Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q3 2023 ▲▼ | Q4 2023 ▲▼ | Change ▲▼ | Q3 2023 ▲▼ | Q4 2023 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| AMBRX BIOPHARMA INC | 0 | 11,231,000 | +11,231,000 | 0 | 159,929 | 7.66% | +159,929 |
| EYEPOINT PHARMACEUTICALS INC(EYPT) | 3,200,000 | 6,038,235 | +2,838,235 | 25,568 | 139,544 | 6.68% | +113,976 |
| RAYZEBIO INC | 1,182,263 | 1,213,478 | +31,215 | 26,246 | 75,442 | 3.61% | +49,196 |
| MOONLAKE IMMUNOTHERAPEUTICS(MLTX) | 8,142,100 | 8,494,151 | +352,051 | 464,100 | 512,962 | 24.56% | +48,862 |
| ALX ONCOLOGY HLDGS INC(ALXO) | 612,079 | 3,142,079 | +2,530,000 | 2,938 | 46,786 | 2.24% | +43,848 |
| AUTOLUS THERAPEUTICS PLC(AUTL) | 392,167 | 5,450,000 | +5,057,833 | 914 | 35,098 | 1.68% | +34,184 |
| CARGO THERAPEUTICS INC | 0 | 1,182,563 | +1,182,563 | 0 | 27,376 | 1.31% | +27,376 |
| ALPINE IMMUNE SCIENCES INC | 1,900,000 | 2,550,000 | +650,000 | 21,755 | 48,603 | 2.33% | +26,848 |
| SYNDAX PHARMACEUTICALS INC(SNDX) | 0 | 1,175,000 | +1,175,000 | 0 | 25,392 | 1.22% | +25,392 |
| KORRO BIO INC(KRRO) | 0 | 529,170 | +529,170 | 0 | 25,363 | 1.21% | +25,363 |
| ABIVAX SA(ABVX) | 0 | 2,130,000 | +2,130,000 | 0 | 22,791 | 1.09% | +22,791 |
| HARPOON THERAPEUTICS INC | 54,060 | 2,349,060 | +2,295,000 | 218 | 22,551 | 1.08% | +22,333 |
| SPYRE THERAPEUTICS INC(SYRE) | 0 | 937,080 | +937,080 | 0 | 20,166 | 0.97% | +20,166 |
| PHARVARIS N V COM | 1,361,460 | 1,711,460 | +350,000 | 28,414 | 48,006 | 2.30% | +19,593 |
| ARCELLX INC COMMON STOCK | 2,150,000 | 1,700,000 | -450,000 | 77,142 | 94,350 | 4.52% | +17,208 |
| NEUROGENE INC(NGNE) | 0 | 746,180 | +746,180 | 0 | 14,461 | 0.69% | +14,461 |
| MARINUS PHARMACEUTICALS INC | 2,625,000 | 3,250,000 | +625,000 | 21,131 | 35,328 | 1.69% | +14,196 |
| PRAXIS PRECISION MEDICINES I(PRAX) | 0 | 633,345 | +633,345 | 0 | 14,111 | 0.68% | +14,111 |
| BRIDGEBIO PHARMA INC(BBIO) | 4,662,530 | 3,344,179 | -1,318,351 | 122,951 | 135,005 | 6.46% | +12,054 |
| EDGEWISE THERAPEUTICS INC(EWTX) | 2,946,887 | 2,551,989 | -394,898 | 16,886 | 27,919 | 1.34% | +11,033 |
| CRINETICS PHARMACEUTICALS IN(CRNX) | 1,101,904 | 1,150,000 | +48,096 | 32,771 | 40,917 | 1.96% | +8,146 |
| VAXCYTE INC(PCVX) | 665,000 | 665,000 | 0 | 33,902 | 41,762 | 2.00% | +7,860 |
| RAPT THERAPEUTICS INC | 325,000 | 496,750 | +171,750 | 5,402 | 12,344 | 0.59% | +6,943 |
| AEROVATE THERAPEUTICS INC | 1,561,696 | 1,211,696 | -350,000 | 21,192 | 27,421 | 1.31% | +6,228 |
| RHYTHM PHARMACEUTICALS INC(RYTM) | 850,000 | 550,000 | -300,000 | 19,486 | 25,284 | 1.21% | +5,797 |
| LANTHEUS HLDGS INC(LNTH) | 0 | 75,000 | +75,000 | 0 | 4,650 | 0.22% | +4,650 |
| ROCKET PHARMACEUTICALS INC(RCKT) | 450,000 | 450,000 | 0 | 9,221 | 13,487 | 0.65% | +4,266 |
