Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q1 2025 ▲▼ | Q2 2025 ▲▼ | Change ▲▼ | Q1 2025 ▲▼ | Q2 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| argenx SEADR(ARGX) | 175,750 | 175,750 | 0 | $104.02M | $96.88M | 6.04% | -$7.14M |
| Eli Lilly and Company(LLY) | 113,500 | 116,500 | +3,000 | $93.74M | $90.82M | 5.66% | -$2.93M |
| Merus N V | 980,751 | 1,063,608 | +82,857 | $41.28M | $55.95M | 3.49% | +$14.67M |
| Rhythm Pharmaceuticals, Inc.(RYTM) | 834,188 | 861,153 | +26,965 | $44.19M | $54.42M | 3.39% | +$10.23M |
| Insmed Incorporated(INSM) | 515,900 | 525,000 | +9,100 | $39.36M | $52.84M | 3.29% | +$13.48M |
| Ultragenyx Pharmaceutical Inc.(RARE) | 1,394,434 | 1,391,072 | -3,362 | $50.49M | $50.58M | 3.15% | +$86.9K |
| Revolution Medicines, Inc.(RVMD) | 1,281,640 | 1,330,960 | +49,320 | $45.32M | $48.97M | 3.05% | +$3.65M |
| Intuitive Surgical, Inc.(ISRG) | 102,000 | 82,000 | -20,000 | $50.52M | $44.56M | 2.78% | -$5.96M |
| Madrigal Pharmaceuticals, Inc.(MDGL) | 166,698 | 140,296 | -26,402 | $55.22M | $42.46M | 2.65% | -$12.76M |
| Mirum Pharmaceuticals, Inc.(MIRM) | 951,765 | 818,206 | -133,559 | $42.88M | $41.64M | 2.59% | -$1.24M |
| Boston Scientific Corporation(BSX) | 277,000 | 355,000 | +78,000 | $27.94M | $38.13M | 2.38% | +$10.19M |
| Ascendis Pharma A/SADR(ASND) | 216,000 | 217,000 | +1,000 | $33.67M | $37.45M | 2.33% | +$3.79M |
| iRhythm Holdings, Inc.(IRTC) | 254,300 | 242,500 | -11,800 | $26.62M | $37.34M | 2.33% | +$10.72M |
| Akero Therapeutics Inc | 672,759 | 640,526 | -32,233 | $27.23M | $34.18M | 2.13% | +$6.95M |
| Penumbra, Inc.(PEN) | 171,000 | 128,500 | -42,500 | $45.73M | $32.98M | 2.05% | -$12.75M |
| Agios Pharmaceuticals, Inc.(AGIO) | 342,180 | 989,745 | +647,565 | $10.03M | $32.92M | 2.05% | +$22.89M |
| Alnylam Pharmaceuticals, Inc.(ALNY) | 143,250 | 100,000 | -43,250 | $38.68M | $32.61M | 2.03% | -$6.07M |
| Evolent Health, Inc.CL A(EVH) | 2,695,700 | 2,820,700 | +125,000 | $25.53M | $31.76M | 1.98% | +$6.23M |
| Zai Lab LimitedADR(ZLAB) | 904,592 | 871,392 | -33,200 | $32.69M | $30.47M | 1.90% | -$2.22M |
| Endeavour Silver Corp.(EXK) | 480,000 | 572,000 | +92,000 | $20.78M | $30.40M | 1.89% | +$9.62M |
| Xenon Pharmaceuticals Inc.(XENE) | 931,681 | 931,681 | 0 | $31.26M | $29.16M | 1.82% | -$2.10M |
| Travere Therapeutics, Inc.(TVTX) | 2,921,196 | 1,908,208 | -1,012,988 | $52.35M | $28.24M | 1.76% | -$24.11M |
| Scholar Rock Holding Corporation(SRRK) | 761,541 | 794,133 | +32,592 | $24.48M | $28.13M | 1.75% | +$3.64M |
