Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q3 2025 ▲▼ | Q4 2025 ▲▼ | Change ▲▼ | Q3 2025 ▲▼ | Q4 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Arcutis Biotherapeutics, Inc.(ARQT) | 10,478,000 | 11,964,000 | +1,486,000 | $197.51M | $347.43M | 8.66% | +$149.92M |
| Benitec Biopharma Inc.(BNTC) | 9,876,506 | 11,548,351 | +1,671,845 | $138.57M | $155.56M | 3.88% | +$16.99M |
| Legend Biotech CorporationADS(LEGN) | 3,818,009 | 6,608,629 | +2,790,620 | $124.51M | $143.67M | 3.58% | +$19.17M |
| EyePoint, Inc.(EYPT) | 6,192,715 | 7,827,685 | +1,634,970 | $88.18M | $143.01M | 3.57% | +$54.83M |
| Arcus Biosciences, Inc.(RCUS) | 3,688,858 | 5,188,858 | +1,500,000 | $50.17M | $123.65M | 3.08% | +$73.48M |
| Immatics N.V.SHS(IMTX) | 12,030,129 | 11,190,129 | -840,000 | $102.50M | $117.50M | 2.93% | +$15.00M |
| Biohaven Ltd.(BHVN) | 5,620,271 | 10,286,937 | +4,666,666 | $84.36M | $116.14M | 2.90% | +$31.78M |
| Meta Platforms, Inc.CL A(META) | 170,973 | 169,069 | -1,904 | $125.56M | $111.60M | 2.78% | -$13.96M |
| Apellis Pharmaceuticals Inc COM | 2,878,000 | 4,139,426 | +1,261,426 | $65.13M | $103.98M | 2.59% | +$38.85M |
| NVIDIA Corporation(NVDA) | 483,535 | 530,900 | +47,365 | $90.22M | $99.01M | 2.47% | +$8.79M |
| The Coca-Cola Company(KO) | 1,455,080 | 1,382,750 | -72,330 | $96.50M | $96.67M | 2.41% | +$167.1K |
| GE Aerospace(GE) | 310,262 | 310,262 | 0 | $93.33M | $95.57M | 2.38% | +$2.24M |
| Amazon.com, Inc.(AMZN) | 218,547 | 406,146 | +187,599 | $47.99M | $93.75M | 2.34% | +$45.76M |
| Palvella Therapeutics, Inc.(PVLA) | 822,400 | 892,400 | +70,000 | $51.56M | $93.41M | 2.33% | +$41.85M |
| Kura Oncology, Inc.(KURA) | 8,116,000 | 8,575,422 | +459,422 | $71.83M | $89.10M | 2.22% | +$17.27M |
| Bank America Corp | 1,160,330 | 1,517,630 | +357,300 | $59.86M | $83.47M | 2.08% | +$23.61M |
| Advanced Micro Devices, Inc.(AMD) | 398,799 | 389,576 | -9,223 | $64.52M | $83.43M | 2.08% | +$18.91M |
| The Home Depot, Inc.(HD) | 197,311 | 240,861 | +43,550 | $79.95M | $82.88M | 2.07% | +$2.93M |
| ArriVent BioPharma, Inc.(AVBP) | 3,703,452 | 4,106,035 | +402,583 | $68.33M | $82.61M | 2.06% | +$14.28M |
| Taiwan Semiconductor Manufacturing Company LimitedADS(TSM) | 277,201 | 271,401 | -5,800 | $77.42M | $82.48M | 2.06% | +$5.06M |
| Sysco Corporation(SYY) | 0 | 1,083,790 | +1,083,790 | $0 | $79.86M | 1.99% | +$79.86M |
| Apollo Global Management, Inc.(APO) | 431,260 | 542,890 | +111,630 | $57.47M | $78.59M | 1.96% | +$21.11M |
