Securities ▲▼ | Shares | Value | |||||
|---|---|---|---|---|---|---|---|
Q3 2025 ▲▼ | Q4 2025 ▲▼ | Change ▲▼ | Q3 2025 ▲▼ | Q4 2025 ▲▼ | Weight (%) ▲▼ | Change ▲▼ | |
| Harrow, Inc.(HROW) | 3,905,000 | 3,905,000 | 0 | $188.14M | $191.34M | 25.25% | +$3.20M |
| Liquidia Corporation(LQDA) | 2,615,000 | 2,435,000 | -180,000 | $59.47M | $84.98M | 11.21% | +$25.52M |
| Eton Pharmaceuticals, Inc.(ETON) | 2,860,000 | 2,860,000 | 0 | $62.15M | $48.36M | 6.38% | -$13.79M |
| Rhythm Pharmaceuticals, Inc.(RYTM) | 461,700 | 330,000 | -131,700 | $46.63M | $35.32M | 4.66% | -$11.30M |
| Apogee Therapeutics Inc | 363,257 | 388,257 | +25,000 | $14.43M | $29.31M | 3.87% | +$14.87M |
| SANUWAVE Health, Inc.(SNWV) | 980,000 | 981,267 | +1,267 | $36.73M | $29.28M | 3.86% | -$7.45M |
| Stoke Therapeutics, Inc.(STOK) | 682,017 | 695,000 | +12,983 | $16.03M | $22.06M | 2.91% | +$6.03M |
| Ocular Therapeutix, Inc.(OCUL) | 1,595,000 | 1,595,000 | 0 | $18.65M | $19.36M | 2.55% | +$717.8K |
| Sol Gel TechnologiesSHS NEW SHS NEW | 204,835 | 453,739 | +248,904 | $5.97M | $19.12M | 2.52% | +$13.15M |
| CG Oncology, Inc.(CGON) | 410,000 | 410,000 | 0 | $16.51M | $17.02M | 2.25% | +$508.4K |
| TG Therapeutics, Inc.(TGTX) | 535,000 | 535,000 | 0 | $19.33M | $15.95M | 2.10% | -$3.38M |
| Disc Medicine, Inc.(IRON) | 193,773 | 200,000 | +6,227 | $12.80M | $15.88M | 2.10% | +$3.08M |
| Rezolute, Inc.(RZLT) | 903,442 | 6,287,156 | +5,383,714 | $8.49M | $14.84M | 1.96% | +$6.35M |
| Crescent Biopharma, Inc.(CBIO) | 0 | 1,178,300 | +1,178,300 | $0 | $13.97M | 1.84% | +$13.97M |
| Alkermes plcSHS(ALKS) | 450,000 | 490,000 | +40,000 | $13.50M | $13.71M | 1.81% | +$210.2K |
| Alpha Cognition Inc. Common Stock(ACOG) | 115,142 | 2,070,784 | +1,955,642 | $749.6K | $13.46M | 1.78% | +$12.71M |
| Annexon, Inc.(ANNX) | 2,600,000 | 2,600,000 | 0 | $7.93M | $13.05M | 1.72% | +$5.12M |
| Edgewise Therapeutics, Inc.(EWTX) | 500,000 | 500,000 | 0 | $8.11M | $12.41M | 1.64% | +$4.30M |
| Codexis, Inc.(CDXS) | 12,795,000 | 6,789,738 | -6,005,262 | $31.22M | $11.07M | 1.46% | -$20.15M |
| Protagonist Therapeutics Inc | 105,000 | 105,000 | 0 | $6.98M | $9.17M | 1.21% | +$2.20M |
| Gossamer Bio, Inc.(GOSS) | 2,725,000 | 2,720,000 | -5,000 | $7.17M | $8.43M | 1.11% | +$1.27M |
| MBX Biosciences, Inc.(MBX) | 253,000 | 260,000 | +7,000 | $4.43M | $8.20M | 1.08% | +$3.77M |
| Revolution Medicines, Inc.(RVMD) | 100,000 | 100,000 | 0 | $4.67M | $7.96M | 1.05% | +$3.29M |
| Xoma Corp Del | 255,087 | 292,590 | +37,503 | $9.83M | $7.78M | 1.03% | -$2.05M |
| Journey Medical Corporation(DERM) | 971,064 | 975,000 | +3,936 | $6.91M | $7.52M | 0.99% | +$603.3K |
| Karyopharm Therapeutics Inc.(KPTI) | 0 | 930,000 | +930,000 | $0 | $6.84M | 0.90% | +$6.84M |
| Jade Biosciences Inc | 0 | 427,608 | +427,608 | $0 | $6.60M | 0.87% | +$6.60M |
| UroGen Pharma Ltd.(URGN) | 0 | 268,423 | +268,423 | $0 | $6.29M | 0.83% | +$6.29M |
| Alumis Inc | 665,000 | 535,000 | -130,000 | $2.65M | $5.22M | 0.69% | +$2.57M |
| Perspective Therapeutics, Inc.(CATX) | 0 | 1,184,500 | +1,184,500 | $0 | $4.99M | 0.66% | +$4.99M |
