Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q1 2026 ▲▼ | Q2 2026 ▲▼ | Change ▲▼ | Q1 2026 ▲▼ | Q2 2026 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Madrigal Pharmaceuticals, Inc.(MDGL) | 1,993,687 | 1,993,687 | 0 | $1.04B | $1.07B | 9.14% | +$26.87M |
| argenx SEADR(ARGX) | 709,446 | 709,446 | 0 | $518.07M | $658.20M | 5.62% | +$140.13M |
| PTC Therapeutics, Inc.(PTCT) | 7,746,415 | 7,746,415 | 0 | $527.76M | $631.88M | 5.39% | +$104.11M |
| Protagonist Therapeutics Inc | 5,059,053 | 5,061,175 | +2,122 | $533.22M | $620.40M | 5.30% | +$87.17M |
| CG Oncology, Inc.(CGON) | 6,984,808 | 8,514,590 | +1,529,782 | $472.73M | $604.96M | 5.16% | +$132.23M |
| Insmed Incorporated(INSM) | 4,842,880 | 4,842,880 | 0 | $791.91M | $516.35M | 4.41% | -$275.56M |
| Tango Therapeutics, Inc.(TNGX) | 13,300,620 | 13,900,620 | +600,000 | $278.25M | $434.53M | 3.71% | +$156.28M |
| Spyre Therapeutics, Inc.(SYRE) | 4,171,996 | 4,251,996 | +80,000 | $210.44M | $377.49M | 3.22% | +$167.06M |
| Celcuity Inc.(CELC) | 3,039,621 | 3,304,903 | +265,282 | $346.94M | $345.76M | 2.95% | -$1.18M |
| Erasca, Inc.(ERAS) | 16,157,175 | 17,946,754 | +1,789,579 | $261.42M | $328.78M | 2.81% | +$67.36M |
| RadNet, Inc.(RDNT) | 4,285,000 | 4,846,958 | +561,958 | $239.49M | $298.91M | 2.55% | +$59.42M |
| Oruka Therapeutics, Inc.(ORKA) | 2,058,148 | 3,139,030 | +1,080,882 | $100.95M | $298.74M | 2.55% | +$197.79M |
| Natera, Inc.(NTRA) | 1,250,000 | 1,000,000 | -250,000 | $249.99M | $271.45M | 2.32% | +$21.46M |
| Ultragenyx Pharmaceutical Inc.(RARE) | 3,648,795 | 7,796,895 | +4,148,100 | $76.44M | $260.34M | 2.22% | +$183.90M |
| iRhythm Holdings, Inc.(IRTC) | 1,668,500 | 2,182,631 | +514,131 | $196.92M | $259.62M | 2.22% | +$62.71M |
| Cytokinetics, Incorporated(CYTK) | 2,721,158 | 2,862,003 | +140,845 | $179.35M | $243.81M | 2.08% | +$64.46M |
| Kailera Therapeutics Inc | 0 | 10,776,820 | +10,776,820 | $0 | $237.41M | 2.03% | +$237.41M |
| Establishment Labs Holdings Inc.(ESTA) | 2,655,695 | 2,655,695 | 0 | $150.79M | $227.89M | 1.95% | +$77.09M |
| Guardant Health, Inc.(GH) | 1,481,033 | 1,481,033 | 0 | $136.80M | $222.20M | 1.90% | +$85.40M |
| Neurocrine Biosciences, Inc.(NBIX) | 1,062,072 | 1,267,925 | +205,853 | $139.92M | $213.69M | 1.82% | +$73.77M |
| Tarsus Pharmaceuticals, Inc.(TARS) | 3,346,025 | 3,357,059 | +11,034 | $234.72M | $211.29M | 1.80% | -$23.43M |
| Stoke Therapeutics, Inc.(STOK) | 5,623,525 | 5,623,525 | 0 | $183.10M | $184.00M | 1.57% | +$899.8K |
