Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q4 2023 ▲▼ | Q1 2024 ▲▼ | Change ▲▼ | Q4 2023 ▲▼ | Q1 2024 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| ELI LILLY & CO(LLY) | 69,500 | 103,250 | +33,750 | 40,513 | 80,324 | 2.04% | +39,811 |
| MADRIGAL PHARMACEUTICALS INC(MDGL) | 198,169 | 285,931 | +87,762 | 45,852 | 76,355 | 1.94% | +30,503 |
| SURGERY PARTNERS INC(SGRY) | 0 | 985,000 | +985,000 | 0 | 29,383 | 0.75% | +29,383 |
| MERUS N V | 872,069 | 1,146,560 | +274,491 | 23,982 | 51,630 | 1.31% | +27,648 |
| OSCAR HEALTH INC(OSCR) | 735,000 | 2,110,000 | +1,375,000 | 6,725 | 31,376 | 0.80% | +24,650 |
| KYMERA THERAPEUTICS INC(KYMR) | 1,522,238 | 1,522,238 | 0 | 38,756 | 61,194 | 1.56% | +22,438 |
| VIKING THERAPEUTICS INC(VKTX) | 0 | 261,000 | +261,000 | 0 | 21,402 | 0.54% | +21,402 |
| SHOCKWAVE MED INC | 120,000 | 135,000 | +15,000 | 22,867 | 43,960 | 1.12% | +21,093 |
| FRESHPET INC(FRPT) | 662,500 | 662,500 | 0 | 57,479 | 76,757 | 1.95% | +19,279 |
| CELLDEX THERAPEUTICS INC NEW(CLDX) | 969,646 | 1,372,185 | +402,539 | 38,456 | 57,591 | 1.46% | +19,134 |
| NOVO-NORDISK A S(NVO) | 0 | 147,500 | +147,500 | 0 | 18,939 | 0.48% | +18,939 |
| INTUITIVE SURGICAL INC | 298,500 | 298,500 | 0 | 100,702 | 119,128 | 3.03% | +18,426 |
| PHARVARIS N V COM | 0 | 752,924 | +752,924 | 0 | 17,400 | 0.44% | +17,400 |
| VERA THERAPEUTICS INC(VERA) | 0 | 341,168 | +341,168 | 0 | 14,711 | 0.37% | +14,711 |
| CRINETICS PHARMACEUTICALS IN(CRNX) | 0 | 289,400 | +289,400 | 0 | 13,547 | 0.34% | +13,547 |
| BOSTON SCIENTIFIC CORP(BSX) | 1,232,500 | 1,232,500 | 0 | 71,251 | 84,414 | 2.15% | +13,163 |
| CHARLES RIV LABS INTL INC(CRL) | 0 | 48,500 | +48,500 | 0 | 13,141 | 0.33% | +13,141 |
| DYNE THERAPEUTICS INC(DYN) | 0 | 451,824 | +451,824 | 0 | 12,827 | 0.33% | +12,827 |
| INOZYME PHARMA INC | 3,681,174 | 3,681,174 | 0 | 15,682 | 28,198 | 0.72% | +12,516 |
| EDWARDS LIFESCIENCES CORP | 647,300 | 647,300 | 0 | 49,357 | 61,856 | 1.57% | +12,499 |
| JASPER THERAPEUTICS INC(JSPR) | 0 | 404,335 | +404,335 | 0 | 11,871 | 0.30% | +11,871 |
| ALIGN TECHNOLOGY INC | 220,000 | 220,000 | 0 | 60,280 | 72,142 | 1.83% | +11,862 |
| SAREPTA THERAPEUTICS INC(SRPT) | 327,600 | 327,600 | 0 | 31,590 | 42,411 | 1.08% | +10,821 |
| ACADIA HEALTHCARE COMPANY IN(ACHC) | 1,073,500 | 1,177,500 | +104,000 | 83,475 | 93,282 | 2.37% | +9,806 |
