Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q2 2025 ▲▼ | Q3 2025 ▲▼ | Change ▲▼ | Q2 2025 ▲▼ | Q3 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| argenx SEADR(ARGX) | 175,750 | 142,750 | -33,000 | $96.88M | $105.29M | 6.15% | +$8.41M |
| Eli Lilly and Company(LLY) | 116,500 | 105,400 | -11,100 | $90.82M | $80.42M | 4.70% | -$10.40M |
| Rhythm Pharmaceuticals, Inc.(RYTM) | 861,153 | 717,102 | -144,051 | $54.42M | $72.42M | 4.23% | +$18.00M |
| Madrigal Pharmaceuticals, Inc.(MDGL) | 140,296 | 137,746 | -2,550 | $42.46M | $63.18M | 3.69% | +$20.72M |
| Revolution Medicines, Inc.(RVMD) | 1,330,960 | 1,335,270 | +4,310 | $48.97M | $62.36M | 3.65% | +$13.39M |
| Merus N V | 1,063,608 | 597,051 | -466,557 | $55.95M | $56.21M | 3.29% | +$266.6K |
| Mirum Pharmaceuticals, Inc.(MIRM) | 818,206 | 761,126 | -57,080 | $41.64M | $55.80M | 3.26% | +$14.16M |
| Insmed Incorporated(INSM) | 525,000 | 385,000 | -140,000 | $52.84M | $55.44M | 3.24% | +$2.61M |
| Travere Therapeutics, Inc.(TVTX) | 1,908,208 | 2,164,773 | +256,565 | $28.24M | $51.74M | 3.02% | +$23.50M |
| Ascendis Pharma A/SADR(ASND) | 217,000 | 214,500 | -2,500 | $37.45M | $42.64M | 2.49% | +$5.19M |
| iRhythm Holdings, Inc.(IRTC) | 242,500 | 235,000 | -7,500 | $37.34M | $40.42M | 2.36% | +$3.08M |
| Agios Pharmaceuticals, Inc.(AGIO) | 989,745 | 958,542 | -31,203 | $32.92M | $38.48M | 2.25% | +$5.56M |
| Ultragenyx Pharmaceutical Inc.(RARE) | 1,391,072 | 1,246,341 | -144,731 | $50.58M | $37.49M | 2.19% | -$13.09M |
| Intuitive Surgical, Inc.(ISRG) | 82,000 | 82,000 | 0 | $44.56M | $36.67M | 2.14% | -$7.89M |
| Boston Scientific Corporation(BSX) | 355,000 | 360,250 | +5,250 | $38.13M | $35.17M | 2.06% | -$2.96M |
| Xenon Pharmaceuticals Inc.(XENE) | 931,681 | 851,744 | -79,937 | $29.16M | $34.20M | 2.00% | +$5.04M |
| Alnylam Pharmaceuticals, Inc.(ALNY) | 100,000 | 74,250 | -25,750 | $32.61M | $33.86M | 1.98% | +$1.25M |
| Endeavour Silver Corp.(EXK) | 572,000 | 593,500 | +21,500 | $30.40M | $32.47M | 1.90% | +$2.07M |
| Penumbra, Inc.(PEN) | 128,500 | 120,500 | -8,000 | $32.98M | $30.53M | 1.78% | -$2.45M |
| Akero Therapeutics Inc | 640,526 | 626,526 | -14,000 | $34.18M | $29.75M | 1.74% | -$4.43M |
| Scholar Rock Holding Corporation(SRRK) | 794,133 | 794,133 | 0 | $28.13M | $29.57M | 1.73% | +$1.45M |
| Zai Lab LimitedADR(ZLAB) | 871,392 | 791,193 | -80,199 | $30.47M | $26.81M | 1.57% | -$3.66M |
| Structure Therapeutics IncADS | 1,135,879 | 951,154 | -184,725 | $23.56M | $26.63M | 1.56% | +$3.07M |
