Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q3 2024 ▲▼ | Q4 2024 ▲▼ | Change ▲▼ | Q3 2024 ▲▼ | Q4 2024 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Apellis Pharmaceuticals Inc COM | 11,890,843 | 11,890,843 | 0 | $342.93M | $379.44M | 15.16% | +$36.50M |
| Zymeworks Inc.(ZYME) | 13,437,473 | 15,028,079 | +1,590,606 | $168.64M | $220.01M | 8.79% | +$51.37M |
| Crinetics Pharmaceuticals In | 4,288,120 | 4,288,120 | 0 | $219.12M | $219.25M | 8.76% | +$128.6K |
| Jazz Pharmaceuticals plcSHS USD(JAZZ) | 1,706,469 | 1,706,469 | 0 | $190.12M | $210.15M | 8.39% | +$20.03M |
| Prothena Corp PlcSHS SHS | 11,584,280 | 11,584,280 | 0 | $193.81M | $160.44M | 6.41% | -$33.36M |
| Xencor, Inc.(XNCR) | 5,330,416 | 6,144,767 | +814,351 | $107.19M | $141.21M | 5.64% | +$34.01M |
| Arvinas, Inc.(ARVN) | 6,726,491 | 6,726,491 | 0 | $165.67M | $128.95M | 5.15% | -$36.73M |
| Anaptysbio Inc | 7,794,996 | 7,873,448 | +78,452 | $261.13M | $104.24M | 4.16% | -$156.89M |
| Sarepta Therapeutics, Inc.(SRPT) | 0 | 770,000 | +770,000 | $0 | $93.62M | 3.74% | +$93.62M |
| Janux Therapeutics, Inc.(JANX) | 1,469,818 | 1,469,818 | 0 | $66.77M | $78.69M | 3.14% | +$11.92M |
| uniQure N.V.SHS(QURE) | 0 | 3,400,000 | +3,400,000 | $0 | $60.04M | 2.40% | +$60.04M |
| Springworks Therapeutics Inc | 0 | 1,560,000 | +1,560,000 | $0 | $56.36M | 2.25% | +$56.36M |
| CRISPR Therapeutics AGNAMEN AKT(CRSP) | 1,389,276 | 1,389,276 | 0 | $65.27M | $54.68M | 2.18% | -$10.59M |
| Immunome, Inc.(IMNM) | 3,879,415 | 3,879,415 | 0 | $56.72M | $41.20M | 1.65% | -$15.52M |
| Tectonic Therapeutic, Inc.(TECX) | 849,143 | 849,143 | 0 | $25.73M | $39.20M | 1.57% | +$13.48M |
| Tango Therapeutics, Inc.(TNGX) | 13,330,736 | 10,630,736 | -2,700,000 | $102.65M | $32.85M | 1.31% | -$69.80M |
| Third Harmonic Bio Inc | 3,182,444 | 3,182,444 | 0 | $43.12M | $32.75M | 1.31% | -$10.37M |
| Kura Oncology, Inc.(KURA) | 5,806,871 | 3,557,269 | -2,249,602 | $113.47M | $30.98M | 1.24% | -$82.48M |
| Neurogene Inc.(NGNE) | 1,271,342 | 1,271,342 | 0 | $53.35M | $29.06M | 1.16% | -$24.28M |
| ORIC Pharmaceuticals, Inc.(ORIC) | 3,418,068 | 3,418,068 | 0 | $35.04M | $27.58M | 1.10% | -$7.45M |
| Eton Pharmaceuticals, Inc.(ETON) | 566,075 | 1,829,603 | +1,263,528 | $3.40M | $24.37M | 0.97% | +$20.97M |
| MBX Biosciences, Inc.(MBX) | 1,175,809 | 1,259,273 | +83,464 | $30.55M | $23.21M | 0.93% | -$7.34M |
| Madrigal Pharmaceuticals, Inc.(MDGL) | 75,000 | 75,000 | 0 | $15.92M | $23.14M | 0.92% | +$7.23M |
| Voyager Therapeutics, Inc.(VYGR) | 3,917,546 | 3,917,546 | 0 | $22.92M | $22.21M | 0.89% | -$705.2K |
| Neumora Therapeutics, Inc.(NMRA) | 2,071,450 | 2,071,450 | 0 | $27.36M | $21.96M | 0.88% | -$5.41M |
| Cargo Therapeutics Inc | 1,470,000 | 1,470,000 | 0 | $27.12M | $21.20M | 0.85% | -$5.92M |
| MoonLake ImmunotherapeuticsCL A(MLTX) | 0 | 332,522 | +332,522 | $0 | $18.01M | 0.72% | +$18.01M |
| Ginkgo Bioworks Holdings, Inc.CL A(DNA) | 0 | 1,743,344 | +1,743,344 | $0 | $17.12M | 0.68% | +$17.12M |
| Avidity Biosciences Inc | 757,576 | 557,576 | -200,000 | $34.80M | $16.21M | 0.65% | -$18.58M |
| Mersana Therapeutics Inc | 19,364,688 | 11,328,000 | -8,036,688 | $36.60M | $16.20M | 0.65% | -$20.40M |
| TScan Therapeutics, Inc.(TCRX) | 5,000,000 | 5,000,000 | 0 | $24.90M | $15.20M | 0.61% | -$9.70M |
| Adaptimmune Therapeutics plcADR(ADAPY) | 27,404,070 | 27,404,070 | 0 | $26.04M | $14.76M | 0.59% | -$11.28M |
| Kymera Therapeutics, Inc.(KYMR) | 0 | 350,000 | +350,000 | $0 | $14.08M | 0.56% | +$14.08M |
