Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q2 2024 ▲▼ | Q3 2024 ▲▼ | Change ▲▼ | Q2 2024 ▲▼ | Q3 2024 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| JAZZ PHARMACEUTICALS PLC(JAZZ) | 1,013,952 | 1,706,469 | +692,517 | 108,219 | 190,118 | 6.51% | +81,899 |
| ANAPTYSBIO INC | 7,521,024 | 7,794,996 | +273,972 | 188,477 | 261,132 | 8.94% | +72,656 |
| ZYMEWORKS INC(ZYME) | 13,437,473 | 13,437,473 | 0 | 114,353 | 168,640 | 5.77% | +54,287 |
| VIRIDIAN THERAPEUTICS INC(VRDN) | 0 | 1,958,847 | +1,958,847 | 0 | 44,564 | 1.53% | +44,564 |
| CRINETICS PHARMACEUTICALS IN(CRNX) | 4,155,375 | 4,288,120 | +132,745 | 186,119 | 219,123 | 7.50% | +33,004 |
| MBX BIOSCIENCES INC(MBX) | 0 | 1,175,809 | +1,175,809 | 0 | 30,548 | 1.05% | +30,548 |
| IONIS PHARMACEUTICALS INC(IONS) | 0 | 500,000 | +500,000 | 0 | 20,030 | 0.69% | +20,030 |
| RELAY THERAPEUTICS INC(RLAY) | 0 | 2,500,000 | +2,500,000 | 0 | 17,700 | 0.61% | +17,700 |
| VAXCYTE INC(PCVX) | 300,000 | 352,464 | +52,464 | 22,653 | 40,276 | 1.38% | +17,623 |
| DAY ONE BIOPHARMACEUTICALS I COM | 0 | 862,068 | +862,068 | 0 | 12,009 | 0.41% | +12,009 |
| TECTONIC THERAPEUTIC INC(TECX) | 849,143 | 849,143 | 0 | 13,985 | 25,729 | 0.88% | +11,744 |
| ORIC PHARMACEUTICALS INC(ORIC) | 3,418,068 | 3,418,068 | 0 | 24,166 | 35,035 | 1.20% | +10,869 |
| EDGEWISE THERAPEUTICS INC(EWTX) | 1,250,385 | 1,250,385 | 0 | 22,519 | 33,373 | 1.14% | +10,853 |
| IMMUNOME INC(IMNM) | 3,879,415 | 3,879,415 | 0 | 46,941 | 56,717 | 1.94% | +9,776 |
| NEUROGENE INC(NGNE) | 1,271,342 | 1,271,342 | 0 | 46,264 | 53,346 | 1.83% | +7,081 |
| NEUMORA THERAPEUTICS INC.(NMRA) | 2,071,450 | 2,071,450 | 0 | 20,362 | 27,364 | 0.94% | +7,002 |
| XENCOR INC(XNCR) | 5,330,416 | 5,330,416 | 0 | 100,905 | 107,195 | 3.67% | +6,290 |
| JANUX THERAPEUTICS INC(JANX) | 1,469,818 | 1,469,818 | 0 | 61,571 | 66,774 | 2.29% | +5,203 |
| DYNE THERAPEUTICS INC(DYN) | 427,039 | 555,644 | +128,605 | 15,070 | 19,959 | 0.68% | +4,889 |
| BRIDGEBIO PHARMA INC(BBIO) | 0 | 170,172 | +170,172 | 0 | 4,333 | 0.15% | +4,333 |
| AVIDITY BIOSCIENCES INC | 757,576 | 757,576 | 0 | 30,947 | 34,795 | 1.19% | +3,848 |
| AADI BIOSCIENCE INC(WHWK) | 0 | 1,845,253 | +1,845,253 | 0 | 3,801 | 0.13% | +3,801 |
| ETON PHARMACEUTICALS INC(ETON) | 0 | 566,075 | +566,075 | 0 | 3,396 | 0.12% | +3,396 |
| CARGO THERAPEUTICS INC | 1,470,000 | 1,470,000 | 0 | 24,137 | 27,122 | 0.93% | +2,984 |
| HOOKIPA PHARMA INC | 0 | 571,727 | +571,727 | 0 | 2,458 | 0.08% | +2,458 |
| KEROS THERAPEUTICS INC(KROS) | 187,500 | 187,500 | 0 | 8,569 | 10,888 | 0.37% | +2,319 |
| ALIGOS THERAPEUTICS INC(ALGS) | 0 | 255,573 | +255,573 | 0 | 2,213 | 0.08% | +2,213 |
| BICYCLE THERAPEUTICS PLC | 910,000 | 910,000 | 0 | 18,418 | 20,593 | 0.71% | +2,175 |
| THIRD HARMONIC BIO INC | 3,182,444 | 3,182,444 | 0 | 41,372 | 43,122 | 1.48% | +1,750 |
| REPLIMUNE GROUP INC(REPL) | 850,341 | 850,341 | 0 | 7,653 | 9,320 | 0.32% | +1,667 |
| ALLOVIR INC | 11,294,585 | 11,294,585 | 0 | 8,169 | 9,132 | 0.31% | +962 |
| ARTIVA BIOTHERAPEUTICS INC(ARTV) | 0 | 41,453 | +41,453 | 0 | 640 | 0.02% | +640 |
| ATARA BIOTHERAPEUTICS INC | 406,679 | 468,938 | +62,259 | 3,457 | 3,812 | 0.13% | +356 |