| NUVALENT INC | 0 | 125,302 | +125,302 | 0 | 9,409 | 0.24% | +9,409 |
| REVOLUTION MEDICINES INC(RVMD) | 725,152 | 923,681 | +198,529 | 20,797 | 29,770 | 0.76% | +8,973 |
| NEUMORA THERAPEUTICS INC.(NMRA) | 0 | 646,118 | +646,118 | 0 | 8,884 | 0.23% | +8,884 |
| AZENTA INC(AZTA) | 507,500 | 694,750 | +187,250 | 33,059 | 41,880 | 1.06% | +8,821 |
| DEXCOM INC(DXCM) | 596,000 | 596,750 | +750 | 73,958 | 82,769 | 2.10% | +8,812 |
| MEREO BIOPHARMA GROUP PLC(MREO) | 7,983,851 | 8,142,109 | +158,258 | 18,443 | 26,869 | 0.68% | +8,426 |
| IRHYTHM TECHNOLOGIES INC(IRTC) | 350,750 | 392,250 | +41,500 | 37,544 | 45,501 | 1.16% | +7,957 |
| INSPIRE MED SYS INC(INSP) | 99,000 | 130,500 | +31,500 | 20,140 | 28,030 | 0.71% | +7,891 |
| MACROGENICS INC(MGNX) | 1,178,796 | 1,305,250 | +126,454 | 11,340 | 19,213 | 0.49% | +7,873 |
| AKERO THERAPEUTICS INC | 1,081,064 | 1,299,888 | +218,824 | 25,243 | 32,835 | 0.83% | +7,592 |
| ENLIVEN THERAPEUTICS INC | 0 | 428,571 | +428,571 | 0 | 7,539 | 0.19% | +7,539 |
| CG ONCOLOGY INC(CGON) | 0 | 170,859 | +170,859 | 0 | 7,501 | 0.19% | +7,501 |
| ASCENDIS PHARMA A/S(ASND) | 290,000 | 290,000 | 0 | 36,526 | 43,839 | 1.11% | +7,314 |
| APPLIED THERAPEUTICS INC | 895,195 | 1,497,918 | +602,723 | 2,999 | 10,186 | 0.26% | +7,187 |
| BIOHAVEN LTD(BHVN) | 0 | 126,984 | +126,984 | 0 | 6,945 | 0.18% | +6,945 |
| AUTOLUS THERAPEUTICS PLC(AUTL) | 0 | 1,032,988 | +1,032,988 | 0 | 6,590 | 0.17% | +6,590 |
| MERSANA THERAPEUTICS INC | 3,046,782 | 3,046,782 | 0 | 7,069 | 13,650 | 0.35% | +6,581 |
| STRUCTURE THERAPEUTICS INC | 286,676 | 412,649 | +125,973 | 11,685 | 17,686 | 0.45% | +6,001 |
| WEST PHARMACEUTICAL SVSC INC(WST) | 137,250 | 137,250 | 0 | 48,328 | 54,311 | 1.38% | +5,983 |
| KRYSTAL BIOTECH INC(KRYS) | 103,969 | 103,969 | 0 | 12,898 | 18,499 | 0.47% | +5,601 |
| PHREESIA INC(PHR) | 2,206,700 | 2,365,000 | +158,300 | 51,085 | 56,594 | 1.44% | +5,509 |
| COLLEGIUM PHARMACEUTICAL INC(COLL) | 562,000 | 562,000 | 0 | 17,298 | 21,817 | 0.55% | +4,518 |
| KYVERNA THERAPEUTICS INC(KYTX) | 0 | 178,963 | +178,963 | 0 | 4,445 | 0.11% | +4,445 |
| AGIOS PHARMACEUTICALS INC(AGIO) | 2,152,173 | 1,764,505 | -387,668 | 47,929 | 51,594 | 1.31% | +3,665 |
| EDAP TMS S A(FOCL) | 1,386,425 | 1,475,000 | +88,575 | 7,320 | 10,841 | 0.28% | +3,521 |