| uniQure N.V.SHS(QURE) | 2,586,356 | 3,941,572 | +1,355,216 | $42.29M | $181.55M | 1.55% | +$139.26M |
| Acadia Pharmaceuticals Inc | 7,144,524 | 7,144,524 | 0 | $159.04M | $180.76M | 1.54% | +$21.72M |
| Repligen Corporation(RGEN) | 1,206,000 | 1,240,637 | +34,637 | $142.09M | $169.27M | 1.45% | +$27.18M |
| UroGen Pharma Ltd.(URGN) | 4,543,895 | 4,543,895 | 0 | $81.70M | $167.22M | 1.43% | +$85.52M |
| GH Research PLC(GHRS) | 5,933,815 | 5,933,815 | 0 | $83.43M | $159.50M | 1.36% | +$76.07M |
| Immunocore Holdings plcADS(IMCR) | 4,869,798 | 4,869,798 | 0 | $146.82M | $154.62M | 1.32% | +$7.79M |
| COMPASS Pathways plcADS(CMPS) | 10,632,390 | 10,700,974 | +68,584 | $58.80M | $151.42M | 1.29% | +$92.62M |
| Immatics N.V.SHS(IMTX) | 12,869,340 | 12,946,176 | +76,836 | $126.63M | $131.14M | 1.12% | +$4.51M |
| Zai Lab LimitedADR(ZLAB) | 6,574,032 | 6,574,032 | 0 | $123.66M | $124.91M | 1.07% | +$1.25M |
| Immunovant, Inc.(IMVT) | 3,177,849 | 3,177,849 | 0 | $78.94M | $122.44M | 1.05% | +$43.50M |
| Belite Bio, IncADS(BLTE) | 715,332 | 715,332 | 0 | $114.05M | $110.15M | 0.94% | -$3.90M |
| Xencor, Inc.(XNCR) | 6,777,461 | 6,777,461 | 0 | $81.74M | $109.12M | 0.93% | +$27.38M |
| Taysha Gene Therapies, Inc.(TSHA) | 13,680,248 | 13,560,258 | -119,990 | $61.15M | $92.35M | 0.79% | +$31.19M |
| Cogent Biosciences, Inc.(COGT) | 5,458,675 | 2,309,021 | -3,149,654 | $210.10M | $89.36M | 0.76% | -$120.75M |
| Alkermes plcSHS(ALKS) | 1,672,356 | 1,672,356 | 0 | $59.13M | $87.62M | 0.75% | +$28.49M |
| Structure Therapeutics IncADS | 0 | 1,607,507 | +1,607,507 | $0 | $86.27M | 0.74% | +$86.27M |
| Replimune Group, Inc.(REPL) | 7,356,916 | 7,411,581 | +54,665 | $56.28M | $82.05M | 0.70% | +$25.77M |
| Castle Biosciences, Inc.(CSTL) | 2,758,335 | 2,778,335 | +20,000 | $67.72M | $66.26M | 0.57% | -$1.45M |
| Candel Therapeutics, Inc.(CADL) | 6,422,018 | 6,422,018 | 0 | $31.47M | $66.15M | 0.56% | +$34.68M |
| Rocket Pharmaceuticals, Inc.(RCKT) | 17,687,772 | 17,687,772 | 0 | $63.32M | $60.49M | 0.52% | -$2.83M |
| Kodiak Sciences Inc.(KOD) | 1,487,934 | 1,487,934 | 0 | $56.72M | $57.97M | 0.49% | +$1.25M |
| Aktis Oncology, Inc.(AKTS) | 1,592,043 | 1,592,043 | 0 | $28.48M | $51.31M | 0.44% | +$22.83M |
| Axogen, Inc.(AXGN) | 0 | 1,011,576 | +1,011,576 | $0 | $46.72M | 0.40% | +$46.72M |
| Danaher Corporation(DHR) | 0 | 230,000 | +230,000 | $0 | $43.81M | 0.37% | +$43.81M |
