Securities ▲▼ | Shares | Value ($K) | |||||
|---|---|---|---|---|---|---|---|
Q1 2026 ▲▼ | Q2 2026 ▲▼ | Change ▲▼ | Q1 2026 ▲▼ | Q2 2026 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| REVOLUTION MEDICINES INC(RVMD) | 1,209,465 | 1,105,210 | -104,255 | 117,620 | 206,984 | 10.10% | +89,363 |
| TRAVERE THERAPEUTICS INC(TVTX) | 0 | 2,179,069 | +2,179,069 | 0 | 123,793 | 6.04% | +123,793 |
| ASCENDIS PHARMA A/S(ASND) | 0 | 168,750 | +168,750 | 0 | 45,009 | 2.20% | +45,009 |
| ELI LILLY & CO(LLY) | 0 | 98,700 | +98,700 | 0 | 118,384 | 5.78% | +118,384 |
| AGILON HEALTH INC(AGL) | 260,000 | 262,600 | +2,600 | 2,057 | 28,145 | 1.37% | +26,089 |
| AVALYN PHARMACEUTICALS INC | 0 | 662,918 | +662,918 | 0 | 21,823 | 1.07% | +21,823 |
| HEMAB THERAPEUTICS HLDGS INC | 0 | 575,432 | +575,432 | 0 | 21,136 | 1.03% | +21,136 |
| MIRUM PHARMACEUTICALS INC(MIRM) | 811,294 | 798,145 | -13,149 | 74,947 | 93,439 | 4.56% | +18,491 |
| RHYTHM PHARMACEUTICALS INC(RYTM) | 0 | 692,598 | +692,598 | 0 | 76,899 | 3.75% | +76,899 |
| PARABILIS MEDICINES INC | 0 | 578,028 | +578,028 | 0 | 15,821 | 0.77% | +15,821 |
| CYTOKINETICS INC(CYTK) | 45,364 | 187,980 | +142,616 | 2,990 | 16,014 | 0.78% | +13,024 |
| UNITEDHEALTH GROUP INC(UNH) | 53,000 | 63,750 | +10,750 | 14,341 | 26,496 | 1.29% | +12,155 |
| KYMERA THERAPEUTICS INC(KYMR) | 496,871 | 453,156 | -43,715 | 41,384 | 51,963 | 2.54% | +10,579 |
| MBX BIOSCIENCES INC(MBX) | 287,967 | 298,218 | +10,251 | 8,596 | 16,462 | 0.80% | +7,866 |
| ERASCA INC(ERAS) | 1,103,469 | 1,402,150 | +298,681 | 17,854 | 25,687 | 1.25% | +7,833 |
| EVOLENT HEALTH INC | 2,675,000 | 2,500,000 | -175,000 | 6,099 | 13,550 | 0.66% | +7,451 |
| MINIMED GROUP INC(MMED) | 1,055,000 | 1,520,000 | +465,000 | 15,741 | 22,724 | 1.11% | +6,983 |
| OMEROS CORP(OMER) | 0 | 718,499 | +718,499 | 0 | 6,833 | 0.33% | +6,833 |
| ULTRAGENYX PHARMACEUTICAL IN(RARE) | 1,218,773 | 967,855 | -250,918 | 25,533 | 32,317 | 1.58% | +6,783 |
| DEFINIUM THERAPEUTICS INC(DFTX) | 0 | 143,187 | +143,187 | 0 | 6,736 | 0.33% | +6,736 |
| TANGO THERAPEUTICS INC(TNGX) | 386,915 | 456,551 | +69,636 | 8,094 | 14,272 | 0.70% | +6,178 |
| BICARA THERAPEUTICS INC | 489,095 | 535,286 | +46,191 | 9,728 | 15,893 | 0.78% | +6,165 |