| VINCERX PHARMA INC | 891,719 | 891,719 | 0 | 1,052 | 4,512 | 0.11% | +3,460 |
| ARGENX SE(ARGX) | 229,250 | 229,250 | 0 | 87,214 | 90,260 | 2.29% | +3,047 |
| COMPASS THERAPEUTICS INC(CMPX) | 5,513,788 | 5,513,788 | 0 | 8,602 | 10,917 | 0.28% | +2,316 |
| AURINIA PHARMACEUTICALS INC(AUPH) | 412,570 | 1,150,347 | +737,777 | 3,709 | 5,763 | 0.15% | +2,054 |
| FULCRUM THERAPEUTICS INC(FULC) | 727,673 | 727,673 | 0 | 4,912 | 6,869 | 0.17% | +1,957 |
| ADAPTIMMUNE THERAPEUTICS PLC(ADAPY) | 2,425,468 | 2,425,468 | 0 | 1,923 | 3,832 | 0.10% | +1,909 |
| BEAM THERAPEUTICS INC(BEAM) | 111,430 | 147,510 | +36,080 | 3,033 | 4,874 | 0.12% | +1,841 |
| DISC MEDICINE INC(IRON) | 363,468 | 363,468 | 0 | 20,994 | 22,630 | 0.58% | +1,636 |
| TRAVERE THERAPEUTICS INC(TVTX) | 2,771,446 | 3,424,818 | +653,372 | 24,915 | 26,405 | 0.67% | +1,490 |
| ESSA PHARMA INC | 677,005 | 677,005 | 0 | 4,468 | 5,748 | 0.15% | +1,280 |
| GOSSAMER BIO INC(GOSS) | 3,266,960 | 3,266,960 | 0 | 2,981 | 3,855 | 0.10% | +874 |
| COMPUGEN LTD(CGEN) | 1,289,990 | 1,289,990 | 0 | 2,554 | 3,328 | 0.08% | +774 |
| XILIO THERAPEUTICS INC(XLO) | 1,440,759 | 1,440,759 | 0 | 792 | 1,556 | 0.04% | +764 |
| ACUMEN PHARMACEUTICALS INC(ABOS) | 2,300,059 | 2,300,059 | 0 | 8,832 | 9,315 | 0.24% | +483 |
| GOSSAMER BIO INC(GOSS) | 0 | 0 | 0 | 3,488 | 3,845 | 0.10% | +356 |
| ACLARIS THERAPEUTICS INC(ACRS) | 2,998,495 | 2,753,495 | -245,000 | 3,148 | 3,414 | 0.09% | +266 |
| MINERALYS THERAPEUTICS INC(MLYS) | 1,167,492 | 792,615 | -374,877 | 10,040 | 10,233 | 0.26% | +192 |
| SAGIMET BIOSCIENCES INC(SGMT) | 738,355 | 770,671 | +32,316 | 4,002 | 4,177 | 0.11% | +175 |
| TALPHERA INC(TLPH) | 316,460 | 316,460 | 0 | 233 | 326 | 0.01% | +93 |
| BIOMEA FUSION INC(BMEA) | 181,147 | 181,147 | 0 | 2,630 | 2,708 | 0.07% | +78 |
| TRAVERE THERAPEUTICS INC | 0 | 0 | 0 | 2,768 | 2,842 | 0.07% | +74 |
| NEUROCRINE BIOSCIENCES INC(NBIX) | 0 | 0 | 0 | 1,753 | 1,807 | 0.05% | +54 |
| RENEO PHARMACEUTICALS INC | 751,730 | 751,730 | 0 | 1,203 | 1,248 | 0.03% | +45 |
| NUVATION BIO INC(NUVB) | 134,028 | 134,028 | 0 | 8 | 41 | 0.00% | +33 |
| VIGIL NEUROSCIENCE INC | 471,958 | 471,958 | 0 | 1,595 | 1,609 | 0.04% | +14 |
| NEVRO CORP | 0 | 0 | 0 | 482 | 474 | 0.01% | -8 |