| DexCom, Inc.(DXCM) | 397,650 | 286,750 | -110,900 | $27.16M | $25.03M | 1.56% | -$2.13M |
| Phreesia, Inc.(PHR) | 1,148,336 | 837,300 | -311,036 | $29.35M | $23.83M | 1.48% | -$5.52M |
| Blueprint Medicines Corp | 1,007,569 | 185,500 | -822,069 | $89.18M | $23.78M | 1.48% | -$65.40M |
| Structure Therapeutics IncADS | 1,132,979 | 1,135,879 | +2,900 | $19.61M | $23.56M | 1.47% | +$3.95M |
| Tenet Healthcare Corporation(THC) | 130,000 | 130,000 | 0 | $17.48M | $22.88M | 1.43% | +$5.39M |
| Caris Life Sciences, Inc.(CAI) | 0 | 793,651 | +793,651 | $0 | $21.21M | 1.32% | +$21.21M |
| Kymera Therapeutics, Inc.(KYMR) | 794,437 | 450,374 | -344,063 | $21.74M | $19.65M | 1.22% | -$2.09M |
| Omada Health, Inc.(OMDA) | 0 | 919,951 | +919,951 | $0 | $16.84M | 1.05% | +$16.84M |
| Celldex Therapeutics, Inc.(CLDX) | 812,653 | 812,653 | 0 | $14.75M | $16.54M | 1.03% | +$1.79M |
| Azenta, Inc.(AZTA) | 475,000 | 530,400 | +55,400 | $16.45M | $16.33M | 1.02% | -$128.3K |
| Acadia Healthcare Company, Inc.(ACHC) | 681,100 | 696,000 | +14,900 | $20.65M | $15.79M | 0.98% | -$4.86M |
| UnitedHealth Group Incorporated(UNH) | 100,500 | 50,500 | -50,000 | $52.64M | $15.75M | 0.98% | -$36.88M |
| Tarsus Pharmaceuticals, Inc.(TARS) | 354,376 | 373,750 | +19,374 | $18.20M | $15.14M | 0.94% | -$3.06M |
| Summit Therapeutics Inc.(SMMT) | 995,000 | 710,000 | -285,000 | $19.19M | $15.11M | 0.94% | -$4.08M |
| agilon health, inc.(AGL) | 6,950,000 | 6,550,400 | -399,600 | $30.09M | $15.07M | 0.94% | -$15.03M |
| Oscar Health, Inc.CL A(OSCR) | 1,050,000 | 700,000 | -350,000 | $13.77M | $15.01M | 0.94% | +$1.24M |
| Vera Therapeutics, Inc.CL A(VERA) | 520,796 | 617,396 | +96,600 | $12.51M | $14.55M | 0.91% | +$2.04M |
| Enliven Therapeutics Inc | 465,871 | 701,408 | +235,537 | $9.17M | $14.07M | 0.88% | +$4.90M |
| Inspire Medical Systems, Inc.(INSP) | 99,250 | 107,500 | +8,250 | $15.81M | $13.95M | 0.87% | -$1.86M |
| Soleno Therapeutics Inc | 124,095 | 154,528 | +30,433 | $8.87M | $12.95M | 0.81% | +$4.08M |
| Compass Therapeutics, Inc.(CMPX) | 4,962,955 | 4,962,955 | 0 | $9.43M | $12.90M | 0.80% | +$3.47M |
| Spdr Series TrustS P BIOTECH ST STR SP BIOT | 0 | 151,750 | +151,750 | $0 | $12.58M | 0.78% | +$12.58M |
| Arcellx Inc COMMON STOCK | 0 | 186,314 | +186,314 | $0 | $12.27M | 0.76% | +$12.27M |
| Mereo BioPharma Group plcADS(MREO) | 6,684,247 | 4,465,292 | -2,218,955 | $15.04M | $12.10M | 0.75% | -$2.94M |
