Fund Holdings — Opaleye Management Inc.

Total Portfolio Value:
$437.66M
Total Bought:
$97.62M
Total Sold:
$102.32M
Net Transaction:
-$4.70M
Notable People:
James Aaron Silverman
Securities
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SharesValue
Q1 2024
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Q2 2024
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Change
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Q1 2024
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Q2 2024
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Weight (%)
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Change
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Harrow, Inc.(HROW)3,920,6003,990,000+69,400$51.87M$83.35M19.04%+$31.48M
TG Therapeutics, Inc.(TGTX)2,280,0002,280,0000$34.68M$40.56M9.27%+$5.88M
Ocular Therapeutix, Inc.(OCUL)6,653,1385,307,500-1,345,638$60.54M$36.30M8.29%-$24.24M
Rhythm Pharmaceuticals, Inc.(RYTM)515,000515,0000$22.31M$21.15M4.83%-$1.17M
Keros Therapeutics, Inc.(KROS)367,500367,5000$24.33M$16.79M3.84%-$7.53M
Arvinas, Inc.(ARVN)330,000555,000+225,000$13.62M$14.77M3.38%+$1.15M
Immunome, Inc.(IMNM)01,102,500+1,102,500$0$13.34M3.05%+$13.34M
Cytokinetics, Incorporated(CYTK)0198,500+198,500$0$10.75M2.46%+$10.75M
Codexis, Inc.(CDXS)3,120,0003,455,000+335,000$10.89M$10.71M2.45%-$178.3K
Edgewise Therapeutics, Inc.(EWTX)665,000580,000-85,000$12.13M$10.45M2.39%-$1.68M
Catalyst Pharmaceuticals Inc1,004,355640,000-364,355$16.01M$9.91M2.27%-$6.10M
Cargo Therapeutics Inc0555,700+555,700$0$9.12M2.08%+$9.12M
Jasper Therapeutics, Inc.(JSPR)435,573392,000-43,573$12.79M$8.90M2.03%-$3.89M
Nurix Therapeutics, Inc.(NRIX)267,210418,928+151,718$3.93M$8.74M2.00%+$4.82M
Trevi Therapeutics, Inc.(TRVI)2,645,0002,645,0000$9.13M$7.88M1.80%-$1.24M
Eton Pharmaceuticals, Inc.(ETON)2,445,7812,395,000-50,781$9.17M$7.88M1.80%-$1.29M
Applied Therapeutics Inc'1,770,0001,680,000-90,000$12.04M$7.85M1.79%-$4.19M
4d Molecular Therapeutics Inc344,123345,750+1,627$10.96M$7.26M1.66%-$3.71M
Iovance Biotherapeutics, Inc.(IOVA)897,000897,0000$13.29M$7.19M1.64%-$6.10M
Acelyrin Inc1,580,0001,580,0000$10.66M$6.97M1.59%-$3.70M
UroGen Pharma Ltd.(URGN)270,000412,000+142,000$4.05M$6.91M1.58%+$2.86M
Vaxcyte, Inc.(PCVX)85,00085,0000$5.81M$6.42M1.47%+$612.0K
Biodesix, Inc.(BDSX)534,6574,020,000+3,485,343$764.6K$6.15M1.41%+$5.39M
Newamsterdam Pharma Company
ORDINARY SHARES
315,388315,000-388$7.46M$6.05M1.38%-$1.41M
Xoma Corp Del250,000250,0000$6.01M$5.92M1.35%-$90.0K
Protara Therapeutics, Inc.(TARA)2,692,5942,304,262-388,332$10.80M$5.30M1.21%-$5.50M
