Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q4 2025 ▲▼ | Q1 2026 ▲▼ | Change ▲▼ | Q4 2025 ▲▼ | Q1 2026 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Praxis Precision Medicines, Inc.(PRAX) | 950,000 | 885,500 | -64,500 | $280.00M | $285.30M | 14.38% | +$5.30M |
| BridgeBio Oncology Therapeutics, Inc.(BBOT) | 17,878,594 | 17,878,594 | 0 | $223.84M | $160.01M | 8.07% | -$63.83M |
| EyePoint, Inc.(EYPT) | 8,265,000 | 8,265,000 | 0 | $151.00M | $106.54M | 5.37% | -$44.47M |
| Edgewise Therapeutics, Inc.(EWTX) | 3,285,000 | 3,260,000 | -25,000 | $81.52M | $102.69M | 5.18% | +$21.17M |
| Erasca, Inc.(ERAS) | 0 | 5,800,000 | +5,800,000 | $0 | $93.84M | 4.73% | +$93.84M |
| Rapport Therapeutics, Inc.(RAPP) | 3,027,521 | 2,957,521 | -70,000 | $91.85M | $92.54M | 4.67% | +$685.8K |
| Alumis Inc | 3,635,596 | 3,949,241 | +313,645 | $35.48M | $87.00M | 4.39% | +$51.52M |
| ABIVAX Société AnonymeADS(ABVX) | 1,350,000 | 760,000 | -590,000 | $182.05M | $84.63M | 4.27% | -$97.43M |
| MoonLake ImmunotherapeuticsCL A(MLTX) | 4,355,433 | 4,480,433 | +125,000 | $57.40M | $83.52M | 4.21% | +$26.11M |
| Dianthus Therapeutics, Inc.(DNTH) | 0 | 950,000 | +950,000 | $0 | $79.72M | 4.02% | +$79.72M |
| Bright Minds Biosciences Inc.(DRUG) | 1,059,331 | 1,059,331 | 0 | $82.67M | $77.30M | 3.90% | -$5.37M |
| BridgeBio Pharma, Inc.(BBIO) | 1,200,000 | 850,000 | -350,000 | $91.79M | $63.12M | 3.18% | -$28.67M |
| Olema Pharmaceuticals, Inc.(OLMA) | 2,750,000 | 3,900,000 | +1,150,000 | $68.75M | $58.15M | 2.93% | -$10.60M |
| BioAge Labs, Inc.(BIOA) | 2,040,605 | 2,890,605 | +850,000 | $27.00M | $50.56M | 2.55% | +$23.56M |
| Centessa Pharmaceuticals PlcADS | 1,325,000 | 1,050,000 | -275,000 | $33.14M | $41.71M | 2.10% | +$8.57M |
| Damora Therapeutics, Inc.(DMRA) | 0 | 1,525,000 | +1,525,000 | $0 | $39.50M | 1.99% | +$39.50M |
| MBX Biosciences, Inc.(MBX) | 1,120,000 | 1,120,000 | 0 | $35.32M | $33.43M | 1.69% | -$1.89M |
| Insmed Incorporated(INSM) | 275,000 | 190,000 | -85,000 | $47.86M | $31.07M | 1.57% | -$16.79M |
| Newamsterdam Pharma Company ORDINARY SHARES | 1,000,000 | 950,000 | -50,000 | $35.08M | $30.41M | 1.53% | -$4.67M |
| Tango Therapeutics, Inc.(TNGX) | 0 | 1,425,000 | +1,425,000 | $0 | $29.81M | 1.50% | +$29.81M |
| Pharvaris N V COM | 1,083,000 | 1,000,000 | -83,000 | $30.05M | $28.25M | 1.42% | -$1.80M |
| Oruka Therapeutics, Inc.(ORKA) | 533,340 | 533,340 | 0 | $16.17M | $26.16M | 1.32% | +$9.99M |
| AgomAb Therapeutics NVADS(AGMB) | 0 | 2,465,348 | +2,465,348 | $0 | $25.86M | 1.30% | +$25.86M |
