063 | 0.08% | -588 |
| BLUEBIRD BIO INC | 75,758 | 0 | -75,758 | 632 | 0 | — | -632 |
| SAGIMET BIOSCIENCES INC(SGMT) | 649,006 | 649,006 | 0 | 2,921 | 2,116 | 0.16% | -805 |
| GENERATION BIO CO | 787,914 | 0 | -787,914 | 835 | 0 | — | -835 |
| XENON PHARMACEUTICALS INC(XENE) | 116,998 | 92,236 | -24,762 | 4,586 | 3,095 | 0.24% | -1,492 |
| CELCUITY INC(CELC) | 158,746 | 53,349 | -105,397 | 2,078 | 539 | 0.04% | -1,539 |
| WEREWOLF THERAPEUTICS INC(HOWL) | 2,905,465 | 2,506,520 | -398,945 | 4,300 | 2,437 | 0.19% | -1,863 |
| METAGENOMI INC(MGX) | 885,803 | 885,803 | 0 | 3,198 | 1,205 | 0.09% | -1,993 |
| JAZZ PHARMACEUTICALS PLC(JAZZ) | 17,597 | 0 | -17,597 | 2,167 | 0 | — | -2,167 |
| IQVIA HLDGS INC(IQV) | 111,854 | 111,854 | 0 | 21,980 | 19,720 | 1.51% | -2,261 |
| ALKERMES PLC(ALKS) | 80,719 | 0 | -80,719 | 2,321 | 0 | — | -2,321 |
| INTUITIVE SURGICAL INC | 93,073 | 93,073 | 0 | 48,580 | 46,096 | 3.54% | -2,484 |
| ADAPTIMMUNE THERAPEUTICS PLC(ADAPY) | 4,871,969 | 0 | -4,871,969 | 2,625 | 0 | — | -2,625 |
| WATERS CORP(WAT) | 59,053 | 51,858 | -7,195 | 21,907 | 19,113 | 1.47% | -2,794 |
| TG THERAPEUTICS INC(TGTX) | 98,674 | 0 | -98,674 | 2,970 | 0 | — | -2,970 |
| INSMED INC(INSM) | 43,774 | 0 | -43,774 | 3,022 | 0 | — | -3,022 |
| PRAXIS PRECISION MEDICINES I(PRAX) | 119,509 | 160,866 | +41,357 | 9,197 | 6,092 | 0.47% | -3,105 |
| ARCELLX INC COMMON STOCK | 56,603 | 15,488 | -41,115 | 4,341 | 1,016 | 0.08% | -3,325 |
| INTRA-CELLULAR THERAPIES INC | 40,610 | 0 | -40,610 | 3,392 | 0 | — | -3,392 |
| BIONTECH SE(BNTX) | 33,109 | 0 | -33,109 | 3,773 | 0 | — | -3,773 |
| CARIBOU BIOSCIENCES INC(CRBU) | 3,876,462 | 2,506,435 | -1,370,027 | 6,164 | 2,289 | 0.18% | -3,875 |
| HUMANA INC(HUM) | 83,037 | 63,238 | -19,799 | 21,067 | 16,733 | 1.28% | -4,335 |
| ELI LILLY & CO(LLY) | 298,643 | 273,778 | -24,865 | 230,552 | 226,116 | 17.34% | -4,436 |
| KRANESHARES TRUST | 180,974 | 0 | -180,974 | 5,292 | 0 | — | -5,292 |
| DANAHER CORPORATION(DHR) | 125,515 | 112,475 | -13,040 | 28,812 | 23,057 | 1.77% | -5,755 |
| ERASCA INC(ERAS) | 4,390,427 | 3,489,559 | -900,868 | 11,020 | 4,781 | 0.37% | -6,239 |
| SPDR S&P 500 ETF TR(SPY) | 12,427 | 0 | -12,427 | 7,283 | 0 | — | -7,283 |
| TEVA PHARMACEUTICAL INDS LTD(TEVA) | 397,024 | 0 | -397,024 | 8,750 | 0 | — | -8,750 |
| SAREPTA THERAPEUTICS INC(SRPT) | 100,172 | 50,809 | -49,363 | 12,180 | 3,243 | 0.25% | -8,937 |
| UNIVERSAL HLTH SVCS INC(UHS) | 213,983 | 155,520 | -58,463 | 38,393 | 29,222 | 2.24% | -9,171 |
| BIOHAVEN LTD(BHVN) | 431,916 | 197,307 | -234,609 | 16,132 | 4,743 | 0.36% | -11,389 |
| SELECT SECTOR SPDR TR ST STR CARE ETF | 83,806 | 0 | -83,806 | 11,529 | 0 | — | -11,529 |
| VEEVA SYS INC(VEEV) | 55,383 | 0 | -55,383 | 11,644 | 0 | — | -11,644 |
| STRYKER CORPORATION(SYK) | 32,349 | 0 | -32,349 | 11,647 | 0 | — | -11,647 |
| EDWARDS LIFESCIENCES CORP | 594,172 | 379,954 | -214,218 | 43,987 | 27,539 | 2.11% | -16,447 |
| CARDINAL HEALTH INC(CAH) | 148,173 | 0 | -148,173 | 17,524 | 0 | — | -17,524 |
| UNITED THERAPEUTICS CORP DEL(UTHR) | 52,500 | 0 | -52,500 | 18,524 | 0 | — | -18,524 |
| INVESCO EXCHANGE TRADED FD T S&P500 EQL WGT | 108,041 | 0 | -108,041 | 18,932 | 0 | — | -18,932 |
| UNITEDHEALTH GROUP INC(UNH) | 75,588 | 35,904 | -39,684 | 38,237 | 18,805 | 1.44% | -19,432 |
| ICON PLC(ICLR) | 128,637 | 41,038 | -87,599 | 26,976 | 7,181 | 0.55% | -19,795 |
| ISHARES TR | 347,637 | 0 | -347,637 | 21,661 | 0 | — | -21,661 |
| NEUROCRINE BIOSCIENCES INC(NBIX) | 166,803 | 0 | -166,803 | 22,769 | 0 | — | -22,769 |
| DEXCOM INC(DXCM) | 328,763 | 0 | -328,763 | 25,568 | 0 | — | -25,568 |