Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q1 2026 ▲▼ | Q2 2026 ▲▼ | Change ▲▼ | Q1 2026 ▲▼ | Q2 2026 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| SPDR SERIES TRUST(Put) ST STR SP BIOT | 0 | 150,000 | +150,000 | 0 | 23,738 | — | +23,738 |
| BIOGEN INC(BIIB)(Call) | 0 | 100,000 | +100,000 | 0 | 21,606 | — | +21,606 |
| TEVA PHARMACEUTICAL INDS LTD(TEVA) | 1,136,975 | 1,500,082 | +363,107 | 34,246 | 50,823 | 6.63% | +16,577 |
| CYTOKINETICS INC(CYTK) | 0 | 219,987 | +219,987 | 0 | 18,741 | 2.44% | +18,741 |
| INSMED INC(INSM) | 0 | 118,800 | +118,800 | 0 | 12,666 | 1.65% | +12,666 |
| BIOMARIN PHARMACEUTICAL INC(BMRN) | 139,900 | 328,550 | +188,650 | 7,903 | 18,800 | 2.45% | +10,897 |
| RHYTHM PHARMACEUTICALS INC(RYTM) | 0 | 80,400 | +80,400 | 0 | 8,927 | 1.16% | +8,927 |
| LAM RESEARCH CORP(LRCX) | 0 | 18,470 | +18,470 | 0 | 8,004 | 1.04% | +8,004 |
| APPLIED MATLS INC | 0 | 11,040 | +11,040 | 0 | 7,982 | 1.04% | +7,982 |
| IDEAYA BIOSCIENCES INC(IDYA) | 0 | 196,408 | +196,408 | 0 | 7,320 | 0.95% | +7,320 |
| NUVECTIS PHARMA INC | 0 | 382,945 | +382,945 | 0 | 7,042 | 0.92% | +7,042 |
| HARMONY BIOSCIENCES HLDGS IN(HRMY) | 0 | 176,663 | +176,663 | 0 | 6,432 | 0.84% | +6,432 |
| CYBIN INC | 0 | 1,620,753 | +1,620,753 | 0 | 10,713 | 1.40% | +10,713 |
| MAZE THERAPEUTICS INC(MAZE) | 227,343 | 417,564 | +190,221 | 6,786 | 12,460 | 1.63% | +5,674 |
| SYNDAX PHARMACEUTICALS INC(SNDX) | 724,563 | 1,014,606 | +290,043 | 16,926 | 22,179 | 2.89% | +5,253 |
| VISTRA CORP(VST) | 0 | 29,450 | +29,450 | 0 | 4,672 | 0.61% | +4,672 |
| TALEN ENERGY CORP(TLN) | 0 | 12,135 | +12,135 | 0 | 4,663 | 0.61% | +4,663 |
| MADRIGAL PHARMACEUTICALS INC(MDGL) | 9,040 | 17,419 | +8,379 | 4,732 | 9,353 | 1.22% | +4,621 |
| GLOBAL X FDS CLOUD COMPUTNG | 0 | 195,900 | +195,900 | 0 | 4,455 | 0.58% | +4,455 |
| AVALO THERAPEUTICS INC(AVTX) | 0 | 232,294 | +232,294 | 0 | 4,293 | 0.56% | +4,293 |
| PRAXIS PRECISION MEDICINES I(PRAX)(Call) | 0 | 12,500 | +12,500 | 0 | 4,185 | — | +4,185 |
| CABALETTA BIO INC | 0 | 1,329,012 | +1,329,012 | 0 | 4,133 | 0.54% | +4,133 |
| BIOGEN INC(BIIB) | 92,526 | 96,626 | +4,100 | 16,963 | 20,877 | 2.72% | +3,914 |
| BIOAGE LABS INC | 86,518 | 213,671 | +127,153 | 1,513 | 5,237 | 0.68% | +3,724 |
| PRELUDE THERAPEUTICS INC | 558,339 | 1,019,832 | +461,493 | 1,910 | 5,436 | 0.71% | +3,526 |
| BRIDGEBIO ONCOLOGY THERAPEUT | 0 | 460,985 | +460,985 | 0 | 3,513 | 0.46% | +3,513 |
| CLIMB BIO INC | 419,247 | 483,747 | +64,500 | 2,872 | 6,308 | 0.82% | +3,436 |
| MINERALYS THERAPEUTICS INC(MLYS) | 1,339,971 | 1,469,971 | +130,000 | 36,300 | 39,660 | 5.17% | +3,360 |
| ACADIA PHARMACEUTICALS INC | 256,202 | 356,534 | +100,332 | 5,703 | 9,020 | 1.18% | +3,317 |
| PROQR THRAPEUTICS N V SHS EURO | 0 | 1,757,458 | +1,757,458 | 0 | 3,269 | 0.43% | +3,269 |
| ALNYLAM PHARMACEUTICALS INC(ALNY) | 0 | 10,800 | +10,800 | 0 | 3,251 | 0.42% | +3,251 |
