Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q1 2026 ▲▼ | Q2 2026 ▲▼ | Change ▲▼ | Q1 2026 ▲▼ | Q2 2026 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| KAILERA THERAPEUTICS INC | 0 | 10,776,820 | +10,776,820 | 0 | 237,413 | 2.03% | +237,413 |
| ORUKA THERAPEUTICS INC(ORKA) | 2,058,148 | 3,139,030 | +1,080,882 | 100,952 | 298,741 | 2.55% | +197,789 |
| ULTRAGENYX PHARMACEUTICAL IN(RARE) | 3,648,795 | 7,796,895 | +4,148,100 | 76,442 | 260,338 | 2.22% | +183,896 |
| SPYRE THERAPEUTICS INC(SYRE) | 4,171,996 | 4,251,996 | +80,000 | 210,435 | 377,492 | 3.22% | +167,057 |
| TANGO THERAPEUTICS INC(TNGX) | 13,300,620 | 13,900,620 | +600,000 | 278,249 | 434,533 | 3.71% | +156,284 |
| ARGENX SE(ARGX) | 709,446 | 709,446 | 0 | 518,073 | 658,203 | 5.62% | +140,130 |
| UNIQURE NV(QURE) | 2,586,356 | 3,941,572 | +1,355,216 | 42,287 | 181,549 | 1.55% | +139,262 |
| CG ONCOLOGY INC(CGON) | 6,984,808 | 8,514,590 | +1,529,782 | 472,732 | 604,962 | 5.16% | +132,230 |
| PTC THERAPEUTICS INC(PTCT) | 7,746,415 | 7,746,415 | 0 | 527,763 | 631,875 | 5.39% | +104,112 |
| COMPASS PATHWAYS PLC(CMPS) | 10,632,390 | 10,700,974 | +68,584 | 58,797 | 151,419 | 1.29% | +92,622 |
| PROTAGONIST THERAPEUTICS INC | 5,059,053 | 5,061,175 | +2,122 | 533,224 | 620,399 | 5.30% | +87,175 |
| STRUCTURE THERAPEUTICS INC | 0 | 1,607,507 | +1,607,507 | 0 | 86,275 | 0.74% | +86,275 |
| UROGEN PHARMA LTD(URGN) | 4,543,895 | 4,543,895 | 0 | 81,699 | 167,215 | 1.43% | +85,516 |
| GUARDANT HEALTH INC(GH) | 1,481,033 | 1,481,033 | 0 | 136,803 | 222,199 | 1.90% | +85,396 |
| ESTABLISHMENT LABS HLDGS INC(ESTA) | 2,655,695 | 2,655,695 | 0 | 150,790 | 227,885 | 1.95% | +77,095 |
| GH RESEARCH PLC(GHRS) | 5,933,815 | 5,933,815 | 0 | 83,429 | 159,501 | 1.36% | +76,072 |
| NEUROCRINE BIOSCIENCES INC(NBIX) | 1,062,072 | 1,267,925 | +205,853 | 139,917 | 213,690 | 1.82% | +73,772 |
| ERASCA INC(ERAS) | 16,157,175 | 17,946,754 | +1,789,579 | 261,423 | 328,785 | 2.81% | +67,361 |
| CYTOKINETICS INC(CYTK) | 2,721,158 | 2,862,003 | +140,845 | 179,352 | 243,814 | 2.08% | +64,463 |
| IRHYTHM HOLDINGS INC(IRTC) | 1,668,500 | 2,182,631 | +514,131 | 196,916 | 259,624 | 2.22% | +62,708 |
| RADNET INC(RDNT) | 4,285,000 | 4,846,958 | +561,958 | 239,489 | 298,912 | 2.55% | +59,423 |
