Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q2 2025 ▲▼ | Q3 2025 ▲▼ | Change ▲▼ | Q2 2025 ▲▼ | Q3 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| MINERALYS THERAPEUTICS INC(MLYS) | 1,744,492 | 2,132,133 | +387,641 | 23,603 | 80,850 | 2.45% | +57,248 |
| KEURIG DR PEPPER INC(KDP) | 0 | 1,570,000 | +1,570,000 | 0 | 40,051 | 1.21% | +40,051 |
| IMMATICS N.V(IMTX) | 12,030,129 | 12,030,129 | 0 | 64,722 | 102,497 | 3.11% | +37,775 |
| ARCUTIS BIOTHERAPEUTICS INC(ARQT) | 11,535,582 | 10,478,000 | -1,057,582 | 161,729 | 197,510 | 5.99% | +35,781 |
| PALVELLA THERAPEUTICS INC NE(PVLA) | 714,463 | 822,400 | +107,937 | 16,104 | 51,556 | 1.56% | +35,452 |
| ADVISORSHARES TR PURE US CANN ETF | 0 | 7,167,000 | +7,167,000 | 0 | 34,330 | 1.04% | +34,330 |
| AVIDITY BIOSCIENCES INC | 0 | 750,000 | +750,000 | 0 | 32,678 | 0.99% | +32,678 |
| HOME DEPOT INC(HD) | 130,721 | 197,311 | +66,590 | 47,928 | 79,948 | 2.42% | +32,021 |
| COMPASS THERAPEUTICS INC(CMPX) | 7,149,493 | 14,101,159 | +6,951,666 | 18,589 | 49,354 | 1.50% | +30,765 |
| PROKIDNEY CORP(PROK) | 0 | 12,341,266 | +12,341,266 | 0 | 29,866 | 0.91% | +29,866 |
| SALESFORCE INC(CRM) | 0 | 125,250 | +125,250 | 0 | 29,684 | 0.90% | +29,684 |
| FERGUSON ENTERPRISES INC(FERG) | 189,660 | 306,260 | +116,600 | 41,298 | 68,780 | 2.09% | +27,481 |
| KURA ONCOLOGY INC(KURA) | 8,116,000 | 8,116,000 | 0 | 46,829 | 71,827 | 2.18% | +24,997 |
| EYEPOINT PHARMACEUTICALS INC(EYPT) | 6,804,091 | 6,192,715 | -611,376 | 64,026 | 88,184 | 2.67% | +24,158 |
| BENITEC BIOPHARMA INC(BNTC) | 9,876,506 | 9,876,506 | 0 | 115,555 | 138,567 | 4.20% | +23,012 |
| MARVELL TECHNOLOGY INC(MRVL) | 0 | 272,300 | +272,300 | 0 | 22,892 | 0.69% | +22,892 |
| SERVICENOW INC(NOW) | 0 | 22,000 | +22,000 | 0 | 20,246 | 0.61% | +20,246 |
| ARCUS BIOSCIENCES INC(RCUS) | 3,688,858 | 3,688,858 | 0 | 30,027 | 50,168 | 1.52% | +20,141 |
| SNOWFLAKE INC(SNOW) | 0 | 89,200 | +89,200 | 0 | 20,119 | 0.61% | +20,119 |
| ZURA BIO LTD(ZURA) | 4,860,939 | 5,472,891 | +611,952 | 5,104 | 23,698 | 0.72% | +18,594 |
| DANAHER CORPORATION(DHR) | 174,700 | 255,800 | +81,100 | 34,510 | 50,715 | 1.54% | +16,205 |
| BANK AMERICA CORP | 927,190 | 1,160,330 | +233,140 | 43,875 | 59,861 | 1.81% | +15,987 |
| APELLIS PHARMACEUTICALS INC COM | 2,878,000 | 2,878,000 | 0 | 49,818 | 65,129 | 1.97% | +15,311 |
| FULCRUM THERAPEUTICS INC(FULC) | 5,082,900 | 5,381,000 | +298,100 | 34,970 | 49,505 | 1.50% | +14,535 |
| GE AEROSPACE(GE) | 310,262 | 310,262 | 0 | 79,858 | 93,333 | 2.83% | +13,475 |
| CONTINEUM THERAPEUTICS INC(CTNM) | 1,720,000 | 1,720,000 | 0 | 6,828 | 20,210 | 0.61% | +13,382 |
| ORACLE CORP(ORCL) | 230,728 | 226,318 | -4,410 | 50,444 | 63,650 | 1.93% | +13,206 |
| ERASCA INC(ERAS) | 14,502,004 | 14,502,004 | 0 | 18,418 | 31,614 | 0.96% | +13,197 |
| UNITEDHEALTH GROUP INC(UNH) | 68,000 | 96,220 | +28,220 | 21,214 | 33,225 | 1.01% | +12,011 |
| NVIDIA CORPORATION(NVDA) | 499,562 | 483,535 | -16,027 | 78,926 | 90,218 | 2.74% | +11,292 |
