Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q1 2024 ▲▼ | Q2 2024 ▲▼ | Change ▲▼ | Q1 2024 ▲▼ | Q2 2024 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| MORPHIC HLDG INC | 2,384,384 | 4,982,945 | +2,598,561 | 83,930 | 169,769 | 5.19% | +85,839 |
| JANUX THERAPEUTICS INC(JANX) | 0 | 1,469,818 | +1,469,818 | 0 | 61,571 | 1.88% | +61,571 |
| CARGO THERAPEUTICS INC | 0 | 1,470,000 | +1,470,000 | 0 | 24,137 | 0.74% | +24,137 |
| ITEOS THERAPEUTICS INC | 1,999,249 | 3,249,835 | +1,250,586 | 27,270 | 48,228 | 1.48% | +20,958 |
| ANAPTYSBIO INC | 7,521,024 | 7,521,024 | 0 | 169,373 | 188,477 | 5.77% | +19,103 |
| BICYCLE THERAPEUTICS PLC | 0 | 910,000 | +910,000 | 0 | 18,418 | 0.56% | +18,418 |
| TECTONIC THERAPEUTIC INC(TECX) | 0 | 849,143 | +849,143 | 0 | 13,985 | 0.43% | +13,985 |
| AVIDITY BIOSCIENCES INC | 757,576 | 757,576 | 0 | 19,333 | 30,947 | 0.95% | +11,614 |
| THIRD HARMONIC BIO INC | 3,182,444 | 3,182,444 | 0 | 30,042 | 41,372 | 1.27% | +11,330 |
| ROCKET PHARMACEUTICALS INC(RCKT) | 0 | 508,393 | +508,393 | 0 | 10,946 | 0.33% | +10,946 |
| TANGO THERAPEUTICS INC(TNGX) | 13,330,736 | 13,330,736 | 0 | 105,846 | 114,378 | 3.50% | +8,532 |
| REPLIMUNE GROUP INC(REPL) | 0 | 850,341 | +850,341 | 0 | 7,653 | 0.23% | +7,653 |
| ATARA BIOTHERAPEUTICS INC | 0 | 406,679 | +406,679 | 0 | 3,457 | 0.11% | +3,457 |
| DYNE THERAPEUTICS INC(DYN) | 427,039 | 427,039 | 0 | 12,124 | 15,070 | 0.46% | +2,947 |
| VAXCYTE INC(PCVX) | 300,000 | 300,000 | 0 | 20,493 | 22,653 | 0.69% | +2,160 |
| MADRIGAL PHARMACEUTICALS INC(MDGL) | 75,000 | 75,000 | 0 | 20,028 | 21,012 | 0.64% | +984 |
| HOOKIPA PHARMA INC | 4,595,024 | 5,717,324 | +1,122,300 | 3,272 | 3,384 | 0.10% | +112 |
| ALPINE IMMUNE SCIENCES INC | 1,000 | 0 | -1,000 | 40 | 0 | — | -40 |
| CAREMAX INC | 100,000 | 100,000 | 0 | 482 | 279 | 0.01% | -203 |
| EDGEWISE THERAPEUTICS INC(EWTX) | 1,250,385 | 1,250,385 | 0 | 22,807 | 22,519 | 0.69% | -288 |
| SURROZEN INC(SRZN) | 66,665 | 66,665 | 0 | 1,047 | 730 | 0.02% | -317 |
| ALLOVIR INC | 11,294,585 | 11,294,585 | 0 | 8,526 | 8,169 | 0.25% | -357 |
| NUVATION BIO INC(NUVB) | 963,333 | 963,333 | 0 | 3,507 | 2,813 | 0.09% | -694 |
| PMV PHARMACEUTICALS INC(PMVP) | 566,879 | 0 | -566,879 | 964 | 0 | — | -964 |
| PRIME MEDICINE INC(PRME) | 700,000 | 700,000 | 0 | 4,900 | 3,598 | 0.11% | -1,302 |
| GENERATION BIO CO | 2,046,867 | 2,046,867 | 0 | 8,331 | 5,772 | 0.18% | -2,559 |
| PROQR THRAPEUTICS N V SHS EURO | 2,884,357 | 2,042,771 | -841,586 | 6,605 | 3,391 | 0.10% | -3,214 |
| CELLDEX THERAPEUTICS INC(CLDX) | 650,000 | 650,000 | 0 | 27,281 | 24,057 | 0.74% | -3,224 |
| KEROS THERAPEUTICS INC(KROS) | 187,500 | 187,500 | 0 | 12,413 | 8,569 | 0.26% | -3,844 |
| PHARVARIS N V COM | 900,000 | 900,000 | 0 | 20,799 | 16,920 | 0.52% | -3,879 |
| ALIGOS THERAPEUTICS INC | 6,389,468 | 6,389,468 | 0 | 6,262 | 2,236 | 0.07% | -4,025 |
| KURA ONCOLOGY INC(KURA) | 5,806,871 | 5,806,871 | 0 | 123,861 | 119,563 | 3.66% | -4,297 |