| Microsoft Corporation(MSFT) | 109,455 | 159,695 | +50,240 | $56.69M | $77.23M | 1.93% | +$20.54M |
| Kalvista Pharmaceuticals Inc | 4,768,712 | 4,768,712 | 0 | $58.08M | $77.01M | 1.92% | +$18.93M |
| Compass Therapeutics, Inc.(CMPX) | 14,101,159 | 14,182,379 | +81,220 | $49.35M | $76.16M | 1.90% | +$26.81M |
| Fulcrum Therapeutics, Inc.(FULC) | 5,381,000 | 6,561,111 | +1,180,111 | $49.51M | $74.21M | 1.85% | +$24.70M |
| ServiceNow, Inc.(NOW) | 22,000 | 389,445 | +367,445 | $20.25M | $59.66M | 1.49% | +$39.41M |
| Danaher Corporation(DHR) | 255,800 | 244,300 | -11,500 | $50.71M | $55.93M | 1.39% | +$5.21M |
| Mineralys Therapeutics, Inc.(MLYS) | 2,132,133 | 1,538,662 | -593,471 | $80.85M | $55.84M | 1.39% | -$25.01M |
| Erasca, Inc.(ERAS) | 14,502,004 | 14,502,004 | 0 | $31.61M | $53.95M | 1.34% | +$22.33M |
| Salesforce, Inc.(CRM) | 125,250 | 199,900 | +74,650 | $29.68M | $52.96M | 1.32% | +$23.27M |
| Monte Rosa Therapeutics, Inc.(GLUE) | 3,360,000 | 3,360,000 | 0 | $24.90M | $52.68M | 1.31% | +$27.79M |
| Capricor Therapeutics, Inc.(CAPR) | 0 | 1,785,610 | +1,785,610 | $0 | $51.53M | 1.28% | +$51.53M |
| Ultragenyx Pharmaceutical Inc.(RARE) | 2,019,000 | 2,019,000 | 0 | $60.73M | $46.44M | 1.16% | -$14.29M |
| Oracle Corporation(ORCL) | 226,318 | 226,318 | 0 | $63.65M | $44.11M | 1.10% | -$19.54M |
| MGM Resorts International(MGM) | 0 | 1,202,070 | +1,202,070 | $0 | $43.86M | 1.09% | +$43.86M |
| Capital One Financial Corporation(COF) | 238,770 | 171,970 | -66,800 | $50.76M | $41.68M | 1.04% | -$9.08M |
| Tesla, Inc.(TSLA) | 91,252 | 91,252 | 0 | $40.58M | $41.04M | 1.02% | +$456.3K |
| Advisorshares TrPURE US CANNABIS PURE US CANN ETF | 7,167,000 | 8,669,600 | +1,502,600 | $34.33M | $40.92M | 1.02% | +$6.59M |
| UnitedHealth Group Incorporated(UNH) | 96,220 | 111,320 | +15,100 | $33.22M | $36.75M | 0.92% | +$3.52M |
| Ferguson Enterprises Inc.(FERG) | 306,260 | 159,190 | -147,070 | $68.78M | $35.44M | 0.88% | -$33.34M |
| Boston Scientific Corporation(BSX) | 353,561 | 353,561 | 0 | $34.52M | $33.71M | 0.84% | -$806.1K |
| Contineum Therapeutics, Inc.CL A(CTNM) | 1,720,000 | 2,841,334 | +1,121,334 | $20.21M | $32.48M | 0.81% | +$12.27M |
| Zura Bio LimitedCL A(ZURA) | 5,472,891 | 5,567,001 | +94,110 | $23.70M | $29.17M | 0.73% | +$5.47M |
| uniQure N.V.SHS(QURE) | 0 | 1,216,734 | +1,216,734 | $0 | $29.12M | 0.73% | +$29.12M |
| ProKidney Corp.CL A(PROK) | 12,341,266 | 12,341,266 | 0 | $29.87M | $27.64M | 0.69% | -$2.22M |