| INSMED INC(INSM) | 575,000 | 575,000 | 0 | 14,519 | 17,819 | 0.85% | +3,301 |
| VYNE THERAPEUTICS INC(YARW) | 0 | 1,394,336 | +1,394,336 | 0 | 3,249 | 0.16% | +3,249 |
| BIOMEA FUSION INC(BMEA) | 3,570,872 | 3,570,872 | 0 | 49,135 | 51,849 | 2.48% | +2,714 |
| IMMUNOVANT INC(IMVT) | 1,225,000 | 1,165,000 | -60,000 | 47,028 | 49,081 | 2.35% | +2,054 |
| AXONICS INC | 250,000 | 250,000 | 0 | 14,030 | 15,558 | 0.74% | +1,528 |
| STOKE THERAPEUTICS INC(STOK) | 1,087,807 | 1,087,807 | 0 | 4,286 | 5,722 | 0.27% | +1,436 |
| BIOHAVEN LTD(BHVN) | 81,963 | 81,963 | 0 | 2,132 | 3,508 | 0.17% | +1,376 |
| LONGBOARD PHARMACEUTICALS IN | 2,353,141 | 2,353,141 | 0 | 13,083 | 14,189 | 0.68% | +1,106 |
| BIOATLA INC(BCAB) | 1,181,115 | 1,181,115 | 0 | 2,008 | 2,906 | 0.14% | +898 |
| CENTESSA PHARMACEUTICALS PLC | 561,600 | 561,600 | 0 | 3,634 | 4,470 | 0.21% | +837 |
| NEUMORA THERAPEUTICS INC.(NMRA) | 92,293 | 92,293 | 0 | 1,302 | 1,574 | 0.08% | +271 |
| VERVE THERAPEUTICS INC | 350,000 | 350,000 | 0 | 4,641 | 4,879 | 0.23% | +238 |
| IDEAYA BIOSCIENCES INC(IDYA) | 600,000 | 450,000 | -150,000 | 16,188 | 16,011 | 0.77% | -177 |
| ORCHARD THERAPEUTICS PLC | 25,664 | 0 | -25,664 | 198 | 0 | — | -198 |
| IMMUNEERING CORP | 4,204,364 | 4,204,364 | 0 | 32,290 | 30,902 | 1.48% | -1,387 |
| TARSUS PHARMACEUTICALS INC(TARS) | 2,621,422 | 2,221,422 | -400,000 | 46,583 | 44,984 | 2.15% | -1,599 |
| GH RESEARCH PLC(GHRS) | 593,043 | 593,043 | 0 | 5,960 | 3,440 | 0.16% | -2,520 |
| VIGIL NEUROSCIENCE INC | 616,786 | 0 | -616,786 | 3,324 | 0 | — | -3,324 |
| DISC MEDICINE INC(IRON) | 225,000 | 125,000 | -100,000 | 10,571 | 7,220 | 0.35% | -3,350 |
| COGENT BIOSCIENCES INC(COGT) | 1,000,000 | 0 | -1,000,000 | 9,750 | 0 | — | -9,750 |
| AVIDITY BIOSCIENCES INC | 1,762,115 | 0 | -1,762,115 | 11,242 | 0 | — | -11,242 |
| ZENTALIS PHARMACEUTICALS INC(ZNTL) | 700,000 | 0 | -700,000 | 14,042 | 0 | — | -14,042 |
| CYMABAY THERAPEUTICS INC | 3,850,000 | 1,800,000 | -2,050,000 | 57,404 | 42,516 | 2.04% | -14,887 |
| PRAXIS PRECISION MEDICINES I | 9,500,000 | 0 | -9,500,000 | 16,245 | 0 | — | -16,245 |
| ENLIVEN THERAPEUTICS INC | 1,216,712 | 0 | -1,216,712 | 16,620 | 0 | — | -16,620 |
| OLEMA PHARMACEUTICALS INC(OLMA) | 4,504,764 | 2,456,800 | -2,047,964 | 55,634 | 34,469 | 1.65% | -21,165 |
| ERASCA INC(ERAS) | 10,813,246 | 0 | -10,813,246 | 21,302 | 0 | — | -21,302 |
| KARUNA THERAPEUTICS INC | 140,000 | 0 | -140,000 | 23,673 | 0 | — | -23,673 |
| APELLIS PHARMACEUTICALS INC COM | 2,000,000 | 625,000 | -1,375,000 | 76,080 | 37,413 | 1.79% | -38,667 |
| CABALETTA BIO INC(CABA) | 2,879,424 | 0 | -2,879,424 | 43,825 | 0 | — | -43,825 |
| STRUCTURE THERAPEUTICS INC | 1,056,373 | 0 | -1,056,373 | 53,262 | 0 | — | -53,262 |
| AMBRX BIOPHARMA INC | 9,923,689 | 0 | -9,923,689 | 114,122 | 0 | — | -114,122 |