| ACLARIS THERAPEUTICS INC(ACRS) | 4,472,650 | 4,330,532 | -142,118 | 16,772 | 22,909 | 1.12% | +6,136 |
| MOBIA MED INC | 0 | 418,200 | +418,200 | 0 | 5,604 | 0.27% | +5,604 |
| CELLDEX THERAPEUTICS INC NEW(CLDX) | 650,270 | 699,146 | +48,876 | 20,627 | 26,015 | 1.27% | +5,389 |
| TREVI THERAPEUTICS INC(TRVI) | 0 | 260,000 | +260,000 | 0 | 4,849 | 0.24% | +4,849 |
| NEUROCRINE BIOSCIENCES INC(NBIX) | 150,450 | 144,750 | -5,700 | 19,820 | 24,395 | 1.19% | +4,575 |
| MADRIGAL PHARMACEUTICALS INC(MDGL) | 170,999 | 174,999 | +4,000 | 89,513 | 93,966 | 4.59% | +4,453 |
| STRYKER CORPORATION(SYK) | 14,800 | 29,000 | +14,200 | 4,863 | 9,130 | 0.45% | +4,267 |
| CORCEPT THERAPEUTICS INC(CORT) | 50,250 | 72,000 | +21,750 | 2,026 | 6,260 | 0.31% | +4,235 |
| PHARVARIS N V COM | 645,533 | 648,333 | +2,800 | 18,236 | 22,419 | 1.09% | +4,183 |
| INSPIRE MED SYS INC(INSP) | 131,800 | 244,000 | +112,200 | 6,798 | 10,885 | 0.53% | +4,087 |
| INDIVIOR PHARMACEUTICALS INC(INDV) | 200,000 | 245,500 | +45,500 | 6,096 | 10,073 | 0.49% | +3,977 |
| ALKERMES PLC(ALKS) | 183,986 | 199,811 | +15,825 | 6,506 | 10,469 | 0.51% | +3,963 |
| SPYRE THERAPEUTICS INC(SYRE) | 0 | 42,254 | +42,254 | 0 | 3,751 | 0.18% | +3,751 |
| STRUCTURE THERAPEUTICS INC | 0 | 640,317 | +640,317 | 0 | 34,366 | 1.68% | +34,366 |
| DYNE THERAPEUTICS INC(DYN) | 972,198 | 942,154 | -30,044 | 17,626 | 20,925 | 1.02% | +3,299 |
| SCHOLAR ROCK HLDG CORP(SRRK) | 739,816 | 715,452 | -24,364 | 36,369 | 39,350 | 1.92% | +2,981 |
| ZENAS BIOPHARMA INC(ZBIO) | 502,077 | 502,077 | 0 | 9,816 | 12,743 | 0.62% | +2,927 |
| HEARTFLOW INC(HTFL) | 572,500 | 573,500 | +1,000 | 13,929 | 16,826 | 0.82% | +2,898 |
| DANAHER CORP DEL(DHR) | 61,500 | 76,300 | +14,800 | 11,660 | 14,534 | 0.71% | +2,873 |
| NERVGEN PHARMA CORP | 0 | 1,208,231 | +1,208,231 | 0 | 2,489 | 0.12% | +2,489 |
| MEDTRONIC PLC(MDT) | 0 | 30,900 | +30,900 | 0 | 2,417 | 0.12% | +2,417 |
| PTC THERAPEUTICS INC(PTCT) | 161,798 | 162,298 | +500 | 11,023 | 13,239 | 0.65% | +2,215 |
| PHREESIA INC | 600,400 | 696,900 | +96,500 | 5,031 | 7,171 | 0.35% | +2,140 |
| EDAP TMS S A | 1,378,000 | 1,386,000 | +8,000 | 5,126 | 7,179 | 0.35% | +2,053 |
| AMYLYX PHARMACEUTICALS INC(AMLX) | 499,764 | 499,764 | 0 | 6,947 | 8,976 | 0.44% | +2,029 |
| SAGIMET BIOSCIENCES INC | 0 | 250,000 | +250,000 | 0 | 1,933 | 0.09% | +1,933 |