| Danaher Corporation(DHR) | 58,800 | 59,000 | +200 | $12.05M | $11.65M | 0.73% | -$399.1K |
| Amicus Therapeutics Inc COM | 1,909,362 | 1,960,334 | +50,972 | $15.58M | $11.23M | 0.70% | -$4.35M |
| West Pharmaceutical Services, Inc.(WST) | 60,250 | 51,030 | -9,220 | $13.49M | $11.17M | 0.70% | -$2.32M |
| Neurocrine Biosciences, Inc.(NBIX) | 279,000 | 88,800 | -190,200 | $30.86M | $11.16M | 0.70% | -$19.70M |
| Pharvaris N V COM | 623,402 | 623,402 | 0 | $9.79M | $10.97M | 0.68% | +$1.18M |
| Edwards Lifesciences Corp | 255,000 | 131,000 | -124,000 | $18.48M | $10.25M | 0.64% | -$8.24M |
| Newamsterdam Pharma Company ORDINARY SHARES | 536,111 | 536,111 | 0 | $10.97M | $9.71M | 0.60% | -$1.27M |
| Ardelyx Inc | 1,604,975 | 2,286,273 | +681,298 | $7.88M | $8.96M | 0.56% | +$1.08M |
| Nuvalent Inc | 427,532 | 93,328 | -334,204 | $30.32M | $7.12M | 0.44% | -$23.20M |
| Aclaris Therapeutics, Inc.(ACRS) | 5,046,309 | 4,769,309 | -277,000 | $7.72M | $6.77M | 0.42% | -$948.4K |
| Cidara Therapeutics Inc | 0 | 134,133 | +134,133 | $0 | $6.53M | 0.41% | +$6.53M |
| Zenas BioPharma, Inc.(ZBIO) | 878,667 | 640,467 | -238,200 | $6.94M | $6.21M | 0.39% | -$735.3K |
| Regeneron Pharmaceuticals, Inc.(REGN) | 2,800 | 11,300 | +8,500 | $1.78M | $5.93M | 0.37% | +$4.16M |
| Cogent Biosciences, Inc.(COGT) | 0 | 800,199 | +800,199 | $0 | $5.75M | 0.36% | +$5.75M |
| Dyne Therapeutics, Inc.(DYN) | 524,499 | 580,998 | +56,499 | $5.49M | $5.53M | 0.34% | +$44.8K |
| Cullinan Therapeutics, Inc.(CGEM) | 644,633 | 668,233 | +23,600 | $4.88M | $5.03M | 0.31% | +$151.9K |
| Gossamer Bio, Inc.NOTE 5 000 6 0(GOSS) | 0 | 0 | 0 | $5.26M | $4.95M | 0.31% | -$308.3K |
| Janux Therapeutics, Inc.(JANX) | 204,466 | 210,266 | +5,800 | $5.52M | $4.86M | 0.30% | -$663.4K |
| Mineralys Therapeutics, Inc.(MLYS) | 320,813 | 324,513 | +3,700 | $5.09M | $4.39M | 0.27% | -$703.8K |
| Thermo Fisher Scientific Inc.(TMO) | 0 | 10,000 | +10,000 | $0 | $4.05M | 0.25% | +$4.05M |
| Gossamer Bio, Inc.(GOSS) | 3,266,960 | 3,266,960 | 0 | $3.59M | $4.02M | 0.25% | +$424.7K |
| Immunovant, Inc.(IMVT) | 975,803 | 221,500 | -754,303 | $16.68M | $3.54M | 0.22% | -$13.13M |
| Amylyx Pharmaceuticals, Inc.(AMLX) | 343,228 | 499,764 | +156,536 | $1.22M | $3.20M | 0.20% | +$1.99M |
| Bicara Therapeutics Inc | 336,070 | 336,070 | 0 | $4.38M | $3.12M | 0.19% | -$1.26M |
| Jasper Therapeutics, Inc.(JSPR) | 545,171 | 545,171 | 0 | $2.34M | $3.03M | 0.19% | +$681.5K |
| Prothena Corp PlcSHS SHS | 492,601 | 492,601 | 0 | $6.10M | $2.99M | 0.19% | -$3.11M |
