Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q3 2024 ▲▼ | Q4 2024 ▲▼ | Change ▲▼ | Q3 2024 ▲▼ | Q4 2024 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| DEXCOM INC(DXCM) | 0 | 328,763 | +328,763 | 0 | 25,568 | 1.95% | +25,568 |
| NEUROCRINE BIOSCIENCES INC(NBIX) | 0 | 166,803 | +166,803 | 0 | 22,769 | 1.73% | +22,769 |
| ISHARES TR | 0 | 347,637 | +347,637 | 0 | 21,661 | 1.65% | +21,661 |
| INVESCO EXCHANGE TRADED FD T S&P500 EQL WGT | 0 | 108,041 | +108,041 | 0 | 18,932 | 1.44% | +18,932 |
| UNITED THERAPEUTICS CORP DEL(UTHR) | 0 | 52,500 | +52,500 | 0 | 18,524 | 1.41% | +18,524 |
| EDWARDS LIFESCIENCES CORP | 390,863 | 594,172 | +203,309 | 25,793 | 43,987 | 3.35% | +18,194 |
| CARDINAL HEALTH INC(CAH) | 0 | 148,173 | +148,173 | 0 | 17,524 | 1.33% | +17,524 |
| BIOHAVEN LTD(BHVN) | 0 | 431,916 | +431,916 | 0 | 16,132 | 1.23% | +16,132 |
| SOLENO THERAPEUTICS INC | 0 | 307,503 | +307,503 | 0 | 13,822 | 1.05% | +13,822 |
| SELECT SECTOR SPDR TR ST STR CARE ETF | 0 | 83,806 | +83,806 | 0 | 11,529 | 0.88% | +11,529 |
| CENTENE CORP DEL(CNC) | 0 | 144,501 | +144,501 | 0 | 8,754 | 0.67% | +8,754 |
| TEVA PHARMACEUTICAL INDS LTD(TEVA) | 0 | 397,024 | +397,024 | 0 | 8,750 | 0.67% | +8,750 |
| BRIDGEBIO PHARMA INC(BBIO) | 0 | 290,242 | +290,242 | 0 | 7,964 | 0.61% | +7,964 |
| VEEVA SYS INC(VEEV) | 19,259 | 55,383 | +36,124 | 4,042 | 11,644 | 0.89% | +7,602 |
| MCKESSON CORP(MCK) | 97,498 | 97,498 | 0 | 48,205 | 55,565 | 4.23% | +7,360 |
| SPDR S&P 500 ETF TR(SPY) | 0 | 12,427 | +12,427 | 0 | 7,283 | 0.55% | +7,283 |
| PENUMBRA INC(PEN) | 166,261 | 166,261 | 0 | 32,306 | 39,484 | 3.01% | +7,177 |
| KRANESHARES TRUST | 0 | 180,974 | +180,974 | 0 | 5,292 | 0.40% | +5,292 |
| UNIQURE NV(QURE) | 121,628 | 283,158 | +161,530 | 600 | 5,001 | 0.38% | +4,401 |
| BIONTECH SE(BNTX) | 0 | 33,109 | +33,109 | 0 | 3,773 | 0.29% | +3,773 |
| BLUEPRINT MEDICINES CORP | 0 | 42,840 | +42,840 | 0 | 3,737 | 0.28% | +3,737 |
| WATERS CORP(WAT) | 51,063 | 59,053 | +7,990 | 18,377 | 21,907 | 1.67% | +3,530 |
| JAZZ PHARMACEUTICALS PLC(JAZZ) | 0 | 17,597 | +17,597 | 0 | 2,167 | 0.17% | +2,167 |
| CENTESSA PHARMACEUTICALS PLC | 269,158 | 371,766 | +102,608 | 4,304 | 6,227 | 0.47% | +1,923 |
| SAREPTA THERAPEUTICS INC(SRPT) | 88,216 | 100,172 | +11,956 | 11,017 | 12,180 | 0.93% | +1,163 |
| SAGIMET BIOSCIENCES INC(SGMT) | 649,006 | 649,006 | 0 | 1,798 | 2,921 | 0.22% | +1,123 |
| METAGENOMI INC(MGX) | 1,034,002 | 885,803 | -148,199 | 2,244 | 3,198 | 0.24% | +954 |
| BLUEBIRD BIO INC | 0 | 75,758 | +75,758 | 0 | 632 | 0.05% | +632 |
| PMV PHARMACEUTICALS INC(PMVP) | 2,011,040 | 2,079,245 | +68,205 | 2,996 | 3,140 | 0.24% | +143 |
| VERVE THERAPEUTICS INC | 125,999 | 125,999 | 0 | 610 | 711 | 0.05% | +101 |