| TESLA INC(TSLA) | 92,357 | 91,252 | -1,105 | 29,338 | 40,582 | 1.23% | +11,243 |
| MONTE ROSA THERAPEUTICS INC(GLUE) | 3,360,000 | 3,360,000 | 0 | 15,154 | 24,898 | 0.75% | +9,744 |
| CAPITAL ONE FINL CORP(COF) | 194,160 | 238,770 | +44,610 | 41,309 | 50,758 | 1.54% | +9,448 |
| TAIWAN SEMICONDUCTOR MFG LTD(TSM) | 300,401 | 277,201 | -23,200 | 68,038 | 77,419 | 2.35% | +9,382 |
| COCA COLA CO(KO) | 1,233,230 | 1,455,080 | +221,850 | 87,251 | 96,501 | 2.93% | +9,250 |
| ADVANCED MICRO DEVICES INC(AMD) | 398,799 | 398,799 | 0 | 56,590 | 64,522 | 1.96% | +7,932 |
| MICROSOFT CORP(MSFT) | 98,828 | 109,455 | +10,627 | 49,158 | 56,692 | 1.72% | +7,534 |
| INSMED INC(INSM) | 238,783 | 217,783 | -21,000 | 24,031 | 31,363 | 0.95% | +7,332 |
| REGENERON PHARMACEUTICALS(REGN) | 8,630 | 17,730 | +9,100 | 4,531 | 9,969 | 0.30% | +5,438 |
| BIOHAVEN LTD(BHVN) | 5,620,271 | 5,620,271 | 0 | 79,302 | 84,360 | 2.56% | +5,058 |
| BIOGEN INC(BIIB) | 151,890 | 168,190 | +16,300 | 19,076 | 23,560 | 0.71% | +4,484 |
| JOHNSON & JOHNSON(JNJ) | 132,786 | 132,786 | 0 | 20,283 | 24,621 | 0.75% | +4,338 |
| INFLARX NV(IFRX) | 6,483,910 | 6,483,910 | 0 | 5,122 | 8,688 | 0.26% | +3,566 |
| THERMO FISHER SCIENTIFIC INC(TMO) | 7,900 | 13,400 | +5,500 | 3,203 | 6,499 | 0.20% | +3,296 |
| UNITED THERAPEUTICS CORP DEL(UTHR) | 0 | 7,500 | +7,500 | 0 | 3,144 | 0.10% | +3,144 |
| ROCKET PHARMACEUTICALS INC(RCKT) | 4,143,333 | 3,843,333 | -300,000 | 10,151 | 12,529 | 0.38% | +2,378 |
| GOLDMAN SACHS GROUP INC(GS) | 24,108 | 24,108 | 0 | 17,062 | 19,198 | 0.58% | +2,136 |
| KALVISTA PHARMACEUTICALS INC | 4,955,000 | 4,768,712 | -186,288 | 56,016 | 58,083 | 1.76% | +2,067 |
| ELANCO ANIMAL HEALTH INC(ELAN) | 253,600 | 253,600 | 0 | 3,621 | 5,108 | 0.15% | +1,486 |
| ABBOTT LABS | 40,520 | 51,020 | +10,500 | 5,511 | 6,834 | 0.21% | +1,322 |
| MERCK & CO INC(MRK) | 219,178 | 219,178 | 0 | 17,350 | 18,396 | 0.56% | +1,045 |
| SUTRO BIOPHARMA INC(STRO) | 6,488,324 | 6,488,324 | 0 | 4,632 | 5,634 | 0.17% | +1,002 |
| PINTEREST INC(PINS) | 430,025 | 497,185 | +67,160 | 15,421 | 15,994 | 0.48% | +574 |
| IONIS PHARMACEUTICALS INC(IONS) | 10,800 | 10,800 | 0 | 427 | 707 | 0.02% | +280 |
| GALAPAGOS NV(LKFT) | 37,111 | 37,111 | 0 | 1,039 | 1,286 | 0.04% | +247 |
| IQVIA HLDGS INC(IQV) | 7,175 | 7,175 | 0 | 1,131 | 1,363 | 0.04% | +232 |
| MEDTRONIC PLC(MDT) | 25,060 | 25,060 | 0 | 2,184 | 2,387 | 0.07% | +202 |
| META PLATFORMS INC(META) | 169,845 | 170,973 | +1,128 | 125,361 | 125,559 | 3.81% | +198 |
| CENCORA INC | 12,488 | 12,488 | 0 | 3,745 | 3,903 | 0.12% | +158 |
| EXACT SCIENCES CORP(EXK) | 94,100 | 94,100 | 0 | 5,000 | 5,148 | 0.16% | +148 |
| HCA HEALTHCARE INC(HCA) | 3,190 | 3,190 | 0 | 1,222 | 1,360 | 0.04% | +137 |
| WHITEHAWK THERAPEUTICS INC(WHWK) | 3,700,000 | 3,700,000 | 0 | 6,919 | 7,030 | 0.21% | +111 |
| METTLER TOLEDO INTERNATIONAL(MTD) | 1,964 | 1,964 | 0 | 2,307 | 2,411 | 0.07% | +104 |
