Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q3 2025 ▲▼ | Q4 2025 ▲▼ | Change ▲▼ | Q3 2025 ▲▼ | Q4 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| TERNS PHARMACEUTICALS INC | 502,797 | 637,095 | +134,298 | 3,776 | 25,739 | 17.48% | +21,963 |
| PRAXIS PRECISION MEDICINES I(PRAX) | 49,751 | 83,036 | +33,285 | 2,637 | 24,474 | 16.62% | +21,837 |
| CIDARA THERAPEUTICS INC | 141,529 | 89,145 | -52,384 | 13,553 | 19,691 | 13.37% | +6,138 |
| COMPASS THERAPEUTICS INC | 840,090 | 1,093,300 | +253,210 | 2,940 | 5,871 | 3.99% | +2,931 |
| MINERVA NEUROSCIENCES | 0 | 709,500 | +709,500 | 0 | 2,852 | 1.94% | +2,852 |
| TANGO THERAPEUTICS INC(TNGX) | 0 | 282,732 | +282,732 | 0 | 2,505 | 1.70% | +2,505 |
| WHITEHAWK THERAPEUTICS INC | 3,410,402 | 3,410,402 | 0 | 6,480 | 8,253 | 5.60% | +1,773 |
| SURROZEN INC | 178,415 | 178,415 | 0 | 2,299 | 4,032 | 2.74% | +1,733 |
| JAZZ PHARMACEUTICALS PLC(JAZZ) | 25,114 | 29,008 | +3,894 | 3,310 | 4,931 | 3.35% | +1,621 |
| BRIGHT MINDS BIOSCIENCES INC | 84,875 | 84,477 | -398 | 5,149 | 6,593 | 4.48% | +1,444 |
| DESIGN THERAPEUTICS INC(DSGN) | 0 | 150,906 | +150,906 | 0 | 1,415 | 0.96% | +1,415 |
| TAYSHA GENE THERAPIES INC(TSHA) | 454,827 | 454,827 | 0 | 1,487 | 2,502 | 1.70% | +1,014 |
| MAZE THERAPEUTICS INC(MAZE) | 0 | 20,000 | +20,000 | 0 | 829 | 0.56% | +829 |
| MOONLAKE IMMUNOTHERAPEUTICS(MLTX) | 0 | 59,280 | +59,280 | 0 | 781 | 0.53% | +781 |
| SUTRO BIOPHARMA INC | 0 | 67,451 | +67,451 | 0 | 780 | 0.53% | +780 |
| INHIBRX BIOSCIENCES INC(INBX) | 16,377 | 16,377 | 0 | 552 | 1,294 | 0.88% | +742 |
| ZYMEWORKS INC(ZYME) | 80,143 | 80,143 | 0 | 1,369 | 2,110 | 1.43% | +741 |
| PASITHEA THERAPEUTICS CORP | 0 | 450,000 | +450,000 | 0 | 581 | 0.39% | +581 |
| REVOLUTION MEDICINES INC(RVMD) | 8,411 | 8,411 | 0 | 393 | 670 | 0.45% | +277 |
| OCULIS HOLDING AG | 101,777 | 101,777 | 0 | 1,789 | 2,032 | 1.38% | +243 |
| LB PHARMACEUTICALS INC(LBRX) | 30,000 | 30,000 | 0 | 474 | 668 | 0.45% | +194 |
| UNITED THERAPEUTICS CORP(UTHR) | 2,296 | 2,296 | 0 | 963 | 1,119 | 0.76% | +156 |
| UNICYCIVE THERAPEUTICS INC | 59,985 | 59,985 | 0 | 262 | 346 | 0.23% | +85 |
| NUVATION BIO INC -CW27(NUVB) | 90,832 | 90,832 | 0 | 18 | 30 | 0.02% | +12 |
| VERASTEM INC | 143,446 | 143,446 | 0 | 1,267 | 1,107 | 0.75% | -159 |
| DIANTHUS THERAPEUTICS INC(DNTH) | 25,000 | 16,708 | -8,292 | 984 | 689 | 0.47% | -295 |
| AMYLYX PHARMACEUTICALS INC(AMLX) | 333,258 | 333,258 | 0 | 4,529 | 4,026 | 2.73% | -503 |
| FULCRUM THERAPEUTICS INC | 57,141 | 0 | -57,141 | 526 | 0 | — | -526 |
| ARGEN SE - ADR(ARGX) | 6,379 | 4,851 | -1,528 | 4,705 | 4,079 | 2.77% | -625 |
| OCULAR THERAPEUTIX INC(OCUL) | 1,165,206 | 1,052,995 | -112,211 | 13,621 | 12,783 | 8.68% | -838 |
| INSMED INC(INSM) | 38,592 | 25,878 | -12,714 | 5,558 | 4,504 | 3.06% | -1,054 |
| COGENT BIOSCIENCES INC(COGT) | 102,907 | 0 | -102,907 | 1,478 | 0 | — | -1,478 |
| KRYSTAL BIOTECH INC(KRYS) | 10,573 | 0 | -10,573 | 1,866 | 0 | — | -1,866 |
| ASCENDIS PHA-ADR(ASND) | 9,792 | 0 | -9,792 | 1,947 | 0 | — | -1,947 |
| TOURMALINE BIO INC | 268,451 | 0 | -268,451 | 12,840 | 0 | — | -12,840 |