Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q1 2024 ▲▼ | Q2 2024 ▲▼ | Change ▲▼ | Q1 2024 ▲▼ | Q2 2024 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| INSMED INC(INSM) | 0 | 808,356 | +808,356 | 0 | 54,160 | 1.63% | +54,160 |
| ELI LILLY & CO(LLY) | 103,250 | 121,500 | +18,250 | 80,324 | 110,004 | 3.32% | +29,679 |
| BLUEPRINT MEDICINES CORP | 2,498,448 | 2,460,417 | -38,031 | 237,003 | 265,184 | 8.00% | +28,181 |
| UNITEDHEALTH GROUP INC(UNH) | 230,000 | 275,000 | +45,000 | 113,781 | 140,047 | 4.23% | +26,266 |
| JOHNSON & JOHNSON(JNJ) | 0 | 170,000 | +170,000 | 0 | 24,847 | 0.75% | +24,847 |
| ALNYLAM PHARMACEUTICALS INC(ALNY) | 244,000 | 250,000 | +6,000 | 36,466 | 60,750 | 1.83% | +24,284 |
| STRUCTURE THERAPEUTICS INC | 412,649 | 999,862 | +587,213 | 17,686 | 39,265 | 1.18% | +21,578 |
| MIRUM PHARMACEUTICALS INC(MIRM) | 1,856,564 | 1,772,038 | -84,526 | 46,637 | 60,586 | 1.83% | +13,949 |
| INTUITIVE SURGICAL INC | 298,500 | 298,500 | 0 | 119,128 | 132,788 | 4.01% | +13,659 |
| CULLINAN THERAPEUTICS INC(CGEM) | 0 | 658,338 | +658,338 | 0 | 11,481 | 0.35% | +11,481 |
| TRAVERE THERAPEUTICS INC(TVTX) | 3,424,818 | 4,482,265 | +1,057,447 | 26,405 | 36,844 | 1.11% | +10,439 |
| NUVALENT INC | 125,302 | 255,989 | +130,687 | 9,409 | 19,419 | 0.59% | +10,010 |
| ARGENX SE(ARGX) | 229,250 | 229,250 | 0 | 90,260 | 98,587 | 2.98% | +8,326 |
| MERUS N V | 1,146,560 | 1,001,073 | -145,487 | 51,630 | 59,233 | 1.79% | +7,604 |
| SPRINGWORKS THERAPEUTICS INC | 0 | 199,855 | +199,855 | 0 | 7,529 | 0.23% | +7,529 |
| REVOLUTION MEDICINES INC(RVMD) | 923,681 | 943,195 | +19,514 | 29,770 | 36,605 | 1.10% | +6,835 |
| MEREO BIOPHARMA GROUP PLC(MREO) | 8,142,109 | 9,283,492 | +1,141,383 | 26,869 | 33,421 | 1.01% | +6,552 |
| NOVAVAX INC(NVAX) | 537,625 | 675,000 | +137,375 | 2,570 | 8,546 | 0.26% | +5,976 |
| APELLIS PHARMACEUTICALS INC COM | 0 | 140,700 | +140,700 | 0 | 5,397 | 0.16% | +5,397 |
| WARBY PARKER INC(WRBY) | 2,080,000 | 2,080,000 | 0 | 28,309 | 33,405 | 1.01% | +5,096 |
| BIOCRYST PHARMACEUTICALS INC(BCRX) | 3,496,256 | 3,619,258 | +123,002 | 17,761 | 22,367 | 0.67% | +4,606 |
| AGILON HEALTH INC(AGL) | 8,835,000 | 8,900,000 | +65,000 | 53,894 | 58,206 | 1.76% | +4,313 |
| PERSPECTIVE THERAPEUTICS INC(CATX) | 0 | 401,196 | +401,196 | 0 | 4,000 | 0.12% | +4,000 |