| Cullinan Therapeutics, Inc.(CGEM) | 1,705,960 | 2,364,347 | +658,387 | $24.24M | $43.05M | 0.37% | +$18.81M |
| Neurogene Inc.(NGNE) | 1,362,456 | 1,362,456 | 0 | $27.47M | $42.85M | 0.37% | +$15.38M |
| Hinge Health, Inc.CL A(HNGE) | 1,930,000 | 500,000 | -1,430,000 | $74.42M | $41.50M | 0.35% | -$32.92M |
| Orchestra BioMed Holdings, Inc.(OBIO) | 8,306,063 | 9,556,063 | +1,250,000 | $35.30M | $41.23M | 0.35% | +$5.93M |
| Solid Biosciences Inc | 0 | 3,892,926 | +3,892,926 | $0 | $38.89M | 0.33% | +$38.89M |
| Savara Inc.(SVRA) | 5,952,380 | 5,952,380 | 0 | $32.50M | $36.67M | 0.31% | +$4.17M |
| Aquestive Therapeutics Inc | 7,426,471 | 7,426,471 | 0 | $30.82M | $30.89M | 0.26% | +$74.3K |
| Kymera Therapeutics, Inc.(KYMR) | 240,000 | 240,000 | 0 | $19.99M | $27.52M | 0.23% | +$7.53M |
| Verastem, Inc.(VSTM) | 6,576,306 | 6,635,793 | +59,487 | $34.85M | $25.35M | 0.22% | -$9.51M |
| Dianthus Therapeutics, Inc.(DNTH) | 248,063 | 248,063 | 0 | $20.82M | $24.18M | 0.21% | +$3.36M |
| Beta Bionics, Inc.(BBNX) | 2,000,000 | 1,500,000 | -500,000 | $20.04M | $23.50M | 0.20% | +$3.46M |
| Century Therapeutics, Inc.(IPSC) | 8,695,652 | 8,695,652 | 0 | $19.65M | $21.30M | 0.18% | +$1.65M |
| Evommune, Inc.(EVMN) | 1,502,235 | 1,502,235 | 0 | $34.54M | $19.96M | 0.17% | -$14.57M |
| Beam Therapeutics Inc.(BEAM) | 570,394 | 570,394 | 0 | $13.59M | $19.58M | 0.17% | +$5.98M |
| Definium Therapeutics, Inc.(DFTX) | 300,000 | 400,000 | +100,000 | $5.67M | $18.82M | 0.16% | +$13.15M |
| IDEAYA Biosciences, Inc.(IDYA) | 0 | 370,370 | +370,370 | $0 | $13.80M | 0.12% | +$13.80M |
| Ataibeckley Inc | 2,000,000 | 2,000,000 | 0 | $7.08M | $10.54M | 0.09% | +$3.46M |
| Milestone Pharmaceuticals Inc.(MIST) | 6,331,001 | 7,833,336 | +1,502,335 | $7.53M | $10.50M | 0.09% | +$2.96M |
| Ocugen, Inc.(OCGN) | 6,666,666 | 6,666,666 | 0 | $12.07M | $10.20M | 0.09% | -$1.87M |
| Tenax Therapeutics, Inc.(TENX) | 370,246 | 696,570 | +326,324 | $5.92M | $10.14M | 0.09% | +$4.21M |
| Heartflow, Inc.(HTFL) | 495,000 | 295,000 | -200,000 | $12.04M | $8.66M | 0.07% | -$3.39M |
| Perceptive Cap Solutions CorCL A CL A ORD SHS | 742,500 | 742,500 | 0 | $8.15M | $8.08M | 0.07% | -$66.8K |
| Wave Life Sciences, Inc.SHS(WVE) | 1,350,000 | 1,350,000 | 0 | $9.79M | $7.84M | 0.07% | -$1.94M |
| Larimar Therapeutics, Inc.(LRMR) | 1,500,000 | 2,565,999 | +1,065,999 | $6.75M | $7.83M | 0.07% | +$1.08M |