| ARCUTIS BIOTHERAPEUTICS INC(ARQT) | 500,000 | 0 | -500,000 | 4,955 | 0 | — | -4,955 |
| VOYAGER THERAPEUTICS INC(VYGR) | 3,917,546 | 3,917,546 | 0 | 36,472 | 30,988 | 0.95% | -5,485 |
| LENZ THERAPEUTICS INC(LENZ) | 1,219,774 | 1,219,774 | 0 | 27,238 | 21,090 | 0.65% | -6,148 |
| ATEA PHARMACEUTICALS INC(AVIR) | 6,145,861 | 5,441,896 | -703,965 | 24,829 | 18,013 | 0.55% | -6,817 |
| ATARA BIOTHERAPEUTICS INC | 10,167,043 | 0 | -10,167,043 | 7,056 | 0 | — | -7,056 |
| KYVERNA THERAPEUTICS INC(KYTX) | 450,000 | 450,000 | 0 | 11,178 | 3,375 | 0.10% | -7,803 |
| NEUMORA THERAPEUTICS INC.(NMRA) | 2,071,450 | 2,071,450 | 0 | 28,482 | 20,362 | 0.62% | -8,120 |
| CRINETICS PHARMACEUTICALS IN(CRNX) | 4,155,375 | 4,155,375 | 0 | 194,513 | 186,119 | 5.69% | -8,394 |
| KODIAK SCIENCES INC(KOD) | 1,613,600 | 0 | -1,613,600 | 8,488 | 0 | — | -8,488 |
| TSCAN THERAPEUTICS INC(TCRX) | 5,000,000 | 5,000,000 | 0 | 39,700 | 29,250 | 0.89% | -10,450 |
| VERVE THERAPEUTICS INC | 1,250,000 | 1,250,000 | 0 | 16,600 | 6,100 | 0.19% | -10,500 |
| GOSSAMER BIO INC(GOSS) | 9,195,404 | 0 | -9,195,404 | 10,851 | 0 | — | -10,851 |
| CENTESSA PHARMACEUTICALS PLC | 5,618,779 | 5,714,404 | +95,625 | 63,492 | 51,601 | 1.58% | -11,891 |
| NUVATION BIO INC(NUVB) | 19,209,643 | 19,209,643 | 0 | 69,923 | 56,092 | 1.72% | -13,831 |
| JAZZ PHARMACEUTICALS PLC(JAZZ) | 1,013,952 | 1,013,952 | 0 | 122,100 | 108,219 | 3.31% | -13,881 |
| ADAPTIMMUNE THERAPEUTICS PLC(ADAPY) | 27,404,070 | 27,404,070 | 0 | 43,298 | 26,716 | 0.82% | -16,582 |
| XENCOR INC(XNCR) | 5,330,416 | 5,330,416 | 0 | 117,962 | 100,905 | 3.09% | -17,057 |
| NEUROGENE INC(NGNE) | 1,271,342 | 1,271,342 | 0 | 64,711 | 46,264 | 1.42% | -18,447 |
| OVID THERAPEUTICS INC(OVID) | 6,117,400 | 0 | -6,117,400 | 18,658 | 0 | — | -18,658 |
| CRISPR THERAPEUTICS AG(CRSP) | 1,389,276 | 1,389,276 | 0 | 94,693 | 75,035 | 2.30% | -19,658 |
| NKARTA INC(NKTX) | 2,000,000 | 0 | -2,000,000 | 21,620 | 0 | — | -21,620 |
| ORIC PHARMACEUTICALS INC(ORIC) | 3,418,068 | 3,418,068 | 0 | 46,998 | 24,166 | 0.74% | -22,833 |
| ALECTOR INC | 4,056,548 | 0 | -4,056,548 | 24,420 | 0 | — | -24,420 |
| SAREPTA THERAPEUTICS INC(SRPT) | 1,919,835 | 1,407,322 | -512,513 | 248,542 | 222,357 | 6.80% | -26,185 |
| ZYMEWORKS INC(ZYME) | 13,437,473 | 13,437,473 | 0 | 141,362 | 114,353 | 3.50% | -27,009 |
| GALAPAGOS NV(LKFT) | 5,756,268 | 5,756,268 | 0 | 185,352 | 142,640 | 4.36% | -42,712 |
| MERSANA THERAPEUTICS INC | 19,364,688 | 19,364,688 | 0 | 86,754 | 38,923 | 1.19% | -47,831 |
| PROTHENA CORP PLC SHS | 11,584,280 | 11,584,280 | 0 | 286,943 | 239,100 | 7.31% | -47,843 |
| IMMUNOME INC(IMNM) | 3,879,415 | 3,879,415 | 0 | 95,744 | 46,941 | 1.44% | -48,803 |
| ACADIA PHARMACEUTICALS INC | 5,991,479 | 1,346,475 | -4,645,004 | 110,782 | 21,880 | 0.67% | -88,902 |
| ARVINAS INC(ARVN) | 6,726,491 | 6,726,491 | 0 | 277,670 | 179,059 | 5.48% | -98,610 |
| APELLIS PHARMACEUTICALS INC COM | 11,357,425 | 11,607,425 | +250,000 | 667,589 | 445,261 | 13.62% | -222,329 |