Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q1 2024 ▲▼ | Q2 2024 ▲▼ | Change ▲▼ | Q1 2024 ▲▼ | Q2 2024 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Madrigal Pharmaceuticals, Inc.(MDGL) | 397,047 | 1,915,862 | +1,518,815 | $106.03M | $536.75M | 8.31% | +$430.72M |
| Rocket Pharmaceuticals, Inc.(RCKT) | 17,687,772 | 17,687,772 | 0 | $476.51M | $380.82M | 5.90% | -$95.69M |
| Axsome Therapeutics, Inc.(AXSM) | 4,492,679 | 4,634,331 | +141,652 | $358.52M | $373.06M | 5.78% | +$14.55M |
| Avidity Biosciences Inc | 7,970,269 | 8,806,838 | +836,569 | $203.40M | $359.76M | 5.57% | +$156.36M |
| argenx SEADR(ARGX) | 667,195 | 654,430 | -12,765 | $262.69M | $281.43M | 4.36% | +$18.74M |
| Natera, Inc.(NTRA) | 2,593,323 | 2,593,323 | 0 | $237.19M | $280.83M | 4.35% | +$43.65M |
| Merus N V | 4,109,393 | 4,169,393 | +60,000 | $185.05M | $246.70M | 3.82% | +$61.66M |
| Insmed Incorporated(INSM) | 1,865,108 | 3,640,108 | +1,775,000 | $50.60M | $243.89M | 3.78% | +$193.29M |
| PTC Therapeutics, Inc.(PTCT) | 7,423,970 | 7,393,127 | -30,843 | $215.96M | $226.08M | 3.50% | +$10.12M |
| Dyne Therapeutics, Inc.(DYN) | 3,091,587 | 6,387,138 | +3,295,551 | $87.77M | $225.40M | 3.49% | +$137.63M |
| Acadia Pharmaceuticals Inc | 13,829,315 | 13,707,506 | -121,809 | $255.70M | $222.75M | 3.45% | -$32.96M |
| Bruker Corporation(BRKR) | 3,344,095 | 3,444,095 | +100,000 | $314.14M | $219.77M | 3.40% | -$94.38M |
| Masimo Corp | 1,462,400 | 1,462,400 | 0 | $214.75M | $184.17M | 2.85% | -$30.58M |
| Protagonist Therapeutics Inc | 5,315,514 | 5,286,404 | -29,110 | $153.78M | $183.17M | 2.84% | +$29.40M |
| Alkermes plcSHS(ALKS) | 6,054,280 | 7,056,988 | +1,002,708 | $163.89M | $170.07M | 2.63% | +$6.18M |
| Immunocore Holdings plcADS(IMCR) | 6,019,641 | 4,869,798 | -1,149,843 | $391.28M | $165.04M | 2.56% | -$226.24M |
| Cytokinetics, Incorporated(CYTK) | 2,525,080 | 2,721,158 | +196,078 | $177.03M | $147.43M | 2.28% | -$29.60M |
| Ultragenyx Pharmaceutical Inc.(RARE) | 7,087,115 | 3,259,927 | -3,827,188 | $330.90M | $133.98M | 2.07% | -$196.91M |
| Penumbra, Inc.(PEN) | 675,888 | 742,105 | +66,217 | $150.84M | $133.56M | 2.07% | -$17.29M |
| Akero Therapeutics Inc | 5,431,985 | 5,431,985 | 0 | $137.21M | $127.43M | 1.97% | -$9.78M |
| Establishment Labs Holdings Inc.(ESTA) | 2,675,703 | 2,675,703 | 0 | $136.19M | $121.58M | 1.88% | -$14.61M |
| Immatics N.V.SHS(IMTX) | 10,000,000 | 10,000,000 | 0 | $105.10M | $116.20M | 1.80% | +$11.10M |
| RadNet, Inc.(RDNT) | 1,700,550 | 1,856,010 | +155,460 | $82.75M | $109.36M | 1.69% | +$26.61M |
