Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q2 2024 ▲▼ | Q3 2024 ▲▼ | Change ▲▼ | Q2 2024 ▲▼ | Q3 2024 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Madrigal Pharmaceuticals, Inc.(MDGL) | 1,915,862 | 1,993,687 | +77,825 | $536.75M | $423.10M | 6.12% | -$113.65M |
| Axsome Therapeutics, Inc.(AXSM) | 4,634,331 | 4,189,557 | -444,774 | $373.06M | $376.52M | 5.45% | +$3.45M |
| Avidity Biosciences Inc | 8,806,838 | 8,132,870 | -673,968 | $359.76M | $373.54M | 5.40% | +$13.78M |
| argenx SEADR(ARGX) | 654,430 | 654,430 | 0 | $281.43M | $354.75M | 5.13% | +$73.32M |
| Natera, Inc.(NTRA) | 2,593,323 | 2,593,323 | 0 | $280.83M | $329.22M | 4.76% | +$48.39M |
| Rocket Pharmaceuticals, Inc.(RCKT) | 17,687,772 | 17,687,772 | 0 | $380.82M | $326.69M | 4.73% | -$54.12M |
| PTC Therapeutics, Inc.(PTCT) | 7,393,127 | 7,393,127 | 0 | $226.08M | $274.29M | 3.97% | +$48.20M |
| Dyne Therapeutics, Inc.(DYN) | 6,387,138 | 6,818,641 | +431,503 | $225.40M | $244.93M | 3.54% | +$19.52M |
| Protagonist Therapeutics Inc | 5,286,404 | 5,426,112 | +139,708 | $183.17M | $244.18M | 3.53% | +$61.00M |
| Bruker Corporation(BRKR) | 3,444,095 | 3,481,119 | +37,024 | $219.77M | $240.41M | 3.48% | +$20.64M |
| Insmed Incorporated(INSM) | 3,640,108 | 3,272,008 | -368,100 | $243.89M | $238.86M | 3.46% | -$5.03M |
| Acadia Pharmaceuticals Inc | 13,707,506 | 13,707,506 | 0 | $222.75M | $210.82M | 3.05% | -$11.93M |
| Merus N V | 4,169,393 | 4,169,393 | 0 | $246.70M | $208.30M | 3.01% | -$38.40M |
| Geron Corporation(GERN) | 0 | 44,111,916 | +44,111,916 | $0 | $200.27M | 2.90% | +$200.27M |
| Masimo Corp | 1,462,400 | 1,462,400 | 0 | $184.17M | $194.98M | 2.82% | +$10.81M |
| Alkermes plcSHS(ALKS) | 7,056,988 | 6,654,033 | -402,955 | $170.07M | $186.25M | 2.69% | +$16.17M |
| Akero Therapeutics Inc | 5,431,985 | 5,919,435 | +487,450 | $127.43M | $169.83M | 2.46% | +$42.39M |
| Apogee Therapeutics Inc | 2,712,096 | 2,712,096 | 0 | $106.72M | $159.31M | 2.31% | +$52.59M |
| Penumbra, Inc.(PEN) | 742,105 | 795,750 | +53,645 | $133.56M | $154.62M | 2.24% | +$21.07M |
| Immunocore Holdings plcADS(IMCR) | 4,869,798 | 4,869,798 | 0 | $165.04M | $151.60M | 2.19% | -$13.44M |
| Cytokinetics, Incorporated(CYTK) | 2,721,158 | 2,721,158 | 0 | $147.43M | $143.68M | 2.08% | -$3.76M |
| Stryker Corporation(SYK) | 0 | 396,921 | +396,921 | $0 | $143.39M | 2.07% | +$143.39M |
| RadNet, Inc.(RDNT) | 1,856,010 | 1,808,604 | -47,406 | $109.36M | $125.50M | 1.82% | +$16.14M |
| Establishment Labs Holdings Inc.(ESTA) | 2,675,703 | 2,645,703 | -30,000 | $121.58M | $114.48M | 1.66% | -$7.10M |
