Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q4 2024 ▲▼ | Q1 2025 ▲▼ | Change ▲▼ | Q4 2024 ▲▼ | Q1 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| HOME DEPOT INC(HD) | 0 | 97,571 | +97,571 | 0 | 35,759 | 1.45% | +35,759 |
| BANK AMERICA CORP | 0 | 753,913 | +753,913 | 0 | 31,461 | 1.27% | +31,461 |
| CHIPOTLE MEXICAN GRILL INC(CMG) | 0 | 539,540 | +539,540 | 0 | 27,090 | 1.10% | +27,090 |
| MINERALYS THERAPEUTICS INC(MLYS) | 0 | 1,667,759 | +1,667,759 | 0 | 26,484 | 1.07% | +26,484 |
| ULTRAGENYX PHARMACEUTICAL IN(RARE) | 1,151,314 | 2,024,500 | +873,186 | 48,436 | 73,307 | 2.97% | +24,871 |
| 89BIO INC | 10,202,696 | 14,335,244 | +4,132,548 | 79,785 | 104,217 | 4.22% | +24,432 |
| SNOWFLAKE INC(SNOW) | 0 | 137,886 | +137,886 | 0 | 20,153 | 0.82% | +20,153 |
| ARCUTIS BIOTHERAPEUTICS INC(ARQT) | 11,399,138 | 11,422,978 | +23,840 | 158,790 | 178,655 | 7.23% | +19,865 |
| MICROSOFT CORP(MSFT) | 118,397 | 180,125 | +61,728 | 49,904 | 67,617 | 2.74% | +17,713 |
| AURA BIOSCIENCES INC(AURA) | 0 | 2,731,886 | +2,731,886 | 0 | 16,009 | 0.65% | +16,009 |
| BENITEC BIOPHARMA INC(BNTC) | 8,960,009 | 9,876,506 | +916,497 | 113,165 | 128,493 | 5.20% | +15,328 |
| KALVISTA PHARMACEUTICALS INC | 4,913,012 | 4,913,012 | 0 | 41,613 | 56,696 | 2.29% | +15,083 |
| TAKE-TWO INTERACTIVE SOFTWAR(TTWO) | 0 | 72,400 | +72,400 | 0 | 15,005 | 0.61% | +15,005 |
| MODERNA INC(MRNA) | 0 | 517,163 | +517,163 | 0 | 14,662 | 0.59% | +14,662 |
| NVIDIA CORPORATION(NVDA) | 180,756 | 352,765 | +172,009 | 24,274 | 38,233 | 1.55% | +13,959 |
| LEGEND BIOTECH CORP(LEGN) | 3,496,234 | 3,749,965 | +253,731 | 113,767 | 127,236 | 5.15% | +13,469 |
| ROBLOX CORP(RBLX) | 0 | 227,710 | +227,710 | 0 | 13,273 | 0.54% | +13,273 |
| ARCUS BIOSCIENCES INC(RCUS) | 576,156 | 2,560,904 | +1,984,748 | 8,579 | 20,103 | 0.81% | +11,524 |
| PALVELLA THERAPEUTICS INC NE(PVLA) | 714,463 | 714,463 | 0 | 8,574 | 19,998 | 0.81% | +11,424 |
| APELLIS PHARMACEUTICALS INC COM | 793,187 | 1,646,615 | +853,428 | 25,311 | 36,011 | 1.46% | +10,701 |
| MERCK & CO INC(MRK) | 53,000 | 144,100 | +91,100 | 5,272 | 12,934 | 0.52% | +7,662 |
| GE AEROSPACE(GE) | 200,662 | 200,662 | 0 | 33,468 | 40,162 | 1.63% | +6,694 |