| AXOGEN INC(AXGN) | 0 | 1,011,576 | +1,011,576 | 0 | 46,725 | 0.40% | +46,725 |
| DANAHER CORP DEL(DHR) | 0 | 230,000 | +230,000 | 0 | 43,810 | 0.37% | +43,810 |
| IMMUNOVANT INC(IMVT) | 3,177,849 | 3,177,849 | 0 | 78,938 | 122,443 | 1.05% | +43,505 |
| SOLID BIOSCIENCES INC | 0 | 3,892,926 | +3,892,926 | 0 | 38,890 | 0.33% | +38,890 |
| CANDEL THERAPEUTICS INC | 6,422,018 | 6,422,018 | 0 | 31,468 | 66,147 | 0.56% | +34,679 |
| TAYSHA GENE THERAPIES INC(TSHA) | 13,680,248 | 13,560,258 | -119,990 | 61,151 | 92,345 | 0.79% | +31,195 |
| ALKERMES PLC(ALKS) | 1,672,356 | 1,672,356 | 0 | 59,135 | 87,623 | 0.75% | +28,489 |
| XENCOR INC(XNCR) | 6,777,461 | 6,777,461 | 0 | 81,736 | 109,117 | 0.93% | +27,381 |
| REPLIGEN CORP(RGEN) | 1,206,000 | 1,240,637 | +34,637 | 142,091 | 169,273 | 1.45% | +27,182 |
| MADRIGAL PHARMACEUTICALS INC(MDGL) | 1,993,687 | 1,993,687 | 0 | 1,043,635 | 1,070,510 | 9.14% | +26,875 |
| REPLIMUNE GROUP INC(REPL) | 7,356,916 | 7,411,581 | +54,665 | 56,280 | 82,046 | 0.70% | +25,766 |
| AKTIS ONCOLOGY INC(AKTS) | 1,592,043 | 1,592,043 | 0 | 28,482 | 51,312 | 0.44% | +22,830 |
| ACADIA PHARMACEUTICALS INC | 7,144,524 | 7,144,524 | 0 | 159,037 | 180,756 | 1.54% | +21,719 |
| NATERA INC(NTRA) | 1,250,000 | 1,000,000 | -250,000 | 249,988 | 271,450 | 2.32% | +21,463 |
| CULLINAN THERAPEUTICS INC(CGEM) | 1,705,960 | 2,364,347 | +658,387 | 24,242 | 43,055 | 0.37% | +18,813 |
| NEUROGENE INC | 1,362,456 | 1,362,456 | 0 | 27,467 | 42,849 | 0.37% | +15,382 |
| IDEAYA BIOSCIENCES INC(IDYA) | 0 | 370,370 | +370,370 | 0 | 13,804 | 0.12% | +13,804 |
| DEFINIUM THERAPEUTICS INC(DFTX) | 300,000 | 400,000 | +100,000 | 5,670 | 18,816 | 0.16% | +13,146 |
| IMMUNOCORE HLDGS PLC(IMCR) | 4,869,798 | 4,869,798 | 0 | 146,824 | 154,616 | 1.32% | +7,792 |
| KYMERA THERAPEUTICS INC(KYMR) | 240,000 | 240,000 | 0 | 19,990 | 27,521 | 0.23% | +7,531 |
| ALLOGENE THERAPEUTICS INC | 0 | 3,250,000 | +3,250,000 | 0 | 6,760 | 0.06% | +6,760 |
| MAZE THERAPEUTICS INC(MAZE) | 0 | 212,000 | +212,000 | 0 | 6,326 | 0.05% | +6,326 |
| BEAM THERAPEUTICS INC(BEAM) | 570,394 | 570,394 | 0 | 13,592 | 19,576 | 0.17% | +5,983 |
| ORCHESTRA BIOMED HLDGS INC | 8,306,063 | 9,556,063 | +1,250,000 | 35,301 | 41,234 | 0.35% | +5,934 |
| IMMATICS N.V(IMTX) | 12,869,340 | 12,946,176 | +76,836 | 126,634 | 131,145 | 1.12% | +4,510 |
