Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q3 2025 ▲▼ | Q4 2025 ▲▼ | Change ▲▼ | Q3 2025 ▲▼ | Q4 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Zymeworks Inc.(ZYME) | 22,970,388 | 22,970,388 | 0 | $392.33M | $604.81M | 27.61% | +$212.48M |
| Anaptysbio Inc | 7,880,094 | 7,880,094 | 0 | $241.29M | $382.03M | 17.44% | +$140.74M |
| Jazz Pharmaceuticals plcSHS USD(JAZZ) | 1,706,469 | 1,706,469 | 0 | $224.91M | $290.10M | 13.24% | +$65.19M |
| Crinetics Pharmaceuticals In | 4,288,120 | 4,288,120 | 0 | $178.60M | $199.61M | 9.11% | +$21.01M |
| Centessa Pharmaceuticals PlcADS | 550,000 | 3,115,000 | +2,565,000 | $13.34M | $77.91M | 3.56% | +$64.57M |
| CRISPR Therapeutics AGNAMEN AKT(CRSP) | 1,389,276 | 1,389,276 | 0 | $90.04M | $72.85M | 3.33% | -$17.19M |
| MBX Biosciences, Inc.(MBX) | 2,123,604 | 2,123,604 | 0 | $37.16M | $66.98M | 3.06% | +$29.82M |
| Immunome, Inc.(IMNM) | 4,079,415 | 2,855,590 | -1,223,825 | $47.77M | $61.34M | 2.80% | +$13.57M |
| ORIC Pharmaceuticals, Inc.(ORIC) | 6,728,116 | 6,728,116 | 0 | $80.74M | $55.04M | 2.51% | -$25.70M |
| Lakefront Biotherapeutics NVADR(LKFT) | 1,667,119 | 1,667,119 | 0 | $57.75M | $54.51M | 2.49% | -$3.23M |
| Xencor, Inc.(XNCR) | 6,144,767 | 3,251,112 | -2,893,655 | $72.08M | $49.77M | 2.27% | -$22.30M |
| BridgeBio Oncology Therapeutics, Inc.(BBOT) | 2,823,126 | 2,823,126 | 0 | $32.69M | $35.35M | 1.61% | +$2.65M |
| Eton Pharmaceuticals, Inc.(ETON) | 2,030,544 | 2,030,544 | 0 | $44.12M | $34.34M | 1.57% | -$9.79M |
| CG Oncology, Inc.(CGON) | 0 | 772,000 | +772,000 | $0 | $32.05M | 1.46% | +$32.05M |
| Zenas BioPharma, Inc.(ZBIO) | 0 | 789,500 | +789,500 | $0 | $28.67M | 1.31% | +$28.67M |
| Neurogene Inc.(NGNE) | 1,271,342 | 1,271,342 | 0 | $22.03M | $26.19M | 1.20% | +$4.16M |
| Structure Therapeutics IncADS | 0 | 334,380 | +334,380 | $0 | $23.26M | 1.06% | +$23.26M |
| Vaxcyte, Inc.(PCVX) | 0 | 450,000 | +450,000 | $0 | $20.76M | 0.95% | +$20.76M |
| Aquestive Therapeutics Inc | 2,625,000 | 2,625,000 | 0 | $14.67M | $16.96M | 0.77% | +$2.28M |
| Voyager Therapeutics, Inc.(VYGR) | 670,303 | 4,002,847 | +3,332,544 | $3.13M | $15.73M | 0.72% | +$12.60M |
| Atara Biotherapeutics Inc | 573,183 | 573,183 | 0 | $8.21M | $10.37M | 0.47% | +$2.16M |
| MannKind Corporation(MNKD) | 0 | 1,660,000 | +1,660,000 | $0 | $9.41M | 0.43% | +$9.41M |
| Nuvation Bio Inc.W EXP 02 10 202(NUVB) | 963,333 | 963,333 | 0 | $3.56M | $8.63M | 0.39% | +$5.07M |
| Evolus, Inc.(EOLS) | 0 | 675,000 | +675,000 | $0 | $4.49M | 0.20% | +$4.49M |
| iBio, Inc.(IBIO) | 0 | 2,228,000 | +2,228,000 | $0 | $4.30M | 0.20% | +$4.30M |
| Mereo BioPharma Group plcADS(MREO) | 0 | 7,856,466 | +7,856,466 | $0 | $3.27M | 0.15% | +$3.27M |
| CAMP4 THERAPEUTICS CORPORATION(CAMP) | 0 | 325,000 | +325,000 | $0 | $1.99M | 0.09% | +$1.99M |
| Surrozen, Inc.W EXP 08 01 203(SRZN) | 66,665 | 4,444 | -62,221 | $859.3K | $100.4K | 0.00% | -$758.9K |
| Alkermes plcSHS(ALKS) | 500,000 | 0 | -500,000 | $15.00M | $0 | — | -$15.00M |
| Apellis Pharmaceuticals Inc COM | 3,447,156 | 0 | -3,447,156 | $78.01M | $0 | — | -$78.01M |
| Avidity Biosciences Inc | 765,000 | 0 | -765,000 | $33.33M | $0 | — | -$33.33M |
| COMPASS Pathways plcADS(CMPS) | 265,137 | 0 | -265,137 | $1.52M | $0 | — | -$1.52M |
| Kura Oncology, Inc.(KURA) | 872,500 | 0 | -872,500 | $7.72M | $0 | — | -$7.72M |
| Madrigal Pharmaceuticals, Inc.(MDGL) | 75,000 | 0 | -75,000 | $34.40M | $0 | — | -$34.40M |
| Metsera Inc | 271,529 | 0 | -271,529 | $14.21M | $0 | — | -$14.21M |
| PepGen Inc.(PEPG) | 800,000 | 0 | -800,000 | $3.70M | $0 | — | -$3.70M |
| Prime Medicine, Inc.(PRME) | 1,543,326 | 0 | -1,543,326 | $8.55M | $0 | — | -$8.55M |
| Tango Therapeutics, Inc.(TNGX) | 10,630,736 | 0 | -10,630,736 | $89.30M | $0 | — | -$89.30M |
| uniQure N.V.SHS(QURE) | 3,988,971 | 0 | -3,988,971 | $232.84M | $0 | — | -$232.84M |