| Immatics N.V.SHS(IMTX) | 10,000,000 | 10,000,000 | 0 | $116.20M | $114.10M | 1.65% | -$2.10M |
| Tarsus Pharmaceuticals, Inc.(TARS) | 3,412,486 | 3,412,486 | 0 | $92.75M | $112.24M | 1.62% | +$19.49M |
| Ultragenyx Pharmaceutical Inc.(RARE) | 3,259,927 | 1,968,002 | -1,291,925 | $133.98M | $109.32M | 1.58% | -$24.66M |
| Spyre Therapeutics, Inc.(SYRE) | 3,258,360 | 3,258,360 | 0 | $76.60M | $95.83M | 1.39% | +$19.22M |
| Cargo Therapeutics Inc | 4,078,122 | 4,098,955 | +20,833 | $66.96M | $75.63M | 1.09% | +$8.66M |
| Arvinas, Inc.(ARVN) | 2,967,897 | 2,782,329 | -185,568 | $79.01M | $68.53M | 0.99% | -$10.48M |
| Stoke Therapeutics, Inc.(STOK) | 4,224,838 | 4,652,285 | +427,447 | $57.08M | $57.18M | 0.83% | +$99.0K |
| 89bio Inc | 7,378,548 | 7,378,548 | 0 | $59.10M | $54.60M | 0.79% | -$4.50M |
| CG Oncology, Inc.(CGON) | 1,344,074 | 1,344,074 | 0 | $42.43M | $50.71M | 0.73% | +$8.28M |
| Glaukos Corporation(GKOS) | 386,291 | 386,291 | 0 | $45.72M | $50.33M | 0.73% | +$4.61M |
| UroGen Pharma Ltd.(URGN) | 3,557,347 | 3,787,347 | +230,000 | $59.69M | $48.10M | 0.70% | -$11.59M |
| Neurogene Inc.(NGNE) | 1,070,565 | 1,135,256 | +64,691 | $38.96M | $47.64M | 0.69% | +$8.68M |
| Oruka Therapeutics, Inc.(ORKA) | 0 | 1,850,648 | +1,850,648 | $0 | $45.36M | 0.66% | +$45.36M |
| Orchestra BioMed Holdings, Inc.(OBIO) | 5,620,640 | 8,206,159 | +2,585,519 | $45.81M | $42.18M | 0.61% | -$3.63M |
| Sage Therapeutics Inc | 5,480,577 | 5,591,700 | +111,123 | $59.52M | $40.37M | 0.58% | -$19.15M |
| Taysha Gene Therapies, Inc.(TSHA) | 18,800,299 | 14,946,420 | -3,853,879 | $42.11M | $30.04M | 0.43% | -$12.07M |
| Cullinan Therapeutics, Inc.(CGEM) | 1,052,630 | 1,705,960 | +653,330 | $18.36M | $28.56M | 0.41% | +$10.20M |
| Tempus AI, Inc.CL A(TEM) | 400,000 | 400,000 | 0 | $14.00M | $22.64M | 0.33% | +$8.64M |
| GH Research PLC(GHRS) | 3,327,129 | 3,327,129 | 0 | $38.79M | $22.26M | 0.32% | -$16.54M |
| LENZ Therapeutics, Inc.(LENZ) | 863,389 | 863,389 | 0 | $14.93M | $20.50M | 0.30% | +$5.57M |
| Essa Pharma Inc | 2,298,662 | 3,261,496 | +962,834 | $12.09M | $19.76M | 0.29% | +$7.67M |
| Tourmaline Bio Inc | 741,656 | 741,656 | 0 | $9.54M | $19.07M | 0.28% | +$9.53M |
| Dianthus Therapeutics, Inc.(DNTH) | 666,667 | 666,667 | 0 | $17.25M | $18.25M | 0.26% | +$1.00M |
| Roivant Sciences Ltd.SHS(ROIV) | 1,454,273 | 1,454,273 | 0 | $15.37M | $16.78M | 0.24% | +$1.41M |
| BioAge Labs, Inc.(BIOA) | 0 | 786,353 | +786,353 | $0 | $16.36M | 0.24% | +$16.36M |
| Replimune Group, Inc.(REPL) | 1,133,787 | 1,133,787 | 0 | $10.20M | $12.43M | 0.18% | +$2.22M |
| Xencor, Inc.(XNCR) | 0 | 575,000 | +575,000 | $0 | $11.56M | 0.17% | +$11.56M |