| Alphatec Holdings, Inc.(ATEC) | 267,500 | 267,500 | 0 | $2.71M | $2.97M | 0.19% | +$256.8K |
| LENZ Therapeutics, Inc.(LENZ) | 83,082 | 83,982 | +900 | $2.14M | $2.46M | 0.15% | +$325.5K |
| EDAP TMS S.A.ADR(FOCL) | 1,270,000 | 1,270,000 | 0 | $2.49M | $2.10M | 0.13% | -$393.7K |
| Compugen Ltd.(CGEN) | 989,990 | 989,990 | 0 | $1.45M | $1.76M | 0.11% | +$316.8K |
| Sionna Therapeutics, Inc.(SION) | 99,429 | 99,429 | 0 | $1.04M | $1.73M | 0.11% | +$685.1K |
| Pulmonx Corporation(LUNG) | 503,700 | 651,100 | +147,400 | $3.39M | $1.69M | 0.11% | -$1.70M |
| Neurogene Inc.(NGNE) | 104,339 | 104,339 | 0 | $1.22M | $1.56M | 0.10% | +$338.1K |
| Perspective Therapeutics, Inc.(CATX) | 444,383 | 444,383 | 0 | $946.5K | $1.53M | 0.10% | +$582.1K |
| Apellis Pharmaceuticals Inc COM | 80,000 | 84,300 | +4,300 | $1.75M | $1.46M | 0.09% | -$290.4K |
| Sarepta Therapeutics, Inc.(SRPT) | 159,300 | 68,600 | -90,700 | $10.17M | $1.17M | 0.07% | -$8.99M |
| Mersana Therapeutics Inc | 3,814,684 | 3,814,684 | 0 | $1.31M | $1.13M | 0.07% | -$183.9K |
| Applied Therapeutics Inc | 2,074,891 | 2,075,991 | +1,100 | $1.01M | $645.8K | 0.04% | -$368.6K |
| Adaptimmune Therapeutics plcADS(ADAPY) | 2,483,468 | 2,483,468 | 0 | $489.2K | $595.3K | 0.04% | +$106.0K |
| Korro Bio, Inc.(KRRO) | 35,719 | 35,719 | 0 | $621.9K | $446.1K | 0.03% | -$175.7K |
| Charles River Laboratories International, Inc.(CRL) | 0 | 2,700 | +2,700 | $0 | $409.7K | 0.03% | +$409.7K |
| 89bio Inc | 844,441 | 40,000 | -804,441 | $6.14M | $392.8K | 0.02% | -$5.75M |
| Vaxcyte, Inc.(PCVX) | 0 | 11,100 | +11,100 | $0 | $360.9K | 0.02% | +$360.9K |
| Novavax, Inc.(NVAX) | 650,000 | 53,900 | -596,100 | $4.17M | $339.6K | 0.02% | -$3.83M |
| Talphera, Inc.(TLPH) | 316,460 | 316,460 | 0 | $156.6K | $145.6K | 0.01% | -$11.0K |
| Nuvation Bio Inc.W EXP 02 10 202(NUVB) | 134,028 | 134,028 | 0 | $32.0K | $36.2K | 0.00% | +$4.2K |
| Beam Therapeutics Inc.(BEAM) | 150,020 | 0 | -150,020 | $2.93M | $0 | — | -$2.93M |
| BioCryst Pharmaceuticals, Inc.(BCRX) | 222,011 | 0 | -222,011 | $1.67M | $0 | — | -$1.67M |
| Inozyme Pharma Inc | 3,445,299 | 0 | -3,445,299 | $3.14M | $0 | — | -$3.14M |
| Kestra Med Technologies LtdSHS SHS | 145,000 | 0 | -145,000 | $3.61M | $0 | — | -$3.61M |
| Legend Biotech CorporationADS(LEGN) | 512,932 | 0 | -512,932 | $17.40M | $0 | — | -$17.40M |
| MacroGenics, Inc.(MGNX) | 1,145,214 | 0 | -1,145,214 | $1.45M | $0 | — | -$1.45M |
| Nevro Corp | 800,494 | 0 | -800,494 | $4.67M | $0 | — | -$4.67M |