| Coherent Corp.(COHR) | 0 | 137,930 | +137,930 | $0 | $25.46M | 0.63% | +$25.46M |
| Chipotle Mexican Grill, Inc.(CMG) | 0 | 686,300 | +686,300 | $0 | $25.39M | 0.63% | +$25.39M |
| Aura Biosciences, Inc.(AURA) | 4,372,884 | 4,372,884 | 0 | $27.02M | $23.83M | 0.59% | -$3.19M |
| Tango Therapeutics, Inc.(TNGX) | 0 | 2,662,227 | +2,662,227 | $0 | $23.59M | 0.59% | +$23.59M |
| Biogen Inc.(BIIB) | 168,190 | 132,290 | -35,900 | $23.56M | $23.28M | 0.58% | -$278.3K |
| DICK'S Sporting Goods, Inc.(DKS) | 128,290 | 114,300 | -13,990 | $28.51M | $22.63M | 0.56% | -$5.88M |
| The Goldman Sachs Group, Inc.(GS) | 24,108 | 24,108 | 0 | $19.20M | $21.19M | 0.53% | +$1.99M |
| Johnson & Johnson(JNJ) | 132,786 | 98,786 | -34,000 | $24.62M | $20.44M | 0.51% | -$4.18M |
| Insmed Incorporated(INSM) | 217,783 | 109,313 | -108,470 | $31.36M | $19.02M | 0.47% | -$12.34M |
| Abeona Therapeutics Inc.(ABEO) | 2,676,000 | 2,676,000 | 0 | $14.13M | $14.10M | 0.35% | -$26.8K |
| Lexeo Therapeutics, Inc.(LXEO) | 0 | 1,250,000 | +1,250,000 | $0 | $12.41M | 0.31% | +$12.41M |
| Rocket Pharmaceuticals, Inc.(RCKT) | 3,843,333 | 2,992,735 | -850,598 | $12.53M | $10.50M | 0.26% | -$2.02M |
| Molecular Partners AGADS(MOLN) | 2,221,494 | 2,221,494 | 0 | $8.24M | $9.68M | 0.24% | +$1.44M |
| Endeavour Silver Corp.(EXK) | 94,100 | 94,100 | 0 | $5.15M | $9.56M | 0.24% | +$4.41M |
| Whitehawk Therapeutics, Inc.(WHWK) | 3,700,000 | 3,700,000 | 0 | $7.03M | $8.95M | 0.22% | +$1.92M |
| InflaRx N.V.(IFRX) | 6,483,910 | 7,933,910 | +1,450,000 | $8.69M | $8.01M | 0.20% | -$675.2K |
| Thermo Fisher Scientific Inc.(TMO) | 13,400 | 13,400 | 0 | $6.50M | $7.76M | 0.19% | +$1.27M |
| Abbott Labs | 51,020 | 51,020 | 0 | $6.83M | $6.39M | 0.16% | -$441.3K |
| Moderna, Inc.(MRNA) | 0 | 205,593 | +205,593 | $0 | $6.06M | 0.15% | +$6.06M |
| Kezar Life Sciences Inc COM NEW | 716,759 | 716,759 | 0 | $2.80M | $4.51M | 0.11% | +$1.71M |
| Cencora Inc | 12,488 | 12,488 | 0 | $3.90M | $4.22M | 0.11% | +$314.9K |
| United Therapeutics Corporation(UTHR) | 7,500 | 7,500 | 0 | $3.14M | $3.65M | 0.09% | +$510.3K |
| Intuitive Surgical, Inc.(ISRG) | 5,200 | 5,200 | 0 | $2.33M | $2.95M | 0.07% | +$619.5K |
| Mettler-Toledo International Inc.(MTD) | 1,964 | 1,964 | 0 | $2.41M | $2.74M | 0.07% | +$327.2K |
| Medtronic plcSHS(MDT) | 25,060 | 25,060 | 0 | $2.39M | $2.41M | 0.06% | +$20.6K |
| Natera, Inc.(NTRA) | 10,100 | 10,100 | 0 | $1.63M | $2.31M | 0.06% | +$688.0K |