| INHIBRX BIOSCIENCES INC(INBX) | 135,546 | 135,546 | 0 | 2,123 | 2,087 | 0.16% | -35 |
| TURNSTONE BIOLOGICS CORP | 932,348 | 932,348 | 0 | 519 | 463 | 0.04% | -56 |
| BOUNDLESS BIO INC(BOLD) | 240,513 | 240,513 | 0 | 835 | 697 | 0.05% | -137 |
| IOVANCE BIOTHERAPEUTICS INC(IOVA) | 132,152 | 132,152 | 0 | 1,241 | 978 | 0.07% | -263 |
| SAREPTA THERAPEUTICS INC(SRPT) | 0 | 0 | 0 | 8,804 | 8,529 | 0.65% | -275 |
| IO BIOTECH INC(IOBTQ) | 2,341,107 | 2,341,107 | 0 | 2,458 | 2,154 | 0.16% | -304 |
| ARCELLX INC COMMON STOCK | 60,602 | 56,603 | -3,999 | 5,061 | 4,341 | 0.33% | -720 |
| GENERATION BIO CO | 787,914 | 787,914 | 0 | 1,946 | 835 | 0.06% | -1,111 |
| COMPASS PATHWAYS PLC(CMPS) | 451,267 | 451,267 | 0 | 2,843 | 1,706 | 0.13% | -1,137 |
| PRAXIS PRECISION MEDICINES I(PRAX) | 183,092 | 119,509 | -63,583 | 10,535 | 9,197 | 0.70% | -1,338 |
| ASCENDIS PHARMA A/S(ASND) | 0 | 0 | 0 | 26,815 | 25,329 | 1.93% | -1,486 |
| CAPRICOR THERAPEUTICS INC(CAPR) | 152,779 | 54,357 | -98,422 | 2,324 | 750 | 0.06% | -1,574 |
| CELLDEX THERAPEUTICS INC NEW(CLDX) | 52,120 | 0 | -52,120 | 1,772 | 0 | — | -1,772 |
| ARK ETF TR GENOMIC REV ETF | 86,934 | 0 | -86,934 | 2,226 | 0 | — | -2,226 |
| INTRA-CELLULAR THERAPIES INC | 77,387 | 40,610 | -36,777 | 5,662 | 3,392 | 0.26% | -2,271 |
| CARIBOU BIOSCIENCES INC(CRBU) | 4,306,671 | 3,876,462 | -430,209 | 8,441 | 6,164 | 0.47% | -2,277 |
| ERASCA INC(ERAS) | 4,876,911 | 4,390,427 | -486,484 | 13,314 | 11,020 | 0.84% | -2,294 |
| AXSOME THERAPEUTICS INC(AXSM) | 467,427 | 467,427 | 0 | 42,008 | 39,549 | 3.01% | -2,459 |
| TG THERAPEUTICS INC(TGTX) | 233,410 | 98,674 | -134,736 | 5,459 | 2,970 | 0.23% | -2,489 |
| XENON PHARMACEUTICALS INC(XENE) | 179,878 | 116,998 | -62,880 | 7,082 | 4,586 | 0.35% | -2,495 |
| WEREWOLF THERAPEUTICS INC(HOWL) | 3,398,747 | 2,905,465 | -493,282 | 7,205 | 4,300 | 0.33% | -2,905 |
| PULMONX CORP(LUNG) | 368,929 | 0 | -368,929 | 3,058 | 0 | — | -3,058 |
| CULLINAN THERAPEUTICS INC(CGEM) | 182,810 | 0 | -182,810 | 3,060 | 0 | — | -3,060 |
| ALKERMES PLC(ALKS) | 205,073 | 80,719 | -124,354 | 5,740 | 2,321 | 0.18% | -3,419 |
| IMMUNOVANT INC(IMVT) | 122,701 | 0 | -122,701 | 3,498 | 0 | — | -3,498 |
| OCULAR THERAPEUTIX INC(OCUL) | 402,843 | 0 | -402,843 | 3,505 | 0 | — | -3,505 |
| MOLINA HEALTHCARE INC(MOH) | 70,088 | 70,088 | 0 | 24,150 | 20,399 | 1.55% | -3,750 |
| LONGBOARD PHARMACEUTICALS IN | 113,711 | 0 | -113,711 | 3,790 | 0 | — | -3,790 |
| KEROS THERAPEUTICS INC(KROS) | 101,050 | 104,323 | +3,273 | 5,868 | 1,651 | 0.13% | -4,217 |
| IQVIA HLDGS INC(IQV) | 111,854 | 111,854 | 0 | 26,506 | 21,980 | 1.67% | -4,526 |
| DAY ONE BIOPHARMACEUTICALS I COM | 342,172 | 0 | -342,172 | 4,766 | 0 | — | -4,766 |