| Dyne Therapeutics, Inc.(DYN) | 555,644 | 555,644 | 0 | $19.96M | $13.09M | 0.52% | -$6.87M |
| Bicycle Therapeutics PlcADS | 910,000 | 910,000 | 0 | $20.59M | $12.74M | 0.51% | -$7.85M |
| Atea Pharmaceuticals, Inc.(AVIR) | 5,441,896 | 3,341,653 | -2,100,243 | $18.23M | $11.19M | 0.45% | -$7.04M |
| Day One Biopharmaceuticals I COM | 862,068 | 862,068 | 0 | $12.01M | $10.92M | 0.44% | -$1.09M |
| Replimune Group, Inc.(REPL) | 850,341 | 850,341 | 0 | $9.32M | $10.30M | 0.41% | +$977.9K |
| Aligos Therapeutics, Inc.(ALGS) | 255,573 | 255,573 | 0 | $2.21M | $10.18M | 0.41% | +$7.97M |
| Atara Biotherapeutics Inc | 468,938 | 532,134 | +63,196 | $3.81M | $7.08M | 0.28% | +$3.27M |
| Verve Therapeutics Inc | 1,250,000 | 1,250,000 | 0 | $6.05M | $7.05M | 0.28% | +$1.00M |
| Fate Therapeutics, Inc.(FATE) | 0 | 3,049,405 | +3,049,405 | $0 | $5.03M | 0.20% | +$5.03M |
| Lakefront Biotherapeutics NVADR(LKFT) | 155,006 | 155,006 | 0 | $4.46M | $4.26M | 0.17% | -$200.0K |
| Allovir Inc | 11,294,585 | 408,688 | -10,885,897 | $9.13M | $3.95M | 0.16% | -$5.18M |
| Keros Therapeutics, Inc.(KROS) | 187,500 | 187,500 | 0 | $10.89M | $2.97M | 0.12% | -$7.92M |
| Relay Therapeutics, Inc.(RLAY) | 2,500,000 | 641,426 | -1,858,574 | $17.70M | $2.64M | 0.11% | -$15.06M |
| Design Therapeutics, Inc.(DSGN) | 53,834 | 426,683 | +372,849 | $289.6K | $2.63M | 0.11% | +$2.34M |
| Nuvation Bio Inc.W EXP 02 10 202(NUVB) | 963,333 | 963,333 | 0 | $2.21M | $2.56M | 0.10% | +$356.4K |
| Generation Bio Co | 2,046,867 | 2,046,867 | 0 | $5.06M | $2.17M | 0.09% | -$2.89M |
| Prime Medicine, Inc.(PRME) | 700,000 | 700,000 | 0 | $2.71M | $2.04M | 0.08% | -$665.0K |
| Whitehawk Therapeutics, Inc.(WHWK) | 1,845,253 | 345,253 | -1,500,000 | $3.80M | $1.09M | 0.04% | -$2.71M |
| Upstream Bio, Inc.(UPB) | 0 | 60,000 | +60,000 | $0 | $986.4K | 0.04% | +$986.4K |
| Surrozen, Inc.W EXP 08 01 203(SRZN) | 66,665 | 66,665 | 0 | $798.6K | $956.6K | 0.04% | +$158.0K |
| Hookipa Pharma Inc | 571,727 | 388,861 | -182,866 | $2.46M | $781.6K | 0.03% | -$1.68M |
| Artiva Biotherapeutics, Inc.(ARTV) | 41,453 | 41,453 | 0 | $640.4K | $417.8K | 0.02% | -$222.6K |
| Allakos Inc | 192,346 | 0 | -192,346 | $125.6K | $0 | — | -$125.6K |
| BridgeBio Pharma, Inc.(BBIO) | 170,172 | 0 | -170,172 | $4.33M | $0 | — | -$4.33M |
| Caremax IncW EXP 06 08 202 | 100,000 | 0 | -100,000 | $170.0K | $0 | — | -$170.0K |
| Celldex Therapeutics, Inc.(CLDX) | 650,000 | 0 | -650,000 | $22.09M | $0 | — | -$22.09M |
| Centessa Pharmaceuticals PlcADS | 3,223,851 | 0 | -3,223,851 | $51.55M | $0 | — | -$51.55M |
| Edgewise Therapeutics, Inc.(EWTX) | 1,250,385 | 0 | -1,250,385 | $33.37M | $0 | — | -$33.37M |
| Ionis Pharmaceuticals, Inc.(IONS) | 500,000 | 0 | -500,000 | $20.03M | $0 | — | -$20.03M |
| Iteos Therapeutics Inc | 1,608,616 | 0 | -1,608,616 | $16.42M | $0 | — | -$16.42M |
| Kyverna Therapeutics, Inc.(KYTX) | 450,000 | 0 | -450,000 | $2.20M | $0 | — | -$2.20M |
| LENZ Therapeutics, Inc.(LENZ) | 346,772 | 0 | -346,772 | $8.23M | $0 | — | -$8.23M |
| MacroGenics, Inc.(MGNX) | 56,018 | 0 | -56,018 | $184.3K | $0 | — | -$184.3K |
| Nuvation Bio Inc.CL A(NUVB) | 19,209,643 | 0 | -19,209,643 | $43.99M | $0 | — | -$43.99M |
| Pharvaris N V COM | 900,000 | 0 | -900,000 | $16.67M | $0 | — | -$16.67M |
| Proqr Thrapeutics N VSHS EURO SHS EURO | 1,835,991 | 0 | -1,835,991 | $3.34M | $0 | — | -$3.34M |
| Vaxcyte, Inc.(PCVX) | 352,464 | 0 | -352,464 | $40.28M | $0 | — | -$40.28M |
| Viridian Therapeutics, Inc.(VRDN) | 1,958,847 | 0 | -1,958,847 | $44.56M | $0 | — | -$44.56M |