Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q4 2024 ▲▼ | Q1 2025 ▲▼ | Change ▲▼ | Q4 2024 ▲▼ | Q1 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| BRIDGEBIO PHARMA INC(BBIO) | 1,600,000 | 2,000,000 | +400,000 | 43,904 | 69,140 | 5.23% | +25,236 |
| GH RESEARCH PLC(GHRS) | 593,043 | 2,009,482 | +1,416,439 | 4,151 | 22,165 | 1.68% | +18,013 |
| ARS PHARMACEUTICALS INC(SPRY) | 500,000 | 1,600,000 | +1,100,000 | 5,275 | 20,128 | 1.52% | +14,853 |
| METSERA INC | 0 | 400,000 | +400,000 | 0 | 10,888 | 0.82% | +10,888 |
| KORRO BIO INC(KRRO) | 0 | 380,303 | +380,303 | 0 | 6,621 | 0.50% | +6,621 |
| AARDVARK THERAPEUTICS INC | 0 | 800,189 | +800,189 | 0 | 6,009 | 0.45% | +6,009 |
| PLIANT THERAPEUTICS INC(PLRX) | 0 | 3,000,000 | +3,000,000 | 0 | 4,050 | 0.31% | +4,050 |
| HELIX ACQUISITION CORP II | 2,909,000 | 2,909,000 | 0 | 30,545 | 32,872 | 2.49% | +2,327 |
| AXSOME THERAPEUTICS INC(AXSM) | 325,000 | 250,000 | -75,000 | 27,498 | 29,158 | 2.21% | +1,659 |
| BRIGHT MINDS BIOSCIENCES INC(DRUG) | 1,059,331 | 1,059,331 | 0 | 38,157 | 38,210 | 2.89% | +53 |
| MERUS N V | 740,000 | 740,000 | 0 | 31,117 | 31,147 | 2.36% | +30 |
| RAPT THERAPEUTICS INC | 200,000 | 0 | -200,000 | 316 | 0 | — | -316 |
| ENLIVEN THERAPEUTICS INC | 250,000 | 250,000 | 0 | 5,625 | 4,920 | 0.37% | -705 |
| EDGEWISE THERAPEUTICS INC(EWTX) | 3,406,534 | 4,101,992 | +695,458 | 90,954 | 90,244 | 6.83% | -711 |
| KALA BIO INC(KALA) | 603,027 | 603,027 | 0 | 4,185 | 3,455 | 0.26% | -730 |
| ARTIVA BIOTHERAPEUTICS INC(ARTV) | 103,633 | 0 | -103,633 | 1,045 | 0 | — | -1,045 |
| STOKE THERAPEUTICS INC(STOK) | 254,161 | 254,161 | 0 | 2,803 | 1,690 | 0.13% | -1,113 |
| BIOHAVEN LTD(BHVN) | 55,539 | 10,000 | -45,539 | 2,074 | 240 | 0.02% | -1,834 |
| VERVE THERAPEUTICS INC | 350,000 | 0 | -350,000 | 1,974 | 0 | — | -1,974 |
| ABIVAX SA(ABVX) | 2,130,000 | 2,130,000 | 0 | 15,592 | 13,313 | 1.01% | -2,279 |
| OMEROS CORP(OMER) | 300,000 | 0 | -300,000 | 2,964 | 0 | — | -2,964 |
| UROGEN PHARMA LTD(URGN) | 300,000 | 0 | -300,000 | 3,195 | 0 | — | -3,195 |
| CG ONCOLOGY INC(CGON) | 775,000 | 775,000 | 0 | 22,227 | 18,980 | 1.44% | -3,247 |
| CARGO THERAPEUTICS INC | 1,182,563 | 3,381,277 | +2,198,714 | 17,053 | 13,762 | 1.04% | -3,291 |
| Y-MABS THERAPEUTICS INC | 425,000 | 0 | -425,000 | 3,328 | 0 | — | -3,328 |
| ALUMIS INC | 2,147,396 | 2,147,396 | 0 | 16,879 | 13,185 | 1.00% | -3,694 |
| ARCUTIS BIOTHERAPEUTICS INC(ARQT) | 1,825,000 | 1,350,000 | -475,000 | 25,422 | 21,114 | 1.60% | -4,308 |