| UNITY SOFTWARE INC(U) | 0 | 339,560 | +339,560 | 0 | 6,652 | 0.27% | +6,652 |
| WHITEHAWK THERAPEUTICS INC(WHWK) | 0 | 3,700,000 | +3,700,000 | 0 | 6,586 | 0.27% | +6,586 |
| UNITED AIRLS HLDGS INC(UAL) | 200,650 | 366,375 | +165,725 | 19,483 | 25,298 | 1.02% | +5,815 |
| IMMATICS N.V(IMTX) | 5,065,277 | 9,135,029 | +4,069,752 | 36,014 | 41,199 | 1.67% | +5,185 |
| KURA ONCOLOGY INC(KURA) | 5,076,448 | 7,439,259 | +2,362,811 | 44,216 | 49,099 | 1.99% | +4,883 |
| ABBOTT LABS | 33,520 | 58,820 | +25,300 | 3,791 | 7,802 | 0.32% | +4,011 |
| DISC MEDICINE INC(IRON) | 0 | 80,000 | +80,000 | 0 | 3,971 | 0.16% | +3,971 |
| META PLATFORMS INC(META) | 170,338 | 179,664 | +9,326 | 99,735 | 103,551 | 4.19% | +3,817 |
| INSMED INC(INSM) | 1,611,561 | 1,492,383 | -119,178 | 111,262 | 113,854 | 4.61% | +2,592 |
| ALNYLAM PHARMACEUTICALS INC(ALNY) | 0 | 9,370 | +9,370 | 0 | 2,530 | 0.10% | +2,530 |
| AARDVARK THERAPEUTICS INC | 0 | 312,500 | +312,500 | 0 | 2,347 | 0.09% | +2,347 |
| TREVI THERAPEUTICS INC(TRVI) | 0 | 340,164 | +340,164 | 0 | 2,140 | 0.09% | +2,140 |
| ORIC PHARMACEUTICALS INC(ORIC) | 0 | 255,000 | +255,000 | 0 | 1,423 | 0.06% | +1,423 |
| MEDTRONIC PLC(MDT) | 17,460 | 25,060 | +7,600 | 1,395 | 2,252 | 0.09% | +857 |
| ADVANCED MICRO DEVICES INC(AMD) | 337,415 | 404,008 | +66,593 | 40,756 | 41,508 | 1.68% | +751 |
| CENCORA INC | 12,488 | 12,488 | 0 | 2,806 | 3,473 | 0.14% | +667 |
| STRYKER CORPORATION(SYK) | 4,360 | 5,860 | +1,500 | 1,570 | 2,181 | 0.09% | +612 |
| MCKESSON CORP(MCK) | 1,830 | 1,830 | 0 | 1,043 | 1,232 | 0.05% | +189 |
| ELEVANCE HEALTH INC(ELV) | 2,740 | 2,740 | 0 | 1,011 | 1,192 | 0.05% | +181 |
| HCA HEALTHCARE INC(HCA) | 3,190 | 3,190 | 0 | 957 | 1,102 | 0.04% | +145 |
| BAXTER INTL INC | 7,970 | 7,970 | 0 | 232 | 273 | 0.01% | +40 |
| STERIS PLC(STE) | 1,530 | 1,530 | 0 | 315 | 347 | 0.01% | +32 |
| ZIMMER BIOMET HOLDINGS INC(ZBH) | 3,260 | 3,260 | 0 | 344 | 369 | 0.01% | +25 |
| WATERS CORP(WAT) | 3,150 | 3,150 | 0 | 1,169 | 1,161 | 0.05% | -8 |
| RESMED INC(RMD) | 2,390 | 2,390 | 0 | 547 | 535 | 0.02% | -12 |
| EDWARDS LIFESCIENCES CORP | 11,100 | 11,100 | 0 | 822 | 805 | 0.03% | -17 |
| VERALTO CORP(VLTO) | 5,475 | 5,475 | 0 | 558 | 534 | 0.02% | -24 |