| Voyager Therapeutics, Inc.(VYGR) | 0 | 1,196,904 | +1,196,904 | $0 | $4.70M | 0.62% | +$4.70M |
| Relmada Therapeutics, Inc.(RLMD) | 0 | 935,000 | +935,000 | $0 | $4.52M | 0.60% | +$4.52M |
| Tectonic Therapeutic, Inc.(TECX) | 0 | 214,747 | +214,747 | $0 | $4.48M | 0.59% | +$4.48M |
| Protalix BioTherapeutics, Inc.(PLX) | 2,580,556 | 2,478,176 | -102,380 | $5.73M | $4.46M | 0.59% | -$1.27M |
| Trevi Therapeutics, Inc.(TRVI) | 390,000 | 345,100 | -44,900 | $3.57M | $4.32M | 0.57% | +$752.2K |
| Fortress Biotech, Inc.(FBIO) | 0 | 1,090,000 | +1,090,000 | $0 | $3.99M | 0.53% | +$3.99M |
| Rocket Pharmaceuticals, Inc.(RCKT) | 0 | 955,000 | +955,000 | $0 | $3.35M | 0.44% | +$3.35M |
| MeiraGTx Holdings plc(MGTX) | 0 | 390,844 | +390,844 | $0 | $3.11M | 0.41% | +$3.11M |
| Rigel Pharmaceuticals, Inc.(RIGL) | 37,787 | 70,000 | +32,213 | $1.07M | $3.00M | 0.40% | +$1.93M |
| Zymeworks Inc.(ZYME) | 100,000 | 108,929 | +8,929 | $1.71M | $2.87M | 0.38% | +$1.16M |
| Assertio Holdings Inc | 0 | 285,000 | +285,000 | $0 | $2.58M | 0.34% | +$2.58M |
| Ventyx Biosciences Inc | 0 | 251,932 | +251,932 | $0 | $2.27M | 0.30% | +$2.27M |
| Opus Genetics, Inc.(IRD) | 1,100,000 | 1,120,000 | +20,000 | $1.81M | $2.25M | 0.30% | +$436.2K |
| Sutro Biopharma, Inc.(STRO) | 0 | 190,671 | +190,671 | $0 | $2.21M | 0.29% | +$2.21M |
| Cabaletta Bio, Inc.(CABA) | 808,882 | 900,000 | +91,118 | $1.89M | $1.97M | 0.26% | +$78.2K |
| Zentalis Pharmaceuticals, Inc.(ZNTL) | 316,550 | 1,400,906 | +1,084,356 | $478.0K | $1.89M | 0.25% | +$1.41M |
| Generation Bio Co | 0 | 310,000 | +310,000 | $0 | $1.76M | 0.23% | +$1.76M |
| BridgeBio Pharma, Inc.(BBIO) | 0 | 18,319 | +18,319 | $0 | $1.40M | 0.18% | +$1.40M |
| Enanta Pharmaceuticals, Inc.(ENTA) | 0 | 75,000 | +75,000 | $0 | $1.18M | 0.16% | +$1.18M |
| Q32 Bio Inc.(QTTB) | 0 | 213,363 | +213,363 | $0 | $708.4K | 0.09% | +$708.4K |
| Atea Pharmaceuticals, Inc.(AVIR) | 0 | 179,815 | +179,815 | $0 | $641.9K | 0.08% | +$641.9K |
| Silence Therapeutics plcADS(SLN) | 0 | 78,926 | +78,926 | $0 | $479.9K | 0.06% | +$479.9K |
| Rapt Therapeutics Inc | 0 | 150,000 | +150,000 | $0 | $213.4K | 0.03% | +$213.4K |
| Adagio Medical Holdings, Inc.(ADGM) | 110,571 | 18,444 | -92,127 | $214.5K | $19.2K | 0.00% | -$195.3K |
| ADC Therapeutics SASHS(ADCT) | 682,529 | 0 | -682,529 | $2.73M | $0 | — | -$2.73M |
| Arvinas, Inc.(ARVN) | 987,818 | 0 | -987,818 | $8.42M | $0 | — | -$8.42M |
| iBio, Inc.(IBIO) | 375,000 | 0 | -375,000 | $310.4K | $0 | — | -$310.4K |
| Immunome, Inc.(IMNM) | 3,185,000 | 0 | -3,185,000 | $37.30M | $0 | — | -$37.30M |
| Karyopharm Therapeutics IncNOTE 3 000 10 1 | 0 | 0 | 0 | $4.63M | $0 | — | -$4.63M |
| Larimar Therapeutics, Inc.(LRMR) | 3,720,867 | 0 | -3,720,867 | $10.56M | $0 | — | -$10.56M |
| PepGen Inc.(PEPG) | 75,000 | 0 | -75,000 | $346.5K | $0 | — | -$346.5K |
| Sarepta Therapeutics, Inc.(SRPT) | 585,000 | 0 | -585,000 | $11.27M | $0 | — | -$11.27M |
| Spyre Therapeutics, Inc.(SYRE) | 65,000 | 0 | -65,000 | $1.09M | $0 | — | -$1.09M |
| Treace Medical Concepts, Inc.(TMCI) | 702,245 | 0 | -702,245 | $4.71M | $0 | — | -$4.71M |