| HUMANA INC(HUM) | 147,408 | 147,408 | 0 | 51,109 | 55,079 | 1.66% | +3,970 |
| DYNE THERAPEUTICS INC(DYN) | 451,824 | 461,028 | +9,204 | 12,827 | 16,270 | 0.49% | +3,442 |
| ENLIVEN THERAPEUTICS INC | 428,571 | 428,571 | 0 | 7,539 | 10,016 | 0.30% | +2,477 |
| SAREPTA THERAPEUTICS INC(SRPT) | 327,600 | 284,000 | -43,600 | 42,411 | 44,872 | 1.35% | +2,461 |
| NOVO-NORDISK A S(NVO) | 147,500 | 147,500 | 0 | 18,939 | 21,054 | 0.64% | +2,115 |
| ZAI LAB LTD(ZLAB) | 1,297,123 | 1,297,873 | +750 | 20,780 | 22,492 | 0.68% | +1,712 |
| XILIO THERAPEUTICS INC(XLO) | 1,440,759 | 3,003,259 | +1,562,500 | 1,556 | 2,846 | 0.09% | +1,290 |
| KORRO BIO INC(KRRO) | 0 | 35,719 | +35,719 | 0 | 1,210 | 0.04% | +1,210 |
| ALLAKOS INC | 0 | 1,200,409 | +1,200,409 | 0 | 1,200 | 0.04% | +1,200 |
| BEAM THERAPEUTICS INC(BEAM) | 147,510 | 249,923 | +102,413 | 4,874 | 5,856 | 0.18% | +982 |
| AURINIA PHARMACEUTICALS INC(AUPH) | 1,150,347 | 1,179,740 | +29,393 | 5,763 | 6,736 | 0.20% | +973 |
| GOSSAMER BIO INC(GOSS) | 0 | 0 | 0 | 3,845 | 4,736 | 0.14% | +891 |
| KRYSTAL BIOTECH INC(KRYS) | 103,969 | 105,569 | +1,600 | 18,499 | 19,387 | 0.59% | +887 |
| VIGIL NEUROSCIENCE INC | 471,958 | 471,958 | 0 | 1,609 | 1,888 | 0.06% | +278 |
| LEAP THERAPEUTICS INC(CYPH) | 911,937 | 1,266,546 | +354,609 | 2,426 | 2,482 | 0.07% | +57 |
| TRAVERE THERAPEUTICS INC | 0 | 0 | 0 | 2,842 | 2,888 | 0.09% | +46 |
| NEVRO CORP | 0 | 0 | 0 | 474 | 483 | 0.01% | +9 |
| NUVATION BIO INC(NUVB) | 134,028 | 134,028 | 0 | 41 | 21 | 0.00% | -19 |
| TALPHERA INC(TLPH) | 316,460 | 316,460 | 0 | 326 | 282 | 0.01% | -44 |
| ACLARIS THERAPEUTICS INC(ACRS) | 2,753,495 | 2,753,495 | 0 | 3,414 | 3,029 | 0.09% | -385 |
| BIOMARIN PHARMACEUTICAL INC(BMRN) | 148,832 | 151,000 | +2,168 | 12,999 | 12,432 | 0.38% | -567 |
| CRINETICS PHARMACEUTICALS IN(CRNX) | 289,400 | 289,400 | 0 | 13,547 | 12,962 | 0.39% | -585 |
| CHARLES RIV LABS INTL INC(CRL) | 48,500 | 60,250 | +11,750 | 13,141 | 12,446 | 0.38% | -695 |
| SPRUCE BIOSCIENCES INC | 2,609,125 | 2,609,125 | 0 | 2,051 | 1,351 | 0.04% | -700 |
| GOSSAMER BIO INC(GOSS) | 3,266,960 | 3,266,960 | 0 | 3,855 | 2,943 | 0.09% | -912 |
| VERA THERAPEUTICS INC(VERA) | 341,168 | 381,192 | +40,024 | 14,711 | 13,792 | 0.42% | -920 |
| RENEO PHARMACEUTICALS INC | 751,730 | 0 | -751,730 | 1,248 | 0 | — | -1,248 |