| TENAX THERAPEUTICS INC | 370,246 | 696,570 | +326,324 | 5,920 | 10,135 | 0.09% | +4,215 |
| SAVARA INC(SVRA) | 5,952,380 | 5,952,380 | 0 | 32,500 | 36,667 | 0.31% | +4,167 |
| ABIVAX SA(ABVX) | 0 | 26,400 | +26,400 | 0 | 3,518 | 0.03% | +3,518 |
| BETA BIONICS INC | 2,000,000 | 1,500,000 | -500,000 | 20,040 | 23,505 | 0.20% | +3,465 |
| ATAIBECKLEY INC(ATAI) | 2,000,000 | 2,000,000 | 0 | 7,080 | 10,540 | 0.09% | +3,460 |
| DIANTHUS THERAPEUTICS INC(DNTH) | 248,063 | 248,063 | 0 | 20,817 | 24,181 | 0.21% | +3,364 |
| MILESTONE PHARMACEUTICALS IN | 6,331,001 | 7,833,336 | +1,502,335 | 7,534 | 10,497 | 0.09% | +2,963 |
| 4D MOLECULAR THERAPEUTICS IN | 475,737 | 475,737 | 0 | 4,429 | 6,327 | 0.05% | +1,898 |
| LUMEXA IMAGING HOLDINGS INC(LMRI) | 650,000 | 650,000 | 0 | 5,590 | 7,332 | 0.06% | +1,742 |
| CENTURY THERAPEUTICS INC | 8,695,652 | 8,695,652 | 0 | 19,652 | 21,304 | 0.18% | +1,652 |
| KODIAK SCIENCES INC(KOD) | 1,487,934 | 1,487,934 | 0 | 56,720 | 57,970 | 0.49% | +1,250 |
| ZAI LAB LTD(ZLAB) | 6,574,032 | 6,574,032 | 0 | 123,658 | 124,907 | 1.07% | +1,249 |
| LARIMAR THERAPEUTICS INC | 1,500,000 | 2,565,999 | +1,065,999 | 6,750 | 7,826 | 0.07% | +1,076 |
| STOKE THERAPEUTICS INC(STOK) | 5,623,525 | 5,623,525 | 0 | 183,102 | 184,002 | 1.57% | +900 |
| IMAGENEBIO INC | 334,445 | 334,445 | 0 | 1,672 | 1,973 | 0.02% | +301 |
| DISC MEDICINE INC(IRON) | 30,000 | 30,000 | 0 | 1,918 | 2,194 | 0.02% | +276 |
| AQUESTIVE THERAPEUTICS INC | 7,426,471 | 7,426,471 | 0 | 30,820 | 30,894 | 0.26% | +74 |
| ROCKET PHARMACEUTICALS INC | 350,000 | 350,000 | 0 | 7 | 1 | 0.00% | -6 |
| PERCEPTIVE CAP SOLUTIONS COR CL A ORD SHS | 742,500 | 742,500 | 0 | 8,145 | 8,078 | 0.07% | -67 |
| CRESCENT BIOPHARMA INC. | 372,856 | 372,856 | 0 | 6,849 | 6,711 | 0.06% | -138 |
| EXAGEN INC | 395,231 | 195,000 | -200,231 | 1,186 | 907 | 0.01% | -279 |
| MEDLINE INC(MDLN) | 70,000 | 70,000 | 0 | 3,115 | 2,761 | 0.02% | -354 |
| CELCUITY INC(CELC) | 3,039,621 | 3,304,903 | +265,282 | 346,942 | 345,759 | 2.95% | -1,183 |
| CASTLE BIOSCIENCES INC(CSTL) | 2,758,335 | 2,778,335 | +20,000 | 67,717 | 66,263 | 0.57% | -1,454 |
| CAPRICOR THERAPEUTICS INC | 250,000 | 250,000 | 0 | 7,600 | 6,020 | 0.05% | -1,580 |