| Kymera Therapeutics, Inc.(KYMR) | 450,374 | 450,374 | 0 | $19.65M | $25.49M | 1.49% | +$5.84M |
| Tenet Healthcare Corporation(THC) | 130,000 | 125,000 | -5,000 | $22.88M | $25.38M | 1.48% | +$2.50M |
| Evolent Health, Inc.CL A(EVH) | 2,820,700 | 2,950,000 | +129,300 | $31.76M | $24.96M | 1.46% | -$6.80M |
| Caris Life Sciences, Inc.(CAI) | 793,651 | 793,651 | 0 | $21.21M | $24.01M | 1.40% | +$2.80M |
| Cidara Therapeutics Inc | 134,133 | 249,402 | +115,269 | $6.53M | $23.88M | 1.40% | +$17.35M |
| DexCom, Inc.(DXCM) | 286,750 | 316,900 | +30,150 | $25.03M | $21.32M | 1.25% | -$3.71M |
| Omada Health, Inc.(OMDA) | 919,951 | 919,950 | -1 | $16.84M | $20.34M | 1.19% | +$3.50M |
| Celldex Therapeutics, Inc.(CLDX) | 812,653 | 721,538 | -91,115 | $16.54M | $18.67M | 1.09% | +$2.13M |
| Vera Therapeutics, Inc.CL A(VERA) | 617,396 | 617,396 | 0 | $14.55M | $17.94M | 1.05% | +$3.40M |
| Phreesia, Inc.(PHR) | 837,300 | 749,116 | -88,184 | $23.83M | $17.62M | 1.03% | -$6.21M |
| Tarsus Pharmaceuticals, Inc.(TARS) | 373,750 | 288,344 | -85,406 | $15.14M | $17.14M | 1.00% | +$2.00M |
| Newamsterdam Pharma Company ORDINARY SHARES | 536,111 | 595,929 | +59,818 | $9.71M | $16.95M | 0.99% | +$7.24M |
| Compass Therapeutics, Inc.(CMPX) | 4,962,955 | 4,474,702 | -488,253 | $12.90M | $15.66M | 0.92% | +$2.76M |
| Pharvaris N V COM | 623,402 | 623,402 | 0 | $10.97M | $15.55M | 0.91% | +$4.58M |
| Azenta, Inc.(AZTA) | 530,400 | 540,400 | +10,000 | $16.33M | $15.52M | 0.91% | -$805.4K |
| Mineralys Therapeutics, Inc.(MLYS) | 324,513 | 408,313 | +83,800 | $4.39M | $15.48M | 0.91% | +$11.09M |
| Amicus Therapeutics Inc COM | 1,960,334 | 1,947,374 | -12,960 | $11.23M | $15.35M | 0.90% | +$4.11M |
| Spdr Series TrustS P BIOTECH ST STR SP BIOT | 151,750 | 151,750 | 0 | $12.58M | $15.21M | 0.89% | +$2.62M |
| Arcellx Inc COMMON STOCK | 186,314 | 178,982 | -7,332 | $12.27M | $14.69M | 0.86% | +$2.43M |
| Summit Therapeutics Inc.(SMMT) | 710,000 | 710,000 | 0 | $15.11M | $14.67M | 0.86% | -$440.2K |
| Cogent Biosciences, Inc.(COGT) | 800,199 | 1,008,308 | +208,109 | $5.75M | $14.48M | 0.85% | +$8.73M |
| Enliven Therapeutics Inc | 701,408 | 686,107 | -15,301 | $14.07M | $14.04M | 0.82% | -$25.6K |
| Zenas BioPharma, Inc.(ZBIO) | 640,467 | 580,677 | -59,790 | $6.21M | $12.89M | 0.75% | +$6.68M |
| Neurocrine Biosciences, Inc.(NBIX) | 88,800 | 89,750 | +950 | $11.16M | $12.60M | 0.74% | +$1.44M |