| Lumexa Imaging Holdings, Inc.(LMRI) | 650,000 | 650,000 | 0 | $5.59M | $7.33M | 0.06% | +$1.74M |
| Allogene Therapeutics Inc | 0 | 3,250,000 | +3,250,000 | $0 | $6.76M | 0.06% | +$6.76M |
| Crescent Biopharma, Inc.(CBIO) | 372,856 | 372,856 | 0 | $6.85M | $6.71M | 0.06% | -$138.0K |
| 4d Molecular Therapeutics In | 475,737 | 475,737 | 0 | $4.43M | $6.33M | 0.05% | +$1.90M |
| Maze Therapeutics, Inc.(MAZE) | 0 | 212,000 | +212,000 | $0 | $6.33M | 0.05% | +$6.33M |
| Capricor Therapeutics, Inc.(CAPR) | 250,000 | 250,000 | 0 | $7.60M | $6.02M | 0.05% | -$1.58M |
| Kalaris Therapeutics, Inc.(KLRS) | 1,300,000 | 1,300,000 | 0 | $7.50M | $5.29M | 0.05% | -$2.21M |
| ABIVAX Société AnonymeADS(ABVX) | 0 | 26,400 | +26,400 | $0 | $3.52M | 0.03% | +$3.52M |
| Avalo Therapeutics, Inc.(AVTX) | 856,962 | 175,000 | -681,962 | $12.79M | $3.23M | 0.03% | -$9.56M |
| Medline Inc.CL A(MDLN) | 70,000 | 70,000 | 0 | $3.12M | $2.76M | 0.02% | -$354.2K |
| Disc Medicine, Inc.(IRON) | 30,000 | 30,000 | 0 | $1.92M | $2.19M | 0.02% | +$276.0K |
| ImageneBio, Inc.(IMA) | 334,445 | 334,445 | 0 | $1.67M | $1.97M | 0.02% | +$301.0K |
| Exagen Inc.(XGN) | 395,231 | 195,000 | -200,231 | $1.19M | $906.8K | 0.01% | -$278.9K |
| Rocket Pharmaceuticals, Inc.W EXP 09 02 202(RCKT) | 350,000 | 350,000 | 0 | $7.2K | $1.2K | 0.00% | -$6.0K |
| Apellis Pharmaceuticals Inc COM | 3,685,045 | 0 | -3,685,045 | $148.25M | $0 | — | -$148.25M |
| Apogee Therapeutics Inc | 2,782,097 | 0 | -2,782,097 | $234.17M | $0 | — | -$234.17M |
| Arrowhead Pharmaceuticals, Inc.(ARWR) | 585,682 | 0 | -585,682 | $36.72M | $0 | — | -$36.72M |
| Centessa Pharmaceuticals PlcADS | 2,054,175 | 0 | -2,054,175 | $81.59M | $0 | — | -$81.59M |
| Compass Therapeutics, Inc.(CMPX) | 4,186,599 | 0 | -4,186,599 | $22.15M | $0 | — | -$22.15M |
| Crinetics Pharmaceuticals In | 1,451,326 | 0 | -1,451,326 | $52.71M | $0 | — | -$52.71M |
| Fulgent Genetics, Inc.(FLGT) | 1,289,000 | 0 | -1,289,000 | $20.50M | $0 | — | -$20.50M |
| Intuitive Surgical, Inc.(ISRG) | 220,000 | 0 | -220,000 | $101.42M | $0 | — | -$101.42M |
| Inventiva S.A.ADS(IVA) | 1,298,702 | 0 | -1,298,702 | $7.21M | $0 | — | -$7.21M |
| Jade Biosciences Inc | 573,205 | 0 | -573,205 | $8.05M | $0 | — | -$8.05M |
| Omada Health, Inc.(OMDA) | 200,000 | 0 | -200,000 | $2.51M | $0 | — | -$2.51M |
| Stryker Corporation(SYK) | 100,000 | 0 | -100,000 | $32.86M | $0 | — | -$32.86M |
| Waystar Holding Corp.(WAY) | 1,630,000 | 0 | -1,630,000 | $39.30M | $0 | — | -$39.30M |