| OCUGEN INC | 6,666,666 | 6,666,666 | 0 | 12,067 | 10,200 | 0.09% | -1,867 |
| WAVE LIFE SCIENCES LTD(WVE) | 1,350,000 | 1,350,000 | 0 | 9,788 | 7,844 | 0.07% | -1,944 |
| KALARIS THERAPEUTICS INC | 1,300,000 | 1,300,000 | 0 | 7,501 | 5,291 | 0.05% | -2,210 |
| OMADA HEALTH INC(OMDA) | 200,000 | 0 | -200,000 | 2,514 | 0 | — | -2,514 |
| ROCKET PHARMACEUTICALS INC | 17,687,772 | 17,687,772 | 0 | 63,322 | 60,492 | 0.52% | -2,830 |
| HEARTFLOW INC(HTFL) | 495,000 | 295,000 | -200,000 | 12,043 | 8,655 | 0.07% | -3,388 |
| BELITE BIO INC(BLTE) | 715,332 | 715,332 | 0 | 114,053 | 110,150 | 0.94% | -3,902 |
| INVENTIVA SA(IVA) | 1,298,702 | 0 | -1,298,702 | 7,208 | 0 | — | -7,208 |
| JADE BIOSCIENCES INC | 573,205 | 0 | -573,205 | 8,054 | 0 | — | -8,054 |
| VERASTEM INC | 6,576,306 | 6,635,793 | +59,487 | 34,854 | 25,349 | 0.22% | -9,506 |
| AVALO THERAPEUTICS INC(AVTX) | 856,962 | 175,000 | -681,962 | 12,794 | 3,234 | 0.03% | -9,560 |
| EVOMMUNE INC | 1,502,235 | 1,502,235 | 0 | 34,536 | 19,965 | 0.17% | -14,572 |
| FULGENT GENETICS INC | 1,289,000 | 0 | -1,289,000 | 20,495 | 0 | — | -20,495 |
| COMPASS THERAPEUTICS INC | 4,186,599 | 0 | -4,186,599 | 22,147 | 0 | — | -22,147 |
| TARSUS PHARMACEUTICALS INC(TARS) | 3,346,025 | 3,357,059 | +11,034 | 234,724 | 211,293 | 1.80% | -23,430 |
| STRYKER CORPORATION(SYK) | 100,000 | 0 | -100,000 | 32,859 | 0 | — | -32,859 |
| HINGE HEALTH INC(HNGE) | 1,930,000 | 500,000 | -1,430,000 | 74,421 | 41,500 | 0.35% | -32,921 |
| ARROWHEAD PHARMACEUTICALS IN(ARWR) | 585,682 | 0 | -585,682 | 36,722 | 0 | — | -36,722 |
| WAYSTAR HLDG CORP(WAY) | 1,630,000 | 0 | -1,630,000 | 39,299 | 0 | — | -39,299 |
| CRINETICS PHARMACEUTICALS IN(CRNX) | 1,451,326 | 0 | -1,451,326 | 52,712 | 0 | — | -52,712 |
| CENTESSA PHARMACEUTICALS PLC | 2,054,175 | 0 | -2,054,175 | 81,592 | 0 | — | -81,592 |
| INTUITIVE SURGICAL INC | 220,000 | 0 | -220,000 | 101,418 | 0 | — | -101,418 |
| COGENT BIOSCIENCES INC(COGT) | 5,458,675 | 2,309,021 | -3,149,654 | 210,104 | 89,359 | 0.76% | -120,745 |
| APELLIS PHARMACEUTICALS INC COM | 3,685,045 | 0 | -3,685,045 | 148,249 | 0 | — | -148,249 |
| APOGEE THERAPEUTICS INC(APGE) | 2,782,097 | 0 | -2,782,097 | 234,169 | 0 | — | -234,169 |
| INSMED INC(INSM) | 4,842,880 | 4,842,880 | 0 | 791,908 | 516,348 | 4.41% | -275,560 |