| CAPRICOR THERAPEUTICS INC | 0 | 74,448 | +74,448 | 0 | 1,793 | 0.09% | +1,793 |
| ARCUS BIOSCIENCES INC(RCUS) | 180,000 | 180,000 | 0 | 3,888 | 5,549 | 0.27% | +1,661 |
| TARSUS PHARMACEUTICALS INC(TARS) | 225,179 | 277,087 | +51,908 | 15,796 | 17,440 | 0.85% | +1,644 |
| ALTIMMUNE INC | 0 | 471,465 | +471,465 | 0 | 1,433 | 0.07% | +1,433 |
| KAILERA THERAPEUTICS INC | 0 | 65,000 | +65,000 | 0 | 1,432 | 0.07% | +1,432 |
| OMADA HEALTH INC(OMDA) | 541,000 | 373,000 | -168,000 | 6,800 | 8,187 | 0.40% | +1,387 |
| AXSOME THERAPEUTICS INC.(AXSM) | 0 | 5,500 | +5,500 | 0 | 1,346 | 0.07% | +1,346 |
| CVS HEALTH CORP(CVS) | 40,000 | 40,000 | 0 | 2,873 | 4,138 | 0.20% | +1,265 |
| BRIDGEBIO PHARMA INC(BBIO) | 128,250 | 144,750 | +16,500 | 9,524 | 10,781 | 0.53% | +1,257 |
| NEUROGENE INC | 104,339 | 106,750 | +2,411 | 2,103 | 3,357 | 0.16% | +1,254 |
| IRHYTHM HOLDINGS INC(IRTC) | 0 | 269,650 | +269,650 | 0 | 32,075 | 1.57% | +32,075 |
| MINERALYS THERAPEUTICS INC(MLYS) | 439,751 | 484,951 | +45,200 | 11,913 | 13,084 | 0.64% | +1,171 |
| TALPHERA INC | 3,589,186 | 3,589,186 | 0 | 2,681 | 3,697 | 0.18% | +1,016 |
| ORUKA THERAPEUTICS INC(ORKA) | 4,123 | 12,051 | +7,928 | 202 | 1,147 | 0.06% | +945 |
| NEWAMSTERDAM PHARMA COMPANY ORDINARY SHARES | 588,794 | 582,744 | -6,050 | 18,847 | 19,749 | 0.96% | +902 |
| ROIVANT SCIENCES LTD(ROIV) | 97,000 | 101,000 | +4,000 | 2,687 | 3,574 | 0.17% | +887 |
| DEXCOM INC(DXCM) | 355,600 | 343,000 | -12,600 | 22,332 | 23,101 | 1.13% | +769 |
| GLAUKOS CORP(GKOS) | 0 | 4,750 | +4,750 | 0 | 664 | 0.03% | +664 |
| TEVA PHARMACEUTICAL INDS LTD(TEVA) | 45,500 | 59,000 | +13,500 | 1,370 | 1,999 | 0.10% | +628 |
| JANUX THERAPEUTICS INC(JANX) | 367,009 | 367,009 | 0 | 5,101 | 5,637 | 0.28% | +536 |
| OCULAR THERAPEUTIX INC(OCUL) | 383,716 | 383,716 | 0 | 3,250 | 3,768 | 0.18% | +518 |
| EYEPOINT INC(EYPT) | 258,739 | 268,519 | +9,780 | 3,335 | 3,840 | 0.19% | +505 |
| OLEMA PHARMACEUTICALS INC(OLMA) | 170,378 | 235,178 | +64,800 | 2,540 | 2,942 | 0.14% | +402 |
| SIONNA THERAPEUTICS INC | 99,429 | 99,429 | 0 | 3,986 | 4,374 | 0.21% | +388 |
| CENTURY THERAPEUTICS INC | 1,304,347 | 1,304,347 | 0 | 2,948 | 3,196 | 0.16% | +248 |
| LEGEND BIOTECH CORP(LEGN) | 40,500 | 33,500 | -7,000 | 733 | 967 | 0.05% | +235 |