| SYNDAX PHARMACEUTICALS INC(SNDX) | 423,910 | 206,871 | -217,039 | 8,160 | 2,735 | 0.21% | -5,425 |
| UNITEDHEALTH GROUP INC(UNH) | 75,588 | 75,588 | 0 | 44,195 | 38,237 | 2.91% | -5,958 |
| DANAHER CORPORATION(DHR) | 125,515 | 125,515 | 0 | 34,896 | 28,812 | 2.19% | -6,084 |
| ASCENDIS PHARMA A/S(ASND) | 90,766 | 52,392 | -38,374 | 13,552 | 7,213 | 0.55% | -6,339 |
| ICON PLC(ICLR) | 116,532 | 128,637 | +12,105 | 33,481 | 26,976 | 2.05% | -6,504 |
| OSCAR HEALTH INC(OSCR) | 860,821 | 860,821 | 0 | 18,258 | 11,569 | 0.88% | -6,689 |
| CONCENTRA GROUP HOLDINGS PAR(CON) | 300,000 | 0 | -300,000 | 6,708 | 0 | — | -6,708 |
| ADAPTIMMUNE THERAPEUTICS PLC(ADAPY) | 10,000,787 | 4,871,969 | -5,128,818 | 9,505 | 2,625 | 0.20% | -6,880 |
| ARGENX SE(ARGX) | 86,832 | 63,699 | -23,133 | 47,070 | 39,175 | 2.98% | -7,895 |
| INSMED INC(INSM) | 152,228 | 43,774 | -108,454 | 11,113 | 3,022 | 0.23% | -8,090 |
| CELCUITY INC(CELC) | 710,255 | 158,746 | -551,509 | 10,590 | 2,078 | 0.16% | -8,512 |
| BOSTON SCIENTIFIC CORP(BSX) | 108,469 | 0 | -108,469 | 9,090 | 0 | — | -9,090 |
| UNIVERSAL HLTH SVCS INC(UHS) | 213,983 | 213,983 | 0 | 49,004 | 38,393 | 2.92% | -10,611 |
| HUMANA INC(HUM) | 101,954 | 83,037 | -18,917 | 32,293 | 21,067 | 1.60% | -11,226 |
| SPDR SER TR ST STR SP BIOT | 121,845 | 0 | -121,845 | 12,038 | 0 | — | -12,038 |
| STRYKER CORPORATION(SYK) | 67,014 | 32,349 | -34,665 | 24,209 | 11,647 | 0.89% | -12,562 |
| ESSA PHARMA INC | 2,742,936 | 0 | -2,742,936 | 16,622 | 0 | — | -16,622 |
| VERTEX PHARMACEUTICALS INC(VRTX) | 148,852 | 126,989 | -21,863 | 69,228 | 51,138 | 3.90% | -18,090 |
| INTUITIVE SURGICAL INC | 137,327 | 93,073 | -44,254 | 67,465 | 48,580 | 3.70% | -18,884 |
| INSPIRE MED SYS INC(INSP) | 98,322 | 0 | -98,322 | 20,751 | 0 | — | -20,751 |
| ABBVIE INC(ABBV) | 403,861 | 331,741 | -72,120 | 79,754 | 58,950 | 4.49% | -20,804 |
| BECTON DICKINSON & CO(BDX) | 101,680 | 0 | -101,680 | 24,515 | 0 | — | -24,515 |
| THERMO FISHER SCIENTIFIC INC(TMO) | 58,433 | 21,040 | -37,393 | 36,145 | 10,946 | 0.83% | -25,199 |
| AMGEN INC(AMGN) | 90,297 | 0 | -90,297 | 29,095 | 0 | — | -29,095 |
| ELEVANCE HEALTH INC(ELV) | 56,441 | 0 | -56,441 | 29,349 | 0 | — | -29,349 |
| HCA HEALTHCARE INC(HCA) | 124,840 | 69,441 | -55,399 | 50,739 | 20,843 | 1.59% | -29,896 |
| ELI LILLY & CO(LLY) | 298,643 | 298,643 | 0 | 264,580 | 230,552 | 17.56% | -34,027 |
| TENET HEALTHCARE CORP(THC) | 589,409 | 491,334 | -98,075 | 97,960 | 62,021 | 4.72% | -35,939 |
| ACADIA HEALTHCARE COMPANY IN(ACHC) | 686,150 | 0 | -686,150 | 43,509 | 0 | — | -43,509 |
| MERCK & CO INC(MRK) | 542,811 | 0 | -542,811 | 61,642 | 0 | — | -61,642 |
| CYTOKINETICS INC(CYTK) | 1,757,192 | 0 | -1,757,192 | 92,780 | 0 | — | -92,780 |