| PACS GROUP INC(PACS) | 20,000 | 20,000 | 0 | 262 | 225 | 0.01% | -37 |
| IONIS PHARMACEUTICALS INC(IONS) | 10,800 | 10,800 | 0 | 378 | 326 | 0.01% | -52 |
| METTLER TOLEDO INTERNATIONAL(MTD) | 1,964 | 1,964 | 0 | 2,403 | 2,319 | 0.09% | -84 |
| AGILENT TECHNOLOGIES INC(A) | 4,990 | 4,990 | 0 | 670 | 584 | 0.02% | -87 |
| GALAPAGOS NV(LKFT) | 37,111 | 37,111 | 0 | 1,021 | 932 | 0.04% | -88 |
| INTUITIVE SURGICAL INC | 5,200 | 5,200 | 0 | 2,714 | 2,575 | 0.10% | -139 |
| IQVIA HLDGS INC(IQV) | 7,175 | 7,175 | 0 | 1,410 | 1,265 | 0.05% | -145 |
| NATERA INC(NTRA) | 10,100 | 10,100 | 0 | 1,599 | 1,428 | 0.06% | -171 |
| THERMO FISHER SCIENTIFIC INC(TMO) | 7,900 | 7,900 | 0 | 4,110 | 3,931 | 0.16% | -179 |
| ALIGN TECHNOLOGY INC | 1,100 | 0 | -1,100 | 229 | 0 | — | -229 |
| DEXCOM INC(DXCM) | 31,680 | 31,680 | 0 | 2,464 | 2,163 | 0.09% | -300 |
| DANAHER CORPORATION(DHR) | 13,600 | 13,600 | 0 | 3,122 | 2,788 | 0.11% | -334 |
| AVANTOR INC(AVTR) | 71,850 | 71,850 | 0 | 1,514 | 1,165 | 0.05% | -349 |
| ELANCO ANIMAL HEALTH INC(ELAN) | 253,600 | 253,600 | 0 | 3,071 | 2,663 | 0.11% | -408 |
| CAPITAL ONE FINL CORP(COF) | 251,642 | 245,222 | -6,420 | 44,873 | 43,968 | 1.78% | -904 |
| SAREPTA THERAPEUTICS INC(SRPT) | 17,888 | 17,888 | 0 | 2,175 | 1,142 | 0.05% | -1,033 |
| FULCRUM THERAPEUTICS INC(FULC) | 3,338,466 | 5,067,394 | +1,728,928 | 15,691 | 14,594 | 0.59% | -1,097 |
| BIOGEN INC(BIIB) | 115,436 | 120,736 | +5,300 | 17,652 | 16,522 | 0.67% | -1,131 |
| EXACT SCIENCES CORP(EXK) | 94,100 | 94,100 | 0 | 5,287 | 4,074 | 0.16% | -1,214 |
| KEZAR LIFE SCIENCES INC COM NEW | 716,759 | 716,759 | 0 | 4,817 | 3,498 | 0.14% | -1,319 |
| SANOFI(SNY) | 131,501 | 83,701 | -47,800 | 6,342 | 4,642 | 0.19% | -1,700 |
| BRISTOL-MYERS SQUIBB CO(BMY) | 33,800 | 0 | -33,800 | 1,912 | 0 | — | -1,912 |
| MOLECULAR PARTNERS AG(MOLN) | 2,221,494 | 2,221,494 | 0 | 10,548 | 8,620 | 0.35% | -1,928 |
| JOHNSON & JOHNSON(JNJ) | 139,986 | 109,386 | -30,600 | 20,245 | 18,141 | 0.73% | -2,104 |
| PEPGEN INC(PEPG) | 1,174,321 | 1,660,932 | +486,611 | 4,451 | 2,334 | 0.09% | -2,117 |
| BIOAGE LABS INC(BIOA) | 1,452,336 | 1,452,336 | 0 | 8,409 | 5,461 | 0.22% | -2,948 |
| ABEONA THERAPEUTICS INC(ABEO) | 3,685,503 | 3,685,503 | 0 | 20,528 | 17,543 | 0.71% | -2,985 |