| Maze Therapeutics, Inc.(MAZE) | 0 | 750,000 | +750,000 | $0 | $22.39M | 1.13% | +$22.39M |
| Corbus Pharmaceuticals Holdings, Inc.(CRBP) | 2,344,971 | 2,344,971 | 0 | $19.09M | $22.02M | 1.11% | +$2.93M |
| Ascendis Pharma A/SADR(ASND) | 100,000 | 95,000 | -5,000 | $21.32M | $21.73M | 1.10% | +$405.4K |
| Roivant Sciences Ltd.SHS(ROIV) | 0 | 750,000 | +750,000 | $0 | $20.77M | 1.05% | +$20.77M |
| Adlai Nortye Group Ltd.ADS(ANL) | 0 | 2,897,857 | +2,897,857 | $0 | $20.05M | 1.01% | +$20.05M |
| Terns Pharmaceuticals Inc | 0 | 300,000 | +300,000 | $0 | $15.82M | 0.80% | +$15.82M |
| Tarsus Pharmaceuticals, Inc.(TARS) | 250,000 | 225,000 | -25,000 | $20.47M | $15.78M | 0.80% | -$4.69M |
| Biohaven Ltd.(BHVN) | 10,000 | 1,760,000 | +1,750,000 | $112.9K | $14.89M | 0.75% | +$14.78M |
| Cabaletta Bio, Inc.(CABA) | 4,400,000 | 5,500,000 | +1,100,000 | $9.64M | $14.79M | 0.75% | +$5.16M |
| Helix Acquisition Corp. IIICL A(HLXC) | 0 | 1,297,500 | +1,297,500 | $0 | $13.18M | 0.66% | +$13.18M |
| Arcutis Biotherapeutics, Inc.(ARQT) | 500,000 | 450,000 | -50,000 | $14.52M | $10.60M | 0.53% | -$3.92M |
| Faeth Therapeutics, Inc.(FTH) | 0 | 306,222 | +306,222 | $0 | $9.65M | 0.49% | +$9.65M |
| Crinetics Pharmaceuticals In | 300,000 | 250,000 | -50,000 | $13.96M | $9.08M | 0.46% | -$4.88M |
| Zura Bio LimitedCL A(ZURA) | 0 | 1,450,000 | +1,450,000 | $0 | $8.63M | 0.43% | +$8.63M |
| Axsome Therapeutics, Inc.(AXSM) | 75,000 | 50,000 | -25,000 | $13.70M | $8.45M | 0.43% | -$5.25M |
| Structure Therapeutics IncADS | 0 | 175,000 | +175,000 | $0 | $8.44M | 0.43% | +$8.44M |
| Cogent Biosciences, Inc.(COGT) | 225,000 | 200,000 | -25,000 | $7.99M | $7.70M | 0.39% | -$294.0K |
| Monte Rosa Therapeutics, Inc.(GLUE) | 0 | 400,000 | +400,000 | $0 | $6.58M | 0.33% | +$6.58M |
| Arrowhead Pharmaceuticals, Inc.(ARWR) | 0 | 100,000 | +100,000 | $0 | $6.27M | 0.32% | +$6.27M |
| Vaxcyte, Inc.(PCVX) | 125,000 | 100,000 | -25,000 | $5.77M | $5.81M | 0.29% | +$43.5K |
| Amylyx Pharmaceuticals, Inc.(AMLX) | 400,000 | 350,000 | -50,000 | $4.83M | $4.87M | 0.25% | +$33.0K |
| Rallybio Corporation(RLYB) | 0 | 400,000 | +400,000 | $0 | $3.59M | 0.18% | +$3.59M |
| Context Therapeutics Inc.(CNTX) | 0 | 529,550 | +529,550 | $0 | $1.39M | 0.07% | +$1.39M |
| Engene Holdings Inc COM | 4,000,000 | 0 | -4,000,000 | $36.12M | $0 | — | -$36.12M |
| GH Research PLC(GHRS) | 1,300,000 | 0 | -1,300,000 | $16.51M | $0 | — | -$16.51M |
| Janux Therapeutics, Inc.(JANX) | 650,000 | 0 | -650,000 | $8.97M | $0 | — | -$8.97M |