| MCKESSON CORP(MCK) | 1,830 | 1,830 | 0 | 1,341 | 1,414 | 0.04% | +73 |
| AGILENT TECHNOLOGIES INC(A) | 4,990 | 4,990 | 0 | 589 | 640 | 0.02% | +52 |
| SAREPTA THERAPEUTICS INC(SRPT) | 17,888 | 17,888 | 0 | 306 | 345 | 0.01% | +39 |
| RESMED INC(RMD) | 2,390 | 2,390 | 0 | 617 | 654 | 0.02% | +38 |
| VERALTO CORP(VLTO) | 5,475 | 5,475 | 0 | 553 | 584 | 0.02% | +31 |
| ZIMMER BIOMET HOLDINGS INC(ZBH) | 3,260 | 3,260 | 0 | 297 | 321 | 0.01% | +24 |
| PACS GROUP INC(PACS) | 20,000 | 20,000 | 0 | 258 | 275 | 0.01% | +16 |
| STERIS PLC(STE) | 1,530 | 1,530 | 0 | 368 | 379 | 0.01% | +11 |
| EDWARDS LIFESCIENCES CORP | 11,100 | 11,100 | 0 | 868 | 863 | 0.03% | -5 |
| AVANTOR INC(AVTR) | 71,850 | 71,850 | 0 | 967 | 897 | 0.03% | -70 |
| NATERA INC(NTRA) | 10,100 | 10,100 | 0 | 1,706 | 1,626 | 0.05% | -80 |
| STRYKER CORPORATION(SYK) | 5,860 | 5,860 | 0 | 2,318 | 2,166 | 0.07% | -152 |
| WATERS CORP(WAT) | 3,150 | 3,150 | 0 | 1,099 | 944 | 0.03% | -155 |
| ALIGN TECHNOLOGY INC | 1,100 | 0 | -1,100 | 208 | 0 | — | -208 |
| BAXTER INTL INC | 7,970 | 0 | -7,970 | 241 | 0 | — | -241 |
| MOLECULAR PARTNERS AG(MOLN) | 2,221,494 | 2,221,494 | 0 | 8,486 | 8,242 | 0.25% | -244 |
| PEPGEN INC(PEPG) | 300,000 | 0 | -300,000 | 333 | 0 | — | -333 |
| AURA BIOSCIENCES INC(AURA) | 4,372,884 | 4,372,884 | 0 | 27,374 | 27,024 | 0.82% | -350 |
| KEZAR LIFE SCIENCES INC COM NEW | 716,759 | 716,759 | 0 | 3,283 | 2,795 | 0.08% | -487 |
| INTUITIVE SURGICAL INC | 5,200 | 5,200 | 0 | 2,826 | 2,326 | 0.07% | -500 |
| CAESARS ENTERTAINMENT INC NE(CZR) | 18,875 | 0 | -18,875 | 536 | 0 | — | -536 |
| DEXCOM INC(DXCM) | 31,680 | 31,680 | 0 | 2,765 | 2,132 | 0.06% | -634 |
| CRH PLC ORD | 8,460 | 0 | -8,460 | 777 | 0 | — | -777 |
| UNITED AIRLS HLDGS INC(UAL) | 10,401 | 0 | -10,401 | 828 | 0 | — | -828 |
| ONESTREAM INC CL A | 33,080 | 0 | -33,080 | 936 | 0 | — | -936 |
| ABEONA THERAPEUTICS INC(ABEO) | 2,676,000 | 2,676,000 | 0 | 15,200 | 14,129 | 0.43% | -1,070 |
| WINGSTOP INC(WING) | 3,961 | 0 | -3,961 | 1,334 | 0 | — | -1,334 |
| APOLLO GLOBAL MGMT INC(APO) | 428,460 | 431,260 | +2,800 | 60,786 | 57,474 | 1.74% | -3,312 |
| BOSTON SCIENTIFIC CORP(BSX) | 353,561 | 353,561 | 0 | 37,976 | 34,518 | 1.05% | -3,458 |
| ARRIVENT BIOPHARMA INC(AVBP) | 3,412,788 | 3,703,452 | +290,664 | 74,296 | 68,329 | 2.07% | -5,968 |
| PROKIDNEY CORP(PROK) | 12,341,266 | 0 | -12,341,266 | 7,307 | 0 | — | -7,307 |
| TAYSHA GENE THERAPIES INC(TSHA) | 3,217,449 | 0 | -3,217,449 | 7,432 | 0 | — | -7,432 |
| AMAZON COM INC(AMZN) | 257,625 | 218,547 | -39,078 | 56,520 | 47,986 | 1.45% | -8,534 |
| LEGEND BIOTECH CORP(LEGN) | 3,774,009 | 3,818,009 | +44,000 | 133,940 | 124,505 | 3.77% | -9,434 |
| KYMERA THERAPEUTICS INC(KYMR) | 275,000 | 0 | -275,000 | 12,001 | 0 | — | -12,001 |
| MODERNA INC(MRNA) | 517,163 | 0 | -517,163 | 14,269 | 0 | — | -14,269 |
| 89BIO INC | 14,210,000 | 8,280,000 | -5,930,000 | 139,542 | 121,716 | 3.69% | -17,826 |