Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q2 2025 ▲▼ | Q3 2025 ▲▼ | Change ▲▼ | Q2 2025 ▲▼ | Q3 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Zymeworks Inc.(ZYME) | 22,970,388 | 22,970,388 | 0 | $288.28M | $392.33M | 18.83% | +$104.06M |
| Anaptysbio Inc | 7,880,094 | 7,880,094 | 0 | $174.94M | $241.29M | 11.58% | +$66.35M |
| uniQure N.V.SHS(QURE) | 3,988,971 | 3,988,971 | 0 | $55.61M | $232.84M | 11.17% | +$177.23M |
| Jazz Pharmaceuticals plcSHS USD(JAZZ) | 1,706,469 | 1,706,469 | 0 | $181.09M | $224.91M | 10.79% | +$43.82M |
| Crinetics Pharmaceuticals In | 4,288,120 | 4,288,120 | 0 | $123.33M | $178.60M | 8.57% | +$55.27M |
| CRISPR Therapeutics AGNAMEN AKT(CRSP) | 1,389,276 | 1,389,276 | 0 | $67.57M | $90.04M | 4.32% | +$22.46M |
| Tango Therapeutics, Inc.(TNGX) | 10,630,736 | 10,630,736 | 0 | $54.43M | $89.30M | 4.29% | +$34.87M |
| ORIC Pharmaceuticals, Inc.(ORIC) | 1,618,068 | 6,728,116 | +5,110,048 | $16.42M | $80.74M | 3.87% | +$64.31M |
| Apellis Pharmaceuticals Inc COM | 11,895,808 | 3,447,156 | -8,448,652 | $205.92M | $78.01M | 3.74% | -$127.91M |
| Xencor, Inc.(XNCR) | 6,144,767 | 6,144,767 | 0 | $48.30M | $72.08M | 3.46% | +$23.78M |
| Lakefront Biotherapeutics NVADR(LKFT) | 1,036,945 | 1,667,119 | +630,174 | $29.02M | $57.75M | 2.77% | +$28.72M |
| Immunome, Inc.(IMNM) | 4,079,415 | 4,079,415 | 0 | $37.94M | $47.77M | 2.29% | +$9.83M |
| Eton Pharmaceuticals, Inc.(ETON) | 2,030,544 | 2,030,544 | 0 | $28.94M | $44.12M | 2.12% | +$15.19M |
| MBX Biosciences, Inc.(MBX) | 1,149,794 | 2,123,604 | +973,810 | $13.12M | $37.16M | 1.78% | +$24.04M |
| Madrigal Pharmaceuticals, Inc.(MDGL) | 75,000 | 75,000 | 0 | $22.70M | $34.40M | 1.65% | +$11.70M |
| Avidity Biosciences Inc | 500,000 | 765,000 | +265,000 | $14.20M | $33.33M | 1.60% | +$19.13M |
| BridgeBio Oncology Therapeutics, Inc.COM NEW ADDED(BBOT) | 0 | 2,823,126 | +2,823,126 | $0 | $32.69M | 1.57% | +$32.69M |
| Neurogene Inc.(NGNE) | 1,271,342 | 1,271,342 | 0 | $19.01M | $22.03M | 1.06% | +$3.03M |
| Alkermes plcSHS(ALKS) | 500,000 | 500,000 | 0 | $14.30M | $15.00M | 0.72% | +$695.0K |
| Aquestive Therapeutics Inc | 0 | 2,625,000 | +2,625,000 | $0 | $14.67M | 0.70% | +$14.67M |
| Metsera Inc | 271,529 | 271,529 | 0 | $7.72M | $14.21M | 0.68% | +$6.48M |
| Centessa Pharmaceuticals PlcADS | 0 | 550,000 | +550,000 | $0 | $13.34M | 0.64% | +$13.34M |
| Prime Medicine, Inc.(PRME) | 0 | 1,543,326 | +1,543,326 | $0 | $8.55M | 0.41% | +$8.55M |
| Atara Biotherapeutics Inc | 573,183 | 573,183 | 0 | $4.42M | $8.21M | 0.39% | +$3.79M |
| Kura Oncology, Inc.(KURA) | 4,200,000 | 872,500 | -3,327,500 | $24.23M | $7.72M | 0.37% | -$16.51M |
| PepGen Inc.(PEPG) | 0 | 800,000 | +800,000 | $0 | $3.70M | 0.18% | +$3.70M |
| Nuvation Bio Inc.W EXP 02 10 202(NUVB) | 963,333 | 963,333 | 0 | $1.88M | $3.56M | 0.17% | +$1.69M |
| Voyager Therapeutics, Inc.(VYGR) | 3,917,546 | 670,303 | -3,247,243 | $12.18M | $3.13M | 0.15% | -$9.05M |
| COMPASS Pathways plcADS(CMPS) | 0 | 265,137 | +265,137 | $0 | $1.52M | 0.07% | +$1.52M |
| Surrozen, Inc.W EXP 08 01 203(SRZN) | 66,665 | 66,665 | 0 | $596.0K | $859.3K | 0.04% | +$263.3K |
| Adaptimmune Therapeutics plcADS(ADAPY) | 27,404,070 | 0 | -27,404,070 | $6.57M | $0 | — | -$6.57M |
| Akero Therapeutics Inc | 440,000 | 0 | -440,000 | $23.48M | $0 | — | -$23.48M |
| Day One Biopharmaceuticals I COM | 862,068 | 0 | -862,068 | $5.60M | $0 | — | -$5.60M |
| Hillevax Inc | 2,420,243 | 0 | -2,420,243 | $4.82M | $0 | — | -$4.82M |
| Iteos Therapeutics Inc | 10,688,978 | 0 | -10,688,978 | $106.57M | $0 | — | -$106.57M |
| Janux Therapeutics, Inc.(JANX) | 1,469,818 | 0 | -1,469,818 | $33.95M | $0 | — | -$33.95M |
| MacroGenics, Inc.(MGNX) | 1,602,717 | 0 | -1,602,717 | $1.94M | $0 | — | -$1.94M |
| Pacira BioSciences, Inc.(PCRX) | 457,471 | 0 | -457,471 | $10.93M | $0 | — | -$10.93M |
| Replimune Group, Inc.(REPL) | 850,341 | 0 | -850,341 | $7.90M | $0 | — | -$7.90M |
| Tectonic Therapeutic, Inc.(TECX) | 935,121 | 0 | -935,121 | $18.58M | $0 | — | -$18.58M |
| Verona Pharma PlcADS | 200,000 | 0 | -200,000 | $18.92M | $0 | — | -$18.92M |
| Whitehawk Therapeutics, Inc.(WHWK) | 1,091,417 | 0 | -1,091,417 | $2.04M | $0 | — | -$2.04M |