| Ardelyx Inc | 2,286,273 | 2,286,273 | 0 | $8.96M | $12.60M | 0.74% | +$3.64M |
| Danaher Corporation(DHR) | 59,000 | 61,500 | +2,500 | $11.65M | $12.19M | 0.71% | +$538.1K |
| LENZ Therapeutics, Inc.(LENZ) | 83,982 | 236,227 | +152,245 | $2.46M | $11.00M | 0.64% | +$8.54M |
| Soleno Therapeutics Inc | 154,528 | 154,528 | 0 | $12.95M | $10.45M | 0.61% | -$2.50M |
| Dyne Therapeutics, Inc.(DYN) | 580,998 | 824,061 | +243,063 | $5.53M | $10.42M | 0.61% | +$4.89M |
| Mereo BioPharma Group plcADS(MREO) | 4,465,292 | 4,570,649 | +105,357 | $12.10M | $9.42M | 0.55% | -$2.69M |
| Aclaris Therapeutics, Inc.(ACRS) | 4,769,309 | 4,609,309 | -160,000 | $6.77M | $8.76M | 0.51% | +$1.99M |
| Gossamer Bio, Inc.(GOSS) | 3,266,960 | 3,266,960 | 0 | $4.02M | $8.59M | 0.50% | +$4.57M |
| Heartflow, Inc.(HTFL) | 0 | 250,000 | +250,000 | $0 | $8.41M | 0.49% | +$8.41M |
| Inspire Medical Systems, Inc.(INSP) | 107,500 | 110,500 | +3,000 | $13.95M | $8.20M | 0.48% | -$5.75M |
| agilon health, inc.(AGL) | 6,550,400 | 6,966,300 | +415,900 | $15.07M | $7.18M | 0.42% | -$7.89M |
| Edwards Lifesciences Corp | 131,000 | 88,000 | -43,000 | $10.25M | $6.84M | 0.40% | -$3.40M |
| Amylyx Pharmaceuticals, Inc.(AMLX) | 499,764 | 499,764 | 0 | $3.20M | $6.79M | 0.40% | +$3.59M |
| Gossamer Bio, Inc.NOTE 5 000 6 0(GOSS) | 0 | 0 | 0 | $4.95M | $6.72M | 0.39% | +$1.77M |
| Regeneron Pharmaceuticals, Inc.(REGN) | 11,300 | 11,300 | 0 | $5.93M | $6.35M | 0.37% | +$421.2K |
| Bicara Therapeutics Inc | 336,070 | 370,666 | +34,596 | $3.12M | $5.85M | 0.34% | +$2.73M |
| Janux Therapeutics, Inc.(JANX) | 210,266 | 210,366 | +100 | $4.86M | $5.14M | 0.30% | +$284.2K |
| MBX Biosciences, Inc.(MBX) | 0 | 282,624 | +282,624 | $0 | $4.95M | 0.29% | +$4.95M |
| Thermo Fisher Scientific Inc.(TMO) | 10,000 | 10,000 | 0 | $4.05M | $4.85M | 0.28% | +$795.6K |
| BridgeBio Pharma, Inc.(BBIO) | 0 | 85,000 | +85,000 | $0 | $4.41M | 0.26% | +$4.41M |
| Alphatec Holdings, Inc.(ATEC) | 267,500 | 302,500 | +35,000 | $2.97M | $4.40M | 0.26% | +$1.43M |
| Acadia Healthcare Company, Inc.(ACHC) | 696,000 | 170,000 | -526,000 | $15.79M | $4.21M | 0.25% | -$11.58M |
| Ocular Therapeutix, Inc.(OCUL) | 0 | 300,000 | +300,000 | $0 | $3.51M | 0.21% | +$3.51M |
| Talphera, Inc.(TLPH) | 316,460 | 3,589,186 | +3,272,726 | $145.6K | $3.21M | 0.19% | +$3.06M |
| Alkermes plcSHS(ALKS) | 0 | 106,537 | +106,537 | $0 | $3.20M | 0.19% | +$3.20M |
| Sionna Therapeutics, Inc.(SION) | 99,429 | 99,429 | 0 | $1.73M | $2.92M | 0.17% | +$1.20M |