| LARIMAR THERAPEUTICS INC | 0 | 926,004 | +926,004 | 0 | 2,824 | 0.37% | +2,824 |
| IMMIX BIOPHARMA INC | 0 | 270,000 | +270,000 | 0 | 2,784 | 0.36% | +2,784 |
| ULTRAGENYX PHARMACEUTICAL IN(RARE) | 809,333 | 588,494 | -220,839 | 16,956 | 19,650 | 2.56% | +2,694 |
| ABIVAX SA(ABVX)(Put) | 0 | 20,000 | +20,000 | 0 | 2,665 | — | +2,665 |
| TOWER SEMICONDUCTOR LTD(TSEM) | 145,735 | 108,265 | -37,470 | 25,574 | 28,218 | 3.68% | +2,645 |
| TREVI THERAPEUTICS INC(TRVI) | 574,029 | 499,029 | -75,000 | 6,848 | 9,307 | 1.21% | +2,459 |
| CONSTELLATION ENERGY CORP(CEG) | 0 | 9,850 | +9,850 | 0 | 2,446 | 0.32% | +2,446 |
| SATELLOS BIOSCIENCE INC | 489,207 | 652,590 | +163,383 | 2,754 | 5,074 | 0.66% | +2,320 |
| CYTOMX THERAPEUTICS INC. | 220,000 | 879,000 | +659,000 | 1,034 | 3,296 | 0.43% | +2,262 |
| NOVARTIS AG(NVS) | 37,000 | 50,000 | +13,000 | 5,652 | 7,833 | 1.02% | +2,181 |
| VOR BIOPHARMA INC(VOR) | 321,917 | 416,417 | +94,500 | 5,743 | 7,666 | 1.00% | +1,923 |
| TENAX THERAPEUTICS INC(Call) | 0 | 127,600 | +127,600 | 0 | 1,857 | — | +1,857 |
| GENERATE BIOMEDICINES INC(GENB) | 185,000 | 245,000 | +60,000 | 2,313 | 4,133 | 0.54% | +1,821 |
| COGENT BIOSCIENCES INC(COGT) | 416,340 | 459,340 | +43,000 | 16,025 | 17,776 | 2.32% | +1,752 |
| TAYSHA GENE THERAPIES INC(TSHA) | 0 | 250,000 | +250,000 | 0 | 1,703 | 0.22% | +1,703 |
| MERCK & CO INC(MRK) | 48,600 | 58,600 | +10,000 | 5,846 | 7,530 | 0.98% | +1,684 |
| PALISADE BIO INC | 1,733,471 | 2,257,106 | +523,635 | 3,034 | 4,717 | 0.62% | +1,684 |
| ZENAS BIOPHARMA INC(ZBIO) | 214,334 | 230,834 | +16,500 | 4,190 | 5,859 | 0.76% | +1,668 |
| PFIZER INC(PFE) | 186,000 | 286,000 | +100,000 | 5,223 | 6,887 | 0.90% | +1,664 |
| DYNE THERAPEUTICS INC(DYN) | 0 | 199,594 | +199,594 | 0 | 4,433 | 0.58% | +4,433 |
| NOVO-NORDISK A S(NVO) | 120,677 | 120,677 | 0 | 4,435 | 5,785 | 0.75% | +1,350 |
| ORIC PHARMACEUTICALS INC(ORIC) | 537,628 | 752,983 | +215,355 | 6,812 | 8,155 | 1.06% | +1,343 |
| ELI LILLY & CO(LLY) | 9,040 | 8,040 | -1,000 | 8,315 | 9,643 | 1.26% | +1,329 |
| INHIBIKASE THERAPEUTICS INC | 0 | 649,309 | +649,309 | 0 | 1,318 | 0.17% | +1,318 |
| CELLDEX THERAPEUTICS INC NEW(CLDX) | 243,575 | 240,868 | -2,707 | 7,726 | 8,963 | 1.17% | +1,236 |
| DISC MEDICINE INC(IRON) | 53,538 | 63,538 | +10,000 | 3,423 | 4,647 | 0.61% | +1,224 |
| ORIC PHARMACEUTICALS INC(ORIC)(Call) | 0 | 100,000 | +100,000 | 0 | 1,083 | — | +1,083 |
| ABBVIE INC(ABBV) | 30,256 | 30,256 | 0 | 6,580 | 7,614 | 0.99% | +1,033 |
| SOLAREDGE TECHNOLOGIES INC(SEDG) | 4,000,000 | 4,000,000 | 0 | 6,910 | 7,747 | 1.01% | +838 |
| KURA ONCOLOGY INC(KURA) | 295,522 | 295,039 | -483 | 2,403 | 3,237 | 0.42% | +834 |
| ALPHA COGNITION INC | 567,616 | 545,816 | -21,800 | 3,116 | 3,941 | 0.51% | +825 |
| TANGO THERAPEUTICS INC(TNGX) | 343,563 | 254,250 | -89,313 | 7,187 | 7,948 | 1.04% | +761 |
| CONTINEUM THERAPEUTICS INC | 173,475 | 183,475 | +10,000 | 2,266 | 3,007 | 0.39% | +742 |
| SAVARA INC(SVRA) | 0 | 756,164 | +756,164 | 0 | 4,658 | 0.61% | +4,658 |