Intellia Therapeutics, Inc.(NTLA)255,000218,000-37,000$7.02M$4.88M1.11%-$2.14M
Nuvalent Inc059,300+59,300$0$4.50M1.03%+$4.50M
Syros Pharmaceuticals Inc787,545865,443+77,898$4.21M$4.47M1.02%+$252.9K
Gossamer Bio, Inc.NOTE 5 000 6 0(GOSS)000$3.21M$3.96M0.90%+$744.8K
Liquidia Corporation(LQDA)395,000325,000-70,000$5.83M$3.90M0.89%-$1.93M
Karyopharm Therapeutics IncNOTE 3 000 10 1000$0$3.75M0.86%+$3.75M
Protagonist Therapeutics Inc112,700105,000-7,700$3.26M$3.64M0.83%+$377.8K
Gossamer Bio, Inc.(GOSS)2,440,1093,910,000+1,469,891$2.88M$3.52M0.80%+$643.2K
Lexicon Pharmaceuticals, Inc.(LXRX)01,875,000+1,875,000$0$3.15M0.72%+$3.15M
Savara Inc.(SVRA)855,000714,960-140,040$4.26M$2.88M0.66%-$1.38M
Allakos Inc2,435,0002,780,000+345,000$3.07M$2.78M0.64%-$288.1K
Ventyx Biosciences Inc1,285,0001,190,000-95,000$7.07M$2.75M0.63%-$4.32M
Verastem, Inc.(VSTM)211,400915,000+703,600$2.49M$2.73M0.62%+$232.2K
Regulus Therapeutics Inc170,3081,475,000+1,304,692$490.5K$2.63M0.60%+$2.14M
Lyell Immunopharma, Inc.(LYEL)3,355,0001,670,000-1,685,000$7.48M$2.42M0.55%-$5.06M
Relmada Therapeutics, Inc.(RLMD)759,000600,000-159,000$3.53M$1.80M0.41%-$1.73M
Fulcrum Therapeutics, Inc.(FULC)130,000285,000+155,000$1.23M$1.77M0.40%+$539.8K
Karyopharm Therapeutics Inc.(KPTI)01,425,000+1,425,000$0$1.24M0.28%+$1.24M
iBio, Inc.(IBIO)680,000375,000-305,000$2.76M$791.3K0.18%-$1.97M
PMV Pharmaceuticals, Inc.(PMVP)471,481475,000+3,519$802.1K$769.5K0.18%-$32.6K
Aerovate Therapeutics Inc0440,000+440,000$0$730.4K0.17%+$730.4K
Design Therapeutics, Inc.(DSGN)113,038205,000+91,962$455.5K$686.8K0.16%+$231.2K
AbCellera Biologics Inc.(ABCL)0200,000+200,000$0$592.0K0.14%+$592.0K
Aligos Therapeutics Inc1,630,0001,260,000-370,000$1.60M$441.0K0.10%-$1.16M
Reneo Pharmaceuticals Inc0165,000+165,000$0$249.2K0.06%+$249.2K
Compass Therapeutics, Inc.(CMPX)3,170,0000-3,170,000$6.28M$0—-$6.28M
Context Therapeutics Inc.(CNTX)1,108,3570-1,108,357$1.53M$0—-$1.53M
Crinetics Pharmaceuticals Inc210,0000-210,000$9.83M$0—-$9.83M
Glaukos Corporation(GKOS)8,5760-8,576$808.6K$0—-$808.6K
Larimar Therapeutics, Inc.(LRMR)174,4130-174,413$1.32M$0—-$1.32M
Morphosys AgADS65,0000-65,000$1.18M$0—-$1.18M
Nyxoah S ASHS
SHS
320,0000-320,000$4.32M$0—-$4.32M
Precigen, Inc.(PGEN)947,5000-947,500$1.37M$0—-$1.37M
REPARE THERAPEUTICS iNC67,5610-67,561$318.2K$0—-$318.2K
Revance Therapeutics Inc785,0000-785,000$3.86M$0—-$3.86M
Zentalis Pharmaceuticals, Inc.(ZNTL)200,0000-200,000$3.15M$0—-$3.15M
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Opaleye Management Inc. — 13F Holdings — Q2 2024 | TickerTrail