| NEUMORA THERAPEUTICS INC.(NMRA) | 646,118 | 760,007 | +113,889 | 8,884 | 7,471 | 0.23% | -1,413 |
| ADAPTIMMUNE THERAPEUTICS PLC(ADAPY) | 2,425,468 | 2,425,468 | 0 | 3,832 | 2,365 | 0.07% | -1,468 |
| SAGIMET BIOSCIENCES INC(SGMT) | 770,671 | 787,808 | +17,137 | 4,177 | 2,694 | 0.08% | -1,483 |
| AMICUS THERAPEUTICS INC COM | 1,152,656 | 1,218,580 | +65,924 | 13,578 | 12,088 | 0.36% | -1,490 |
| PLIANT THERAPEUTICS INC(PLRX) | 384,996 | 384,996 | 0 | 5,736 | 4,139 | 0.12% | -1,598 |
| COMPUGEN LTD(CGEN) | 1,289,990 | 989,990 | -300,000 | 3,328 | 1,663 | 0.05% | -1,665 |
| NEUROCRINE BIOSCIENCES INC(NBIX) | 0 | 0 | 0 | 1,807 | 0 | — | -1,807 |
| BIOMEA FUSION INC(BMEA) | 181,147 | 181,147 | 0 | 2,708 | 815 | 0.02% | -1,893 |
| PULMONX CORP(LUNG) | 652,400 | 652,400 | 0 | 6,048 | 4,136 | 0.12% | -1,912 |
| ESSA PHARMA INC | 677,005 | 677,005 | 0 | 5,748 | 3,561 | 0.11% | -2,187 |
| FULCRUM THERAPEUTICS INC(FULC) | 727,673 | 727,673 | 0 | 6,869 | 4,512 | 0.14% | -2,358 |
| BIOHAVEN LTD(BHVN) | 126,984 | 127,558 | +574 | 6,945 | 4,428 | 0.13% | -2,517 |
| PROTHENA CORP PLC SHS | 625,048 | 625,048 | 0 | 15,482 | 12,901 | 0.39% | -2,581 |
| JASPER THERAPEUTICS INC(JSPR) | 404,335 | 404,335 | 0 | 11,871 | 9,178 | 0.28% | -2,693 |
| IRHYTHM TECHNOLOGIES INC(IRTC) | 392,250 | 397,500 | +5,250 | 45,501 | 42,787 | 1.29% | -2,714 |
| EDAP TMS S A(FOCL) | 1,475,000 | 1,475,000 | 0 | 10,841 | 8,024 | 0.24% | -2,817 |
| AMYLYX PHARMACEUTICALS INC(AMLX) | 1,011,412 | 0 | -1,011,412 | 2,872 | 0 | — | -2,872 |
| APPLIED THERAPEUTICS INC | 1,497,918 | 1,555,004 | +57,086 | 10,186 | 7,262 | 0.22% | -2,924 |
| AUTOLUS THERAPEUTICS PLC(AUTL) | 1,032,988 | 1,032,988 | 0 | 6,590 | 3,595 | 0.11% | -2,996 |
| KYVERNA THERAPEUTICS INC(KYTX) | 178,963 | 178,963 | 0 | 4,445 | 1,342 | 0.04% | -3,103 |
| PHARVARIS N V COM | 752,924 | 756,931 | +4,007 | 17,400 | 14,230 | 0.43% | -3,170 |
| NEVRO CORP | 1,065,000 | 1,381,500 | +316,500 | 15,379 | 11,632 | 0.35% | -3,746 |
| ACUMEN PHARMACEUTICALS INC(ABOS) | 2,300,059 | 2,300,059 | 0 | 9,315 | 5,566 | 0.17% | -3,749 |
| VINCERX PHARMA INC | 891,719 | 891,719 | 0 | 4,512 | 722 | 0.02% | -3,790 |
| ULTRAGENYX PHARMACEUTICAL IN(RARE) | 1,774,938 | 1,924,072 | +149,134 | 82,872 | 79,079 | 2.39% | -3,792 |
| ASCENDIS PHARMA A/S(ASND) | 290,000 | 290,000 | 0 | 43,839 | 39,550 | 1.19% | -4,289 |