| DexCom, Inc.(DXCM) | 31,680 | 31,680 | 0 | $2.13M | $2.10M | 0.05% | -$29.1K |
| Stryker Corporation(SYK) | 5,860 | 5,860 | 0 | $2.17M | $2.06M | 0.05% | -$106.7K |
| Medline Inc.CL A(MDLN) | 0 | 42,500 | +42,500 | $0 | $1.78M | 0.04% | +$1.78M |
| IQVIA Holdings Inc.(IQV) | 7,175 | 7,175 | 0 | $1.36M | $1.62M | 0.04% | +$254.5K |
| McKesson Corporation(MCK) | 1,830 | 1,830 | 0 | $1.41M | $1.50M | 0.04% | +$87.4K |
| HCA Healthcare, Inc.(HCA) | 3,190 | 3,190 | 0 | $1.36M | $1.49M | 0.04% | +$129.7K |
| Waters Corporation(WAT) | 3,150 | 3,150 | 0 | $944.4K | $1.20M | 0.03% | +$252.1K |
| Edwards Lifesciences Corp | 11,100 | 11,100 | 0 | $863.2K | $946.3K | 0.02% | +$83.0K |
| Ionis Pharmaceuticals, Inc.(IONS) | 10,800 | 10,800 | 0 | $706.5K | $854.4K | 0.02% | +$147.9K |
| Agilent Technologies, Inc.(A) | 4,990 | 4,990 | 0 | $640.5K | $679.0K | 0.02% | +$38.5K |
| ResMed Inc.(RMD) | 2,390 | 2,390 | 0 | $654.2K | $575.7K | 0.01% | -$78.5K |
| Veralto Corporation(VLTO) | 5,475 | 5,475 | 0 | $583.7K | $546.3K | 0.01% | -$37.4K |
| Viridian Therapeutics, Inc.(VRDN) | 0 | 16,700 | +16,700 | $0 | $519.7K | 0.01% | +$519.7K |
| STERIS plcSHS USD(STE) | 1,530 | 1,530 | 0 | $378.6K | $387.9K | 0.01% | +$9.3K |
| Sarepta Therapeutics, Inc.(SRPT) | 17,888 | 17,888 | 0 | $344.7K | $384.9K | 0.01% | +$40.2K |
| Replimune Group, Inc.(REPL) | 0 | 36,038 | +36,038 | $0 | $350.3K | 0.01% | +$350.3K |
| Zimmer Biomet Holdings, Inc.(ZBH) | 3,260 | 3,260 | 0 | $321.1K | $293.1K | 0.01% | -$28.0K |
| Charles River Laboratories International, Inc.(CRL) | 0 | 1,010 | +1,010 | $0 | $201.5K | 0.01% | +$201.5K |
| 89bio Inc | 8,280,000 | 0 | -8,280,000 | $121.72M | $0 | — | -$121.72M |
| Avantor, Inc.(AVTR) | 71,850 | 0 | -71,850 | $896.7K | $0 | — | -$896.7K |
| Avidity Biosciences Inc | 750,000 | 0 | -750,000 | $32.68M | $0 | — | -$32.68M |
| Elanco Animal Health Incorporated(ELAN) | 253,600 | 0 | -253,600 | $5.11M | $0 | — | -$5.11M |
| Lakefront Biotherapeutics NVADR(LKFT) | 37,111 | 0 | -37,111 | $1.29M | $0 | — | -$1.29M |
| Keurig Dr Pepper Inc.(KDP) | 1,570,000 | 0 | -1,570,000 | $40.05M | $0 | — | -$40.05M |
| Marvell Technology, Inc.(MRVL) | 272,300 | 0 | -272,300 | $22.89M | $0 | — | -$22.89M |
| Merck & Co., Inc.(MRK) | 219,178 | 0 | -219,178 | $18.40M | $0 | — | -$18.40M |
| PACS Group, Inc.(PACS) | 20,000 | 0 | -20,000 | $274.6K | $0 | — | -$274.6K |
| Pinterest, Inc.CL A(PINS) | 497,185 | 0 | -497,185 | $15.99M | $0 | — | -$15.99M |