Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q4 2025 ▲▼ | Q1 2026 ▲▼ | Change ▲▼ | Q4 2025 ▲▼ | Q1 2026 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Zymeworks Inc.(ZYME) | 22,970,388 | 22,970,388 | 0 | $604.81M | $575.18M | 24.58% | -$29.63M |
| Anaptysbio Inc | 7,880,094 | 7,880,094 | 0 | $382.03M | $437.03M | 18.68% | +$55.00M |
| Jazz Pharmaceuticals plcSHS USD(JAZZ) | 1,706,469 | 1,706,469 | 0 | $290.10M | $322.61M | 13.79% | +$32.51M |
| Centessa Pharmaceuticals PlcADS | 3,115,000 | 6,000,000 | +2,885,000 | $77.91M | $238.32M | 10.18% | +$160.41M |
| Crinetics Pharmaceuticals In | 4,288,120 | 4,288,120 | 0 | $199.61M | $155.74M | 6.66% | -$43.87M |
| Aktis Oncology, Inc.COM ADDED(AKTS) | 0 | 4,824,469 | +4,824,469 | $0 | $86.31M | 3.69% | +$86.31M |
| ORIC Pharmaceuticals, Inc.(ORIC) | 6,728,116 | 6,728,116 | 0 | $55.04M | $85.25M | 3.64% | +$30.21M |
| CG Oncology, Inc.(CGON) | 772,000 | 1,102,000 | +330,000 | $32.05M | $74.58M | 3.19% | +$42.53M |
| CRISPR Therapeutics AGNAMEN AKT(CRSP) | 1,389,276 | 1,389,276 | 0 | $72.85M | $66.09M | 2.82% | -$6.77M |
| Eton Pharmaceuticals, Inc.(ETON) | 2,030,544 | 2,171,938 | +141,394 | $34.34M | $53.60M | 2.29% | +$19.27M |
| Lakefront Biotherapeutics NVADR(LKFT) | 1,667,119 | 1,667,119 | 0 | $54.51M | $50.01M | 2.14% | -$4.50M |
| Xencor, Inc.(XNCR) | 3,251,112 | 2,183,000 | -1,068,112 | $49.77M | $26.33M | 1.13% | -$23.45M |
| Neurogene Inc.(NGNE) | 1,271,342 | 1,271,342 | 0 | $26.19M | $25.63M | 1.10% | -$559.4K |
| BridgeBio Oncology Therapeutics, Inc.(BBOT) | 2,823,126 | 2,823,126 | 0 | $35.35M | $25.27M | 1.08% | -$10.08M |
| MBX Biosciences, Inc.(MBX) | 2,123,604 | 777,000 | -1,346,604 | $66.98M | $23.19M | 0.99% | -$43.79M |
| Relay Therapeutics, Inc.(RLAY) | 0 | 1,904,762 | +1,904,762 | $0 | $18.95M | 0.81% | +$18.95M |
| Zenas BioPharma, Inc.(ZBIO) | 789,500 | 789,500 | 0 | $28.67M | $15.43M | 0.66% | -$13.23M |
| Erasca, Inc.(ERAS) | 0 | 900,000 | +900,000 | $0 | $14.56M | 0.62% | +$14.56M |
| Eikon Therapeutics, Inc.COM ADDED(EIKN) | 0 | 732,606 | +732,606 | $0 | $7.75M | 0.33% | +$7.75M |
| Replimune Group, Inc.(REPL) | 0 | 1,000,000 | +1,000,000 | $0 | $7.65M | 0.33% | +$7.65M |
| Zura Bio LimitedCL A(ZURA) | 0 | 1,179,715 | +1,179,715 | $0 | $7.02M | 0.30% | +$7.02M |
| Phathom Pharmaceuticals, Inc.(PHAT) | 0 | 625,000 | +625,000 | $0 | $6.94M | 0.30% | +$6.94M |
| Mereo BioPharma Group plcADS(MREO) | 7,856,466 | 13,368,855 | +5,512,389 | $3.27M | $4.41M | 0.19% | +$1.14M |
| Stoke Therapeutics, Inc.(STOK) | 0 | 100,000 | +100,000 | $0 | $3.26M | 0.14% | +$3.26M |
| Prelude Therapeutics Incorporated(PRLD) | 0 | 947,049 | +947,049 | $0 | $3.24M | 0.14% | +$3.24M |
| iBio, Inc.(IBIO) | 2,228,000 | 1,583,000 | -645,000 | $4.30M | $3.01M | 0.13% | -$1.29M |
| Helix Acquisition Corp. IIICL A(HLXC) | 0 | 200,000 | +200,000 | $0 | $2.03M | 0.09% | +$2.03M |
| Atara Biotherapeutics Inc | 573,183 | 99,593 | -473,590 | $10.37M | $471.1K | 0.02% | -$9.90M |
| Surrozen, Inc.W EXP 08 01 203(SRZN) | 4,444 | 4,444 | 0 | $100.4K | $129.5K | 0.01% | +$29.0K |
| Aquestive Therapeutics Inc | 2,625,000 | 0 | -2,625,000 | $16.96M | $0 | — | -$16.96M |
| CAMP4 THERAPEUTICS CORPORATION(CAMP) | 325,000 | 0 | -325,000 | $1.99M | $0 | — | -$1.99M |
| Evolus, Inc.(EOLS) | 675,000 | 0 | -675,000 | $4.49M | $0 | — | -$4.49M |
| Immunome, Inc.(IMNM) | 2,855,590 | 0 | -2,855,590 | $61.34M | $0 | — | -$61.34M |
| MannKind Corporation(MNKD) | 1,660,000 | 0 | -1,660,000 | $9.41M | $0 | — | -$9.41M |
| Nuvation Bio Inc.W EXP 02 10 202(NUVB) | 963,333 | 0 | -963,333 | $8.63M | $0 | — | -$8.63M |
| Structure Therapeutics IncADS | 334,380 | 0 | -334,380 | $23.26M | $0 | — | -$23.26M |
| Vaxcyte, Inc.(PCVX) | 450,000 | 0 | -450,000 | $20.76M | $0 | — | -$20.76M |
| Voyager Therapeutics, Inc.(VYGR) | 4,002,847 | 0 | -4,002,847 | $15.73M | $0 | — | -$15.73M |