| Apogee Therapeutics Inc | 2,467,591 | 2,712,096 | +244,505 | $163.97M | $106.72M | 1.65% | -$57.25M |
| Tarsus Pharmaceuticals, Inc.(TARS) | 3,272,341 | 3,412,486 | +140,145 | $118.95M | $92.75M | 1.44% | -$26.20M |
| Intuitive Surgical, Inc.(ISRG) | 99,000 | 202,456 | +103,456 | $39.51M | $90.06M | 1.39% | +$50.55M |
| Arvinas, Inc.(ARVN) | 3,297,897 | 2,967,897 | -330,000 | $136.14M | $79.01M | 1.22% | -$57.13M |
| Spyre Therapeutics, Inc.(SYRE) | 2,232,760 | 3,258,360 | +1,025,600 | $84.69M | $76.60M | 1.19% | -$8.08M |
| Cargo Therapeutics Inc | 3,735,619 | 4,078,122 | +342,503 | $83.38M | $66.96M | 1.04% | -$16.42M |
| UroGen Pharma Ltd.(URGN) | 3,257,347 | 3,557,347 | +300,000 | $48.86M | $59.69M | 0.92% | +$10.83M |
| Sage Therapeutics Inc | 5,480,577 | 5,480,577 | 0 | $102.71M | $59.52M | 0.92% | -$43.19M |
| 89bio Inc | 7,378,548 | 7,378,548 | 0 | $85.89M | $59.10M | 0.92% | -$26.78M |
| Stoke Therapeutics, Inc.(STOK) | 4,224,838 | 4,224,838 | 0 | $57.04M | $57.08M | 0.88% | +$42.2K |
| Orchestra BioMed Holdings, Inc.(OBIO) | 5,620,640 | 5,620,640 | 0 | $29.62M | $45.81M | 0.71% | +$16.19M |
| Glaukos Corporation(GKOS) | 58,791 | 386,291 | +327,500 | $5.54M | $45.72M | 0.71% | +$40.17M |
| CG Oncology, Inc.(CGON) | 413,670 | 1,344,074 | +930,404 | $18.16M | $42.43M | 0.66% | +$24.27M |
| Taysha Gene Therapies, Inc.(TSHA) | 18,593,185 | 18,800,299 | +207,114 | $53.36M | $42.11M | 0.65% | -$11.25M |
| Neurogene Inc.(NGNE) | 769,122 | 1,070,565 | +301,443 | $39.15M | $38.96M | 0.60% | -$190.4K |
| GH Research PLC(GHRS) | 3,327,129 | 3,327,129 | 0 | $35.47M | $38.79M | 0.60% | +$3.33M |
| Vericel Corporation(VCEL) | 1,606,397 | 801,397 | -805,000 | $83.56M | $36.77M | 0.57% | -$46.80M |
| Fulcrum Therapeutics, Inc.(FULC) | 5,845,956 | 5,845,956 | 0 | $55.19M | $36.24M | 0.56% | -$18.94M |
| Cullinan Therapeutics, Inc.(CGEM) | 0 | 1,052,630 | +1,052,630 | $0 | $18.36M | 0.28% | +$18.36M |
| Dianthus Therapeutics, Inc.(DNTH) | 666,667 | 666,667 | 0 | $20.00M | $17.25M | 0.27% | -$2.75M |
| Roivant Sciences Ltd.SHS(ROIV) | 1,454,273 | 1,454,273 | 0 | $15.33M | $15.37M | 0.24% | +$43.6K |
| LENZ Therapeutics, Inc.(LENZ) | 863,389 | 863,389 | 0 | $19.28M | $14.93M | 0.23% | -$4.35M |
| Tempus AI, Inc.CL A(TEM) | 0 | 400,000 | +400,000 | $0 | $14.00M | 0.22% | +$14.00M |
| Kyverna Therapeutics, Inc.(KYTX) | 1,852,711 | 1,852,711 | 0 | $46.02M | $13.90M | 0.22% | -$32.13M |
| Essa Pharma Inc | 2,298,662 | 2,298,662 | 0 | $19.52M | $12.09M | 0.19% | -$7.42M |
| Replimune Group, Inc.(REPL) | 0 | 1,133,787 | +1,133,787 | $0 | $10.20M | 0.16% | +$10.20M |