| NOVAVAX INC(NVAX) | 537,625 | 537,625 | 0 | 2,581 | 2,570 | 0.07% | -11 |
| EVOLENT HEALTH INC(EVH) | 3,960,000 | 3,987,500 | +27,500 | 130,799 | 130,750 | 3.32% | -49 |
| WARBY PARKER INC(WRBY) | 2,028,300 | 2,080,000 | +51,700 | 28,599 | 28,309 | 0.72% | -290 |
| ULTRAGENYX PHARMACEUTICAL IN(RARE) | 1,754,038 | 1,774,938 | +20,900 | 83,878 | 82,872 | 2.11% | -1,006 |
| LEAP THERAPEUTICS INC(CYPH) | 832,937 | 911,937 | +79,000 | 3,453 | 2,426 | 0.06% | -1,027 |
| PLIANT THERAPEUTICS INC(PLRX) | 384,996 | 384,996 | 0 | 6,972 | 5,736 | 0.15% | -1,236 |
| BIOMARIN PHARMACEUTICAL INC(BMRN) | 148,832 | 148,832 | 0 | 14,350 | 12,999 | 0.33% | -1,351 |
| AMICUS THERAPEUTICS INC COM | 1,063,806 | 1,152,656 | +88,850 | 15,095 | 13,578 | 0.35% | -1,517 |
| LEGEND BIOTECH CORP(LEGN) | 492,444 | 499,486 | +7,042 | 29,630 | 28,016 | 0.71% | -1,614 |
| BIOCRYST PHARMACEUTICALS INC(BCRX) | 3,270,381 | 3,496,256 | +225,875 | 19,590 | 17,761 | 0.45% | -1,829 |
| EXACT SCIENCES CORP(EXK) | 1,019,500 | 1,059,750 | +40,250 | 75,423 | 73,186 | 1.86% | -2,236 |
| PULMONX CORP(LUNG) | 652,400 | 652,400 | 0 | 8,318 | 6,048 | 0.15% | -2,270 |
| DYNAVAX TECHNOLOGIES CORP | 1,675,474 | 1,675,474 | 0 | 23,423 | 20,793 | 0.53% | -2,630 |
| IDEXX LABS INC(IDXX) | 179,250 | 179,250 | 0 | 99,493 | 96,782 | 2.46% | -2,710 |
| OLINK HLDG AB | 1,676,500 | 1,676,500 | 0 | 42,164 | 39,415 | 1.00% | -2,749 |
| XENON PHARMACEUTICALS INC(XENE) | 1,255,577 | 1,255,577 | 0 | 57,832 | 54,053 | 1.37% | -3,779 |
| RHYTHM PHARMACEUTICALS INC(RYTM) | 1,522,893 | 1,522,893 | 0 | 70,007 | 65,987 | 1.68% | -4,020 |
| IMMUNOVANT INC(IMVT) | 983,301 | 1,150,123 | +166,822 | 41,426 | 37,160 | 0.94% | -4,266 |
| ACCOLADE INC | 3,485,000 | 3,540,000 | +55,000 | 41,855 | 37,099 | 0.94% | -4,756 |
| PACIRA BIOSCIENCES INC(PCRX) | 1,055,500 | 1,055,500 | 0 | 35,613 | 30,842 | 0.78% | -4,771 |
| AMYLYX PHARMACEUTICALS INC(AMLX) | 535,012 | 1,011,412 | +476,400 | 7,875 | 2,872 | 0.07% | -5,003 |
| SPRUCE BIOSCIENCES INC | 2,609,125 | 2,609,125 | 0 | 7,645 | 2,051 | 0.05% | -5,594 |
| LIFESTANCE HEALTH GROUP INC(LFST) | 4,535,000 | 4,780,000 | +245,000 | 35,509 | 29,493 | 0.75% | -6,016 |
| NEVRO CORP | 1,025,000 | 1,065,000 | +40,000 | 22,058 | 15,379 | 0.39% | -6,679 |
| PROTHENA CORP PLC SHS | 625,048 | 625,048 | 0 | 22,714 | 15,482 | 0.39% | -7,232 |