Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q3 2025 ▲▼ | Q4 2025 ▲▼ | Change ▲▼ | Q3 2025 ▲▼ | Q4 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| ZYMEWORKS INC(ZYME) | 22,970,388 | 22,970,388 | 0 | 392,334 | 604,810 | 27.61% | +212,476 |
| ANAPTYSBIO INC | 7,880,094 | 7,880,094 | 0 | 241,288 | 382,027 | 17.44% | +140,738 |
| JAZZ PHARMACEUTICALS PLC(JAZZ) | 1,706,469 | 1,706,469 | 0 | 224,913 | 290,100 | 13.24% | +65,187 |
| CENTESSA PHARMACEUTICALS PLC | 550,000 | 3,115,000 | +2,565,000 | 13,338 | 77,906 | 3.56% | +64,569 |
| CG ONCOLOGY INC(CGON) | 0 | 772,000 | +772,000 | 0 | 32,053 | 1.46% | +32,053 |
| MBX BIOSCIENCES INC(MBX) | 2,123,604 | 2,123,604 | 0 | 37,163 | 66,978 | 3.06% | +29,815 |
| ZENAS BIOPHARMA INC(ZBIO) | 0 | 789,500 | +789,500 | 0 | 28,667 | 1.31% | +28,667 |
| STRUCTURE THERAPEUTICS INC | 0 | 334,380 | +334,380 | 0 | 23,256 | 1.06% | +23,256 |
| CRINETICS PHARMACEUTICALS IN(CRNX) | 4,288,120 | 4,288,120 | 0 | 178,600 | 199,612 | 9.11% | +21,012 |
| VAXCYTE INC(PCVX) | 0 | 450,000 | +450,000 | 0 | 20,763 | 0.95% | +20,763 |
| IMMUNOME INC(IMNM) | 4,079,415 | 2,855,590 | -1,223,825 | 47,770 | 61,338 | 2.80% | +13,568 |
| VOYAGER THERAPEUTICS INC(VYGR) | 670,303 | 4,002,847 | +3,332,544 | 3,130 | 15,731 | 0.72% | +12,601 |
| MANNKIND CORP(MNKD) | 0 | 1,660,000 | +1,660,000 | 0 | 9,412 | 0.43% | +9,412 |
| NUVATION BIO INC(NUVB) | 963,333 | 963,333 | 0 | 3,564 | 8,631 | 0.39% | +5,067 |
| EVOLUS INC(EOLS) | 0 | 675,000 | +675,000 | 0 | 4,489 | 0.20% | +4,489 |
| IBIO INC(IBIO) | 0 | 2,228,000 | +2,228,000 | 0 | 4,300 | 0.20% | +4,300 |
| NEUROGENE INC(NGNE) | 1,271,342 | 1,271,342 | 0 | 22,032 | 26,190 | 1.20% | +4,157 |
| MEREO BIOPHARMA GROUP PLC(MREO) | 0 | 7,856,466 | +7,856,466 | 0 | 3,274 | 0.15% | +3,274 |
| BRIDGEBIO ONCOLOGY THERAPEUT(BBOT) | 2,823,126 | 2,823,126 | 0 | 32,692 | 35,346 | 1.61% | +2,654 |
| AQUESTIVE THERAPEUTICS INC | 2,625,000 | 2,625,000 | 0 | 14,674 | 16,958 | 0.77% | +2,284 |
| ATARA BIOTHERAPEUTICS INC | 573,183 | 573,183 | 0 | 8,214 | 10,369 | 0.47% | +2,155 |
| CAMP4 THERAPEUTICS CORP(CAMP) | 0 | 325,000 | +325,000 | 0 | 1,992 | 0.09% | +1,992 |
| SURROZEN INC(SRZN) | 66,665 | 4,444 | -62,221 | 859 | 100 | 0.00% | -759 |
| COMPASS PATHWAYS PLC(CMPS) | 265,137 | 0 | -265,137 | 1,519 | 0 | — | -1,519 |
| GALAPAGOS NV(LKFT) | 1,667,119 | 1,667,119 | 0 | 57,749 | 54,515 | 2.49% | -3,234 |
| PEPGEN INC(PEPG) | 800,000 | 0 | -800,000 | 3,696 | 0 | — | -3,696 |
| KURA ONCOLOGY INC(KURA) | 872,500 | 0 | -872,500 | 7,722 | 0 | — | -7,722 |
| PRIME MEDICINE INC(PRME) | 1,543,326 | 0 | -1,543,326 | 8,550 | 0 | — | -8,550 |
| ETON PHARMACEUTICALS INC(ETON) | 2,030,544 | 2,030,544 | 0 | 44,124 | 34,336 | 1.57% | -9,787 |
| METSERA INC | 271,529 | 0 | -271,529 | 14,209 | 0 | — | -14,209 |
| ALKERMES PLC(ALKS) | 500,000 | 0 | -500,000 | 15,000 | 0 | — | -15,000 |
| CRISPR THERAPEUTICS AG(CRSP) | 1,389,276 | 1,389,276 | 0 | 90,039 | 72,854 | 3.33% | -17,185 |
| XENCOR INC(XNCR) | 6,144,767 | 3,251,112 | -2,893,655 | 72,078 | 49,775 | 2.27% | -22,304 |
| ORIC PHARMACEUTICALS INC(ORIC) | 6,728,116 | 6,728,116 | 0 | 80,737 | 55,036 | 2.51% | -25,701 |
| AVIDITY BIOSCIENCES INC | 765,000 | 0 | -765,000 | 33,331 | 0 | — | -33,331 |
| MADRIGAL PHARMACEUTICALS INC(MDGL) | 75,000 | 0 | -75,000 | 34,400 | 0 | — | -34,399 |
| APELLIS PHARMACEUTICALS INC COM | 3,447,156 | 0 | -3,447,156 | 78,009 | 0 | — | -78,009 |
| TANGO THERAPEUTICS INC(TNGX) | 10,630,736 | 0 | -10,630,736 | 89,298 | 0 | — | -89,298 |
| UNIQURE NV(QURE) | 3,988,971 | 0 | -3,988,971 | 232,836 | 0 | — | -232,836 |