| 10x Genomics, Inc.CL A(TXG) | 1,554,856 | 502,856 | -1,052,000 | $58.35M | $9.78M | 0.15% | -$48.57M |
| Tourmaline Bio Inc | 741,656 | 741,656 | 0 | $16.98M | $9.54M | 0.15% | -$7.45M |
| Viridian Therapeutics, Inc.(VRDN) | 605,816 | 605,816 | 0 | $10.61M | $7.88M | 0.12% | -$2.73M |
| Perceptive Cap Solutions CorCL A CL A ORD SHS | 0 | 742,500 | +742,500 | $0 | $7.47M | 0.12% | +$7.47M |
| Arca Biopharma Inc | 0 | 1,400,000 | +1,400,000 | $0 | $5.36M | 0.08% | +$5.36M |
| Immunic, Inc.(IMUX) | 4,567,717 | 4,567,717 | 0 | $6.03M | $5.07M | 0.08% | -$959.2K |
| Structure Therapeutics IncADS | 0 | 125,000 | +125,000 | $0 | $4.91M | 0.08% | +$4.91M |
| Acelyrin Inc | 978,310 | 978,310 | 0 | $6.60M | $4.31M | 0.07% | -$2.29M |
| Milestone Pharmaceuticals Inc.(MIST) | 3,256,102 | 3,256,102 | 0 | $5.83M | $4.30M | 0.07% | -$1.53M |
| REGENXBIO Inc.(RGNX) | 350,000 | 350,000 | 0 | $7.37M | $4.09M | 0.06% | -$3.28M |
| Allurion Technologies Inc | 3,457,707 | 3,697,549 | +239,842 | $6.05M | $3.69M | 0.06% | -$2.36M |
| Exagen Inc.(XGN) | 1,504,602 | 1,511,866 | +7,264 | $2.39M | $2.75M | 0.04% | +$359.3K |
| SAB Biotherapeutics, Inc.(SABS) | 917,827 | 766,946 | -150,881 | $4.17M | $2.38M | 0.04% | -$1.79M |
| Cutera Inc | 1,331,776 | 1,331,776 | 0 | $1.96M | $2.01M | 0.03% | +$53.3K |
| Sagimet Biosciences Inc.COM SER A(SGMT) | 999,147 | 500,000 | -499,147 | $5.42M | $1.71M | 0.03% | -$3.71M |
| Arya Sciences Acqu Corp IvCL A | 127,970 | 127,970 | 0 | $1.44M | $1.47M | 0.02% | +$30.7K |
| CytomX Therapeutics, Inc.(CTMX) | 0 | 1,200,002 | +1,200,002 | $0 | $1.46M | 0.02% | +$1.46M |
| Adicet Bio Inc | 4,134,631 | 1,053,688 | -3,080,943 | $9.72M | $1.27M | 0.02% | -$8.44M |
| Rocket Pharmaceuticals, Inc.W EXP 09 02 202(RCKT) | 350,000 | 350,000 | 0 | $104.7K | $21.2K | 0.00% | -$83.5K |
| Avadel Pharmaceuticals PlcADR | 8,798,558 | 0 | -8,798,558 | $148.61M | $0 | — | -$148.61M |
| Beyond Air, Inc.(XAIR) | 1,204,820 | 0 | -1,204,820 | $2.10M | $0 | — | -$2.10M |
| Endeavour Silver Corp.(EXK) | 95,000 | 0 | -95,000 | $6.56M | $0 | — | -$6.56M |
| Janux Therapeutics, Inc.(JANX) | 1,000,000 | 0 | -1,000,000 | $37.65M | $0 | — | -$37.65M |
| Larimar Therapeutics, Inc.(LRMR) | 650,000 | 0 | -650,000 | $4.93M | $0 | — | -$4.93M |
| Shockwave Med Inc | 288,684 | 0 | -288,684 | $94.00M | $0 | — | -$94.00M |
| Stryker Corporation(SYK) | 321,000 | 0 | -321,000 | $114.88M | $0 | — | -$114.88M |
| Thermo Fisher Scientific Inc.(TMO) | 110,500 | 0 | -110,500 | $64.22M | $0 | — | -$64.22M |