| ZAI LAB LTD(ZLAB) | 814,707 | 814,707 | 0 | 15,325 | 15,479 | 0.76% | +155 |
| BIOCRYST PHARMACEUTICALS INC(BCRX) | 12,600 | 22,124 | +9,524 | 120 | 221 | 0.01% | +101 |
| THERMO FISHER SCIENTIFIC INC(TMO) | 10,000 | 10,000 | 0 | 4,915 | 5,014 | 0.24% | +98 |
| VAXCYTE INC(PCVX) | 60,250 | 60,250 | 0 | 3,501 | 3,502 | 0.17% | +1 |
| TENET HEALTHCARE CORP(THC) | 125,000 | 125,000 | 0 | 23,589 | 23,385 | 1.14% | -204 |
| IMMUNOME INC(IMNM) | 347,666 | 347,666 | 0 | 7,603 | 7,367 | 0.36% | -236 |
| NOVO-NORDISK A S(NVO) | 90,000 | 63,500 | -26,500 | 3,308 | 3,044 | 0.15% | -263 |
| DIANTHUS THERAPEUTICS INC(DNTH) | 26,757 | 20,326 | -6,431 | 2,245 | 1,981 | 0.10% | -264 |
| AMICUS THERAPEUTIC COM | 0 | 0 | 0 | 0 | 0 | — | 0 |
| JASPER THERAPEUTICS INC | 1,100,726 | 1,100,726 | 0 | 964 | 463 | 0.02% | -501 |
| GOSSAMER BIO INC | 1,609,492 | 0 | -1,609,492 | 529 | 0 | — | -529 |
| ALPHATEC HLDGS INC(ATEC) | 350,000 | 360,000 | +10,000 | 3,808 | 3,114 | 0.15% | -694 |
| LENZ THERAPEUTICS INC | 257,460 | 257,460 | 0 | 2,356 | 1,462 | 0.07% | -893 |
| MOONLAKE IMMUNOTHERAPEUTICS(MLTX) | 61,700 | 10,696 | -51,004 | 1,150 | 208 | 0.01% | -942 |
| SURGERY PARTNERS INC(SGRY) | 208,000 | 84,000 | -124,000 | 2,479 | 1,411 | 0.07% | -1,068 |
| JAZZ PHARMACEUTICALS PLC(JAZZ) | 5,750 | 0 | -5,750 | 1,087 | 0 | — | -1,087 |
| CARIS LIFE SCIENCES INC(CAI) | 563,000 | 487,500 | -75,500 | 10,066 | 8,687 | 0.42% | -1,379 |
| AZENTA INC(AZTA) | 569,100 | 403,000 | -166,100 | 12,025 | 10,285 | 0.50% | -1,741 |
| ACADIA HEALTHCARE COMPANY IN(ACHC) | 75,500 | 0 | -75,500 | 1,766 | 0 | — | -1,766 |
| VERA THERAPEUTICS INC(VERA) | 503,585 | 427,584 | -76,001 | 20,259 | 18,348 | 0.90% | -1,912 |
| VIKING THERAPEUTICS INC(VKTX) | 96,000 | 25,500 | -70,500 | 3,124 | 995 | 0.05% | -2,129 |
| EDWARDS LIFESCIENCES CORP | 28,900 | 0 | -28,900 | 2,314 | 0 | — | -2,314 |
| ARDELYX INC | 2,299,473 | 2,241,769 | -57,704 | 13,774 | 11,433 | 0.56% | -2,341 |
| PENUMBRA INC(PEN) | 120,500 | 115,750 | -4,750 | 39,569 | 36,548 | 1.78% | -3,021 |
| SUMMIT THERAPEUTICS INC(SMMT) | 710,000 | 715,000 | +5,000 | 13,462 | 10,418 | 0.51% | -3,044 |
| XENON PHARMACEUTICALS INC(XENE) | 763,020 | 683,907 | -79,113 | 44,370 | 41,281 | 2.01% | -3,089 |