| EDAP TMS S.A.ADR(FOCL) | 1,270,000 | 1,270,000 | 0 | $2.10M | $2.91M | 0.17% | +$812.8K |
| Jasper Therapeutics, Inc.(JSPR) | 545,171 | 1,100,726 | +555,555 | $3.03M | $2.62M | 0.15% | -$406.0K |
| West Pharmaceutical Services, Inc.(WST) | 51,030 | 9,750 | -41,280 | $11.17M | $2.56M | 0.15% | -$8.61M |
| Apellis Pharmaceuticals Inc COM | 84,300 | 92,000 | +7,700 | $1.46M | $2.08M | 0.12% | +$622.7K |
| Neurogene Inc.(NGNE) | 104,339 | 104,339 | 0 | $1.56M | $1.81M | 0.11% | +$248.3K |
| Korro Bio, Inc.(KRRO) | 35,719 | 35,719 | 0 | $446.1K | $1.71M | 0.10% | +$1.26M |
| Centessa Pharmaceuticals PlcADS | 0 | 69,240 | +69,240 | $0 | $1.68M | 0.10% | +$1.68M |
| Perspective Therapeutics, Inc.(CATX) | 444,383 | 444,383 | 0 | $1.53M | $1.52M | 0.09% | -$4.4K |
| Applied Therapeutics Inc | 2,075,991 | 2,075,991 | 0 | $645.8K | $1.26M | 0.07% | +$609.9K |
| Mersana Therapeutics Inc | 0 | 152,586 | +152,586 | $0 | $1.18M | 0.07% | +$1.18M |
| Immunovant, Inc.(IMVT) | 221,500 | 72,965 | -148,535 | $3.54M | $1.18M | 0.07% | -$2.37M |
| EyePoint, Inc.(EYPT) | 0 | 31,655 | +31,655 | $0 | $450.8K | 0.03% | +$450.8K |
| Charles River Laboratories International, Inc.(CRL) | 2,700 | 2,700 | 0 | $409.7K | $422.4K | 0.02% | +$12.8K |
| Vaxcyte, Inc.(PCVX) | 11,100 | 11,100 | 0 | $360.9K | $399.8K | 0.02% | +$39.0K |
| Novavax, Inc.(NVAX) | 53,900 | 45,000 | -8,900 | $339.6K | $390.1K | 0.02% | +$50.6K |
| Prothena Corp PlcSHS SHS | 492,601 | 25,398 | -467,203 | $2.99M | $247.9K | 0.01% | -$2.74M |
| MoonLake ImmunotherapeuticsCL A(MLTX) | 0 | 28,200 | +28,200 | $0 | $202.2K | 0.01% | +$202.2K |
| Nuvation Bio Inc.W EXP 02 10 202(NUVB) | 134,028 | 134,028 | 0 | $36.2K | $27.1K | 0.00% | -$9.1K |
| Compugen Ltd.(CGEN) | 989,990 | 13,430 | -976,560 | $1.76M | $19.7K | 0.00% | -$1.74M |
| 89bio Inc | 40,000 | 0 | -40,000 | $392.8K | $0 | — | -$392.8K |
| Adaptimmune Therapeutics plcADS(ADAPY) | 2,483,468 | 0 | -2,483,468 | $595.3K | $0 | — | -$595.3K |
| Blueprint Medicines Corp | 185,500 | 0 | -185,500 | $23.78M | $0 | — | -$23.78M |
| Cullinan Therapeutics, Inc.(CGEM) | 668,233 | 0 | -668,233 | $5.03M | $0 | — | -$5.03M |
| Mersana Therapeutics Inc | 3,814,684 | 0 | -3,814,684 | $1.13M | $0 | — | -$1.13M |
| Nuvalent Inc | 93,328 | 0 | -93,328 | $7.12M | $0 | — | -$7.12M |
| Oscar Health, Inc.CL A(OSCR) | 700,000 | 0 | -700,000 | $15.01M | $0 | — | -$15.01M |
| Pulmonx Corporation(LUNG) | 651,100 | 0 | -651,100 | $1.69M | $0 | — | -$1.69M |