| MONTE ROSA THERAPEUTICS INC(GLUE) | 1,563,798 | 1,563,798 | 0 | 10,853 | 7,256 | 0.29% | -3,597 |
| GE HEALTHCARE TECHNOLOGIES I(GEHC) | 75,000 | 0 | -75,000 | 5,864 | 0 | — | -5,863 |
| ZURA BIO LTD(ZURA) | 4,860,939 | 4,860,939 | 0 | 12,152 | 6,271 | 0.25% | -5,882 |
| ORACLE CORP(ORCL) | 226,318 | 226,318 | 0 | 37,714 | 31,642 | 1.28% | -6,072 |
| SCPHARMACEUTICALS INC | 1,840,891 | 0 | -1,840,891 | 6,517 | 0 | — | -6,517 |
| DATADOG INC(DDOG) | 176,450 | 183,231 | +6,781 | 25,213 | 18,178 | 0.74% | -7,035 |
| INFLARX NV(IFRX) | 5,733,910 | 6,483,910 | +750,000 | 14,163 | 6,614 | 0.27% | -7,549 |
| SUTRO BIOPHARMA INC(STRO) | 7,462,495 | 7,462,495 | 0 | 13,731 | 4,855 | 0.20% | -8,876 |
| ROCKET PHARMACEUTICALS INC(RCKT) | 2,566,951 | 3,502,000 | +935,049 | 32,267 | 23,358 | 0.95% | -8,908 |
| BOSTON SCIENTIFIC CORP(BSX) | 397,679 | 262,099 | -135,580 | 35,521 | 26,441 | 1.07% | -9,080 |
| CAESARS ENTERTAINMENT INC NE(CZR) | 772,412 | 652,493 | -119,919 | 25,814 | 16,312 | 0.66% | -9,502 |
| AMAZON COM INC(AMZN) | 351,281 | 354,356 | +3,075 | 77,068 | 67,420 | 2.73% | -9,648 |
| PROKIDNEY CORP(PROK) | 12,341,266 | 12,341,266 | 0 | 20,857 | 10,813 | 0.44% | -10,043 |
| TAIWAN SEMICONDUCTOR MFG LTD(TSM) | 345,912 | 350,514 | +4,602 | 68,314 | 58,185 | 2.35% | -10,129 |
| DISNEY WALT CO(DIS) | 94,580 | 0 | -94,580 | 10,531 | 0 | — | -10,531 |
| CROWDSTRIKE HLDGS INC(CRWD) | 36,093 | 0 | -36,093 | 12,350 | 0 | — | -12,350 |
| CONTINEUM THERAPEUTICS INC(CTNM) | 1,720,000 | 1,720,000 | 0 | 25,198 | 12,006 | 0.49% | -13,192 |
| EYEPOINT PHARMACEUTICALS INC(EYPT) | 6,783,091 | 6,804,091 | +21,000 | 50,534 | 36,878 | 1.49% | -13,656 |
| ERASCA INC(ERAS) | 12,315,004 | 12,315,004 | 0 | 30,911 | 16,872 | 0.68% | -14,039 |
| DOMINOS PIZZA INC(DPZ) | 38,340 | 0 | -38,340 | 16,094 | 0 | — | -16,094 |
| ARRIVENT BIOPHARMA INC(AVBP) | 2,246,000 | 2,337,496 | +91,496 | 59,833 | 43,220 | 1.75% | -16,613 |
| FERGUSON ENTERPRISES INC(FERG) | 245,530 | 129,924 | -115,606 | 42,617 | 20,818 | 0.84% | -21,799 |
| APOLLO GLOBAL MGMT INC(APO) | 464,140 | 396,540 | -67,600 | 76,657 | 54,302 | 2.20% | -22,355 |
| UNITEDHEALTH GROUP INC(UNH) | 75,198 | 29,900 | -45,298 | 38,040 | 15,660 | 0.63% | -22,380 |