| VYNE THERAPEUTICS INC(YARW) | 1,394,336 | 0 | -1,394,336 | 4,671 | 0 | — | -4,671 |
| INSMED INC(INSM) | 650,000 | 525,000 | -125,000 | 44,876 | 40,052 | 3.03% | -4,824 |
| ENGENE HOLDINGS INC COM | 2,323,595 | 2,323,595 | 0 | 15,452 | 10,410 | 0.79% | -5,042 |
| PHARVARIS N V COM | 1,466,460 | 1,466,460 | 0 | 28,112 | 23,023 | 1.74% | -5,089 |
| BIOAGE LABS INC(BIOA) | 2,629,529 | 2,629,529 | 0 | 15,225 | 9,887 | 0.75% | -5,338 |
| BIOMEA FUSION INC(BMEA) | 3,570,872 | 3,570,872 | 0 | 13,855 | 7,606 | 0.58% | -6,249 |
| TARSUS PHARMACEUTICALS INC(TARS) | 500,000 | 400,000 | -100,000 | 27,685 | 20,548 | 1.56% | -7,137 |
| IMMUNITYBIO INC(IBRX) | 3,000,000 | 0 | -3,000,000 | 7,680 | 0 | — | -7,680 |
| MBX BIOSCIENCES INC(MBX) | 700,000 | 700,000 | 0 | 12,901 | 5,166 | 0.39% | -7,735 |
| ONKURE THERAPEUTICS INC(OKUR) | 1,837,739 | 1,837,739 | 0 | 15,805 | 7,902 | 0.60% | -7,902 |
| CENTESSA PHARMACEUTICALS PLC | 2,561,600 | 2,261,600 | -300,000 | 42,907 | 32,522 | 2.46% | -10,385 |
| SEPTERNA INC(SEPN) | 560,000 | 0 | -560,000 | 12,824 | 0 | — | -12,824 |
| RHYTHM PHARMACEUTICALS INC(RYTM) | 400,000 | 150,000 | -250,000 | 22,392 | 7,946 | 0.60% | -14,446 |
| CORBUS PHARMACEUTICALS HLDGS(CRBP) | 2,375,000 | 2,375,000 | 0 | 28,025 | 12,611 | 0.95% | -15,414 |
| ARRIVENT BIOPHARMA INC(AVBP) | 585,462 | 0 | -585,462 | 15,597 | 0 | — | -15,597 |
| EYEPOINT PHARMACEUTICALS INC(EYPT) | 8,325,000 | 8,325,000 | 0 | 62,021 | 45,122 | 3.42% | -16,900 |
| AVIDITY BIOSCIENCES INC | 1,050,000 | 400,000 | -650,000 | 30,534 | 11,808 | 0.89% | -18,726 |
| RAPPORT THERAPEUTICS INC(RAPP) | 2,940,921 | 2,940,921 | 0 | 52,172 | 29,497 | 2.23% | -22,675 |
| NEWAMSTERDAM PHARMA COMPANY ORDINARY SHARES | 3,250,000 | 2,825,000 | -425,000 | 83,525 | 57,828 | 4.38% | -25,697 |
| VAXCYTE INC(PCVX) | 425,000 | 175,000 | -250,000 | 34,791 | 6,608 | 0.50% | -28,182 |
| ARCELLX INC COMMON STOCK | 1,300,000 | 1,050,000 | -250,000 | 99,697 | 68,880 | 5.22% | -30,817 |
| CRINETICS PHARMACEUTICALS IN(CRNX) | 1,000,000 | 600,000 | -400,000 | 51,130 | 20,124 | 1.52% | -31,006 |
| JANUX THERAPEUTICS INC(JANX) | 2,100,000 | 2,000,000 | -100,000 | 112,434 | 54,000 | 4.09% | -58,434 |
| PRAXIS PRECISION MEDICINES I(PRAX) | 1,693,219 | 1,745,000 | +51,781 | 130,310 | 66,083 | 5.00% | -64,227 |
| MOONLAKE IMMUNOTHERAPEUTICS(MLTX) | 8,494,151 | 8,494,151 | 0 | 459,958 | 331,866 | 25.13% | -128,092 |