| XENON PHARMACEUTICALS INC(XENE) | 1,255,577 | 1,272,877 | +17,300 | 54,053 | 49,629 | 1.50% | -4,423 |
| AZENTA INC(AZTA) | 694,750 | 696,000 | +1,250 | 41,880 | 36,624 | 1.11% | -5,256 |
| PHREESIA INC(PHR) | 2,365,000 | 2,417,500 | +52,500 | 56,594 | 51,251 | 1.55% | -5,343 |
| COMPASS THERAPEUTICS INC(CMPX) | 5,513,788 | 5,513,788 | 0 | 10,917 | 5,514 | 0.17% | -5,404 |
| LEGEND BIOTECH CORP(LEGN) | 499,486 | 505,786 | +6,300 | 28,016 | 22,401 | 0.68% | -5,615 |
| LIFESTANCE HEALTH GROUP INC(LFST) | 4,780,000 | 4,827,700 | +47,700 | 29,493 | 23,704 | 0.72% | -5,789 |
| MINERALYS THERAPEUTICS INC(MLYS) | 792,615 | 378,932 | -413,683 | 10,233 | 4,434 | 0.13% | -5,799 |
| CELLDEX THERAPEUTICS INC NEW(CLDX) | 1,372,185 | 1,398,994 | +26,809 | 57,591 | 51,777 | 1.56% | -5,814 |
| IMMUNOVANT INC(IMVT) | 1,150,123 | 1,185,654 | +35,531 | 37,160 | 31,301 | 0.94% | -5,859 |
| DYNAVAX TECHNOLOGIES CORP | 1,675,474 | 1,292,637 | -382,837 | 20,793 | 14,516 | 0.44% | -6,276 |
| WEST PHARMACEUTICAL SVSC INC(WST) | 137,250 | 145,500 | +8,250 | 54,311 | 47,926 | 1.45% | -6,385 |
| AGIOS PHARMACEUTICALS INC(AGIO) | 1,764,505 | 1,044,261 | -720,244 | 51,594 | 45,029 | 1.36% | -6,566 |
| CG ONCOLOGY INC(CGON) | 170,859 | 0 | -170,859 | 7,501 | 0 | — | -7,501 |
| MERSANA THERAPEUTICS INC | 3,046,782 | 3,046,782 | 0 | 13,650 | 6,124 | 0.18% | -7,526 |
| MADRIGAL PHARMACEUTICALS INC(MDGL) | 285,931 | 245,499 | -40,432 | 76,355 | 68,779 | 2.08% | -7,576 |
| AKERO THERAPEUTICS INC | 1,299,888 | 1,074,261 | -225,627 | 32,835 | 25,202 | 0.76% | -7,633 |
| PACIRA BIOSCIENCES INC(PCRX) | 1,055,500 | 785,000 | -270,500 | 30,842 | 22,459 | 0.68% | -8,383 |
| IMMATICS N.V(IMTX) | 848,751 | 0 | -848,751 | 8,920 | 0 | — | -8,920 |
| INSPIRE MED SYS INC(INSP) | 130,500 | 130,000 | -500 | 28,030 | 17,398 | 0.53% | -10,632 |
| EDWARDS LIFESCIENCES CORP | 647,300 | 550,000 | -97,300 | 61,856 | 50,804 | 1.53% | -11,052 |
| OSCAR HEALTH INC(OSCR) | 2,110,000 | 1,251,500 | -858,500 | 31,376 | 19,799 | 0.60% | -11,577 |
| INOZYME PHARMA INC | 3,681,174 | 3,698,374 | +17,200 | 28,198 | 16,495 | 0.50% | -11,703 |
| RHYTHM PHARMACEUTICALS INC(RYTM) | 1,522,893 | 1,280,493 | -242,400 | 65,987 | 52,577 | 1.59% | -13,410 |
| ACADIA HEALTHCARE COMPANY IN(ACHC) | 1,177,500 | 1,177,500 | 0 | 93,282 | 79,528 | 2.40% | -13,753 |