| VERASTEM INC | 343,678 | 632,632 | +288,954 | 1,821 | 2,417 | 0.32% | +595 |
| FIRST TRACKS BIOTHERAPEUTICS | 0 | 27,876 | +27,876 | 0 | 561 | 0.07% | +561 |
| SCHOLAR ROCK HLDG CORP(SRRK) | 0 | 94,265 | +94,265 | 0 | 5,185 | 0.68% | +5,185 |
| FORTE BIOSCIENCES INC(FBRX) | 184,984 | 249,693 | +64,709 | 4,791 | 5,306 | 0.69% | +515 |
| IMMATICS N.V(IMTX) | 0 | 720,057 | +720,057 | 0 | 7,294 | 0.95% | +7,294 |
| TRAWS PHARMA INC | 0 | 398,486 | +398,486 | 0 | 336 | 0.04% | +336 |
| RELAY THERAPEUTICS INC(RLAY) | 408,436 | 233,836 | -174,600 | 4,064 | 4,375 | 0.57% | +311 |
| JOHNSON & JOHNSON(JNJ) | 28,831 | 28,831 | 0 | 7,047 | 7,322 | 0.96% | +275 |
| PROMIS NEUROSCIENCES INC | 325,591 | 325,591 | 0 | 4,135 | 4,285 | 0.56% | +150 |
| AMGEN INC(AMGN) | 7,500 | 7,500 | 0 | 2,639 | 2,716 | 0.35% | +77 |
| BRIDGEBIO PHARMA INC(BBIO) | 245,246 | 245,346 | +100 | 18,212 | 18,273 | 2.38% | +61 |
| SKYE BIOSCIENCE INC | 678,928 | 678,928 | 0 | 417 | 471 | 0.06% | +53 |
| OVID THERAPEUTICS INC | 1,622,828 | 1,353,000 | -269,828 | 3,603 | 3,640 | 0.47% | +37 |
| ORGANOGENESIS HLDGS INC | 550,000 | 550,000 | 0 | 1,304 | 1,337 | 0.17% | +33 |
| CORVUS PHARMACEUTICALS INC(CRVS) | 247,961 | 244,961 | -3,000 | 3,628 | 3,660 | 0.48% | +32 |
| APREA THERAPEUTICS INC | 270,000 | 270,000 | 0 | 206 | 217 | 0.03% | +11 |
| ISHARES TR(Call) | 47,000 | 47,000 | 0 | 4,074 | 4,062 | — | -13 |
| CURIS INC | 1,994,937 | 98,996 | -1,895,941 | 1,092 | 1,034 | 0.13% | -58 |
| FOGHORN THERAPEUTICS INC | 12,224 | 0 | -12,224 | 58 | 0 | — | -58 |
| PRECISION BIOSCIENCES INC | 40,000 | 0 | -40,000 | 220 | 0 | — | -220 |
| WAVE LIFE SCIENCES LTD(WVE) | 0 | 638,272 | +638,272 | 0 | 3,708 | 0.48% | +3,708 |
| ENLIVEN THERAPEUTICS INC | 153,265 | 112,765 | -40,500 | 6,008 | 5,723 | 0.75% | -285 |
| WEREWOLF THERAPEUTICS INC | 626,810 | 626,810 | 0 | 522 | 226 | 0.03% | -296 |
| VOYAGER THERAPEUTICS INC | 469,761 | 427,554 | -42,207 | 1,813 | 1,496 | 0.20% | -317 |
| MEDIWOUND LTD | 273,192 | 273,192 | 0 | 4,401 | 4,016 | 0.52% | -385 |
| TENAX THERAPEUTICS INC | 136,015 | 120,200 | -15,815 | 2,175 | 1,749 | 0.23% | -426 |
| ASTRAZENECA PLC(AZN) | 62,530 | 62,530 | 0 | 12,332 | 11,857 | 1.55% | -475 |
| NICE LTD(NICE) | 5,611 | 0 | -5,611 | 619 | 0 | — | -619 |
| ELEDON PHARMACEUTICALS INC | 1,772,131 | 1,191,187 | -580,944 | 5,458 | 4,693 | 0.61% | -765 |
| STRUCTURE THERAPEUTICS INC | 50,800 | 28,600 | -22,200 | 2,449 | 1,535 | 0.20% | -914 |
| XENON PHARMACEUTICALS INC(XENE) | 127,000 | 105,000 | -22,000 | 7,385 | 6,338 | 0.83% | -1,047 |
| BRISTOL-MYERS SQUIBB CO(BMY) | 17,500 | 0 | -17,500 | 1,061 | 0 | — | -1,061 |
| REVOLUTION MEDICINES INC(RVMD) | 55,110 | 22,400 | -32,710 | 5,359 | 4,195 | 0.55% | -1,164 |
| KODIAK SCIENCES INC(KOD) | 114,796 | 81,796 | -33,000 | 4,376 | 3,187 | 0.42% | -1,189 |
| SHATTUCK LABS INC | 280,786 | 86,461 | -194,325 | 1,805 | 600 | 0.08% | -1,205 |