| DESIGN THERAPEUTICS INC(DSGN) | 0 | 53,834 | +53,834 | 0 | 290 | 0.01% | +290 |
| ATEA PHARMACEUTICALS INC(AVIR) | 5,441,896 | 5,441,896 | 0 | 18,013 | 18,230 | 0.62% | +218 |
| MACROGENICS INC(MGNX) | 0 | 56,018 | +56,018 | 0 | 184 | 0.01% | +184 |
| ALLAKOS INC | 0 | 192,346 | +192,346 | 0 | 126 | 0.00% | +126 |
| SURROZEN INC(SRZN) | 66,665 | 66,665 | 0 | 730 | 799 | 0.03% | +69 |
| PROQR THRAPEUTICS N V SHS EURO | 2,042,771 | 1,835,991 | -206,780 | 3,391 | 3,342 | 0.11% | -49 |
| VERVE THERAPEUTICS INC | 1,250,000 | 1,250,000 | 0 | 6,100 | 6,050 | 0.21% | -50 |
| CENTESSA PHARMACEUTICALS PLC | 5,714,404 | 3,223,851 | -2,490,553 | 51,601 | 51,549 | 1.77% | -52 |
| CAREMAX INC | 100,000 | 100,000 | 0 | 279 | 170 | 0.01% | -109 |
| PHARVARIS N V COM | 900,000 | 900,000 | 0 | 16,920 | 16,668 | 0.57% | -252 |
| NUVATION BIO INC(NUVB) | 963,333 | 963,333 | 0 | 2,813 | 2,206 | 0.08% | -607 |
| ADAPTIMMUNE THERAPEUTICS PLC(ADAPY) | 27,404,070 | 27,404,070 | 0 | 26,716 | 26,045 | 0.89% | -671 |
| GENERATION BIO CO | 2,046,867 | 2,046,867 | 0 | 5,772 | 5,056 | 0.17% | -716 |
| PRIME MEDICINE INC(PRME) | 700,000 | 700,000 | 0 | 3,598 | 2,709 | 0.09% | -889 |
| KYVERNA THERAPEUTICS INC(KYTX) | 450,000 | 450,000 | 0 | 3,375 | 2,201 | 0.08% | -1,174 |
| CELLDEX THERAPEUTICS INC NEW(CLDX) | 650,000 | 650,000 | 0 | 24,057 | 22,094 | 0.76% | -1,963 |
| ALIGOS THERAPEUTICS INC | 6,389,468 | 0 | -6,389,468 | 2,236 | 0 | — | -2,236 |
| MERSANA THERAPEUTICS INC | 19,364,688 | 19,364,688 | 0 | 38,923 | 36,599 | 1.25% | -2,324 |
| HOOKIPA PHARMA INC | 5,717,324 | 0 | -5,717,324 | 3,384 | 0 | — | -3,384 |
| TSCAN THERAPEUTICS INC(TCRX) | 5,000,000 | 5,000,000 | 0 | 29,250 | 24,900 | 0.85% | -4,350 |
| MADRIGAL PHARMACEUTICALS INC(MDGL) | 75,000 | 75,000 | 0 | 21,012 | 15,917 | 0.55% | -5,095 |
| KURA ONCOLOGY INC(KURA) | 5,806,871 | 5,806,871 | 0 | 119,563 | 113,466 | 3.89% | -6,097 |
| VOYAGER THERAPEUTICS INC(VYGR) | 3,917,546 | 3,917,546 | 0 | 30,988 | 22,918 | 0.78% | -8,070 |
| CRISPR THERAPEUTICS AG(CRSP) | 1,389,276 | 1,389,276 | 0 | 75,035 | 65,268 | 2.24% | -9,767 |
| ROCKET PHARMACEUTICALS INC(RCKT) | 508,393 | 0 | -508,393 | 10,946 | 0 | — | -10,946 |
| TANGO THERAPEUTICS INC(TNGX) | 13,330,736 | 13,330,736 | 0 | 114,378 | 102,647 | 3.52% | -11,731 |
| NUVATION BIO INC(NUVB) | 19,209,643 | 19,209,643 | 0 | 56,092 | 43,990 | 1.51% | -12,102 |
| LENZ THERAPEUTICS INC(LENZ) | 1,219,774 | 346,772 | -873,002 | 21,090 | 8,232 | 0.28% | -12,858 |
| ARVINAS INC(ARVN) | 6,726,491 | 6,726,491 | 0 | 179,059 | 165,673 | 5.67% | -13,386 |
| ACADIA PHARMACEUTICALS INC | 1,346,475 | 0 | -1,346,475 | 21,880 | 0 | — | -21,880 |
| ITEOS THERAPEUTICS INC | 3,249,835 | 1,608,616 | -1,641,219 | 48,228 | 16,424 | 0.56% | -31,804 |
| PROTHENA CORP PLC SHS | 11,584,280 | 11,584,280 | 0 | 239,100 | 193,805 | 6.64% | -45,295 |
| APELLIS PHARMACEUTICALS INC COM | 11,607,425 | 11,890,843 | +283,418 | 445,261 | 342,932 | 11.74% | -102,329 |
| GALAPAGOS NV(LKFT) | 5,756,268 | 155,006 | -5,601,262 | 142,640 | 4,463 | 0.15% | -138,178 |
| MORPHIC HLDG INC | 4,982,945 | 0 | -4,982,945 | 169,769 | 0 | — | -169,769 |
| SAREPTA THERAPEUTICS INC(SRPT) | 1,407,322 | 0 | -1,407,322 | 222,357 | 0 | — | -222,357 |