| 10x Genomics, Inc.CL A(TXG) | 502,856 | 502,856 | 0 | $9.78M | $11.35M | 0.16% | +$1.57M |
| Immunic, Inc.(IMUX) | 4,567,717 | 4,567,717 | 0 | $5.07M | $7.54M | 0.11% | +$2.47M |
| Perceptive Cap Solutions CorCL A CL A ORD SHS | 742,500 | 742,500 | 0 | $7.47M | $7.43M | 0.11% | -$37.1K |
| Wave Life Sciences, Inc.SHS(WVE) | 0 | 900,000 | +900,000 | $0 | $7.38M | 0.11% | +$7.38M |
| IDEAYA Biosciences, Inc.(IDYA) | 0 | 200,000 | +200,000 | $0 | $6.34M | 0.09% | +$6.34M |
| Structure Therapeutics IncADS | 125,000 | 125,000 | 0 | $4.91M | $5.49M | 0.08% | +$577.5K |
| Milestone Pharmaceuticals Inc.(MIST) | 3,256,102 | 3,256,102 | 0 | $4.30M | $4.95M | 0.07% | +$651.2K |
| Acelyrin Inc | 978,310 | 978,310 | 0 | $4.31M | $4.82M | 0.07% | +$508.7K |
| Exagen Inc.(XGN) | 1,511,866 | 1,511,866 | 0 | $2.75M | $4.67M | 0.07% | +$1.92M |
| REGENXBIO Inc.(RGNX) | 350,000 | 350,000 | 0 | $4.09M | $3.67M | 0.05% | -$423.5K |
| Artiva Biotherapeutics, Inc.(ARTV) | 0 | 148,844 | +148,844 | $0 | $2.30M | 0.03% | +$2.30M |
| Allurion Technologies Inc | 3,697,549 | 3,697,549 | 0 | $3.69M | $2.27M | 0.03% | -$1.42M |
| SAB Biotherapeutics, Inc.(SABS) | 766,946 | 635,276 | -131,670 | $2.38M | $1.72M | 0.02% | -$662.3K |
| Centessa Pharmaceuticals PlcADS | 0 | 50,000 | +50,000 | $0 | $799.5K | 0.01% | +$799.5K |
| Adagio Medical Holdings, Inc.(ADGM) | 0 | 209,361 | +209,361 | $0 | $540.2K | 0.01% | +$540.2K |
| uniQure N.V.SHS(QURE) | 0 | 10,000 | +10,000 | $0 | $49.3K | 0.00% | +$49.3K |
| Rocket Pharmaceuticals, Inc.W EXP 09 02 202(RCKT) | 350,000 | 350,000 | 0 | $21.2K | $22.6K | 0.00% | +$1.3K |
| Adicet Bio Inc | 1,053,688 | 0 | -1,053,688 | $1.27M | $0 | — | -$1.27M |
| Arca Biopharma Inc | 1,400,000 | 0 | -1,400,000 | $5.36M | $0 | — | -$5.36M |
| Arya Sciences Acqu Corp IvCL A | 127,970 | 0 | -127,970 | $1.47M | $0 | — | -$1.47M |
| Cutera Inc | 1,331,776 | 0 | -1,331,776 | $2.01M | $0 | — | -$2.01M |
| CytomX Therapeutics, Inc.(CTMX) | 1,200,002 | 0 | -1,200,002 | $1.46M | $0 | — | -$1.46M |
| Fulcrum Therapeutics, Inc.(FULC) | 5,845,956 | 0 | -5,845,956 | $36.24M | $0 | — | -$36.24M |
| Intuitive Surgical, Inc.(ISRG) | 202,456 | 0 | -202,456 | $90.06M | $0 | — | -$90.06M |
| Kyverna Therapeutics, Inc.(KYTX) | 1,852,711 | 0 | -1,852,711 | $13.90M | $0 | — | -$13.90M |
| Sagimet Biosciences Inc.COM SER A(SGMT) | 500,000 | 0 | -500,000 | $1.71M | $0 | — | -$1.71M |
| Vericel Corporation(VCEL) | 801,397 | 0 | -801,397 | $36.77M | $0 | — | -$36.77M |
| Viridian Therapeutics, Inc.(VRDN) | 605,816 | 0 | -605,816 | $7.88M | $0 | — | -$7.88M |